Please see the JBrowse view of Dmel\Ac78C for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
Gene model reviewed during 5.44
Stop-codon suppression (UAG) postulated; FBrf0216884.
gene_with_stop_codon_read_through ; SO:0000697
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
6.5, 4.5 (northern blot)
None of the polypeptides share 100% sequence identity.
1718, 1222 (aa)
The protein contains two modules with six transmembrane helices each; both are required for catalytic activity. Isolated N-terminal or C-terminal guanylate cyclase domains have no catalytic activity, but when they are brought together, enzyme activity is restored. The active site is at the interface of the two domains. Both contribute substrate-binding residues, but the catalytic metal ions are bound exclusively via the N-terminal guanylate cyclase domain.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ac78C using the Feature Mapper tool.
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reference states 2-4 hr AEL
Comment: reference states >=8 hr AEL
GBrowse - Visual display of RNA-Seq signals
View Dmel\Ac78C in GBrowse 23-47
3-47
3-43.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Ac78C CG10554
Release 2 annotation CG10554 corresponds to part of release 3.2 annotation CG10564 (which is Ac78C).
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
May serve to transduce and integrate different developmental signals through the cAMP signalling pathway.