Gene model reviewed during 5.44
gene_with_stop_codon_read_through ; SO:0000697
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Gene model reviewed during 6.02
2.951 (sequence analysis)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\caps using the Feature Mapper tool.
caps mRNA expression is identical to the enhancer trap expression pattern.Expression is observed in four dorsal and 6 ventral muscles. In ventral longitudinal muscle 1, the expression is observed in a single nucleus of the syncytial muscle, near the contact site of the motorneuronal growth cone. Expression is also observed in the CNS in motoneurons aCC, RP2, RP5, and U.
In brains taken from 48hr APF pupae, caps is variably expressed in antennal lobe glomeruli, with some expressing high levels and others low.
caps protein is expressed in the medulla. Early on expression is uniform, but it becomes restricted to layers during pupal development. The terminals of photoreceptor R8 are located in a layer of caps expression, whereas the terminals of R7 are in a caps-negative layer.
The pattern ofexpression of the caps protein becomes restricted to the lateral regions of the wing disc during third instar in a pattern that is non-overlapping with the expression of the products of the Spalt genes, salm and salr.
GBrowse - Visual display of RNA-Seq signalsView Dmel\caps in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
caps expressed in the target layer does not mediate M3 layer recognition.
The RHR motif of the caps protein is essential for its role in tracheal development.
Panneural ectopic expression of caps results in pathfinding defects of motorneurons that innervate muscle 12.
Phenotypic and expression pattern analysis suggest a role for caps in selective synapse formation.
caps is an essential gene. Mutants show defects in neuromuscular target recognition.
Discovered in an enhancer trap screen.
Mutants die during late embryogenesis or soon after hatching. Morphology of muscle 12 synaptic terminal is abnormal.