A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\Prosα7

General Information
SymbolDmel\Prosα7SpeciesD. melanogaster
NameProteasome α7 subunitAnnotation symbolCG1519
Feature typeprotein_coding_geneFlyBase IDFBgn0023175
Gene Model StatusCurrent Stock availability 4 publicly available
Also Known AsProsalpha7
Genomic Location
Chromosome (arm)2RRecombination map
Cytogenetic map46B4-46B4Sequence location2R:5,734,141..5,735,339 [-]

Genomic Maps

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modENCODE GBrowse
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Automatically generated summary

See sections below for more information
The gene Proteasome α7 subunit is referred to in FlyBase by the symbol Dmel\Prosα7 (CG1519, FBgn0023175). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: endopeptidase activity. There is experimental evidence that it is involved in the biological process: response to DNA damage stimulus. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Proteasome A-type subunit; Proteasome, alpha-subunit, conserved site; Proteasome, subunit alpha/beta. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult crop, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult hindgut. Comments on Affy2 ProbeSet: ProbeSet 1634795_a_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Prosalpha7. Gene sequence location is 2R:5734141..5735339.
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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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FB2011_10
Controlled Vocabulary Terms
FB2012_01
References
Sequence features
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
46B4-46B4  
Limits computationally determined from genome sequence between P{lacW}l(2)k05420k05420 and P{lacW}l(2)k07803k07803&P{lacW}l(2)k08816k08816  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\Prosα7 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0088479 FBtr0088482 FBtr0089998 FBtr0088373 FBpp0087563 FBpp0087566 FBpp0089041 FBpp0087461 FBti0125068 FBti0047792 FBti0103934 FBti0027288 FBti0034313 FBti0109565 FBti0025913 FBti0054644 FBti0126678
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0089998
  974
  253
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0089041  
27.7  
253  
5.41  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
MEROPS - An information resource for peptidases and the proteins that inhibit them
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view Orc6-RA Prosalpha7-RA CG1671-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0023175


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0023175
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0023175 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 22863
embryo 02-04hr
 
 24452
embryo 04-06hr
 
 10876
embryo 06-08hr
 
 9025
embryo 08-10hr
 
 8956
embryo 10-12hr
 
 7733
embryo 12-14hr
 
 5044
embryo 14-16hr
 
 3885
embryo 16-18hr
 
 2958
embryo 18-20hr
 
 2465
embryo 20-22hr
 
 2607
embryo 22-24hr
 
 2743
larva L1
 
 3972
larva L2
 
 8458
larva L3 12hr old
 
 7069
larva L3 puffstage 1-2
 
 9976
larva L3 puffstage 3-6
 
 15451
larva L3 puffstage 7-9
 
 20534
white prepupae new
 
 20638
white prepupae 12hr
 
 10048
white prepupae 24hr
 
 11695
pupae 2d postWPP
 
 8599
pupae 3d postWPP
 
 6903
pupae 4d postWPP
 
 8614
adult male 01day
 
 8520
adult male 05day
 
 9839
adult male 30day
 
 8666
adult female 01day
 
 9141
adult female 05day
 
 14606
adult female 30day
 
 14513
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (22863)
embryo 02-04hr
 (24452)
embryo 04-06hr
 (10876)
embryo 06-08hr
 (9025)
embryo 08-10hr
 (8956)
embryo 10-12hr
 (7733)
embryo 12-14hr
 (5044)
embryo 14-16hr
 (3885)
embryo 16-18hr
 (2958)
embryo 18-20hr
 (2465)
embryo 20-22hr
 (2607)
embryo 22-24hr
 (2743)
larva L1
 (3972)
larva L2
 (8458)
larva L3 12hr old
 (7069)
larva L3 puffstage 1-2
 (9976)
larva L3 puffstage 3-6
 (15451)
larva L3 puffstage 7-9
 (20534)
white prepupae new
 (20638)
white prepupae 12hr
 (10048)
white prepupae 24hr
 (11695)
pupae 2d postWPP
 (8599)
pupae 3d postWPP
 (6903)
pupae 4d postWPP
 (8614)
adult male 01day
 (8520)
adult male 05day
 (9839)
adult male 30day
 (8666)
adult female 01day
 (9141)
adult female 05day
 (14606)
adult female 30day
 (14513)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (22863)
embryo 02-04hr
 (24452)
embryo 04-06hr
 (10876)
embryo 06-08hr
 (9025)
embryo 08-10hr
 (8956)
embryo 10-12hr
 (7733)
embryo 12-14hr
 (5044)
embryo 14-16hr
 (3885)
embryo 16-18hr
 (2958)
embryo 18-20hr
 (2465)
embryo 20-22hr
 (2607)
embryo 22-24hr
 (2743)
larva L1
 (3972)
larva L2
 (8458)
larva L3 12hr old
 (7069)
larva L3 puffstage 1-2
 (9976)
larva L3 puffstage 3-6
 (15451)
larva L3 puffstage 7-9
 (20534)
white prepupae new
 (20638)
white prepupae 12hr
 (10048)
white prepupae 24hr
 (11695)
pupae 2d postWPP
 (8599)
pupae 3d postWPP
 (6903)
pupae 4d postWPP
 (8614)
adult male 01day
 (8520)
adult male 05day
 (9839)
adult male 30day
 (8666)
adult female 01day
 (9141)
adult female 05day
 (14606)
adult female 30day
 (14513)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 (22863)
embryo 02-04hr
 (24452)
embryo 04-06hr
 (10876)
embryo 06-08hr
 
 9025
embryo 08-10hr
 
 8956
embryo 10-12hr
 
 7733
embryo 12-14hr
 
 5044
embryo 14-16hr
 
 3885
embryo 16-18hr
 
 2958
embryo 18-20hr
 
 2465
embryo 20-22hr
 
 2607
embryo 22-24hr
 
 2743
larva L1
 
 3972
larva L2
 
 8458
larva L3 12hr old
 
 7069
larva L3 puffstage 1-2
 
 9976
larva L3 puffstage 3-6
 (15451)
larva L3 puffstage 7-9
 (20534)
white prepupae new
 (20638)
white prepupae 12hr
 10048
white prepupae 24hr
 (11695)
pupae 2d postWPP
 
 8599
pupae 3d postWPP
 
 6903
pupae 4d postWPP
 
 8614
adult male 01day
 
 8520
adult male 05day
 
 9839
adult male 30day
 
 8666
adult female 01day
 
 9141
adult female 05day
 (14606)
adult female 30day
 (14513)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 22863
embryo 02-04hr
 
 24452
embryo 04-06hr
 
 10876
embryo 06-08hr
 
 9025
embryo 08-10hr
 
 8956
embryo 10-12hr
 
 7733
embryo 12-14hr
 
 5044
embryo 14-16hr
 
 3885
embryo 16-18hr
 
 2958
embryo 18-20hr
 
 2465
embryo 20-22hr
 
 2607
embryo 22-24hr
 
 2743
larva L1
 
 3972
larva L2
 
 8458
larva L3 12hr old
 
 7069
larva L3 puffstage 1-2
 
 9976
larva L3 puffstage 3-6
 
 15451
larva L3 puffstage 7-9
 
 20534
white prepupae new
 
 20638
white prepupae 12hr
 
 10048
white prepupae 24hr
 
 11695
pupae 2d postWPP
 
 8599
pupae 3d postWPP
 
 6903
pupae 4d postWPP
 
 8614
adult male 01day
 
 8520
adult male 05day
 
 9839
adult male 30day
 
 8666
adult female 01day
 
 9141
adult female 05day
 
 14606
adult female 30day
 
 14513
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0023175 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 22863
embryo 02-04hr
 
 24452
embryo 04-06hr
 
 10876
embryo 06-08hr
 
 9025
embryo 08-10hr
 
 8956
embryo 10-12hr
 
 7733
embryo 12-14hr
 
 5044
embryo 14-16hr
 
 3885
embryo 16-18hr
 
 2958
embryo 18-20hr
 
 2465
embryo 20-22hr
 
 2607
embryo 22-24hr
 
 2743
larva L1
 
 3972
larva L2
 
 8458
larva L3 12hr old
 
 7069
larva L3 puffstage 1-2
 
 9976
larva L3 puffstage 3-6
 
 15451
larva L3 puffstage 7-9
 
 20534
white prepupae new
 
 20638
white prepupae 12hr
 
 10048
white prepupae 24hr
 
 11695
pupae 2d postWPP
 
 8599
pupae 3d postWPP
 
 6903
pupae 4d postWPP
 
 8614
adult male 01day
 
 8520
adult male 05day
 
 9839
adult male 30day
 
 8666
adult female 01day
 
 9141
adult female 05day
 
 14606
adult female 30day
 
 14513
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (22863)
embryo 02-04hr
 (24452)
embryo 04-06hr
 (10876)
embryo 06-08hr
 (9025)
embryo 08-10hr
 (8956)
embryo 10-12hr
 (7733)
embryo 12-14hr
 (5044)
embryo 14-16hr
 (3885)
embryo 16-18hr
 (2958)
embryo 18-20hr
 (2465)
embryo 20-22hr
 (2607)
embryo 22-24hr
 (2743)
larva L1
 (3972)
larva L2
 (8458)
larva L3 12hr old
 (7069)
larva L3 puffstage 1-2
 (9976)
larva L3 puffstage 3-6
 (15451)
larva L3 puffstage 7-9
 (20534)
white prepupae new
 (20638)
white prepupae 12hr
 (10048)
white prepupae 24hr
 (11695)
pupae 2d postWPP
 (8599)
pupae 3d postWPP
 (6903)
pupae 4d postWPP
 (8614)
adult male 01day
 (8520)
adult male 05day
 (9839)
adult male 30day
 (8666)
adult female 01day
 (9141)
adult female 05day
 (14606)
adult female 30day
 (14513)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (22863)
embryo 02-04hr
 (24452)
embryo 04-06hr
 (10876)
embryo 06-08hr
 (9025)
embryo 08-10hr
 (8956)
embryo 10-12hr
 (7733)
embryo 12-14hr
 (5044)
embryo 14-16hr
 (3885)
embryo 16-18hr
 (2958)
embryo 18-20hr
 2465
embryo 20-22hr
 (2607)
embryo 22-24hr
 (2743)
larva L1
 (3972)
larva L2
 (8458)
larva L3 12hr old
 (7069)
larva L3 puffstage 1-2
 (9976)
larva L3 puffstage 3-6
 (15451)
larva L3 puffstage 7-9
 (20534)
white prepupae new
 (20638)
white prepupae 12hr
 (10048)
white prepupae 24hr
 (11695)
pupae 2d postWPP
 (8599)
pupae 3d postWPP
 (6903)
pupae 4d postWPP
 (8614)
adult male 01day
 (8520)
adult male 05day
 (9839)
adult male 30day
 (8666)
adult female 01day
 (9141)
adult female 05day
 (14606)
adult female 30day
 (14513)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 (22863)
embryo 02-04hr
 (24452)
embryo 04-06hr
 10876
embryo 06-08hr
 
 9025
embryo 08-10hr
 
 8956
embryo 10-12hr
 
 7733
embryo 12-14hr
 
 5044
embryo 14-16hr
 
 3885
embryo 16-18hr
 
 2958
embryo 18-20hr
 
 2465
embryo 20-22hr
 
 2607
embryo 22-24hr
 
 2743
larva L1
 
 3972
larva L2
 
 8458
larva L3 12hr old
 
 7069
larva L3 puffstage 1-2
 
 9976
larva L3 puffstage 3-6
 15451
larva L3 puffstage 7-9
 20534
white prepupae new
 (20638)
white prepupae 12hr
 10048
white prepupae 24hr
 11695
pupae 2d postWPP
 
 8599
pupae 3d postWPP
 
 6903
pupae 4d postWPP
 
 8614
adult male 01day
 
 8520
adult male 05day
 
 9839
adult male 30day
 
 8666
adult female 01day
 
 9141
adult female 05day
 14606
adult female 30day
 14513
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 22863
embryo 02-04hr
 
 24452
embryo 04-06hr
 
 10876
embryo 06-08hr
 
 9025
embryo 08-10hr
 
 8956
embryo 10-12hr
 
 7733
embryo 12-14hr
 
 5044
embryo 14-16hr
 
 3885
embryo 16-18hr
 
 2958
embryo 18-20hr
 
 2465
embryo 20-22hr
 
 2607
embryo 22-24hr
 
 2743
larva L1
 
 3972
larva L2
 
 8458
larva L3 12hr old
 
 7069
larva L3 puffstage 1-2
 
 9976
larva L3 puffstage 3-6
 
 15451
larva L3 puffstage 7-9
 
 20534
white prepupae new
 
 20638
white prepupae 12hr
 
 10048
white prepupae 24hr
 
 11695
pupae 2d postWPP
 
 8599
pupae 3d postWPP
 
 6903
pupae 4d postWPP
 
 8614
adult male 01day
 
 8520
adult male 05day
 
 9839
adult male 30day
 
 8666
adult female 01day
 
 9141
adult female 05day
 
 14606
adult female 30day
 
 14513
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0023175


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0023175
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult crop, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult hindgut.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0023175 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 1052
Larval Midgut
 
 1094.7
Larval Hindgut
 
 1053.2
Larval Malpighian Tubules
 
 2054.8
Larval Fat Body
 
 1306.1
Larval Salivary Gland
 
 1458.1
Larval Trachea
 
 1155.35
Larval Carcass
 
 1798.7
Adult Head
 
 469.7
Adult Eye
 
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 
 912.6
Adult Midgut
 
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 
 765.3
Adult Fat Body
 
 1606
Adult Salivary Gland
 
 530.5
Adult Heart
 
 1989.95
Adult VirginFemale Spermatheca
 
 654
Adult InseminatedFemale Spermatheca
 
 654.4
Adult Ovary
 
 1543.4
Adult Testis
 
 1255.4
Adult Male Accessory Gland
 
 683.7
Adult Carcass
 
 1258.2
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (1052)
Larval Midgut
 (1094.7)
Larval Hindgut
 (1053.2)
Larval Malpighian Tubules
 (2054.8)
Larval Fat Body
 (1306.1)
Larval Salivary Gland
 (1458.1)
Larval Trachea
 (1155.35)
Larval Carcass
 (1798.7)
Adult Head
 
 469.7
Adult Eye
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 (912.6)
Adult Midgut
 (735.9)
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 (765.3)
Adult Fat Body
 (1606)
Adult Salivary Gland
 530.5
Adult Heart
 (1989.95)
Adult VirginFemale Spermatheca
 (654)
Adult InseminatedFemale Spermatheca
 (654.4)
Adult Ovary
 (1543.4)
Adult Testis
 (1255.4)
Adult Male Accessory Gland
 (683.7)
Adult Carcass
 (1258.2)
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 1052
Larval Midgut
 (1094.7)
Larval Hindgut
 1053.2
Larval Malpighian Tubules
 (2054.8)
Larval Fat Body
 (1306.1)
Larval Salivary Gland
 (1458.1)
Larval Trachea
 (1155.35)
Larval Carcass
 (1798.7)
Adult Head
 
 469.7
Adult Eye
 
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 
 912.6
Adult Midgut
 
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 
 765.3
Adult Fat Body
 (1606)
Adult Salivary Gland
 
 530.5
Adult Heart
 (1989.95)
Adult VirginFemale Spermatheca
 
 654
Adult InseminatedFemale Spermatheca
 
 654.4
Adult Ovary
 (1543.4)
Adult Testis
 (1255.4)
Adult Male Accessory Gland
 
 683.7
Adult Carcass
 (1258.2)
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 1052
Larval Midgut
 
 1094.7
Larval Hindgut
 
 1053.2
Larval Malpighian Tubules
 
 2054.8
Larval Fat Body
 
 1306.1
Larval Salivary Gland
 
 1458.1
Larval Trachea
 
 1155.35
Larval Carcass
 
 1798.7
Adult Head
 
 469.7
Adult Eye
 
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 
 912.6
Adult Midgut
 
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 
 765.3
Adult Fat Body
 
 1606
Adult Salivary Gland
 
 530.5
Adult Heart
 
 1989.95
Adult VirginFemale Spermatheca
 
 654
Adult InseminatedFemale Spermatheca
 
 654.4
Adult Ovary
 
 1543.4
Adult Testis
 
 1255.4
Adult Male Accessory Gland
 
 683.7
Adult Carcass
 
 1258.2
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0023175 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 1052
Larval Midgut
 
 1094.7
Larval Hindgut
 
 1053.2
Larval Malpighian Tubules
 
 2054.8
Larval Fat Body
 
 1306.1
Larval Salivary Gland
 
 1458.1
Larval Trachea
 
 1155.35
Larval Carcass
 
 1798.7
Adult Head
 
 469.7
Adult Eye
 
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 
 912.6
Adult Midgut
 
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 
 765.3
Adult Fat Body
 
 1606
Adult Salivary Gland
 
 530.5
Adult Heart
 
 1989.95
Adult VirginFemale Spermatheca
 
 654
Adult InseminatedFemale Spermatheca
 
 654.4
Adult Ovary
 
 1543.4
Adult Testis
 
 1255.4
Adult Male Accessory Gland
 
 683.7
Adult Carcass
 
 1258.2
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (1052)
Larval Midgut
 (1094.7)
Larval Hindgut
 (1053.2)
Larval Malpighian Tubules
 (2054.8)
Larval Fat Body
 (1306.1)
Larval Salivary Gland
 (1458.1)
Larval Trachea
 (1155.35)
Larval Carcass
 (1798.7)
Adult Head
 
 469.7
Adult Eye
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 (912.6)
Adult Midgut
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 765.3
Adult Fat Body
 (1606)
Adult Salivary Gland
 530.5
Adult Heart
 (1989.95)
Adult VirginFemale Spermatheca
 654
Adult InseminatedFemale Spermatheca
 654.4
Adult Ovary
 (1543.4)
Adult Testis
 (1255.4)
Adult Male Accessory Gland
 683.7
Adult Carcass
 (1258.2)
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 1052
Larval Midgut
 1094.7
Larval Hindgut
 1053.2
Larval Malpighian Tubules
 (2054.8)
Larval Fat Body
 1306.1
Larval Salivary Gland
 1458.1
Larval Trachea
 1155.35
Larval Carcass
 (1798.7)
Adult Head
 
 469.7
Adult Eye
 
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 
 912.6
Adult Midgut
 
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 
 765.3
Adult Fat Body
 1606
Adult Salivary Gland
 
 530.5
Adult Heart
 (1989.95)
Adult VirginFemale Spermatheca
 
 654
Adult InseminatedFemale Spermatheca
 
 654.4
Adult Ovary
 1543.4
Adult Testis
 1255.4
Adult Male Accessory Gland
 
 683.7
Adult Carcass
 1258.2
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 1052
Larval Midgut
 
 1094.7
Larval Hindgut
 
 1053.2
Larval Malpighian Tubules
 
 2054.8
Larval Fat Body
 
 1306.1
Larval Salivary Gland
 
 1458.1
Larval Trachea
 
 1155.35
Larval Carcass
 
 1798.7
Adult Head
 
 469.7
Adult Eye
 
 508.475
Adult Brain
 
 348.2
Adult Thoracic-Abdominal Ganglion
 
 427.1
Adult Crop
 
 912.6
Adult Midgut
 
 735.9
Adult Hindgut
 
 477.4
Adult Malpighian Tubules
 
 765.3
Adult Fat Body
 
 1606
Adult Salivary Gland
 
 530.5
Adult Heart
 
 1989.95
Adult VirginFemale Spermatheca
 
 654
Adult InseminatedFemale Spermatheca
 
 654.4
Adult Ovary
 
 1543.4
Adult Testis
 
 1255.4
Adult Male Accessory Gland
 
 683.7
Adult Carcass
 
 1258.2
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 469.7
 
NA 
Eye
 
 508.475
 
NA 
Brain
 
 348.2
 
1052 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 427.1
 
NA 
Crop
 
 912.6
 
1094.7 
Midgut
 
 735.9
 
1053.2 
Hindgut
 
 477.4
 
2054.8 
Malpighian Tubules
 
 765.3
 
1306.1 
Fat Body
 
 1606
 
1458.1 
Salivary Gland
 
 530.5
 
NA 
Heart
 
 1989.95
 
1155.35 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 654
 
NA 
InseminatedFemale Spermatheca
 
 654.4
 
NA 
Ovary
 
 1543.4
 
NA 
Testis
 
 1255.4
 
NA 
Male Accessory Gland
 
 683.7
 
1798.7 
Carcass
 
 1258.2

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
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FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
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hide Summary of Allele Phenotypes
Lethality
Allele
Phenotype manifest in
Allele
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For All Classical Alleles Show

Allele of Prosα7ClassMutagenStocksKnown lesion
hide Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show

Allele of Prosα7ClassMutagenStocksKnown lesion
Prosα7GD34912 Yes
Prosα7HMS000681 Yes
Prosα7KK1092621 Yes
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Transgenic Constructs
Type of construct
Name
Expression data
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Type of insertions
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Expression data
insertion of enhancer trap
hide Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
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CV term
References
inferred from mutant phenotype
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hide Terms Based on Predictions or Assertions ( 5 terms )
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Interacts with
Please look at the allele data for full details of the genetic interactions
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BioGRID - A database of protein and genetic interactions
DPiM - DPiM, Drosophila Protein interaction Map
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
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InParanoid A subset of ortholog calls from InParanoid.
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Bloomington
VDRC
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Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
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Linkouts
DRSC - Results from RNAi screens.
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Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
MEROPS - An information resource for peptidases and the proteins that inhibit them
Linkouts
BioGRID - A database of protein and genetic interactions
DPiM - DPiM, Drosophila Protein interaction Map
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 14 )
Reported As
Symbol Synonym
alpha7_dm
Name Synonym
20s proteasome
20S proteasome
20S proteasome subunit alpha-7
Proteasome alpha7 subunit
Proteasome subunit alpha type-3
Proteasome α7 subunit
 
Secondary FlyBase IDs
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hide Recent research papers ( 3 )
Booker et al., 2011, BMC Genomics 12: 50
False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969]
Bader et al., 2010, Development 137(10): 1679--1688
A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila. [FBrf0210629]
Guenin et al., 2010, BMC Genomics 11: 47
Expression profiling of prospero in the Drosophila larval chemosensory organ: Between growth and outgrowth. [FBrf0210012]