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Gene Dmel\lad

General Information
Symbol	Dmel\lad	Species	D. melanogaster
Name	ladybird	Annotation symbol
Feature type	gene	FlyBase ID	FBgn0023428
Gene Model Status	Unannotated	Stock availability	None publicly available
Also Known As	lb
Genomic Location
Chromosome (arm)		Recombination map	1-27.9
Cytogenetic map		Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene ladybird is referred to in FlyBase by the symbol Dmel\lad (FBgn0023428). It is a gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process: muscle organ development. One allele is reported. The phenotypes of this allele are annotated with: eye; pigment cell. It has no annotated transcripts. Gene has not been localized to the genome sequence.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	1-27.9 (Aparisi and Najera, 1990)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11   segment border muscle | precursor   (Clark et al., 2006)
Additional Descriptive Data
Marker for
	segment border muscle | precursor
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Other Phenotypes Allele visible ladCA Phenotype manifest in Allele eye ladCA pigment cell ladCA
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of lad Class Mutagen Stocks Known lesion ladCA natural population 0 --
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of lad Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
muscle organ development traceable author statement (Dworak and Sink, 2002)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions lad allele Gene References
External Data
Linkouts
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 248509
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 248509
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	lad (Clark et al., 2006) lb (Maqbool et al., 2006, Bataillé et al., 2010)
Name Synonym	ladybird (Aparisi and Najera, 1990, Maqbool et al., 2006, Bataillé et al., 2010)
Secondary FlyBase IDs
References ( 7 )
Research paper	Bataillé et al., 2010, Dev. Cell 19(2): 317--328 Downstream of Identity Genes: Muscle-Type-Specific Regulation of the Fusion Process. [FBrf0211535] Clark et al., 2006, Dev. Biol. 294(1): 220--231 D-six4 plays a key role in patterning cell identities deriving from the Drosophila mesoderm. [FBrf0190104] Maqbool et al., 2006, PLoS ONE 1: Shaping Leg Muscles in Drosophila: Role of ladybird, a Conserved Regulator of Appendicular Myogenesis. [FBrf0193570] Aparisi and Najera, 1990, Genome 33(2): 203--208 Genetic location and biochemical characterization of eye-colour mutants from natural populations of Drosophila melanogaster. [FBrf0052044]
Review	Chen and Olson, 2004, Trends Cell Biol. 14(8): 452--460 Towards a molecular pathway for myoblast fusion in Drosophila. [FBrf0180689] Dworak and Sink, 2002, BioEssays 24(7): 591--601 Myoblast fusion in Drosophila. [FBrf0151208] Baylies et al., 1997, Cold Spring Harbor Symp. Quant. Biol. 62: 385--393 The specification of muscle in Drosophila. [FBrf0102285]