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Gene Dmel\Pp4-19C

General Information
Symbol	Dmel\Pp4-19C	Species	D. melanogaster
Name	Protein phosphatase 19C	Annotation symbol	CG32505
Feature type	protein_coding_gene	FlyBase ID	FBgn0023177
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	PP4
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	19D1-19D1	Sequence location	X:20,292,114..20,295,045 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Protein phosphatase 19C is referred to in FlyBase by the symbol Dmel\Pp4-19C (CG32505, FBgn0023177). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process: M phase specific microtubule process; mitotic cell cycle; regulation of mitotic cell cycle; microtubule-based process; neurogenesis. 6 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Metallophosphoesterase domain; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1623506_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Pp4-19C. Gene sequence location is X:20292114..20295045.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Su et al., 2011, Sci. Signal. 4(180): ra43 Sequence features BKN60435 BKN23059 HFA20559 BKN60115 HFA21251
FB2011_10	References Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 19D1-19D1   Limits computationally determined from genome sequence between P{EP}amnEP1639&P{EP}amnEP367 and P{EP}CG1702EP1525
Experimentally Determined Cytological Location
Cytogenetic map Notes References 19C1-19C2     (Cohen, 1997.7.9) 19C1-19C2   (determined by in situ hybridisation)   (Helps et al., 1998)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Pp4-19C for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Pp4-19C-RA FBtr0077324  NM_080064   2175   307 Pp4-19C-RE FBtr0077325  NM_167703   2223   307
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Pp4-19C-PA   FBpp0077016   35.3   307   4.89     NP_524803   AAF50905 Pp4-19C-PE   FBpp0077017   35.3   307   4.89     NP_728342   AAN09547
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Metallophosphoesterase domain (IPR004843) Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (IPR006186)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246838   AA264958   AA390649   AA392447   AA439292   AA440310   AA539792   AA735560   AA950753   AA950902   AA950932   AA951457   AA952234   AE014298 AAF50905   AE014298 AAN09547   AI063416   AI237922   AI512012   AI512470   AI512835   AI513544   AI513609   AI515122   AI520078   AI520079   AI531631   AI531643   AY113503 AAM29508   BI167913   BI171545   BI172550   BI173546   BI173887   BI227774   BI231282   BI232896   BI233043   BI236725   BI237067   BI238044   BI238058   BI240713   BI352028   BI354780   BI356879   BI357456   BI357629   BI361998   BI364862   BI368824   BI368956   BI371498   BI374052   BI483210   BI484298   BI573522   BI573523   BI579678   BI580527   BI580913   BI623643   BI636416   CK657923   CO273981   CO275309   CO290101   CO316879   CO322335   CO332247   CO341279   EC051630   EC051631   EC053633   EC054120   EC054597   EC056160   EC060670   EC063090   EC067046   EC071731   EC082684   EC083463   EC089441   EC201506   EC239732   EC239848   EC242197   EC255946   EC259452   EL873933   EL874054   EV596231   GH944005   GH950394   GH964475   GH969272   GH973407   GH973570   Y14213 CAA74606
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O76932
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0023177    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0023177 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0023177 expression level Developmental Stage   Expression Level embryo 00-02hr    8570 embryo 02-04hr    13090 embryo 04-06hr    11358 embryo 06-08hr    10352 embryo 08-10hr    7477 embryo 10-12hr    6274 embryo 12-14hr    3363 embryo 14-16hr    3488 embryo 16-18hr    2615 embryo 18-20hr    1517 embryo 20-22hr    1934 embryo 22-24hr    1614 larva L1    1604 larva L2    1497 larva L3 12hr old    1274 larva L3 puffstage 1-2    1659 larva L3 puffstage 3-6    2383 larva L3 puffstage 7-9    2691 white prepupae new    3022 white prepupae 12hr    3598 white prepupae 24hr    3392 pupae 2d postWPP    1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day    2331 adult female 05day    3772 adult female 30day    3872 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (8570) embryo 02-04hr  (13090) embryo 04-06hr  (11358) embryo 06-08hr  (10352) embryo 08-10hr  (7477) embryo 10-12hr  (6274) embryo 12-14hr  (3363) embryo 14-16hr  (3488) embryo 16-18hr  (2615) embryo 18-20hr  (1517) embryo 20-22hr  (1934) embryo 22-24hr  (1614) larva L1  (1604) larva L2  (1497) larva L3 12hr old  (1274) larva L3 puffstage 1-2  (1659) larva L3 puffstage 3-6  (2383) larva L3 puffstage 7-9  (2691) white prepupae new  (3022) white prepupae 12hr  (3598) white prepupae 24hr  (3392) pupae 2d postWPP  (1695) pupae 3d postWPP  (958) pupae 4d postWPP  (1055) adult male 01day  (920) adult male 05day  (1112) adult male 30day  (955) adult female 01day  (2331) adult female 05day  (3772) adult female 30day  (3872) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (8570) embryo 02-04hr  (13090) embryo 04-06hr  (11358) embryo 06-08hr  (10352) embryo 08-10hr  (7477) embryo 10-12hr  (6274) embryo 12-14hr  (3363) embryo 14-16hr  (3488) embryo 16-18hr  (2615) embryo 18-20hr  (1517) embryo 20-22hr  (1934) embryo 22-24hr  (1614) larva L1  (1604) larva L2  1497 larva L3 12hr old    1274 larva L3 puffstage 1-2  (1659) larva L3 puffstage 3-6  (2383) larva L3 puffstage 7-9  (2691) white prepupae new  (3022) white prepupae 12hr  (3598) white prepupae 24hr  (3392) pupae 2d postWPP  (1695) pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day  (2331) adult female 05day  (3772) adult female 30day  (3872) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8570 embryo 02-04hr  (13090) embryo 04-06hr  (11358) embryo 06-08hr  10352 embryo 08-10hr    7477 embryo 10-12hr    6274 embryo 12-14hr    3363 embryo 14-16hr    3488 embryo 16-18hr    2615 embryo 18-20hr    1517 embryo 20-22hr    1934 embryo 22-24hr    1614 larva L1    1604 larva L2    1497 larva L3 12hr old    1274 larva L3 puffstage 1-2    1659 larva L3 puffstage 3-6    2383 larva L3 puffstage 7-9    2691 white prepupae new    3022 white prepupae 12hr    3598 white prepupae 24hr    3392 pupae 2d postWPP    1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day    2331 adult female 05day    3772 adult female 30day    3872 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8570 embryo 02-04hr    13090 embryo 04-06hr    11358 embryo 06-08hr    10352 embryo 08-10hr    7477 embryo 10-12hr    6274 embryo 12-14hr    3363 embryo 14-16hr    3488 embryo 16-18hr    2615 embryo 18-20hr    1517 embryo 20-22hr    1934 embryo 22-24hr    1614 larva L1    1604 larva L2    1497 larva L3 12hr old    1274 larva L3 puffstage 1-2    1659 larva L3 puffstage 3-6    2383 larva L3 puffstage 7-9    2691 white prepupae new    3022 white prepupae 12hr    3598 white prepupae 24hr    3392 pupae 2d postWPP    1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day    2331 adult female 05day    3772 adult female 30day    3872 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0023177 expression level Developmental Stage   Expression Level embryo 00-02hr    8570 embryo 02-04hr    13090 embryo 04-06hr    11358 embryo 06-08hr    10352 embryo 08-10hr    7477 embryo 10-12hr    6274 embryo 12-14hr    3363 embryo 14-16hr    3488 embryo 16-18hr    2615 embryo 18-20hr    1517 embryo 20-22hr    1934 embryo 22-24hr    1614 larva L1    1604 larva L2    1497 larva L3 12hr old    1274 larva L3 puffstage 1-2    1659 larva L3 puffstage 3-6    2383 larva L3 puffstage 7-9    2691 white prepupae new    3022 white prepupae 12hr    3598 white prepupae 24hr    3392 pupae 2d postWPP    1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day    2331 adult female 05day    3772 adult female 30day    3872 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (8570) embryo 02-04hr  (13090) embryo 04-06hr  (11358) embryo 06-08hr  (10352) embryo 08-10hr  (7477) embryo 10-12hr  (6274) embryo 12-14hr  (3363) embryo 14-16hr  (3488) embryo 16-18hr  (2615) embryo 18-20hr  (1517) embryo 20-22hr  (1934) embryo 22-24hr  (1614) larva L1  (1604) larva L2  (1497) larva L3 12hr old  (1274) larva L3 puffstage 1-2  (1659) larva L3 puffstage 3-6  (2383) larva L3 puffstage 7-9  (2691) white prepupae new  (3022) white prepupae 12hr  (3598) white prepupae 24hr  (3392) pupae 2d postWPP  (1695) pupae 3d postWPP  (958) pupae 4d postWPP  (1055) adult male 01day  (920) adult male 05day  (1112) adult male 30day  (955) adult female 01day  (2331) adult female 05day  (3772) adult female 30day  (3872) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (8570) embryo 02-04hr  (13090) embryo 04-06hr  (11358) embryo 06-08hr  (10352) embryo 08-10hr  (7477) embryo 10-12hr  (6274) embryo 12-14hr  (3363) embryo 14-16hr  (3488) embryo 16-18hr  (2615) embryo 18-20hr  1517 embryo 20-22hr  1934 embryo 22-24hr  1614 larva L1  1604 larva L2  1497 larva L3 12hr old    1274 larva L3 puffstage 1-2  1659 larva L3 puffstage 3-6  2383 larva L3 puffstage 7-9  (2691) white prepupae new  (3022) white prepupae 12hr  (3598) white prepupae 24hr  (3392) pupae 2d postWPP  1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day  2331 adult female 05day  (3772) adult female 30day  (3872) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8570 embryo 02-04hr  13090 embryo 04-06hr  11358 embryo 06-08hr  10352 embryo 08-10hr    7477 embryo 10-12hr    6274 embryo 12-14hr    3363 embryo 14-16hr    3488 embryo 16-18hr    2615 embryo 18-20hr    1517 embryo 20-22hr    1934 embryo 22-24hr    1614 larva L1    1604 larva L2    1497 larva L3 12hr old    1274 larva L3 puffstage 1-2    1659 larva L3 puffstage 3-6    2383 larva L3 puffstage 7-9    2691 white prepupae new    3022 white prepupae 12hr    3598 white prepupae 24hr    3392 pupae 2d postWPP    1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day    2331 adult female 05day    3772 adult female 30day    3872 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8570 embryo 02-04hr    13090 embryo 04-06hr    11358 embryo 06-08hr    10352 embryo 08-10hr    7477 embryo 10-12hr    6274 embryo 12-14hr    3363 embryo 14-16hr    3488 embryo 16-18hr    2615 embryo 18-20hr    1517 embryo 20-22hr    1934 embryo 22-24hr    1614 larva L1    1604 larva L2    1497 larva L3 12hr old    1274 larva L3 puffstage 1-2    1659 larva L3 puffstage 3-6    2383 larva L3 puffstage 7-9    2691 white prepupae new    3022 white prepupae 12hr    3598 white prepupae 24hr    3392 pupae 2d postWPP    1695 pupae 3d postWPP    958 pupae 4d postWPP    1055 adult male 01day    920 adult male 05day    1112 adult male 30day    955 adult female 01day    2331 adult female 05day    3772 adult female 30day    3872 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0023177    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0023177 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0023177 expression level Tissue   Expression Level Larval Central Nervous System    661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary    534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (661.875) Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary  534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary    534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary    534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0023177 expression level Tissue   Expression Level Larval Central Nervous System    661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary    534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary  534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary    534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    661.875 Larval Midgut    220.5 Larval Hindgut    255.5 Larval Malpighian Tubules    370.6 Larval Fat Body    147 Larval Salivary Gland    368.7 Larval Trachea    322.65 Larval Carcass    292.2 Adult Head    120.3 Adult Eye    139.075 Adult Brain    161.8 Adult Thoracic-Abdominal Ganglion    141.5 Adult Crop    211.3 Adult Midgut    151.4 Adult Hindgut    132.3 Adult Malpighian Tubules    202.7 Adult Fat Body    108.6 Adult Salivary Gland    162.1 Adult Heart    92 Adult VirginFemale Spermatheca    113.6 Adult InseminatedFemale Spermatheca    112.6 Adult Ovary    534.3 Adult Testis no informative data Adult Male Accessory Gland    127.7 Adult Carcass    94.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    120.3   NA  Eye    139.075   NA  Brain    161.8   661.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    141.5   NA  Crop    211.3   220.5  Midgut    151.4   255.5  Hindgut    132.3   370.6  Malpighian Tubules    202.7   147  Fat Body    108.6   368.7  Salivary Gland    162.1   NA  Heart    92   322.65  Trachea    NA   NA  VirginFemale Spermatheca    113.6   NA  InseminatedFemale Spermatheca    112.6   NA  Ovary    534.3   NA  Testis    no informative data   NA  Male Accessory Gland    127.7   292.2  Carcass    94.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023177 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG32505-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Pp4-19C Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 Pp4-19CGD9561 semi-lethal | embryonic stage | maternal effect | recessive Pp4-19Ccmm semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 Pp4-19CGD9561 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 Pp4-19CGD9561 visible, with Scer\GAL4pnr-MD237 Pp4-19CGD9561 Phenotype manifest in Allele centrosome | embryonic stage | maternal effect Pp4-19Ccmm embryonic/larval neuroblast | larval stage, with Scer\GAL41407 Pp4-19CGD9561 ganglion mother cell | larval stage, with Scer\GAL41407 Pp4-19CGD9561 mesothoracic tergum, with Scer\GAL4pnr-MD237 Pp4-19CGD9561 microtubule | embryonic stage | maternal effect Pp4-19Ccmm mitotic domain | maternal effect Pp4-19Ccmm
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Pp4-19C Class Mutagen Stocks Known lesion Pp4-19CG11307 P-element activity 1 -- Pp4-19Ccmm Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Pp4-19C Class Mutagen Stocks Known lesion Pp4-19CGD9561 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Pp4-19CJF02808 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Pp4-19CdsRNA.cSa in vitro construct - RNAi 0 Yes Pp4-19CScer\UAS.T:Ivir\HA in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6254 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9561} NA P{TRiP.JF02808} NA P{UAS-Pp4-19C.2xHA} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{}Pp4-19Ccmm NA insertion of mobile activating element P{EP}Pp4-19CG11307 NA
Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
microtubule-based process inferred from mutant phenotype (Helps et al., 1998) mitotic cell cycle inferred from mutant phenotype (Chen et al., 2007) M phase specific microtubule process inferred from mutant phenotype (Helps et al., 1998) neurogenesis inferred from mutant phenotype (Neumüller et al., 2011) regulation of mitotic cell cycle inferred from mutant phenotype (Helps et al., 1998)
Cellular Component
CV term Evidence References
centrosome inferred from direct assay (Helps et al., 1998) cytoplasm inferred from direct assay (Helps et al., 1998) nucleus inferred from direct assay (Helps et al., 1998)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
hydrolase activity inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 (FlyBase Curators et al., 2004-) protein serine/threonine phosphatase activity inferred from sequence or structural similarity (Chen et al., 1992) non-traceable author statement (Morrison et al., 2000)
Biological Process
CV term Evidence References
protein dephosphorylation inferred from sequence or structural similarity (Chen et al., 1992) non-traceable author statement (Morrison et al., 2000)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Pp4-19C allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 69445 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0023177 DroID - A comprehensive database of gene and protein interactions. • FBgn0023177 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45031
Orthologs
Genome-wide drosophilid orthologs	Dana\GF19488 Dere\GG17991 Dgri\GH17590 Dmoj\GI16239 Dper\GL26791 Dpse\GA16950 Dsec\GM22672 Dsim\GD15536 Dvir\GJ15931 Dwil\GK25592 Dyak\GE15348
Curated drosophilid orthologs	Dpse\GA16950   Dsim\Pp4-19C (Nurminsky et al., 2001)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004040-PA Aedes aegypti (mosquito) AGAP003779-PA Anopheles gambiae (mosquito) XP_001950610.1 Acyrthosiphon pisum (pea aphid) At5g55260.1 Arabidopsis thaliana (wall cress) 89142 Batrachochytrium dendrobatidis (chytrid fungus) 264576 Branchiostoma floridae (lancelet) 264587 Branchiostoma floridae (lancelet) XP_001897120.1 Brugia malayi (roundworm nematode) BGIBMGA013010-PA Bombyx mori (silk worm) ENSBTAP00000017178 Bos taurus (bovine) CAL0001121 Candida albicans (a form of yeast) CBP26314 Caenorhabditis briggsae (nematode) CE23041 Caenorhabditis elegans (worm) ENSCAFP00000025167 Canis familiaris (dog) Chro.10265 Cryptosporidium hominis (obligate parasite) ENSCINP00000010125 Ciona intestinalis (sea squirt) JA18583 Caenorhabditis japonica (nematode) cn01384 Cryptococcus neoformans (yeast-like fungus) cgd1_2360 Cryptosporidium parvum (protozoan parasite) CPIJ001371 Culex pipens (mosquito) ENSCPOP00000003556 Cavia porcellus (guinea pig) 132486 Chlamidomonas reinhardtii (green alga) RP01603 Caenorhabditis remanei (nematode) ENSCSAVP00000007140 Ciona savignyi (sedentary tunicate) 182833 Capitella spl (polychaete worm) DDB0185222 Dictyostelium discoideum (amoeba) DEHA2F21516g Debaryomyces Hansenii (yeast) 209708 Daphnia pulex (daphnia) ENSDARP00000020819 Danio rerio (zebra fish) ENSECAP00000019580 Equus caballus (horse) ENSGACP00000007237 Gymnopilus aculeatus (mushroom) GL50803_2053 Giardia lamblia (flagellated protozoan) 186046 Hypsipyla robusta (cedar shoot borer) ENSP00000279387 Homo sapiens (human) ISCW015013-PA Ixodes scapularis (deer tick) 196510 Lottia gigantea (owl limpet) LmjF32.3040 Leishmania major (virus) 17180 Monocosta brevicollis (choanoflagellate) ENSMODP00000019585 Monodelphis domestica (gray opossum) ENSMMUP00000001318 Macaca mulatta (rhesus monkey) ENSMUSP00000032936 Mus musculus (house mouse) 177129 Nematostella vectensis (starlet anemone) XP_001606225.1 Nasonia vitripennis (wasp) ENSOANP00000012928 Ornithorynchus anatinus (platypus) ENSORLP00000021689 Oryzias latipes (japanese killifish) LOC_Os09g11230.1 Oryza sativa (asian rice) 28049 Ostreococcus tauri (green alga) PFI1360c Plasmodium falciparum (protozoal parasite) PHUM004715-PA Pediculus humanus (human body louse) PP12881 Pristionchus pacificus (nematode) 169532 Physcomitrella patens (moss) ENSPPYP00000008189 Pongo pygmaeus (orangutan) 95996 Phytophthora ramorum (sudden oak death pathogen) 108808 Phytophthora sojae (root rot pathogen) 822885 Populus trichocarpa (black cottonwood) ENSPTRP00000053618 Pan troglodytes (chimpanzee) PVX_099825 Plasmodium vivax (protozoal parasite) ENSRNOP00000026909 Rattus norvegicus (norway rat) 4999751 Sorghum bicolor (sorghum) Smp_030710 Schistosoma mansoni (trematode parasite) SPBC26H8.05c Schizosaccharomyces pombe (fission yeast) XP_001189210.1 Strongylocentrotus purpuratus (purple sea urchin) 64151 Trichoplax adhaerens (metazoa) TA12805 Theileria annulata (apicomplexan parasite) Tc00.1047053511211.60 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017004 Tetraodon nigroviridis (green spotted pufferfish) TP02_0042 Theileria parva (parasitic protozoan) 26473 Thalassiosira pseudonana (marine diatom) ENSTRUP00000029041 Takifugu rubripes (pufferfish Takifugu) 3812.m02392 Tetrahymena thermophila (ciliate protozoa) 96098.m00077 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000044675 Xenopus tropicalis (frog) YALI0F10505g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12594 NV13328 LH18778 ISCW015013 FBgn0232928 FBgn0227551 FBgn0203118 FBgn0187202 FBgn0177542 JGI_V11_209708 FBgn0076964 FBgn0164372 FBgn0138988 FBgn0125060 FBgn0110209 FBgn0096495 CPIJ001371 BGIBMGA013010 ACYPI007135 ACYPI000564 GB12046 AGAP003779 AAEL004040 PHUM448770 GLEAN_15726
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	27726 y1 v1; P{TRiP.JF02808}attP2 26629 w* P{EP}Pp4-19CG11307/FM6, w*
VDRC	v25317 w1118; P{GD9561}v25317
Genomic Clones ( 2 )
	BACR25I22 BACR30J04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 95 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE58406
Other clones	DPiM_RE58406
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03214 GH26669 GM01843 GM17281 GM28250 LD05829 LD08675 LD09660 LD11317 LD13819 LD15241 LD18128 LD21520 LD29338 LD30864 LD31065 LD31111 LD31924 LD40035 LD40036 LD43617 LD44354 LD44901 LD45805 LD46820 RE08414 RE13348 RE15074 RE16482 RE17020 RE20729 RE25002 RE29045 RE29160 RE29327 RE32832 RE33223 RE34413 RE34429 RE37627 RE43148 RE43949 RE44155 RE46446 RE50053 RE54865 RE55022 RE61562 RE66066 RE67378 RE73745 RE74734 RE75161 RH55957 SD02807 SD02834 SD18094
Other clones	2264 11960 14630 62644 77329 161847 175696 214221.59 214283.67 275298 281338 CK01.93C.E12 CK01.124B.E7 Dmel_neb_016031_0634_0786 EC051630 EC051631 EC053633 EC054120 EC054597 EC056160 EK073050 EK112821 EK117047 EK187917 EK266079 EK302916 EP12149 IP14017 IP14117 RH09133 RP004175222 RP004246805 RP004379334 RP004382502 RP004443977 RP004503629
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0023177 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45031
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Pp4-19C CG1459 (Guan, 1999.11) Source for identity of: Pp4-19C CG1596 (Guan, 1999.11)
Source for database merge of	Source for merge of: Pp4-19C CG1596 CG1459 (Bayraktaroglu, 2000.4.17) Source for merge of: Pp4-19C CG18339 (FlyBase, 1996-)
Additional comments	Source for merge of Pp4-19C CG18339 was sequence comparison (date:001104). (FlyBase, 1996-)
Other Comments
	Pp4-19C is required for organisation of microtubules at centrosomes in Drosophila embryos. (Helps et al., 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080064 NM_167703 RefSeq (Proteins) • NP_524803 NP_728342 DDBJ / EMBL / GenBank • AAF50905 AAM29508 AAN09547 AY113503 BI371498 CAA74606 Y14213 Entrez Gene - A searchable database of RefSeq genes. • 45031 UniProtKB/TrEMBL • O76932
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Metallophosphoesterase domain (IPR004843) Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (IPR006186)
Linkouts
	BioGRID - A database of protein and genetic interactions • 69445 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0023177 DroID - A comprehensive database of gene and protein interactions. • FBgn0023177 DRSC - Results from RNAi screens. • FBgn0023177 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023177 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG32505-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0023177 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45031 InParanoid A subset of ortholog calls from InParanoid. • AAEL004040-PA Aedes aegypti (mosquito) AGAP003779-PA Anopheles gambiae (mosquito) XP_001950610.1 Acyrthosiphon pisum (pea aphid) At5g55260.1 Arabidopsis thaliana (wall cress) 89142 Batrachochytrium dendrobatidis (chytrid fungus) 264576 Branchiostoma floridae (lancelet) 264587 Branchiostoma floridae (lancelet) XP_001897120.1 Brugia malayi (roundworm nematode) BGIBMGA013010-PA Bombyx mori (silk worm) ENSBTAP00000017178 Bos taurus (bovine) CAL0001121 Candida albicans (a form of yeast) CBP26314 Caenorhabditis briggsae (nematode) CE23041 Caenorhabditis elegans (worm) ENSCAFP00000025167 Canis familiaris (dog) Chro.10265 Cryptosporidium hominis (obligate parasite) ENSCINP00000010125 Ciona intestinalis (sea squirt) JA18583 Caenorhabditis japonica (nematode) cn01384 Cryptococcus neoformans (yeast-like fungus) cgd1_2360 Cryptosporidium parvum (protozoan parasite) CPIJ001371 Culex pipens (mosquito) ENSCPOP00000003556 Cavia porcellus (guinea pig) 132486 Chlamidomonas reinhardtii (green alga) RP01603 Caenorhabditis remanei (nematode) ENSCSAVP00000007140 Ciona savignyi (sedentary tunicate) 182833 Capitella spl (polychaete worm) DDB0185222 Dictyostelium discoideum (amoeba) DEHA2F21516g Debaryomyces Hansenii (yeast) 209708 Daphnia pulex (daphnia) ENSDARP00000020819 Danio rerio (zebra fish) ENSECAP00000019580 Equus caballus (horse) ENSGACP00000007237 Gymnopilus aculeatus (mushroom) GL50803_2053 Giardia lamblia (flagellated protozoan) 186046 Hypsipyla robusta (cedar shoot borer) ENSP00000279387 Homo sapiens (human) ISCW015013-PA Ixodes scapularis (deer tick) 196510 Lottia gigantea (owl limpet) LmjF32.3040 Leishmania major (virus) 17180 Monocosta brevicollis (choanoflagellate) ENSMODP00000019585 Monodelphis domestica (gray opossum) ENSMMUP00000001318 Macaca mulatta (rhesus monkey) ENSMUSP00000032936 Mus musculus (house mouse) 177129 Nematostella vectensis (starlet anemone) XP_001606225.1 Nasonia vitripennis (wasp) ENSOANP00000012928 Ornithorynchus anatinus (platypus) ENSORLP00000021689 Oryzias latipes (japanese killifish) LOC_Os09g11230.1 Oryza sativa (asian rice) 28049 Ostreococcus tauri (green alga) PFI1360c Plasmodium falciparum (protozoal parasite) PHUM004715-PA Pediculus humanus (human body louse) PP12881 Pristionchus pacificus (nematode) 169532 Physcomitrella patens (moss) ENSPPYP00000008189 Pongo pygmaeus (orangutan) 95996 Phytophthora ramorum (sudden oak death pathogen) 108808 Phytophthora sojae (root rot pathogen) 822885 Populus trichocarpa (black cottonwood) ENSPTRP00000053618 Pan troglodytes (chimpanzee) PVX_099825 Plasmodium vivax (protozoal parasite) ENSRNOP00000026909 Rattus norvegicus (norway rat) 4999751 Sorghum bicolor (sorghum) Smp_030710 Schistosoma mansoni (trematode parasite) SPBC26H8.05c Schizosaccharomyces pombe (fission yeast) XP_001189210.1 Strongylocentrotus purpuratus (purple sea urchin) 64151 Trichoplax adhaerens (metazoa) TA12805 Theileria annulata (apicomplexan parasite) Tc00.1047053511211.60 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017004 Tetraodon nigroviridis (green spotted pufferfish) TP02_0042 Theileria parva (parasitic protozoan) 26473 Thalassiosira pseudonana (marine diatom) ENSTRUP00000029041 Takifugu rubripes (pufferfish Takifugu) 3812.m02392 Tetrahymena thermophila (ciliate protozoa) 96098.m00077 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000044675 Xenopus tropicalis (frog) YALI0F10505g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45031 modMine - Data generated by the modENCODE project. • FBgn0023177 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12594 NV13328 LH18778 ISCW015013 FBgn0232928 FBgn0227551 FBgn0203118 FBgn0187202 FBgn0177542 JGI_V11_209708 FBgn0076964 FBgn0164372 FBgn0138988 FBgn0125060 FBgn0110209 FBgn0096495 CPIJ001371 BGIBMGA013010 ACYPI007135 ACYPI000564 GB12046 AGAP003779 AAEL004040 PHUM448770 GLEAN_15726
Synonyms & Secondary IDs ( 17 )
Reported As
Symbol Synonym	CG1459 (Morrison et al., 2000, ) CG1596   CG18339 (Jia et al., 2009) CG32505 (Perkins et al., 2009) DmPpp4-19C (Cohen, 2005) PP1 (Fang et al., 2007) PP4 (Silverstein et al., 2002, de Carcer et al., 2001, Morrison et al., 2000, Zimmerman et al., 1999, Gonzalez et al., 1998, Helps et al., 1998, Cohen, 1993, Jia et al., 2009) pp4 (Cohen, 1997.7.9) PP4 19C (Cohen, 1997) Pp4-19C (Chen et al., 2007, Sousa-Nunes et al., 2009, Neumüller et al., 2011) PP4C (Sousa-Nunes et al., 2009) PPP4c (Cohen, 2005) PPX (Chen et al., 1992) PpX
Name Synonym	protein phosphatase 1 (Fang et al., 2007) Protein phosphatase 19C   Protein phosphatase X
Secondary FlyBase IDs
	FBgn0005784 FBgn0031112 FBgn0031113 FBgn0042229 FBgn0052505
References ( 42 )
Generate a list of	All references relating to this gene ( 42 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 5 ) Review  ( 6 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 ) Computer file  ( 1 ) Thesis  ( 1 ) Automatic genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 3 )
	Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Su et al., 2011, Sci. Signal. 4(180): ra43 Sequential phosphorylation of smoothened transduces graded hedgehog signaling. [FBrf0216577] Show all research papers ...
Recent reviews ( 1 )
	Sousa-Nunes and Somers, 2010, Commun. Integr. Biol. 3(1): 46--49 Phosphorylation and dephosphorylation events allow for rapid segregation of fate determinants during Drosophila neuroblast asymmetric divisions. [FBrf0211041] Show all reviews ...