EG:86E4.5 , dOCRL
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ocrl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ocrl in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Ocrl CG3573
dsRNA made from templates generated with primers directed against CG3573 that is transfected into S2 treated with Listeria monocytogenes reveals CG3573 to be involved in Listeria monocytogenes entry, intracellular growth, and vacuolar escape. Treatment with Sbf dsRNA leads to an approximate 50% decrease in bacterial entry, and an approximate 35% decrease in vacuolar escape.
One of 42 Drosophila genes identified as being most likely to reveal molecular and cellular mechanisms of nervous system development or plasticity relevant to human Mental Retardation disorders.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Named after one of its two human orthologs, oculocerebrorenal syndrome of Lowe 1.