FB2020_06, released Dec 22, 2020

Gene: Dmel\Pph13

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General Information
Symbol
Dmel\Pph13
Species
D. melanogaster
Name
PvuII-PstI homology 13
Annotation Symbol
CG2819
Feature Type
protein_coding_gene
FlyBase ID
FBgn0023489
Gene Model Status
Current
Stock Availability
9 publicly available
Gene Snapshot
PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. [Date last reviewed: 2019-03-14]
Other Summaries
Also Known As

Munster, hazy, Mu

Key Links
Genomic Location
Cytogenetic map
21E2-21E2
Sequence location
2L:577,486..579,549 [+]
Recombination map

2-1.5

RefSeq locus
NT_033779 REGION:577486..579549
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (13 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables DNA-binding transcription activator activity, RNA polymerase II-specific
inferred from direct assay
(Mishra et al., 2010, Zelhof et al., 2003)
enables protein homodimerization activity
inferred from direct assay
(Mishra et al., 2010)
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding
inferred from direct assay
(Mishra et al., 2010, Zelhof et al., 2003)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables DNA-binding transcription factor activity, RNA polymerase II-specific
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(assigned by GO_Central )
(Gaudet et al., 2011)
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (7 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
involved_in compound eye photoreceptor development
inferred from mutant phenotype
(Mishra et al., 2010)
involved_in ocellus photoreceptor cell development
inferred from genetic interaction with FLYBASE:oc; FB:FBgn0004102
(Mishra et al., 2010)
involved_in photoreceptor cell development
inferred from mutant phenotype
(Bernardo-Garcia et al., 2017)
involved_in positive regulation of transcription by RNA polymerase II
inferred from direct assay
(Mishra et al., 2010, Zelhof et al., 2003)
involved_in positive regulation of transcription, DNA-templated
inferred from direct assay
(Mishra et al., 2010)
involved_in rhabdomere development
inferred from mutant phenotype
(Mishra et al., 2010, Zelhof et al., 2003)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Zelhof et al., 2003)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in chromatin
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
PAIRED-LIKE HOMEOBOX TRANSCRIPTION FACTORS -
Paired-like (PRD-like) homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. PRD-like transcription factors lack a paired domain but possess a homeodomain characteristic of the paired homeobox transcription factors. Some members also possess an Engrailed Homology 1 (EH1) and/or an OAR motif near the C-terminus. (Adapted from FBrf0232555 and FBrf0106517).
Summary (Interactive Fly)

homeodomain transcription expressed in the developing eye - required for rhabdomere morphogenesis and proper detection of light

Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Pph13 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.42

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Pph13-RA
FBtr0078070
NM_057982
1880
357
Additional Transcript Data and Comments
Reported size (kB)

1.9 (longest cDNA)

(Goriely et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Pph13-PA
FBpp0077730
39.3
357
4.89
NP_477330
AAF51474
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

357 (aa)

(Goriely et al., 1999)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pph13 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
expression microarray
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
eye
(Xu et al., 2004)
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
eye
(Goriely et al., 1999)
medulla
(Goriely et al., 1999)
photoreceptor cell of retina
(Goriely et al., 1999)
lamina
(Goriely et al., 1999)
embryonic stage 17
Bolwig organ | presumptive
(Goriely et al., 1999)
embryonic stage 12 -- 17
Bolwig organ | precursor
(Goriely et al., 1999)
embryonic stage 11 -- 12
Bolwig organ primordium

Comment: reported as larval eye primordium

(Fisher et al., 2012)
embryonic stage 13 -- 16
Bolwig organ
(Fisher et al., 2012)
Additional Descriptive Data

Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.

(Xu et al., 2004)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 16
Bolwig organ
(Zelhof et al., 2003)
pupal stage P7 -- adult stage
photoreceptor cell
(Zelhof et al., 2003)
embryonic stage 15
Bolwig organ primordium
(Mishra et al., 2013)
third instar larval stage
Bolwig organ primordium
(Mishra et al., 2013)
photoreceptor cell
(Mishra et al., 2016)
adult stage
eyelet
(Mishra et al., 2013)
ocellus retinula cell
(Mishra et al., 2016)
Additional Descriptive Data

Pph13 protein is expressed at late embryonic stages in the cells of the Bolwig organ, and in no other embryonic tissues. There is no expression in the imaginal discs, including eye discs, during larval stages. Pupal expression begins at 36 hours APF; during pupal development, Pph13 protein is expressed in all eight photoreceptor cells. This pattern is maintained in the adult eye.

(Zelhof et al., 2003)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Zelhof et al., 2003)
Expression Deduced from Reporters
Reporter: P{Pph13-GAL4.1.6}
Stage
Tissue/Position (including subcellular localization)
Reference
pharate adult stage P14
photoreceptor cell
(Nie et al., 2012)
Reporter: P{Pph13-GFP.wt}
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
photoreceptor cell
(Bernardo-Garcia et al., 2016)
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Pph13 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 2 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Pph13
Transgenic constructs containing regulatory region of Pph13
Deletions and Duplications ( 13 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (14)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ARX
5 of 15
Yes
No
Hsap\ALX1
4 of 15
No
No
Hsap\ALX3
3 of 15
No
No
Hsap\ALX4
2 of 15
No
No
Hsap\DRGX
2 of 15
No
No
Hsap\ESX1
2 of 15
No
Yes
Hsap\ISX
1 of 15
No
No
Hsap\PHOX2A
1 of 15
No
No
Hsap\PHOX2B
1 of 15
No
No
Hsap\RAX2
1 of 15
No
No
Hsap\RAX
1 of 15
No
No
1  
Hsap\RHOXF1
1 of 15
No
Yes
Hsap\RHOXF2B
1 of 15
No
No
Hsap\RHOXF2
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (16)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Arx
5 of 15
Yes
No
Mmus\Alx1
3 of 15
No
Yes
Mmus\Alx3
3 of 15
No
Yes
Mmus\Esx1
2 of 15
No
Yes
Mmus\Prrxl1
2 of 15
No
No
Mmus\Alx4
1 of 15
No
No
Mmus\Isx
1 of 15
No
No
Mmus\Phox2a
1 of 15
No
No
Mmus\Phox2b
1 of 15
No
No
Mmus\Ppp1r21
1 of 15
No
No
Mmus\Rax
1 of 15
No
No
Mmus\Rhox5
1 of 15
No
Yes
Mmus\Rhox10
1 of 15
No
Yes
Mmus\Rhox11
1 of 15
No
Yes
Mmus\Rhox12
1 of 15
No
Yes
Mmus\Rhox13
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (14)
Rnor\Alx1
3 of 13
Yes
No
Rnor\Arx
3 of 13
Yes
No
Rnor\Alx3
2 of 13
No
Yes
Rnor\Alx4
2 of 13
No
No
Rnor\Drgx
2 of 13
No
No
Rnor\Arrb1
1 of 13
No
No
Rnor\Esx1
1 of 13
No
Yes
Rnor\Isx
1 of 13
No
Yes
Rnor\Phox2a
1 of 13
No
No
Rnor\Phox2b
1 of 13
No
No
Rnor\Rhox10
1 of 13
No
Yes
Rnor\Rhox11
1 of 13
No
No
Rnor\Rhox12
1 of 13
No
Yes
Rnor\Rhox13
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (11)
Xtro\alx1
3 of 12
Yes
Yes
Xtro\arx
3 of 12
Yes
Yes
Xtro\drgx
2 of 12
No
No
Xtro\alx4
1 of 12
No
No
Xtro\bix1.1
1 of 12
No
Yes
Xtro\LOC100491743
1 of 12
No
Yes
Xtro\mixer
1 of 12
No
No
Xtro\mixl1
1 of 12
No
Yes
Xtro\rax2
1 of 12
No
Yes
Xtro\rax
1 of 12
No
No
Xtro\sebox
1 of 12
No
Yes
Danio rerio (Zebrafish) (18)
Drer\arxa
4 of 15
Yes
No
Drer\alx1
3 of 15
No
Yes
Drer\alx3
3 of 15
No
Yes
Drer\alx4a
2 of 15
No
No
Drer\alx4b
2 of 15
No
Yes
Drer\arxb
2 of 15
No
No
Drer\drgx
2 of 15
No
No
Drer\phox2a
2 of 15
No
No
Drer\phox2bb
2 of 15
No
No
Drer\dharma
1 of 15
No
No
Drer\mxtx1
1 of 15
No
Yes
Drer\phox2ba
1 of 15
No
No
Drer\prop1
1 of 15
No
Yes
Drer\rx1
1 of 15
No
No
Drer\rx2
1 of 15
No
No
Drer\rx3
1 of 15
No
No
Drer\sebox
1 of 15
No
Yes
Drer\si:dkey-43p13.5
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (7)
Cele\alr-1
4 of 15
Yes
No
Cele\ceh-8
2 of 15
No
No
Cele\ceh-54
2 of 15
No
No
Cele\ceh-17
1 of 15
No
No
Cele\ceh-45
1 of 15
No
No
Cele\ceh-53
1 of 15
No
No
Cele\unc-42
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (1)
Atha\HB-7
1 of 9
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\yox1
1 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190ENP )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00000067
Drosophila simulans
Dsim\GD23036
Drosophila sechellia
Dsec\GM16755
Drosophila erecta
Dere\GG24732
Drosophila yakuba
Dyak\GE16946
Drosophila ananassae
Dana\GF15026
Drosophila pseudoobscura pseudoobscura
Dpse\GA15474
Drosophila persimilis
Dper\GL18888
Drosophila willistoni
Dwil\GK24418
Drosophila virilis
Dvir\GJ17788
Drosophila mojavensis
Dmoj\GI21809
Drosophila grimshawi
Dgri\GH11236
Drosophila grimshawi
Dgri\GH11036
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091507VO )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17015817
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_12371
Mayetiola destructor
Hessian fly
Mdes\Mdes018102
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL013809
Anopheles gambiae
Malaria mosquito
Agam\AGAP000858
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ003197
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W08CG )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA004601
Danaus plexippus
Monarch butterfly
Dple\DPOGS216193-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS216194-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL015847
Apis florea
Little honeybee
Aflo\2277714228
Apis mellifera
Western honey bee
Amel\LOC725502
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP19675
Bombus terrestris
Buff-tailed bumblebee
Bter\15206158
Linepithema humile
Argentine ant
Lhum\LH24644
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001162
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG020673
Tribolium castaneum
Red flour beetle
Tcas\Mu
Pediculus humanus
Human body louse
Phum\PHUM171660
Rhodnius prolixus
Kissing bug
Rpro\RPRC009706
Cimex lectularius
Bed bug
Clec\CLEC002225
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI45604
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0880 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_8835
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (26)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
al
5 of 10
CG9876
2 of 10
CG11294
2 of 10
CG32532
2 of 10
Drgx
2 of 10
Gsc
2 of 10
hbn
2 of 10
repo
2 of 10
Rx
2 of 10
Vsx2
2 of 10
eve
1 of 10
ey
1 of 10
eyg
1 of 10
gsb
1 of 10
gsb-n
1 of 10
oc
1 of 10
otp
1 of 10
PHDP
1 of 10
Poxm
1 of 10
Poxn
1 of 10
prd
1 of 10
Ptx1
1 of 10
sv
1 of 10
toe
1 of 10
unc-4
1 of 10
Vsx1
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 4 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    ARX; aristaless related homeobox
    5 of 15
    300382
    ALX1; ALX homeobox 1
    4 of 15
    601527
      ALX3; ALX homeobox 3
      3 of 15
      606014
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Pph13
        enhanceable
        oc
        (Mishra et al., 2010)
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        gl
        suppressible
        Pph13
        (Liang et al., 2016)
        External Data
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map

        2-1.5

        Cytogenetic map
        21E2-21E2
        Sequence location
        2L:577,486..579,549 [+]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        21E2-21E2
        Limits computationally determined from genome sequence between P{lacW}l(2)k09610k09610&P{lacW}Sk09538a and P{PZ}l(2)1068510685&P{lacW}Tango14k00619
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        21C-21D
        (Goriely, 1999.4.29)
        21C5-21C6
        (Goriely et al., 1999)
        21C5-21C6
        (determined by in situ hybridisation)
        (Goriely, 1996.8.22)
        21C1-21D2
        (Schneitz and Noll, 1990)
        Gsc and Pph13 map within 10kb of each other. The cytological location has been previously, and erroneously, reported as 60C (FBrf0065373).
        (Goriely, 1996.8.22)
        Experimentally Determined Recombination Data
        Location

        2-1.5

        (FlyBase, 2016)

        2-0.2

        (Comeron et al., 2012)

        2-

        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (9)
        Genomic Clones (10)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (5)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Zelhof et al., 2003)
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of

        Source for identity of: Pph13 CG2819

        (Guan, 1999.11)
        Source for database merge of
        Additional comments

        Pph13 and Gsc are closely linked.

        (Schneitz and Noll, 1990)
        Other Comments

        The sequence used to clone Gsc as reported in FBrf0087230 was '60Mun2', not Pph13 (60Mun1).

        (Noll and McGinnis, 1998.2.19)

        Pph13 is a prd-type homeobox gene.

        (Schneitz and Noll, 1990)

        An incompletely characterised homeodomain sequence.

        Origin and Etymology
        Discoverer
        Etymology

        The gene is named "hazy" based on the malformed rhabdomeres seen in the mutant and the inability of the mutant to detect light.

        (Zelhof et al., 2003)
        Identification
        External Crossreferences and Linkouts ( 35 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        modMine - A data warehouse for the modENCODE project
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        FlyMine - An integrated database for Drosophila genomics
        Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
        Synonyms and Secondary IDs (9)
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        References (67)