E1, UBA-1, l(2)03405, Uba 1, l(2)05642
Ubiquitin-activating enzyme, E1, activates and transfers ubiquitin to ubiquitin-conjugating enzymes, tumor suppressor
Please see the JBrowse view of Dmel\Uba1 for information on other features
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Gene model reviewed during 5.42
Gene model reviewed during 5.49
Low-frequency RNA-Seq exon junction(s) not annotated.
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Uba1 using the Feature Mapper tool.
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
GBrowse - Visual display of RNA-Seq signals
View Dmel\Uba1 in GBrowse 22-61
2-61
2-59.5
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Uba1 CG1782
Source for merge of: Uba1 l(2)03405
Source for merge of: Uba1 l(2)05642
Uba1 controls apoptosis autonomously and tissue growth non-autonomously.
Expression is enriched in embryonic gonads.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Uba1 is required for axon pruning during metamorphosis.
Mutants isolated in a screen of the second chromosome identifying genes affecting disc morphology.