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Gene Dmel\aay

General Information
Symbol	Dmel\aay	Species	D. melanogaster
Name	astray	Annotation symbol	CG3705
Feature type	protein_coding_gene	FlyBase ID	FBgn0023129
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67B5-67B5	Sequence location	3L:9,416,353..9,417,904 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene astray is referred to in FlyBase by the symbol Dmel\aay (CG3705, FBgn0023129). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphoserine phosphatase activity. There is experimental evidence that it is involved in the biological process: axon guidance; behavioral response to ethanol. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: HAD-like domain; HAD-superfamily hydrolase, subfamily IB, PSPase-like; Phosphoserine phosphatase SerB; Phosphoserine phosphatase, domain 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult midgut, larval hindgut, larval salivary gland, adult ovary, adult male reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1633488_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of aay. Gene sequence location is 3L:9416353..9417904.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	Sequence features BKN20653 BKN60546 BKN60031 HFA11320
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67B5-67B5   Limits computationally determined from genome sequence between P{EP}Hsp26EP3336&P{EP}Hsp26EP3315 and P{PZ}fry02240
Experimentally Determined Cytological Location
Cytogenetic map Notes References 67B1-67B10     (Prokopenko, 1999.8.3) 67B1-67B10     (Prokopenko, 1999.10.2) 67B1-67B10   (determined by in situ hybridisation)   (Szeged Stock Center, 1998-) 67B1-67B10   (determined by in situ hybridisation)   (Salzberg et al., 1997) 67B1-67B10   (determined by in situ hybridisation)   (Deak et al., 1997)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\aay for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) aay-RA FBtr0076457  NM_079277   1552   270
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein aay-PA   FBpp0076185   29.2   270   5.88     NP_524001   AAF50274
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phosphoserine phosphatase SerB (IPR004469) HAD-superfamily hydrolase, subfamily IB, PSPase-like (IPR006383) Phosphoserine phosphatase, domain 2 (IPR023190) HAD-like domain (IPR023214)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201605   AA263791   AA390995   AA392462   AA567592   AA698854   AA820172   AE014296 AAF50274   AF174664   AF174665   AF191498 AAF14696   AI064614   AI107607   AI109428   AI109611   AI135975   AI296978   AI297868   AI402341   AI403528   AI403530   AI405341   AI455353   AI456133   AI511874   AI519530   AI543817   AJ271817 CAB72249   AX260155   AY051689 AAK93113   BF487656   BF493157   BF493758   BF497024   BI171752   BI172960   BI212837   BI227845   BI237140   BI355317   BI364659   BI565413   BI565837   BI566455   BI570236   BI572080   BI573053   BI576746   BI582834   BI582913   BI589618   BI589627   BI590567   BI592015   BI592074   BI604504   BI605792   BI607009   BI612629   BI616572   BI616961   BI617693   BI617936   BI618985   BI619262   BI619655   BI621295   BI622975   BI624862   BI625526   BI625876   BI627188   BI627301   BI628498   BI629371   BI629455   BI629507   BI630091   BI630436   BI631064   BI631816   BP551413   CO189612   CO274368   CO283329   CO283408   CO297659   CO299436   CO300923   CO301740   CZ482262   EC057930   EC067666   EC074260   EC080657   EC083492   EC084935   EC090001   EC199709   EC210842   EC221320   EC225372   EV583487   EV585867   EV592385   GH786680
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9NFS2 Q9VSY6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 5 -- 8   pole cell | surrounding   (Prokopenko et al., 2000) amnioproctodeal invagination   (Prokopenko et al., 2000) embryonic stage 5 -- 10   organism | striped   (Prokopenko et al., 2000) embryonic stage 11 -- 12   organism | restricted & segmentally repeated   (Prokopenko et al., 2000) Comment:small segmentally repeated cell clusters embryonic stage 11 -- 16   embryonic foregut | anterior & restricted   (Prokopenko et al., 2000) embryonic stage 16 -- 17   embryonic/larval gut | faint   (Prokopenko et al., 2000)
Additional Descriptive Data
	aay transcript is expressed during embryonic stage 5 in 7 stripes capped on the dorsal side by a longitudinal stripe. Additionally, it is expressed in the region surrounding the pole cells and the invagination in which the pole cells migrate. At embryonic stage 11-12 aay transcript is expressed in segmentally repeated small clusters of cells, a ring of large cells around the anterior gut. The anterior gut expression persists through late embryogenesis; low levels of transcript are present in midgut and hindgut. (Prokopenko et al., 2000)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0023129    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0023129 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0023129 expression level Developmental Stage   Expression Level embryo 00-02hr    4676 embryo 02-04hr    4455 embryo 04-06hr    6417 embryo 06-08hr    4979 embryo 08-10hr    2497 embryo 10-12hr    2382 embryo 12-14hr    3453 embryo 14-16hr    4598 embryo 16-18hr    3830 embryo 18-20hr    3238 embryo 20-22hr    4093 embryo 22-24hr    4451 larva L1    4374 larva L2    4522 larva L3 12hr old    4086 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    1694 larva L3 puffstage 7-9    1284 white prepupae new    3083 white prepupae 12hr    1806 white prepupae 24hr    1602 pupae 2d postWPP    2188 pupae 3d postWPP    1697 pupae 4d postWPP    6615 adult male 01day    5142 adult male 05day    4550 adult male 30day    4500 adult female 01day    5308 adult female 05day    4798 adult female 30day    5597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4676) embryo 02-04hr  (4455) embryo 04-06hr  (6417) embryo 06-08hr  (4979) embryo 08-10hr  (2497) embryo 10-12hr  (2382) embryo 12-14hr  (3453) embryo 14-16hr  (4598) embryo 16-18hr  (3830) embryo 18-20hr  (3238) embryo 20-22hr  (4093) embryo 22-24hr  (4451) larva L1  (4374) larva L2  (4522) larva L3 12hr old  (4086) larva L3 puffstage 1-2  (1971) larva L3 puffstage 3-6  (1694) larva L3 puffstage 7-9  (1284) white prepupae new  (3083) white prepupae 12hr  (1806) white prepupae 24hr  (1602) pupae 2d postWPP  (2188) pupae 3d postWPP  (1697) pupae 4d postWPP  (6615) adult male 01day  (5142) adult male 05day  (4550) adult male 30day  (4500) adult female 01day  (5308) adult female 05day  (4798) adult female 30day  (5597) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4676) embryo 02-04hr  (4455) embryo 04-06hr  (6417) embryo 06-08hr  (4979) embryo 08-10hr  (2497) embryo 10-12hr  (2382) embryo 12-14hr  (3453) embryo 14-16hr  (4598) embryo 16-18hr  (3830) embryo 18-20hr  (3238) embryo 20-22hr  (4093) embryo 22-24hr  (4451) larva L1  (4374) larva L2  (4522) larva L3 12hr old  (4086) larva L3 puffstage 1-2  (1971) larva L3 puffstage 3-6  (1694) larva L3 puffstage 7-9    1284 white prepupae new  (3083) white prepupae 12hr  (1806) white prepupae 24hr  (1602) pupae 2d postWPP  (2188) pupae 3d postWPP  (1697) pupae 4d postWPP  (6615) adult male 01day  (5142) adult male 05day  (4550) adult male 30day  (4500) adult female 01day  (5308) adult female 05day  (4798) adult female 30day  (5597) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4676 embryo 02-04hr    4455 embryo 04-06hr    6417 embryo 06-08hr    4979 embryo 08-10hr    2497 embryo 10-12hr    2382 embryo 12-14hr    3453 embryo 14-16hr    4598 embryo 16-18hr    3830 embryo 18-20hr    3238 embryo 20-22hr    4093 embryo 22-24hr    4451 larva L1    4374 larva L2    4522 larva L3 12hr old    4086 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    1694 larva L3 puffstage 7-9    1284 white prepupae new    3083 white prepupae 12hr    1806 white prepupae 24hr    1602 pupae 2d postWPP    2188 pupae 3d postWPP    1697 pupae 4d postWPP    6615 adult male 01day    5142 adult male 05day    4550 adult male 30day    4500 adult female 01day    5308 adult female 05day    4798 adult female 30day    5597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4676 embryo 02-04hr    4455 embryo 04-06hr    6417 embryo 06-08hr    4979 embryo 08-10hr    2497 embryo 10-12hr    2382 embryo 12-14hr    3453 embryo 14-16hr    4598 embryo 16-18hr    3830 embryo 18-20hr    3238 embryo 20-22hr    4093 embryo 22-24hr    4451 larva L1    4374 larva L2    4522 larva L3 12hr old    4086 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    1694 larva L3 puffstage 7-9    1284 white prepupae new    3083 white prepupae 12hr    1806 white prepupae 24hr    1602 pupae 2d postWPP    2188 pupae 3d postWPP    1697 pupae 4d postWPP    6615 adult male 01day    5142 adult male 05day    4550 adult male 30day    4500 adult female 01day    5308 adult female 05day    4798 adult female 30day    5597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0023129 expression level Developmental Stage   Expression Level embryo 00-02hr    4676 embryo 02-04hr    4455 embryo 04-06hr    6417 embryo 06-08hr    4979 embryo 08-10hr    2497 embryo 10-12hr    2382 embryo 12-14hr    3453 embryo 14-16hr    4598 embryo 16-18hr    3830 embryo 18-20hr    3238 embryo 20-22hr    4093 embryo 22-24hr    4451 larva L1    4374 larva L2    4522 larva L3 12hr old    4086 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    1694 larva L3 puffstage 7-9    1284 white prepupae new    3083 white prepupae 12hr    1806 white prepupae 24hr    1602 pupae 2d postWPP    2188 pupae 3d postWPP    1697 pupae 4d postWPP    6615 adult male 01day    5142 adult male 05day    4550 adult male 30day    4500 adult female 01day    5308 adult female 05day    4798 adult female 30day    5597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4676) embryo 02-04hr  (4455) embryo 04-06hr  (6417) embryo 06-08hr  (4979) embryo 08-10hr  (2497) embryo 10-12hr  (2382) embryo 12-14hr  (3453) embryo 14-16hr  (4598) embryo 16-18hr  (3830) embryo 18-20hr  (3238) embryo 20-22hr  (4093) embryo 22-24hr  (4451) larva L1  (4374) larva L2  (4522) larva L3 12hr old  (4086) larva L3 puffstage 1-2  (1971) larva L3 puffstage 3-6  (1694) larva L3 puffstage 7-9  (1284) white prepupae new  (3083) white prepupae 12hr  (1806) white prepupae 24hr  (1602) pupae 2d postWPP  (2188) pupae 3d postWPP  (1697) pupae 4d postWPP  (6615) adult male 01day  (5142) adult male 05day  (4550) adult male 30day  (4500) adult female 01day  (5308) adult female 05day  (4798) adult female 30day  (5597) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4676) embryo 02-04hr  (4455) embryo 04-06hr  (6417) embryo 06-08hr  (4979) embryo 08-10hr  (2497) embryo 10-12hr  2382 embryo 12-14hr  (3453) embryo 14-16hr  (4598) embryo 16-18hr  (3830) embryo 18-20hr  (3238) embryo 20-22hr  (4093) embryo 22-24hr  (4451) larva L1  (4374) larva L2  (4522) larva L3 12hr old  (4086) larva L3 puffstage 1-2  1971 larva L3 puffstage 3-6  1694 larva L3 puffstage 7-9    1284 white prepupae new  (3083) white prepupae 12hr  1806 white prepupae 24hr  1602 pupae 2d postWPP  2188 pupae 3d postWPP  1697 pupae 4d postWPP  (6615) adult male 01day  (5142) adult male 05day  (4550) adult male 30day  (4500) adult female 01day  (5308) adult female 05day  (4798) adult female 30day  (5597) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4676 embryo 02-04hr    4455 embryo 04-06hr    6417 embryo 06-08hr    4979 embryo 08-10hr    2497 embryo 10-12hr    2382 embryo 12-14hr    3453 embryo 14-16hr    4598 embryo 16-18hr    3830 embryo 18-20hr    3238 embryo 20-22hr    4093 embryo 22-24hr    4451 larva L1    4374 larva L2    4522 larva L3 12hr old    4086 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    1694 larva L3 puffstage 7-9    1284 white prepupae new    3083 white prepupae 12hr    1806 white prepupae 24hr    1602 pupae 2d postWPP    2188 pupae 3d postWPP    1697 pupae 4d postWPP    6615 adult male 01day    5142 adult male 05day    4550 adult male 30day    4500 adult female 01day    5308 adult female 05day    4798 adult female 30day    5597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4676 embryo 02-04hr    4455 embryo 04-06hr    6417 embryo 06-08hr    4979 embryo 08-10hr    2497 embryo 10-12hr    2382 embryo 12-14hr    3453 embryo 14-16hr    4598 embryo 16-18hr    3830 embryo 18-20hr    3238 embryo 20-22hr    4093 embryo 22-24hr    4451 larva L1    4374 larva L2    4522 larva L3 12hr old    4086 larva L3 puffstage 1-2    1971 larva L3 puffstage 3-6    1694 larva L3 puffstage 7-9    1284 white prepupae new    3083 white prepupae 12hr    1806 white prepupae 24hr    1602 pupae 2d postWPP    2188 pupae 3d postWPP    1697 pupae 4d postWPP    6615 adult male 01day    5142 adult male 05day    4550 adult male 30day    4500 adult female 01day    5308 adult female 05day    4798 adult female 30day    5597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0023129    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0023129 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult midgut, larval hindgut, larval salivary gland, adult ovary, adult male reproductive system, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0023129 expression level Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules    577.1 Larval Fat Body    733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head    1282.7 Adult Eye    1129.15 Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop    735.4 Adult Midgut    251.1 Adult Hindgut    830.1 Adult Malpighian Tubules    792.8 Adult Fat Body    2253.9 Adult Salivary Gland    1036.7 Adult Heart    995.8 Adult VirginFemale Spermatheca    1878.2 Adult InseminatedFemale Spermatheca    1448.5 Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass    819.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules  (577.1) Larval Fat Body  (733.1) Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head  (1282.7) Adult Eye  (1129.15) Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop  (735.4) Adult Midgut    251.1 Adult Hindgut  (830.1) Adult Malpighian Tubules  (792.8) Adult Fat Body  (2253.9) Adult Salivary Gland  (1036.7) Adult Heart  (995.8) Adult VirginFemale Spermatheca  (1878.2) Adult InseminatedFemale Spermatheca  (1448.5) Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass  (819.6) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules    577.1 Larval Fat Body    733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head  (1282.7) Adult Eye  (1129.15) Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop    735.4 Adult Midgut    251.1 Adult Hindgut    830.1 Adult Malpighian Tubules    792.8 Adult Fat Body  (2253.9) Adult Salivary Gland  1036.7 Adult Heart    995.8 Adult VirginFemale Spermatheca  (1878.2) Adult InseminatedFemale Spermatheca  (1448.5) Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass    819.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules    577.1 Larval Fat Body    733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head    1282.7 Adult Eye    1129.15 Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop    735.4 Adult Midgut    251.1 Adult Hindgut    830.1 Adult Malpighian Tubules    792.8 Adult Fat Body    2253.9 Adult Salivary Gland    1036.7 Adult Heart    995.8 Adult VirginFemale Spermatheca    1878.2 Adult InseminatedFemale Spermatheca    1448.5 Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass    819.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0023129 expression level Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules    577.1 Larval Fat Body    733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head    1282.7 Adult Eye    1129.15 Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop    735.4 Adult Midgut    251.1 Adult Hindgut    830.1 Adult Malpighian Tubules    792.8 Adult Fat Body    2253.9 Adult Salivary Gland    1036.7 Adult Heart    995.8 Adult VirginFemale Spermatheca    1878.2 Adult InseminatedFemale Spermatheca    1448.5 Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass    819.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules  577.1 Larval Fat Body  733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head  (1282.7) Adult Eye  (1129.15) Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop  735.4 Adult Midgut    251.1 Adult Hindgut  (830.1) Adult Malpighian Tubules  792.8 Adult Fat Body  (2253.9) Adult Salivary Gland  (1036.7) Adult Heart  (995.8) Adult VirginFemale Spermatheca  (1878.2) Adult InseminatedFemale Spermatheca  (1448.5) Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass  (819.6) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules    577.1 Larval Fat Body    733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head  1282.7 Adult Eye  1129.15 Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop    735.4 Adult Midgut    251.1 Adult Hindgut    830.1 Adult Malpighian Tubules    792.8 Adult Fat Body  (2253.9) Adult Salivary Gland  1036.7 Adult Heart    995.8 Adult VirginFemale Spermatheca  (1878.2) Adult InseminatedFemale Spermatheca  1448.5 Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass    819.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    241.85 Larval Midgut    468.8 Larval Hindgut    195.5 Larval Malpighian Tubules    577.1 Larval Fat Body    733.1 Larval Salivary Gland    198.2 Larval Trachea    56.175 Larval Carcass    231.275 Adult Head    1282.7 Adult Eye    1129.15 Adult Brain    426.8 Adult Thoracic-Abdominal Ganglion    484.9 Adult Crop    735.4 Adult Midgut    251.1 Adult Hindgut    830.1 Adult Malpighian Tubules    792.8 Adult Fat Body    2253.9 Adult Salivary Gland    1036.7 Adult Heart    995.8 Adult VirginFemale Spermatheca    1878.2 Adult InseminatedFemale Spermatheca    1448.5 Adult Ovary    411 Adult Testis    131.1 Adult Male Accessory Gland    489.7 Adult Carcass    819.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1282.7   NA  Eye    1129.15   NA  Brain    426.8   241.85  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    484.9   NA  Crop    735.4   468.8  Midgut    251.1   195.5  Hindgut    830.1   577.1  Malpighian Tubules    792.8   733.1  Fat Body    2253.9   198.2  Salivary Gland    1036.7   NA  Heart    995.8   56.175  Trachea    NA   NA  VirginFemale Spermatheca    1878.2   NA  InseminatedFemale Spermatheca    1448.5   NA  Ovary    411   NA  Testis    131.1   NA  Male Accessory Gland    489.7   231.275  Carcass    819.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_26
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023129 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3705-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for aay Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pharate adult stage | recessive aayS042314 lethal | recessive aayS042314 viable, with Scer\GAL4pnr-MD237 aayGD13243 Other Phenotypes Allele chemical resistant | conditional aayS042314 hyperactive | conditional aayS042314 Phenotype manifest in Allele intersegmental nerve | embryonic stage aayS042314
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of aay Class Mutagen Stocks Known lesion aaye04497 piggyBac transposase 1 -- aayS042314 Delta2-3 P-element activity 1 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of aay Class Mutagen Stocks Known lesion aayGD13243 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes aayHM05064 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes aayKK100557 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)AC1 (Szeged Stock Center, 1998-, Salzberg et al., 1997) Df(3L)BSC35 (Andrade and Cook, 2003.6.2) Df(3L)BSC113 (Andrade and Cook, 2005.7.22)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13243} NA P{KK100557} NA P{TRiP.HM05064} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}aaye04497 NA insertion of enhancer trap P{lacW}aayS042314 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
axon guidance inferred from mutant phenotype (Prokopenko et al., 2000) behavioral response to ethanol inferred from mutant phenotype (Kong et al., 2010)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
phosphoserine phosphatase activity inferred from sequence or structural similarity (Prokopenko, 1999.10.2) inferred from sequence or structural similarity with EMBL:Y10275 (FlyBase, 1992-) non-traceable author statement (Prokopenko et al., 2000)
Biological Process
CV term Evidence References
L-serine biosynthetic process inferred from electronic annotation with InterPro:IPR004469 (FlyBase Curators et al., 2004-) non-traceable author statement (Prokopenko et al., 2000) peripheral nervous system development traceable author statement (Prokopenko et al., 2000)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions aay allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64479 DroID - A comprehensive database of gene and protein interactions. • FBgn0023129 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39085
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10695 Dere\GG15374 Dgri\GH15137 Dmoj\GI12074 Dper\GL22628 Dpse\GA17627 Dsec\GM25146 Dsim\GD14180 Dvir\GJ13344 Dwil\GK17158 Dyak\GE20838
Curated drosophilid orthologs	Dpse\GA17627
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001100-PB Aedes aegypti (mosquito) AGAP012247-PA Anopheles gambiae (mosquito) XP_396130.2 Apis mellifera (honey bee) XP_001945848.1 Acyrthosiphon pisum (pea aphid) At1g18640.1 Arabidopsis thaliana (wall cress) 12318 Batrachochytrium dendrobatidis (chytrid fungus) 122455 Branchiostoma floridae (lancelet) BGIBMGA009814-PA Bombyx mori (silk worm) ENSBTAP00000017392 Bos taurus (bovine) CAL0002335 Candida albicans (a form of yeast) CN11678 Caenorhabditis brenneri (small nematode) CN26452 Caenorhabditis brenneri (small nematode) CBP32914 Caenorhabditis briggsae (nematode) CE39453 Caenorhabditis elegans (worm) ENSCAFP00000014881 Canis familiaris (dog) CAGL0K00825g Candida glabrata (haploid yeast) ENSCINP00000026491 Ciona intestinalis (sea squirt) JA13532 Caenorhabditis japonica (nematode) CPIJ005707 Culex pipens (mosquito) ENSCPOP00000015228 Cavia porcellus (guinea pig) 153520 Chlamidomonas reinhardtii (green alga) RP38858 Caenorhabditis remanei (nematode) ENSCSAVP00000013307 Ciona savignyi (sedentary tunicate) 159753 Capitella spl (polychaete worm) DDB0230054 Dictyostelium discoideum (amoeba) DEHA2G03850g Debaryomyces Hansenii (yeast) 300856 Daphnia pulex (daphnia) ENSDARP00000058992 Danio rerio (zebra fish) ENSECAP00000018396 Equus caballus (horse) NP_418805.1 Escherichia coli K12 (bacteria) ENSGACP00000011745 Gymnopilus aculeatus (mushroom) ENSGALP00000003767 Gallus gallus (chicken) 83507 Hypsipyla robusta (cedar shoot borer) ENSP00000275605 Homo sapiens (human) ISCW003612-PA Ixodes scapularis (deer tick) KLLA0E16369g Kluyveromyces lactis (yeast) 164153 Lottia gigantea (owl limpet) 16456 Monocosta brevicollis (choanoflagellate) ENSMODP00000008168 Monodelphis domestica (gray opossum) ENSMUSP00000112738 Mus musculus (house mouse) 209120 Nematostella vectensis (starlet anemone) XP_001607548.1 Nasonia vitripennis (wasp) ENSOANP00000028697 Ornithorynchus anatinus (platypus) ENSORLP00000009771 Oryzias latipes (japanese killifish) LOC_Os12g31820.1 Oryza sativa (asian rice) 18250 Ostreococcus tauri (green alga) PP23092 Pristionchus pacificus (nematode) 134750 Physcomitrella patens (moss) ENSPPYP00000019666 Pongo pygmaeus (orangutan) 83432 Phytophthora ramorum (sudden oak death pathogen) 109495 Phytophthora sojae (root rot pathogen) 569934 Populus trichocarpa (black cottonwood) ENSPTRP00000032820 Pan troglodytes (chimpanzee) ENSRNOP00000001228 Rattus norvegicus (norway rat) 4825132 Sorghum bicolor (sorghum) YGR208W Saccharomyces cerevisiae (budding yeast) Smp_063340 Schistosoma mansoni (trematode parasite) SPBC3H7.07c Schizosaccharomyces pombe (fission yeast) 49601 Trichoplax adhaerens (metazoa) XP_001812661.1 Tribolium castaneum (red flour beetle) ENSTNIP00000022477 Tetraodon nigroviridis (green spotted pufferfish) 32137 Thalassiosira pseudonana (marine diatom) ENSTRUP00000039855 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000022202 Xenopus tropicalis (frog) YALI0B20438g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18343 NV11833 LH19290 ISCW003612 FBgn0238129 FBgn0219157 FBgn0200569 FBgn0185867 FBgn0182438 FBgn0180007 JGI_V11_300856 FBgn0077638 FBgn0160219 FBgn0134831 FBgn0122612 FBgn0107626 FBgn0087736 CPIJ005707 BGIBMGA009814 ACYPI000304 GB10941 AGAP012247 AAEL001100 PHUM545350 GLEAN_07208
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	28577 y1 v1; P{TRiP.HM05064}attP2/TM3, Sb1 4548 y1 w67c23; P{lacW}aayS042314/TM3, Sb1 Ser1
Harvard	- PBac{RB}aaye04497
VDRC	v23179 w1118; P{GD13243}v23179
Genomic Clones ( 1 )
	BACR01E20 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 97 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD23646
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01455 AT02095 AT11071 AT22661 GH05078 GH05376 GH08622 GH08849 GH13931 GH21532 GH22988 GH22990 GH25312 GM30362 HL01504 HL05810 LD04659 LD06953 LD09949 LD11335 LD35988 LD38930 LD39154 LD43423 LP11115 LP12306 RE13589 RE15673 RE18081 RE25225 RE33309 RE49826 RH02523 RH03078 RH03089 RH04207 RH07420 RH08743 RH09607 RH09689 RH21250 RH21337 RH33376 RH36004 RH41563 RH46577 RH47146 RH48104 RH48422 RH49940 RH50262 RH50732 RH52615 RH55026 RH56928 RH58226 RH58328 RH58384 RH59056 RH59478 RH60469 RH61465 RH63182 RH63664 RH64571 RH65972 RH66377 RH68424 RH68572 RH69894 RH71749 RH73984
Other clones	12421 30786 43442 43491 47395 58799 103428 177329 272896 CK01.50A.G2 CK01.55C.E11 Dmel_dig_001571_0628_1733 Dmel_dig_020005_0636_2308 Dmel_neb_007499_0691_0894 EK044720 EK113914 EK162854 EK163055 EK170306 EK175444 EK179705 EK182039 FGM212G02 RP003418035
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0023129 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39085
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: aay anon-WO0172774.117 (FlyBase, 1996-)
Additional comments	Source for merge of aay anon-WO0172774.117 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Candidate gene for quantitative trait (QTL) locus determining bristle number. (Nuzhdin et al., 1999) Gene identified during a P{lacW} screen shown to exhibit aberrant neuronal connections. (Salzberg et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079277 RefSeq (Proteins) • NP_524001 DDBJ / EMBL / GenBank • AA820172 AAF14696 AAF50274 AAK93113 AF174664 AF174665 AF191498 AI455353 AJ271817 AX260155 AY051689 CAB72249 CZ482262 Entrez Gene - A searchable database of RefSeq genes. • 39085 UniProtKB/TrEMBL • Q9NFS2 Q9VSY6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phosphoserine phosphatase SerB (IPR004469) HAD-superfamily hydrolase, subfamily IB, PSPase-like (IPR006383) Phosphoserine phosphatase, domain 2 (IPR023190) HAD-like domain (IPR023214)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64479 DroID - A comprehensive database of gene and protein interactions. • FBgn0023129 DRSC - Results from RNAi screens. • FBgn0023129 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023129 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3705-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0023129 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39085 InParanoid A subset of ortholog calls from InParanoid. • AAEL001100-PB Aedes aegypti (mosquito) AGAP012247-PA Anopheles gambiae (mosquito) XP_396130.2 Apis mellifera (honey bee) XP_001945848.1 Acyrthosiphon pisum (pea aphid) At1g18640.1 Arabidopsis thaliana (wall cress) 12318 Batrachochytrium dendrobatidis (chytrid fungus) 122455 Branchiostoma floridae (lancelet) BGIBMGA009814-PA Bombyx mori (silk worm) ENSBTAP00000017392 Bos taurus (bovine) CAL0002335 Candida albicans (a form of yeast) CN11678 Caenorhabditis brenneri (small nematode) CN26452 Caenorhabditis brenneri (small nematode) CBP32914 Caenorhabditis briggsae (nematode) CE39453 Caenorhabditis elegans (worm) ENSCAFP00000014881 Canis familiaris (dog) CAGL0K00825g Candida glabrata (haploid yeast) ENSCINP00000026491 Ciona intestinalis (sea squirt) JA13532 Caenorhabditis japonica (nematode) CPIJ005707 Culex pipens (mosquito) ENSCPOP00000015228 Cavia porcellus (guinea pig) 153520 Chlamidomonas reinhardtii (green alga) RP38858 Caenorhabditis remanei (nematode) ENSCSAVP00000013307 Ciona savignyi (sedentary tunicate) 159753 Capitella spl (polychaete worm) DDB0230054 Dictyostelium discoideum (amoeba) DEHA2G03850g Debaryomyces Hansenii (yeast) 300856 Daphnia pulex (daphnia) ENSDARP00000058992 Danio rerio (zebra fish) ENSECAP00000018396 Equus caballus (horse) NP_418805.1 Escherichia coli K12 (bacteria) ENSGACP00000011745 Gymnopilus aculeatus (mushroom) ENSGALP00000003767 Gallus gallus (chicken) 83507 Hypsipyla robusta (cedar shoot borer) ENSP00000275605 Homo sapiens (human) ISCW003612-PA Ixodes scapularis (deer tick) KLLA0E16369g Kluyveromyces lactis (yeast) 164153 Lottia gigantea (owl limpet) 16456 Monocosta brevicollis (choanoflagellate) ENSMODP00000008168 Monodelphis domestica (gray opossum) ENSMUSP00000112738 Mus musculus (house mouse) 209120 Nematostella vectensis (starlet anemone) XP_001607548.1 Nasonia vitripennis (wasp) ENSOANP00000028697 Ornithorynchus anatinus (platypus) ENSORLP00000009771 Oryzias latipes (japanese killifish) LOC_Os12g31820.1 Oryza sativa (asian rice) 18250 Ostreococcus tauri (green alga) PP23092 Pristionchus pacificus (nematode) 134750 Physcomitrella patens (moss) ENSPPYP00000019666 Pongo pygmaeus (orangutan) 83432 Phytophthora ramorum (sudden oak death pathogen) 109495 Phytophthora sojae (root rot pathogen) 569934 Populus trichocarpa (black cottonwood) ENSPTRP00000032820 Pan troglodytes (chimpanzee) ENSRNOP00000001228 Rattus norvegicus (norway rat) 4825132 Sorghum bicolor (sorghum) YGR208W Saccharomyces cerevisiae (budding yeast) Smp_063340 Schistosoma mansoni (trematode parasite) SPBC3H7.07c Schizosaccharomyces pombe (fission yeast) 49601 Trichoplax adhaerens (metazoa) XP_001812661.1 Tribolium castaneum (red flour beetle) ENSTNIP00000022477 Tetraodon nigroviridis (green spotted pufferfish) 32137 Thalassiosira pseudonana (marine diatom) ENSTRUP00000039855 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000022202 Xenopus tropicalis (frog) YALI0B20438g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39085 modMine - Data generated by the modENCODE project. • FBgn0023129 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18343 NV11833 LH19290 ISCW003612 FBgn0238129 FBgn0219157 FBgn0200569 FBgn0185867 FBgn0182438 FBgn0180007 JGI_V11_300856 FBgn0077638 FBgn0160219 FBgn0134831 FBgn0122612 FBgn0107626 FBgn0087736 CPIJ005707 BGIBMGA009814 ACYPI000304 GB10941 AGAP012247 AAEL001100 PHUM545350 GLEAN_07208
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	0423/14 (Deak et al., 1997) aay (Harvey et al., 2008, Kong et al., 2010) anon-WO0172774.117   CG3705 (Perkins et al., 2009, Keleman et al., 2009.8.5)
Name Synonym	3-phosphoserine phosphatase (Kong et al., 2010) astray (Salzberg et al., 1997, Harvey et al., 2008, Kong et al., 2010) Astray (Rollmann et al., 2008)
Secondary FlyBase IDs
	FBgn0046476
References ( 42 )
Generate a list of	All references relating to this gene ( 42 )
List References by type	Research paper  ( 18 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 1 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 3 ) Computer file  ( 4 ) Curated genome annotation  ( 1 ) Patent  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 1 )
	Kong et al., 2010, Alcoholism, Clin. Exp. Res. 34(2): 302--316 Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila. [FBrf0209720] Show all research papers ...