• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Tequila

General Information
Symbol	Dmel\Tequila	Species	D. melanogaster
Name	Tequila	Annotation symbol	CG4821
Feature type	protein_coding_gene	FlyBase ID	FBgn0023479
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	Teq, CG4948, graal
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	66F4-66F5	Sequence location	3L:9,067,745..9,085,231 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Tequila is referred to in FlyBase by the symbol Dmel\Tequila (CG4821, FBgn0023479). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: short-term memory; long-term memory. 10 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Chitin binding domain; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Peptidase S1; Peptidase S1, trypsin family, active site; Peptidase S1A, chymotrypsin-type; Speract/scavenger receptor; Speract/scavenger receptor-related; Trypsin-like cysteine/serine peptidase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, adult heart. Gene sequence location is 3L:9067745..9085231.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 66F4-66F5   Limits computationally determined from genome sequence between P{PZ}l(3)0162901629&P{PZ}mRpL1210534 and P{EP}Hsp26EP3336&P{EP}Hsp26EP3315
Experimentally Determined Cytological Location
Cytogenetic map Notes References 66F-67A   (determined by in situ hybridisation)   (Munier et al., 2004)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Tequila for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Gene model reviewed during 5.48 Low-frequency RNA-seq exon junction(s) not annotated. Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tequila-RA FBtr0076526  NM_140031   8608   2786 Tequila-RC FBtr0076527  NM_168315   2261   563 Tequila-RD FBtr0076525  NM_168314   4600   1450 Tequila-RE FBtr0301910  NM_001169922   7368   1603
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Tequila-PA   FBpp0076253   308.4   2786   6.43     NP_648288   AAF50319 Tequila-PC   FBpp0076254   62.0   563   7.64     NP_729452   AAF50322 Tequila-PD   FBpp0076252   160.1   1450   6.42     NP_729451   AAN11984 Tequila-PE   FBpp0291124   179.1   1603   6.31     NP_001163393   ACZ94664
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1, trypsin family, active site (IPR018114) Speract/scavenger receptor (IPR001190) Peptidase S1 (IPR001254) Peptidase S1A, chymotrypsin-type (IPR001314) Chitin binding domain (IPR002557) Trypsin-like cysteine/serine peptidase domain (IPR009003) Speract/scavenger receptor-related (IPR017448) Low-density lipoprotein (LDL) receptor class A, conserved site (IPR023415) Low-density lipoprotein (LDL) receptor class A repeat (IPR002172) MEROPS - An information resource for peptidases and the proteins that inhibit them • S01.950
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140687   AA141233   AA141237   AA141417   AA141619   AA141698   AA141745   AA141987   AA142022   AA142062   AA142063   AA142125   AA264211   AA695666   AA696090   AA802073   AE014296 AAF50319   AE014296 AAF50322   AE014296 AAN11984   AE014296 ACZ94664   AF044207 AAC02089   AI387493   AI467768   AI517310   AI531654   AI532614   AI542058   AI542319   AI542393   AI544411   AJ251802 CAB64652   AJ251803 CAB64653   AJ309005 CAC35209   AW941085   AW944265   AY052072 AAK93496   AY069235 AAL39380   AY119203 AAM51063   BG632998   BG636180   BG640013   BI213427   BI230577   BI232370   BI239344   BI239355   BI361306   BI364844   BI592783   BI635634   BI641740   BI641873   BT099591   BT132770   CK135864   CK135958   CK136030   CO153892   CO156229   CO156244   CO157112   CO176759   CO176870   CO179227   CO183902   CO190457   CO190927   CO192059   CO196145   CO196191   CO261856   CO262608   CO262614   CO262846   CO263114   CO263490   CO266285   CO266529   CO266981   CO267517   CO268181   CO270415   CO270868   CO271834   CO273139   CO273355   CO276008   CO276601   CO276918   CO277095   CO278614   CO278914   CO279906   CO280735   CO281510   CO282813   CO283373   CO283847   CO284580   CO284667   CO285073   CO285477   CO287895   CO290439   CO292108   CO292886   CO296225   CO302531   CO302565   CO303725   CO305150   CO305783   CO305819   CO306452   CO307366   CO309960   CO311454   CO311832   CO314146   CO315482   CO315500   CO316498   CO316831   CO316845   CO317857   CO318549   CO319335   CO319622   CO320245   CO320928   CO322453   CO322670   CO323471   CO323748   CO323778   CO327476   CO331098   CO331410   CO331946   CO331984   CO333255   CO333496   CO336449   CO336823   CO336887   CO338463   CO339878   CO340064   CO340329   CZ484267   EC062118   EC066375   EC074663   EC084563   EC203367   EC219309   EC220586   EC246457   EC255719   EC261202   EC261315   EC261494   EC263306   EC267333   EC267592   GH955577   GH965791   GH967669   GH979048   GH980304   GH981726
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IQB8 Q9VST9 Q9VSU0 Q9VSU2 E1JI93 Q960G6 Q8T0I5 Q9U1I3 Q8MRY3 Q9U1I2 O45029 Q9BI19
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
expression microarray Stage Tissue/Position (including subcellular localization) Reference adult stage   eye   (Xu et al., 2004)
Additional Descriptive Data
	Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads. (Xu et al., 2004)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference adult stage   neuron | subset of adult brain   (Chen et al., 2012) dorsal anterior lateral neuron of the protocerebrum   (Chen et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval/adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system, adult heart. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female    89 head, virgin 4-day female    105 head, virgin 20-day female    124 head, mated 1-day female    78 head, mated 4-day female    96 head, mated 20-day female    123 head, mated 1-day male    90 head, mated 4-day male    109 head, mated 20-day male    159 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    108 fat body, white prepupae    88 fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult    69 carcass, 4-day adult    75 carcass, 20-day adult    94 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female  (89) head, virgin 4-day female  (105) head, virgin 20-day female  (124) head, mated 1-day female  (78) head, mated 4-day female  (96) head, mated 20-day female  (123) head, mated 1-day male  (90) head, mated 4-day male  (109) head, mated 20-day male  (159) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering  (108) fat body, white prepupae  (88) fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult  (69) carcass, 4-day adult  (75) carcass, 20-day adult  (94) ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female    89 head, virgin 4-day female  105 head, virgin 20-day female  (124) head, mated 1-day female    78 head, mated 4-day female    96 head, mated 20-day female  (123) head, mated 1-day male    90 head, mated 4-day male  (109) head, mated 20-day male  (159) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering  (108) fat body, white prepupae    88 fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult    69 carcass, 4-day adult    75 carcass, 20-day adult    94 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female    89 head, virgin 4-day female    105 head, virgin 20-day female    124 head, mated 1-day female    78 head, mated 4-day female    96 head, mated 20-day female    123 head, mated 1-day male    90 head, mated 4-day male    109 head, mated 20-day male    159 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    108 fat body, white prepupae    88 fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult    69 carcass, 4-day adult    75 carcass, 20-day adult    94 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female    89 head, virgin 4-day female    105 head, virgin 20-day female    124 head, mated 1-day female    78 head, mated 4-day female    96 head, mated 20-day female    123 head, mated 1-day male    90 head, mated 4-day male    109 head, mated 20-day male    159 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    108 fat body, white prepupae    88 fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult    69 carcass, 4-day adult    75 carcass, 20-day adult    94 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female  (89) head, virgin 4-day female  (105) head, virgin 20-day female  (124) head, mated 1-day female  (78) head, mated 4-day female  (96) head, mated 20-day female  (123) head, mated 1-day male  (90) head, mated 4-day male  (109) head, mated 20-day male  (159) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering  (108) fat body, white prepupae  (88) fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult  (69) carcass, 4-day adult  (75) carcass, 20-day adult  (94) ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female    89 head, virgin 4-day female  105 head, virgin 20-day female  124 head, mated 1-day female    78 head, mated 4-day female    96 head, mated 20-day female  123 head, mated 1-day male    90 head, mated 4-day male  109 head, mated 20-day male  (159) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering  108 fat body, white prepupae    88 fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult    69 carcass, 4-day adult    75 carcass, 20-day adult    94 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    6 head, virgin 1-day female    89 head, virgin 4-day female    105 head, virgin 20-day female    124 head, mated 1-day female    78 head, mated 4-day female    96 head, mated 20-day female    123 head, mated 1-day male    90 head, mated 4-day male    109 head, mated 20-day male    159 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    108 fat body, white prepupae    88 fat body, pupae P8    18 carcass, larvae L3 wandering    4 carcass, 1-day adult    69 carcass, 4-day adult    75 carcass, 20-day adult    94 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    3 embryo 20-22hr    3 embryo 22-24hr    4 larva L1    3 larva L2    2 larva L3 12hr old    4 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    3 adult male 05day    3 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H    29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3    35 leg disc CME L1    37 wing disc CME-W2    55 wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    54 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H  (29) embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3  (35) leg disc CME L1  (37) wing disc CME-W2  (55) wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3  (28) wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5  (30) mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2  (54) ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H    29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3    35 leg disc CME L1    37 wing disc CME-W2    55 wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    54 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H    29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3    35 leg disc CME L1    37 wing disc CME-W2    55 wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    54 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H    29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3    35 leg disc CME L1    37 wing disc CME-W2    55 wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    54 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H  29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3  (35) leg disc CME L1  (37) wing disc CME-W2  (55) wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3  28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5  30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2  (54) ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H    29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3    35 leg disc CME L1    37 wing disc CME-W2    55 wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    54 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    5 Schneider line 2 Sg4    17 embryonic 1182-4H    29 embryonic GM2    1 embryonic Kc167    0 embryonic S1    3 embryonic S3    35 leg disc CME L1    37 wing disc CME-W2    55 wing disc ML-DmD8    0 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    28 wing disc ML-DmD21    3 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    3 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    54 ovary fGS/OSS    3 ovary OSC    1 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult  (28) Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult  28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    13 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    11 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    13 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    18 Ethanol 10% 3 hrs, larvae L3    17 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_14
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023479 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4821-RD;CG4821-RC;Transposon.6
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 TequilaGD4757 viable Tequilaf01792 TequilaIso1 viable, with Scer\GAL4da.G32 TequilaScer\UAS.T:SS-Drs viable, with Scer\GAL4yolk TequilaScer\UAS.T:SS-Drs Sterility Allele fertile Tequilaf01792 Other Phenotypes Allele feeding behavior defective Tequilaf01792 feeding behavior defective | RU486 conditional, with Scer\GAL4Mef2.247.Switch TequiladsRNA.Scer\UAS memory defective Tequilaf01792 memory defective, with Scer\GAL4238Y TequiladsRNA.Scer\UAS memory defective, with Scer\GAL45122 TequiladsRNA.Scer\UAS memory defective, with Scer\GAL4G0431 TequiladsRNA.Scer\UAS memory defective, with Scer\GAL4Mef2.247 TequiladsRNA.Scer\UAS memory defective | RU486 conditional, with Scer\GAL4Mef2.247.Switch TequiladsRNA.Scer\UAS Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Tequila Class Mutagen Stocks Known lesion Tequilaf01792 piggyBac transposase 2 -- TequilaMB00537 1 -- TequilaIso1 spontaneous 0 Yes
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Tequila Class Mutagen Stocks Known lesion TequilaGD4757 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes TequilaGL01328 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes TequilaHMS02486 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes TequiladsRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes TequilaNIG.4821R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes TequilaNIG.4948R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes TequilaScer\UAS.T:SS-Drs in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)29A6 (Munier et al., 2004) Df(3L)Exel6113 (Ryder, 2004.4.26) Df(3L)Rdl-2 (Munier et al., 2004)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4757} NA P{NIG.4821R} NA P{NIG.4948R} NA P{TRiP.GL01328} NA P{TRiP.HMS02486} NA P{UAS-Tequila.Drs} NA P{UAS-Tequila.RNAi} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions 412{}TequilaIso1 NA PBac{WH}Tequilaf01792 NA insertion of enhancer trap binary system Mi{ET1}TequilaMB00537 No
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
long-term memory inferred from mutant phenotype (Didelot et al., 2006, Chen et al., 2012) short-term memory inferred from direct assay (Colomb et al., 2009)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 7 terms )
Molecular Function
CV term Evidence References
chitin binding inferred from electronic annotation with InterPro:IPR002557 (FlyBase Curators et al., 2004-) scavenger receptor activity inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448 (FlyBase Curators et al., 2004-) serine-type endopeptidase activity inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Lagueux, 1999.12.30) non-traceable author statement (Lagueux, 2001.3.24, Shibata, 1998.1.20, Ross et al., 2003)
Biological Process
CV term Evidence References
chitin metabolic process inferred from electronic annotation with InterPro:IPR002557 (FlyBase Curators et al., 2004-) proteolysis inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 (FlyBase Curators et al., 2004-) non-traceable author statement (Ross et al., 2003)
Cellular Component
CV term Evidence References
extracellular region inferred from electronic annotation with InterPro:IPR002557 (FlyBase Curators et al., 2004-) membrane inferred from electronic annotation with InterPro:IPR001190, InterPro:IPR017448 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Tequila allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64448 DroID - A comprehensive database of gene and protein interactions. • FBgn0023479 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39048
Orthologs
OrthoDB Orthologs (657) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6MSDHF Dipteran inclusive ortholog search EOG6WQ19D Insect inclusive ortholog search EOG6C2G58 Arthropod inclusive ortholog search EOG6HHMH6 Metazoa inclusive ortholog search EOG6D8B01
Orthologs in Drosophila Species (EOG6MSDHF)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Tequila     Drosophila simulans   Dsim\GD14152     Drosophila sechellia   Dsec\GM25117 Y   Drosophila erecta   Dere\GG14372 Y   Drosophila yakuba   Dyak\GE23626     Drosophila yakuba   Dyak\GE23609     Drosophila yakuba   Dyak\GE20804 Y   Drosophila ananassae   Dana\GF10854 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA29318     Drosophila pseudoobscura pseudoobscura   Dpse\GA29317     Drosophila persimilis   Dper\GL15037     Drosophila persimilis   Dper\GL15038     Drosophila willistoni   Dwil\GK16219 Y   Drosophila virilis   Dvir\GJ12601     Drosophila virilis   Dvir\GJ12600     Drosophila mojavensis   Dmoj\GI16850 Y   Drosophila mojavensis   Dmoj\GI16017     Drosophila grimshawi   Dgri\GH15575 Y
Orthologs in non-Drosophila Dipterans (EOG6WQ19D)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009192   Anopheles gambiae Malaria mosquito  Agam\SCRASP1   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ007535
Orthologs in non-Dipteran Insects (EOG6C2G58)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50482   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010908   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH25564   Atta cephalotes Leafcutter ant  Acep\ACEP23976   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16920   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16081   Linepithema humile Argentine ant  Lhum\LH24788   Pogonomyrmex barbatus Red harvester ant  Pbar\CG:02549009   Solenopsis invicta Red fire ant  Sinv\SINV21926   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001573   Pediculus humanus Human body louse  Phum\PHUM244040   Pediculus humanus Human body louse  Phum\PHUM244060   Tribolium castaneum Red flour beetle  Tcas\P153
Orthologs in non-Insect Arthropods (EOG6HHMH6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_316225   Ixodes scapularis Deer tick  Isca\ISCW006069   Ixodes scapularis Deer tick  Isca\ISCW011363
Orthologs in non-Arthropod Metazoa (EOG6D8B01)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\try-1 Y Caenorhabditis elegans Nematode  Cele\clec-13 Y Caenorhabditis elegans Nematode  Cele\try-2 Y Caenorhabditis elegans Nematode  Cele\clec-13 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007781gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004011gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015410gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010232gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022423gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001229gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007052gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000646gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020206gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000362gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025983gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015387gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003554gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025128gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026709gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010895gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021457gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003966gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028804gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024487gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018671gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006538gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001588gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000926gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013342gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012039gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007893gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014095gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006731gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004101gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020597gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012410gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004500gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027379gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010227gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019239gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001172gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022149gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016107gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023677gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028445gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023706gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015937gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001901gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008409gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000675gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009989gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005926gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026234gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022567gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001004gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018737gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020822gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003127gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021124gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003384gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003964gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008504gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026917gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000492gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005154gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019928gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006539gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022150gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010240gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014993gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010991gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007782gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026849gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018949gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009354gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008514gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007718gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005798gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000740gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005848gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003778gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011222gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014859gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024151gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028669gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019826gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010226gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026941gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028233gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019370gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014829gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012159gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014992gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003526gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024408gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003963gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022085gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010062gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028382gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012390gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000984gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006531gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016174gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019479gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016952gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004160gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027556gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028497gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005556gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021789gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014994gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026637gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011146gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001110gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007899gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_002041gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005000gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001671gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026573gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003040gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003549gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005464gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022145gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013831gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005420gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004086gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007660gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016627gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018252gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022881gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027287gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021890gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010992gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009496gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007110gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011670gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006254gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019374gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021692gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018430gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022287gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015878gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009677gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009988gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000337gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001727gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003930gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005847gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022146gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012271gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001005gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022286gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020081gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011490gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015879gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005658gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021671gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004416gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028581gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009638gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010953gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003041gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000834gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015123gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003171gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001587gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026662gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025862gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019549gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010993gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022424gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020868gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001409gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001863gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026398gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021691gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014860gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011771gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023714gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016374gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022568gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015548gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027288gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028612gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003039gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001266gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020650gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016373gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007900gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027619gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022148gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010206gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019548gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008432gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007896gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016218gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021509gn Y Danio rerio Zebrafish  Drer\si:dkey-21h14.14 Y Danio rerio Zebrafish  Drer\tmprss13b Y Danio rerio Zebrafish  Drer\si:ch211-161n3.5 Y Danio rerio Zebrafish  Drer\ENSDARG00000046140 Y Danio rerio Zebrafish  Drer\zgc:123295 Y Danio rerio Zebrafish  Drer\zgc:55888 Y Danio rerio Zebrafish  Drer\ENSDARG00000076412 Y Danio rerio Zebrafish  Drer\ENSDARG00000055011 Y Danio rerio Zebrafish  Drer\si:dkey-21h14.10 Y Danio rerio Zebrafish  Drer\CABZ01065401.1 Y Danio rerio Zebrafish  Drer\zgc:100868 Y Danio rerio Zebrafish  Drer\zgc:123217 Y Danio rerio Zebrafish  Drer\ENSDARG00000063444 Y Danio rerio Zebrafish  Drer\si:ch211-235f12.5 Y Danio rerio Zebrafish  Drer\st14b Y Danio rerio Zebrafish  Drer\ENSDARG00000070897 Y Danio rerio Zebrafish  Drer\ENSDARG00000052064 Y Danio rerio Zebrafish  Drer\tmprss13a Y Danio rerio Zebrafish  Drer\ENSDARG00000087717 Y Danio rerio Zebrafish  Drer\ENSDARG00000074718 Y Danio rerio Zebrafish  Drer\ENSDARG00000060680 Y Danio rerio Zebrafish  Drer\ENSDARG00000061858 Y Danio rerio Zebrafish  Drer\tmprss9 Y Danio rerio Zebrafish  Drer\zgc:66382 Y Danio rerio Zebrafish  Drer\si:ch73-103b2.3 Y Danio rerio Zebrafish  Drer\ENSDARG00000086161 Y Danio rerio Zebrafish  Drer\tmprss12 Y Danio rerio Zebrafish  Drer\DKEY-57C15.6 Y Danio rerio Zebrafish  Drer\ENSDARG00000055014 Y Danio rerio Zebrafish  Drer\ENSDARG00000062758 Y Danio rerio Zebrafish  Drer\zgc:101788 Y Danio rerio Zebrafish  Drer\si:dkey-21h14.11 Y Danio rerio Zebrafish  Drer\zgc:165423 Y Danio rerio Zebrafish  Drer\wu:fk80d04 Y Danio rerio Zebrafish  Drer\ENSDARG00000060754 Y Danio rerio Zebrafish  Drer\si:ch1073-76a20.1 Y Danio rerio Zebrafish  Drer\tmprss4a Y Danio rerio Zebrafish  Drer\si:dkey-22n8.2 Y Danio rerio Zebrafish  Drer\si:ch211-51a6.2 Y Danio rerio Zebrafish  Drer\si:dkey-21h14.3 Y Danio rerio Zebrafish  Drer\tmprss3a Y Danio rerio Zebrafish  Drer\prss12 Y Danio rerio Zebrafish  Drer\si:dkey-14d8.22 Y Danio rerio Zebrafish  Drer\zgc:92590 Y Danio rerio Zebrafish  Drer\ENSDARG00000060592 Y Danio rerio Zebrafish  Drer\si:dkey-21h14.8 Y Danio rerio Zebrafish  Drer\ENSDARG00000052517 Y Danio rerio Zebrafish  Drer\ENSDARG00000094603 Y Danio rerio Zebrafish  Drer\st14a Y Danio rerio Zebrafish  Drer\si:dkeyp-23e4.2 Y Danio rerio Zebrafish  Drer\ENSDARG00000092989 Y Danio rerio Zebrafish  Drer\zgc:162180 Y Danio rerio Zebrafish  Drer\ENSDARG00000045837 Y Danio rerio Zebrafish  Drer\ENSDARG00000090267 Y Danio rerio Zebrafish  Drer\si:dkey-21h14.9 Y Danio rerio Zebrafish  Drer\try Y Danio rerio Zebrafish  Drer\ENSDARG00000071841 Y Danio rerio Zebrafish  Drer\ENSDARG00000045752 Y Danio rerio Zebrafish  Drer\ENSDARG00000027196 Y Danio rerio Zebrafish  Drer\tmprss3a Y Danio rerio Zebrafish  Drer\zgc:101791 Y Danio rerio Zebrafish  Drer\ENSDARG00000095253 Y Xenopus tropicalis Western clawed frog  Xtro\acr Y Xenopus tropicalis Western clawed frog  Xtro\prss12 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033327 Y Xenopus tropicalis Western clawed frog  Xtro\ovch1 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000034055 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031788 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss15 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031155 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss11a Y Xenopus tropicalis Western clawed frog  Xtro\prss36 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000007114 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000000063 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000016931 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000007152 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000005961 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000011730 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000030492 Y Xenopus tropicalis Western clawed frog  Xtro\corin Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000013549 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000013548 Y Xenopus tropicalis Western clawed frog  Xtro\klkb1 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033263 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000020735 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031419 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000003461 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000006287 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000016566 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000001929 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000004084 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000025394 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000030648 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031798 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000008030 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000034074 Y Xenopus tropicalis Western clawed frog  Xtro\prss1 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000034333 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000011752 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss13 Y Xenopus tropicalis Western clawed frog  Xtro\st14 Y Xenopus tropicalis Western clawed frog  Xtro\prss29 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000007734 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000025971 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000002231 Y Xenopus tropicalis Western clawed frog  Xtro\try10 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000025963 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000010002 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000032140 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000026148 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss9 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000008526 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033748 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000032868 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000015287 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000023763 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033132 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000022445 Y Xenopus tropicalis Western clawed frog  Xtro\f12 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033888 Y Xenopus tropicalis Western clawed frog  Xtro\klk1 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000024870 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000019305 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000031843 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000027103 Y Xenopus tropicalis Western clawed frog  Xtro\tpsg1 Y Xenopus tropicalis Western clawed frog  Xtro\prss1 Y Xenopus tropicalis Western clawed frog  Xtro\prss3 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss6 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000005939 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000006294 Y Xenopus tropicalis Western clawed frog  Xtro\prss1.2 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss5 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000006282 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000023578 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000003423 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss4 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss2 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000033999 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000001676 Y Xenopus tropicalis Western clawed frog  Xtro\tmprss11f Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000006285 Y Xenopus tropicalis Western clawed frog  Xtro\hgfac Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000004320 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000013898 Y Xenopus tropicalis Western clawed frog  Xtro\prss2 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000007129 Y Xenopus tropicalis Western clawed frog  Xtro\prss27 Y Xenopus tropicalis Western clawed frog  Xtro\xepsin Y Gallus gallus Domestic chicken  Ggal\LOC770974 Y Gallus gallus Domestic chicken  Ggal\LOC776414 Y Gallus gallus Domestic chicken  Ggal\F11 Y Gallus gallus Domestic chicken  Ggal\PRSS7 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000022426 Y Gallus gallus Domestic chicken  Ggal\TMPRSS6 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000001999 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000014720 Y Gallus gallus Domestic chicken  Ggal\TMPRSS7 Y Gallus gallus Domestic chicken  Ggal\LOC423740 Y Gallus gallus Domestic chicken  Ggal\TMPRSS3 Y Gallus gallus Domestic chicken  Ggal\LOC423942 Y Gallus gallus Domestic chicken  Ggal\LOC418421 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000014323 Y Gallus gallus Domestic chicken  Ggal\TMPRSS4 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000009103 Y Gallus gallus Domestic chicken  Ggal\LOC425590 Y Gallus gallus Domestic chicken  Ggal\ST14 Y Gallus gallus Domestic chicken  Ggal\TMPRSS2 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000001917 Y Gallus gallus Domestic chicken  Ggal\ACR Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000021986 Y Gallus gallus Domestic chicken  Ggal\TMPRSS11F Y Gallus gallus Domestic chicken  Ggal\LOC777209 Y Gallus gallus Domestic chicken  Ggal\PRSS2 Y Gallus gallus Domestic chicken  Ggal\PRSS12 Y Gallus gallus Domestic chicken  Ggal\PRSS3 Y Gallus gallus Domestic chicken  Ggal\TMPRSS9 Y Gallus gallus Domestic chicken  Ggal\HGFAC Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000022257 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000002213 Y Gallus gallus Domestic chicken  Ggal\TMPRSS5 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000010465 Y Gallus gallus Domestic chicken  Ggal\CORIN Y Gallus gallus Domestic chicken  Ggal\TMPRSS13 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000010831 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000001406 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000009118 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000022011 Y Gallus gallus Domestic chicken  Ggal\PRSS3 Y Mus musculus House mouse  Mmus\Prss36 Y Mus musculus House mouse  Mmus\Klk7 Y Mus musculus House mouse  Mmus\2210010C04Rik Y Mus musculus House mouse  Mmus\Tmprss11c Y Mus musculus House mouse  Mmus\Try4 Y Mus musculus House mouse  Mmus\Prss2 Y Mus musculus House mouse  Mmus\Prss21 Y Mus musculus House mouse  Mmus\Tmprss11e Y Mus musculus House mouse  Mmus\Prss1 Y Mus musculus House mouse  Mmus\Prss38 Y Mus musculus House mouse  Mmus\Gm10334 Y Mus musculus House mouse  Mmus\A430110N23Rik Y Mus musculus House mouse  Mmus\Try5 Y Mus musculus House mouse  Mmus\Klk8 Y Mus musculus House mouse  Mmus\Tmprss5 Y Mus musculus House mouse  Mmus\Klk12 Y Mus musculus House mouse  Mmus\Prss45 Y Mus musculus House mouse  Mmus\Klk6 Y Mus musculus House mouse  Mmus\Klk4 Y Mus musculus House mouse  Mmus\Klkb1 Y Mus musculus House mouse  Mmus\Prss28 Y Mus musculus House mouse  Mmus\Klk1b1 Y Mus musculus House mouse  Mmus\Klk1b11 Y Mus musculus House mouse  Mmus\Tmprss15 Y Mus musculus House mouse  Mmus\Cd163 Y Mus musculus House mouse  Mmus\Dmbt1 Y Mus musculus House mouse  Mmus\Prss34 Y Mus musculus House mouse  Mmus\Prss43 Y Mus musculus House mouse  Mmus\Prss30 Y Mus musculus House mouse  Mmus\Acr Y Mus musculus House mouse  Mmus\Prss8 Y Mus musculus House mouse  Mmus\Prss29 Y Mus musculus House mouse  Mmus\Tpsg1 Y Mus musculus House mouse  Mmus\ENSMUSG00000067616 Y Mus musculus House mouse  Mmus\Srcrb4d Y Mus musculus House mouse  Mmus\Prss33 Y Mus musculus House mouse  Mmus\Desc4 Y Mus musculus House mouse  Mmus\Klk1b9 Y Mus musculus House mouse  Mmus\Prss32 Y Mus musculus House mouse  Mmus\Corin Y Mus musculus House mouse  Mmus\Prss46 Y Mus musculus House mouse  Mmus\Klk5 Y Mus musculus House mouse  Mmus\Klk1 Y Mus musculus House mouse  Mmus\Tmprss9 Y Mus musculus House mouse  Mmus\Tmprss2 Y Mus musculus House mouse  Mmus\Tmprss11b Y Mus musculus House mouse  Mmus\Prss12 Y Mus musculus House mouse  Mmus\Prss42 Y Mus musculus House mouse  Mmus\Cd163l1 Y Mus musculus House mouse  Mmus\Tpsb2 Y Mus musculus House mouse  Mmus\St14 Y Mus musculus House mouse  Mmus\Klk1b4 Y Mus musculus House mouse  Mmus\Tmprss6 Y Mus musculus House mouse  Mmus\Prss48 Y Mus musculus House mouse  Mmus\Klk1b27 Y Mus musculus House mouse  Mmus\Klk14 Y Mus musculus House mouse  Mmus\Tmprss11d Y Mus musculus House mouse  Mmus\Tmprss7 Y Mus musculus House mouse  Mmus\Prss41 Y Mus musculus House mouse  Mmus\Klk1b3 Y Mus musculus House mouse  Mmus\Klk1b26 Y Mus musculus House mouse  Mmus\Tmprss4 Y Mus musculus House mouse  Mmus\Try10 Y Mus musculus House mouse  Mmus\Cd5l Y Mus musculus House mouse  Mmus\Klk1b21 Y Mus musculus House mouse  Mmus\Prss53 Y Mus musculus House mouse  Mmus\Prss27 Y Mus musculus House mouse  Mmus\F11 Y Mus musculus House mouse  Mmus\Klk9 Y Mus musculus House mouse  Mmus\Klk1b8 Y Mus musculus House mouse  Mmus\Klk1b16 Y Mus musculus House mouse  Mmus\Klk1b5 Y Mus musculus House mouse  Mmus\F12 Y Mus musculus House mouse  Mmus\Tpsab1 Y Mus musculus House mouse  Mmus\Klk10 Y Mus musculus House mouse  Mmus\1810009J06Rik Y Mus musculus House mouse  Mmus\Gm2663 Y Mus musculus House mouse  Mmus\Prss22 Y Mus musculus House mouse  Mmus\Prss52 Y Mus musculus House mouse  Mmus\Tmprss11f Y Mus musculus House mouse  Mmus\Tmprss3 Y Mus musculus House mouse  Mmus\5830411N06Rik Y Mus musculus House mouse  Mmus\Tmprss13 Y Mus musculus House mouse  Mmus\Klk13 Y Mus musculus House mouse  Mmus\Hgfac Y Mus musculus House mouse  Mmus\Tmprss11a Y Rattus norvegicus Norway rat  Rnor\Klk3 Y Rattus norvegicus Norway rat  Rnor\Klk7 Y Rattus norvegicus Norway rat  Rnor\Klk4 Y Rattus norvegicus Norway rat  Rnor\Klk1c8 Y Rattus norvegicus Norway rat  Rnor\Tmprss11d Y Rattus norvegicus Norway rat  Rnor\Dmbt1 Y Rattus norvegicus Norway rat  Rnor\Tpsab1 Y Rattus norvegicus Norway rat  Rnor\Tmprss13 Y Rattus norvegicus Norway rat  Rnor\Klk6 Y Rattus norvegicus Norway rat  Rnor\Cd5l Y Rattus norvegicus Norway rat  Rnor\Try4 Y Rattus norvegicus Norway rat  Rnor\Tmprss6 Y Rattus norvegicus Norway rat  Rnor\Prss32 Y Rattus norvegicus Norway rat  Rnor\Prss30 Y Rattus norvegicus Norway rat  Rnor\Klk11 Y Rattus norvegicus Norway rat  Rnor\Tmprss4 Y Rattus norvegicus Norway rat  Rnor\LOC100366131 Y Rattus norvegicus Norway rat  Rnor\Cd163l1 Y Rattus norvegicus Norway rat  Rnor\Prss12 Y Rattus norvegicus Norway rat  Rnor\Try10 Y Rattus norvegicus Norway rat  Rnor\Ssc5d Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000039406 Y Rattus norvegicus Norway rat  Rnor\Tpsg1 Y Rattus norvegicus Norway rat  Rnor\Gk11 Y Rattus norvegicus Norway rat  Rnor\Klkb1 Y Rattus norvegicus Norway rat  Rnor\Prss3 Y Rattus norvegicus Norway rat  Rnor\Prss1 Y Rattus norvegicus Norway rat  Rnor\Prss45 Y Rattus norvegicus Norway rat  Rnor\LOC687873 Y Rattus norvegicus Norway rat  Rnor\Klk10 Y Rattus norvegicus Norway rat  Rnor\Prss27 Y Rattus norvegicus Norway rat  Rnor\Prss29 Y Rattus norvegicus Norway rat  Rnor\Cd163 Y Rattus norvegicus Norway rat  Rnor\Acr Y Rattus norvegicus Norway rat  Rnor\LOC100365995 Y Rattus norvegicus Norway rat  Rnor\Tpsb2 Y Rattus norvegicus Norway rat  Rnor\Prss8 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000034038 Y Rattus norvegicus Norway rat  Rnor\F11 Y Rattus norvegicus Norway rat  Rnor\Srcrb4d Y Rattus norvegicus Norway rat  Rnor\Prss22 Y Rattus norvegicus Norway rat  Rnor\Klk9 Y Rattus norvegicus Norway rat  Rnor\LOC680907 Y Rattus norvegicus Norway rat  Rnor\Tmprss7 Y Rattus norvegicus Norway rat  Rnor\Klk12 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000022737 Y Rattus norvegicus Norway rat  Rnor\Tmprss3 Y Rattus norvegicus Norway rat  Rnor\Prss2 Y Rattus norvegicus Norway rat  Rnor\Klk2 Y Rattus norvegicus Norway rat  Rnor\Klk13 Y Rattus norvegicus Norway rat  Rnor\RGD1559662 Y Rattus norvegicus Norway rat  Rnor\Prss42 Y Rattus norvegicus Norway rat  Rnor\Tmprss11e Y Rattus norvegicus Norway rat  Rnor\Prss46 Y Rattus norvegicus Norway rat  Rnor\Klk9 Y Rattus norvegicus Norway rat  Rnor\Prss34 Y Rattus norvegicus Norway rat  Rnor\Tmprss11c Y Rattus norvegicus Norway rat  Rnor\Prss36 Y Rattus norvegicus Norway rat  Rnor\Tmprss11f Y Rattus norvegicus Norway rat  Rnor\Prss44 Y Rattus norvegicus Norway rat  Rnor\Tmprss2 Y Rattus norvegicus Norway rat  Rnor\St14 Y Rattus norvegicus Norway rat  Rnor\Klk1c7 Y Rattus norvegicus Norway rat  Rnor\Prss38 Y Rattus norvegicus Norway rat  Rnor\Ngfg Y Rattus norvegicus Norway rat  Rnor\Klk8 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024208 Y Rattus norvegicus Norway rat  Rnor\Tmprss5 Y Rattus norvegicus Norway rat  Rnor\Prss41 Y Rattus norvegicus Norway rat  Rnor\Prss53 Y Rattus norvegicus Norway rat  Rnor\Klk5l Y Rattus norvegicus Norway rat  Rnor\Tmprss11b Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000030492 Y Rattus norvegicus Norway rat  Rnor\Klk10 Y Rattus norvegicus Norway rat  Rnor\Tmprss15 Y Rattus norvegicus Norway rat  Rnor\Prss33 Y Rattus norvegicus Norway rat  Rnor\Corin Y Rattus norvegicus Norway rat  Rnor\Klk1c12 Y Rattus norvegicus Norway rat  Rnor\Tmprss9 Y Rattus norvegicus Norway rat  Rnor\Tmprss11g Y Rattus norvegicus Norway rat  Rnor\Klk14 Y Rattus norvegicus Norway rat  Rnor\LOC362347 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000042936 Y Rattus norvegicus Norway rat  Rnor\Hgfac Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000015139 Y Homo sapiens Human  Hsap\TPSG1 Y Homo sapiens Human  Hsap\CORIN Y Homo sapiens Human  Hsap\TPSD1 Y Homo sapiens Human  Hsap\ACR Y Homo sapiens Human  Hsap\ENSG00000260434 Y Homo sapiens Human  Hsap\KLK7 Y Homo sapiens Human  Hsap\PRSS21 Y Homo sapiens Human  Hsap\PRSS27 Y Homo sapiens Human  Hsap\KLK1 Y Homo sapiens Human  Hsap\KLK14 Y Homo sapiens Human  Hsap\CD163 Y Homo sapiens Human  Hsap\SSC5D Y Homo sapiens Human  Hsap\DMBT1 Y Homo sapiens Human  Hsap\PRSS46 Y Homo sapiens Human  Hsap\KLK10 Y Homo sapiens Human  Hsap\PRSS3 Y Homo sapiens Human  Hsap\PRSS33 Y Homo sapiens Human  Hsap\TMPRSS3 Y Homo sapiens Human  Hsap\ENSG00000164344 Y Homo sapiens Human  Hsap\PRSS48 Y Homo sapiens Human  Hsap\PRSS42 Y Homo sapiens Human  Hsap\TMPRSS11F Y Homo sapiens Human  Hsap\KLK13 Y Homo sapiens Human  Hsap\TMPRSS11D Y Homo sapiens Human  Hsap\ENSG00000129455 Y Homo sapiens Human  Hsap\PRSS36 Y Homo sapiens Human  Hsap\ENSG00000187054 Y Homo sapiens Human  Hsap\KLK3 Y Homo sapiens Human  Hsap\KLK12 Y Homo sapiens Human  Hsap\CD5L Y Homo sapiens Human  Hsap\CD163L1 Y Homo sapiens Human  Hsap\F12 Y Homo sapiens Human  Hsap\KLK5 Y Homo sapiens Human  Hsap\PRSS38 Y Homo sapiens Human  Hsap\TMPRSS2 Y Homo sapiens Human  Hsap\ENSG00000137648 Y Homo sapiens Human  Hsap\KLK9 Y Homo sapiens Human  Hsap\PRSS22 Y Homo sapiens Human  Hsap\F11 Y Homo sapiens Human  Hsap\ENSG00000262739 Y Homo sapiens Human  Hsap\PRSS12 Y Homo sapiens Human  Hsap\TMPRSS9 Y Homo sapiens Human  Hsap\KLK2 Y Homo sapiens Human  Hsap\HGFAC Y Homo sapiens Human  Hsap\PRSS45 Y Homo sapiens Human  Hsap\ENSG00000257652 Y Homo sapiens Human  Hsap\TMPRSS7 Y Homo sapiens Human  Hsap\TMPRSS15 Y Homo sapiens Human  Hsap\SRCRB4D Y Homo sapiens Human  Hsap\KLK11 Y Homo sapiens Human  Hsap\PRSS1 Y Homo sapiens Human  Hsap\TPSAB1 Y Homo sapiens Human  Hsap\TMPRSS5 Y Homo sapiens Human  Hsap\TMPRSS11E Y Homo sapiens Human  Hsap\ENSG00000187950 Y Homo sapiens Human  Hsap\KLK4 Y Homo sapiens Human  Hsap\TMPRSS13 Y Homo sapiens Human  Hsap\PRSS53 Y Homo sapiens Human  Hsap\TMPRSS6 Y Homo sapiens Human  Hsap\ENSG00000214279 Y Homo sapiens Human  Hsap\TMPRSS11B Y Homo sapiens Human  Hsap\ST14 Y Homo sapiens Human  Hsap\PRSS8 Y
Human Orthologs (63)
Gene OMIM HGNC Hsap\TPSG1     Hsap\CORIN     Hsap\TPSD1     Hsap\ACR     Hsap\ENSG00000260434     Hsap\KLK7     Hsap\PRSS21     Hsap\PRSS27     Hsap\KLK1     Hsap\KLK14     Hsap\CD163     Hsap\SSC5D     Hsap\DMBT1     Hsap\PRSS46     Hsap\KLK10     Hsap\PRSS3     Hsap\PRSS33     Hsap\TMPRSS3     Hsap\ENSG00000164344     Hsap\PRSS48     Hsap\PRSS42     Hsap\TMPRSS11F     Hsap\KLK13     Hsap\TMPRSS11D     Hsap\ENSG00000129455     Hsap\PRSS36     Hsap\ENSG00000187054     Hsap\KLK3     Hsap\KLK12     Hsap\CD5L     Hsap\CD163L1     Hsap\F12     Hsap\KLK5     Hsap\PRSS38     Hsap\TMPRSS2     Hsap\ENSG00000137648     Hsap\KLK9     Hsap\PRSS22     Hsap\F11     Hsap\ENSG00000262739     Hsap\PRSS12     Hsap\TMPRSS9     Hsap\KLK2     Hsap\HGFAC     Hsap\PRSS45     Hsap\ENSG00000257652     Hsap\TMPRSS7     Hsap\TMPRSS15     Hsap\SRCRB4D     Hsap\KLK11     Hsap\PRSS1     Hsap\TPSAB1     Hsap\TMPRSS5     Hsap\TMPRSS11E     Hsap\ENSG00000187950     Hsap\KLK4     Hsap\TMPRSS13     Hsap\PRSS53     Hsap\TMPRSS6     Hsap\ENSG00000214279     Hsap\TMPRSS11B     Hsap\ST14     Hsap\PRSS8
AAA Orthologs (7) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM25117 Drosophila erecta Dere\GG14372 Drosophila yakuba Dyak\GE20804 Drosophila ananassae Dana\GF10854 Drosophila willistoni Dwil\GK16219 Drosophila mojavensis Dmoj\GI16850 Drosophila grimshawi Dgri\GH15575
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	18473 w1118; PBac{WH}Tequilaf01792 41896 y1 v1; P{TRiP.GL01328}attP40 22832 y1 w67c23; Mi{ET1}TequilaMB00537 42650 y1 sc* v1; P{TRiP.HMS02486}attP2
Harvard	- PBac{WH}Tequilaf01792
VDRC	v15362 w1118 P{GD4757}v15362 v45232 w1118; P{GD4757}v45232
Genomic Clones ( 1 )
	BACR03E24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 152 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH28017 LP04489 RE18826 SD02860 SD13780
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM03224 GM03815 GM05045 LD07807 RE14280 RE28425 RE35814 RE35826 RE45468 RE50035 RH10564 SD02313 SD04181 SD08122 SD08607 SD08690 SD10309 SD10954 SD21404 SD25324 SD25524
Other clones	1822 37029 45364 62333 64441 144939 158436 214481.76 522922 527274 527293 533977 561881 561945 CK01.101D.F9 CK00198 CK00217 CK00276 CK00290 CK00399 CK01418 CK01435 CK01710 CK02129 CK02242 CK02431 EC26634 EC32742 EK001146 EK001816 EK048241 EK050126 EK050902 EK051431 EK058816 EK067046 EK074010 EK080748 EK085921 EK085928 EK086522 EK087521 EK088646 EK090460 EK098818 EK100806 EK104826 EK109812 EK110627 EK119406 EK121537 EK122408 EK122935 EK130555 EK132303 EK136345 EK145861 EK146701 EK148060 EK150642 EK154733 EK157335 EK161258 EK162951 EK164553 EK166337 EK166523 EK168134 EK169053 EK184348 EK184436 EK188154 EK188619 EK190542 EK191342 EK191430 EK199217 EK201143 EK213058 EK220032 EK224614 EK226934 EK235206 EK242629 EK247539 EK249423 EK249507 EK251054 EK254438 EK261620 EK261662 EK265103 EK266014 EK266032 EK269517 EK272734 EK277654 EK279364 EK283053 EK288824 EK298018 EK299637 EK302060 EK302235 EK306316 EK307114 EN03033 EN07618 EN07635 EN09948 EN12547 EN13319 EN13429 EN16847 EP07313 EP09547 EP09949 EP10433 GH18038 RP004094458 RP004228593 RP004242485 RP004254053 RP004464164 RP004487837 SD17036
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0023479 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39048
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Tequila anon-EST:ParkEST161 (Bayraktaroglu, 2000.11.2) Source for merge of: Tequila BEST:CK00198 BEST:GH18038 (Rana, 2004.7.8) Source for merge of: Tequila graal CG18403 CG4948 (Bayraktaroglu, 2000.8.7)
Additional comments	Annotations CG4821, CG4948 and CG18153 merged as CG4821 (which corresponds to Tequila) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Release 1 annotation CG18403 corresponds to part of the r3.2 annotation for Tequila (CG4821). (FlyBase, 1996-)
Other Comments
	One of 42 Drosophila genes identified as being most likely to reveal molecular and cellular mechanisms of nervous system development or plasticity relevant to human Mental Retardation disorders. (Inlow and Restifo, 2004) Identification: cDNA screen for secreted and transmembrane proteins expressed during embryogenesis. (Kopczynski et al., 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140031 NM_168314 NM_168315 NM_001169922 RefSeq (Proteins) • NP_648288 NP_729451 NP_729452 NP_001163393 DDBJ / EMBL / GenBank • AA142062 AA142063 AAC02089 AAF50319 AAF50321 AAF50322 AAK93496 AAL39380 AAM51063 AAN11984 ACZ94664 AF044207 AI387493 AI467768 AI517310 AI531654 AJ251802 AJ251803 AJ309005 AW941085 AW944265 AY052072 AY069235 AY119203 BG632998 BG636180 BI635634 CAB64652 CAB64653 CAC35209 CZ484267 Entrez Gene - A searchable database of RefSeq genes. • 39048 UniProtKB/TrEMBL • E1JI93 O45029 Q8IQB8 Q8MRY3 Q8T0I5 Q9BI19 Q9U1I2 Q9U1I3 Q9VST9 Q9VSU0 Q9VSU2 Q960G6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1, trypsin family, active site (IPR018114) Speract/scavenger receptor (IPR001190) Peptidase S1 (IPR001254) Peptidase S1A, chymotrypsin-type (IPR001314) Chitin binding domain (IPR002557) Trypsin-like cysteine/serine peptidase domain (IPR009003) Speract/scavenger receptor-related (IPR017448) Low-density lipoprotein (LDL) receptor class A, conserved site (IPR023415) Low-density lipoprotein (LDL) receptor class A repeat (IPR002172) MEROPS - An information resource for peptidases and the proteins that inhibit them • S01.950
Linkouts
	BioGRID - A database of protein and genetic interactions • 64448 DroID - A comprehensive database of gene and protein interactions. • FBgn0023479 DRSC - Results from RNAi screens. • FBgn0023479 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023479 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4821-RD;CG4821-RC;Transposon.6 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0023479 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39048 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39048 modMine - Data generated by the modENCODE project. • FBgn0023479
Synonyms & Secondary IDs ( 14 )
Reported As
Symbol Synonym	anon-EST:ParkEST161   BEST:CK00198   BEST:GH18038   CG4821 (Hollien and Weissman, 2006, Wertheim et al., 2005, Ni et al., 2010.12.1) CG4948 (Munier et al., 2004, Xu et al., 2004, Yang et al., 2005) CG18153 (Luschnig, 2003.12.17, ) CG18403 (Munier et al., 2004, ) CK00198 (Kopczynski et al., 1998) graal (Munier et al., 2004, Lagueux, 2001.3.24, Lagueux, 1999.12.30, ) SP72 (Ross et al., 2003) Teq (Didelot et al., 2006, Didelot, 2006, Sonderegger and Patthy, 2007, Preat et al., 2007, Ashton-Beaucage et al., 2010) teq (Didelot et al., 2006, Colomb et al., 2009) Tequila (Hollien and Weissman, 2006, Hollien and Weissman, 2006, Chen et al., 2012, Kelleher and Pennington, 2009, Lipatov et al., 2005, Mastushita-Sakai et al., 2010, Shah et al., 2008, Rollmann et al., 2006, Wertheim et al., 2011, Lai et al., 2007, Witsell et al., 2009, Wertheim et al., 2005, Fernández-Ayala et al., 2010, Remolina et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Majumdar et al., 2012)
Name Synonym	CG4948 (Yang et al., 2005) Tequila (Didelot et al., 2006, Sonderegger and Patthy, 2007, Preat et al., 2007, Guan et al., 2011, Allen and Spradling, 2008, Lipatov et al., 2005, Shah et al., 2008, Rollmann et al., 2006, Lai et al., 2007, Ashton-Beaucage et al., 2010) tequila (Krashes and Waddell, 2008, Colomb et al., 2009)
Secondary FlyBase IDs
	FBgn0025714 FBgn0026292 FBgn0029083 FBgn0035961 FBgn0035962 FBgn0035963 FBgn0043819
References ( 65 )
Generate a list of	All references relating to this gene ( 65 )
List References by type	Research paper  ( 34 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 13 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 4 ) Note  ( 1 ) Stock list  ( 1 ) Curated genome annotation  ( 3 )
Recent research papers ( 5 )
	Chen et al., 2012, Science 335(6069): 678--685 Visualizing long-term memory formation in two neurons of the Drosophila brain. [FBrf0217453] Majumdar et al., 2012, Cell 148(3): 515--529 Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory. [FBrf0217407] Remolina et al., 2012, Evolution 66(11): 3390--3403 GENOMIC BASIS OF AGING AND LIFE-HISTORY EVOLUTION IN DROSOPHILA MELANOGASTER. [FBrf0219782] Guan et al., 2011, Learn. Mem. 18(4): 191--206 Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. [FBrf0213277] Wertheim et al., 2011, Mol. Ecol. 20(5): 932--949 Functional genomics of the evolution of increased resistance to parasitism in Drosophila. [FBrf0213049] Show all research papers ...