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Gene Dmel\Or2a

General Information
Symbol	Dmel\Or2a	Species	D. melanogaster
Name	Odorant receptor 2a	Annotation symbol	CG3206
Feature type	protein_coding_gene	FlyBase ID	FBgn0023523
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	DOR62, EG:30B8.7, AN4
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	2F2-2F2	Sequence location	X:2,140,264..2,141,609 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Odorant receptor 2a is referred to in FlyBase by the symbol Dmel\Or2a (CG3206, FBgn0023523). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: olfactory receptor activity. There is experimental evidence that it is involved in the biological process: sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Olfactory receptor, Drosophila. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of extremely low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1630077_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Or2a. Gene sequence location is X:2140264..2141609.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 2F2-2F2   Limits computationally determined from genome sequence between P{EP}EP1460&P{EP}CG2924EP1596 and P{EP}EP1606
Experimentally Determined Cytological Location
Cytogenetic map Notes References 2F-2F     (Vosshall, 1999.2.9)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Or2a for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Or2a-RA FBtr0070397  NM_080307   1276   397
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Or2a-PA   FBpp0070381   45.9   397   8.28     NP_525046   AAF45759
Additional Polypeptide Data & Comments
Reported size (kDa)	393 (aa) (Gao and Chess, 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Olfactory receptor, Drosophila (IPR004117)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF45759   AF127921 AAD26356   AL009195 CAA15703   BD268279   BT122047   BT133350
UniProtKB/Swiss-Prot	O46077
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference adult stage   sensory neuron of third segment of antenna   (Vosshall et al., 1999) adult olfactory receptor neuron Or2a   (Couto et al., 2005)
Additional Descriptive Data
	Or2a (Or2F.1 not on gene report as synonym. should be) is expressed in about 20 cells at the distal edge of the antenna. (Vosshall et al., 1999)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
integral to membrane inferred from direct assay (Hallem and Carlson, 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.075 Larval Midgut    0.9 Larval Hindgut    1.2 Larval Malpighian Tubules    1.6 Larval Fat Body    1.4 Larval Salivary Gland    4 Larval Trachea    1.35 Larval Carcass    0.925 Adult Head    1.1 Adult Eye    1.175 Adult Brain    0.9 Adult Thoracic-Abdominal Ganglion    1.6 Adult Crop    1.8 Adult Midgut    1.7 Adult Hindgut    1.1 Adult Malpighian Tubules    2.7 Adult Fat Body    1.2 Adult Salivary Gland    5.7 Adult Heart    1.125 Adult VirginFemale Spermatheca    4.6 Adult InseminatedFemale Spermatheca    2.6 Adult Ovary    0.7 Adult Testis    2.4 Adult Male Accessory Gland    1 Adult Carcass    2.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1.1   NA  Eye    1.175   NA  Brain    0.9   1.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1.6   NA  Crop    1.8   0.9  Midgut    1.7   1.2  Hindgut    1.1   1.6  Malpighian Tubules    2.7   1.4  Fat Body    1.2   4  Salivary Gland    5.7   NA  Heart    1.125   1.35  Trachea    NA   NA  VirginFemale Spermatheca    4.6   NA  InseminatedFemale Spermatheca    2.6   NA  Ovary    0.7   NA  Testis    2.4   NA  Male Accessory Gland    1   0.925  Carcass    2.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of extremely low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    1 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    1 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    1 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    0 Paraquat 10 mM 48 hrs, 4-day adult    0 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_07
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023523 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3206-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Or2aGD711 Other Phenotypes Allele smell perception defective, with Scer\GAL4Or22a.8197 Or2aScer\UAS.T:Hsap\MYC Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Or2a Class Mutagen Stocks Known lesion Or2aCTG-480.3 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Or2a Class Mutagen Stocks Known lesion Or2aGD711 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Or2aJF02442 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Or2aKK106583 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Or2aScer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD711} NA P{KK106583} NA P{TRiP.JF02442} NA P{UAS-Or2a.MYC} NA GAL4 construct P{Or2a-GAL4.C} No P{Or2a-GAL4.F} No
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{UASp-CTG.480}Or2aCTG-480.3 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
olfactory receptor activity inferred from direct assay (Hallem and Carlson, 2006)
Biological Process
CV term Evidence References
detection of chemical stimulus involved in sensory perception of smell inferred from direct assay (Hallem and Carlson, 2006) sensory perception of smell inferred from expression pattern (Vosshall et al., 1999)
Cellular Component
CV term Evidence References
integral to membrane inferred from direct assay (Hallem and Carlson, 2006)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
odorant binding inferred from electronic annotation with InterPro:IPR004117 (FlyBase Curators et al., 2004-) olfactory receptor activity inferred by curator from GO:0004888|GO:0007608 (Vosshall et al., 1999) non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1) transmembrane signaling receptor activity inferred from sequence model (Vosshall et al., 1999)
Biological Process
CV term Evidence References
sensory perception of smell non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1)
Cellular Component
CV term Evidence References
integral to membrane inferred from sequence model (Vosshall et al., 1999) non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Or2a allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57744 DroID - A comprehensive database of gene and protein interactions. • FBgn0023523 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31207
Orthologs
OrthoDB Orthologs (28) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6868ZD Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG67H4KJ Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6868ZD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Or2a     Drosophila sechellia   Dsec\GM19218 Y   Drosophila erecta   Dere\GG12926 Y   Drosophila yakuba   Dyak\GE16253 Y   Drosophila ananassae   Dana\GF21970 Y   Drosophila pseudoobscura pseudoobscura   Dpse\Or2a Y   Drosophila persimilis   Dper\GL13334 Y   Drosophila willistoni   Dwil\GK18847 Y   Drosophila virilis   Dvir\GJ16970 Y   Drosophila mojavensis   Dmoj\GI21799 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG67H4KJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB43023 Y Apis mellifera Western honey bee  Amel\GB47987 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037245 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037180 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037200 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016400 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037183 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037143 Y Atta cephalotes Leafcutter ant  Acep\ACEP10733 Y Atta cephalotes Leafcutter ant  Acep\ACEP10722 Y Atta cephalotes Leafcutter ant  Acep\ACEP18667 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO26658 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15955 Y Linepithema humile Argentine ant  Lhum\LH25611 Y Linepithema humile Argentine ant  Lhum\LH25603 Y Solenopsis invicta Red fire ant  Sinv\SINV12181 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI50303 Y Tribolium castaneum Red flour beetle  Tcas\Or147 Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (9) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM19218 Drosophila erecta Dere\GG12926 Drosophila yakuba Dyak\GE16253 Drosophila ananassae Dana\GF21970 Drosophila pseudoobscura pseudoobscura Dpse\Or2a Drosophila persimilis Dper\GL13334 Drosophila willistoni Dwil\GK18847 Drosophila virilis Dvir\GJ16970 Drosophila mojavensis Dmoj\GI21799
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	29302 y1 v1; P{TRiP.JF02442}attP2/TM3, Sb1
VDRC	v101021 P{KK106583}VIE-260B v16233 w1118; P{GD711}v16233 v16234 w1118; P{GD711}v16234/CyO
Genomic Clones ( 2 )
	BACR13K19 BACR48O22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 2 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	RT06583 RT12642
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0023523 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31207
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Or2a Or2F.1 (Warr and Vosshall, 2000.5.19) Source for identity of: Or2F.1 CG3206 (Deng, 1999.11)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080307 RefSeq (Proteins) • NP_525046 DDBJ / EMBL / GenBank • AAD26356 AAF45759 AF127921 AL009171 AL009195 BD268279 CAA15703 Entrez Gene - A searchable database of RefSeq genes. • 31207 UniProtKB/Swiss-Prot • O46077
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Olfactory receptor, Drosophila (IPR004117)
Linkouts
	BioGRID - A database of protein and genetic interactions • 57744 DroID - A comprehensive database of gene and protein interactions. • FBgn0023523 DRSC - Results from RNAi screens. • FBgn0023523 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0023523 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3206-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0023523 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31207 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31207 modMine - Data generated by the modENCODE project. • FBgn0023523
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	2a (Vogt et al., 2002) 2F.1 (Warr and Vosshall, 2000.5.19) AN4 (Warr and Vosshall, 2000.5.19, Gao and Chess, 1999, ) CG3206 (Le Mée et al., 2008, Benos, 2000.12.13, Warr and Vosshall, 2000.5.19, Keleman et al., 2009.8.5, Robertson, 2009, Perkins et al., 2009) DOR2F.1 (Clyne et al., 1999) DOR62 (Warr and Vosshall, 2000.5.19) Dor62 (Vosshall, 1999.2.9) dor62 (Vosshall et al., 1999) EG:30B8.7 (Benos et al., 2001, Benos, 2000.12.13, ) Or2a (Hallem and Carlson, 2006, Kreher et al., 2005, Jafari et al., 2012, Reiter et al., 2007, McBride et al., 2007, van der Goes van Naters and Carlson, 2007, Kreher et al., 2008, Straub et al., 2008, Guo and Kim, 2007, Robertson, 2009, Zhou et al., 2009, Galizia et al., 2010, Guo and Kim, 2010, Montague et al., 2011, Endo et al., 2011) Or2F.1   Or62
Name Synonym	Odorant receptor 2a   Odorant receptor 62   Olfactory receptor 2F.1 (Clyne et al., 1999, )
Secondary FlyBase IDs
References ( 47 )
Generate a list of	All references relating to this gene ( 47 )
List References by type	Research paper  ( 27 ) Supplementary material  ( 3 ) Review  ( 1 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 ) Patent  ( 1 ) Protein sequence record  ( 1 ) Letter  ( 1 )
Recent research papers ( 4 )
	Jafari et al., 2012, PLoS Biol. 10(3): e1001280 Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression. [FBrf0217822] Song et al., 2012, Dev. Cell 22(2): 363--376 Determinants of the Drosophila odorant receptor pattern. [FBrf0217536] Endo et al., 2011, Nat. Neurosci. 15(2): 224--233 Chromatin modification of Notch targets in olfactory receptor neuron diversification. [FBrf0217319] Montague et al., 2011, J. Neurosci. 31(21): 7891--7899 Similar odorants elicit different behavioral and physiological responses, some supersustained. [FBrf0213787] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...