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Gene Dmel\Ac78C

General Information
Symbol	Dmel\Ac78C	Species	D. melanogaster
Name	Adenylyl cyclase 78C	Annotation symbol	CG10564
Feature type	protein_coding_gene	FlyBase ID	FBgn0024150
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	78B3-78C1	Sequence location	3L:21,129,547..21,165,030 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Adenylyl cyclase 78C is referred to in FlyBase by the symbol Dmel\Ac78C (CG10564, FBgn0024150). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: adenylate cyclase activity. There is experimental evidence that it is involved in the biological process: response to sucrose stimulus; response to caffeine; response to trehalose stimulus; detection of chemical stimulus involved in sensory perception of sweet taste. 10 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Adenylate cyclase-like; Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1628412_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Ac78C. Gene sequence location is 3L:21129547..21165030.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 78B3-78C1   Limits computationally determined from genome sequence between P{lacW}l(3)L5541L5541 and P{EP}chbEP3403
Experimentally Determined Cytological Location
Cytogenetic map Notes References 78C-78C   (determined by in situ hybridisation)   (Cann and Levin, 2000) 78C-78C     (Cann, 1999.7.13) 78C-78C     (Cann, 1998.2.9)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ac78C for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.44 Gene model reviewed during 5.46 Stop-codon suppression (UAG) postulated; FBrf0216884. gene_with_stop_codon_read_through ; SO:0000697 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ac78C-RB FBtr0301701  NM_079470   6417   1718 Ac78C-RC FBtr0305501  NM_001259928   4407   1222 Ac78C-RD FBtr0330066  NM_001275208   6206   1694 Ac78C-RE FBtr0330067  NM_001275209   6417   1727 Ac78C-RF FBtr0333358  NM_001275210   6414   1717
Additional Transcript Data & Comments
Reported size (kB)	6.5, 4.5 (northern blot) (Cann and Levin, 2000)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ac78C-PB   FBpp0290915   189.0   1718   6.86     NP_524194   AAF51680 Ac78C-PC   FBpp0293953   135.3   1222   8.04     NP_001246857   AFH04528 Ac78C-PD   FBpp0303099   186.2   1694   7.23     NP_001262137   AGB94830 Ac78C-PE   FBpp0303100   190.0   1727   6.92     NP_001262138   AGB94831 Ac78C-PF   FBpp0305550   188.9   1717   6.86     NP_001262139   AGB94832
Additional Polypeptide Data & Comments
Reported size (kDa)	1718, 1222 (aa) (Cann and Levin, 2000)
Comments	No adenylate cyclase activity was demonstrated in vitro for the shorter Ac78C protein isoform that contains the adenylate cyclase catalytic domains but that lacks the first six of the 12 transmembrane domains present in the longer isoform. (Cann and Levin, 2000) Ac78C protein Catalyzes the synthesis of cAMP in vitro. (Cann and Levin, 2000)
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054) Adenylate cyclase-like (IPR009398) Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site (IPR018297)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF51680   AF047382 AAD44018   AF168678 AAD46380   AE014296 AFH04528   AE014296 AGB94830   AE014296 AGB94831   AE014296 AGB94832   BT100038   CO188101   CO306426   CO316993   CO320805   CO341691   EC059204   EC070683   EC080616   EC254771   GH941807   GH943612   GH969008   GH979042   GH983721
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VP76 Q7KLG6 Q9Y1V0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 4 -- 6   anlage in statu nascendi   (Fisher et al., 2012) organism | gap expression pattern   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   antennal anlage   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage central brain anlage   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage dorsal head epidermis anlage   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage visual anlage   (Fisher et al., 2012) Comment:reported as procephalic ectoderm anlage dorsal ectoderm   (Fisher et al., 2012) organism | gap expression pattern   (Fisher et al., 2012) ventral ectoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic hindgut   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage | late   organism | ubiquitous   (Cann and Levin, 2000) embryonic stage 4 -- 8     (Cann and Levin, 2000) embryonic stage 5 -- 9     (Cann and Levin, 2000) Comment:reference states 2-4 hr AEL embryonic stage 7 -- 8   anterior transverse furrow   (Cann and Levin, 2000) cephalic furrow   (Cann and Levin, 2000) posterior transverse furrow   (Cann and Levin, 2000) embryonic stage 12 -- 17     (Cann and Levin, 2000) Comment:reference states >=8 hr AEL larval stage     (Cann and Levin, 2000) adult stage     (Cann and Levin, 2000)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    197.15 Larval Midgut    25.1 Larval Hindgut    346.9 Larval Malpighian Tubules    170 Larval Fat Body    7.6 Larval Salivary Gland    13.6 Larval Trachea    32.025 Larval Carcass    87.275 Adult Head    51 Adult Eye    20.725 Adult Brain    91.9 Adult Thoracic-Abdominal Ganglion    73.8 Adult Crop    386.5 Adult Midgut    15.3 Adult Hindgut    191.1 Adult Malpighian Tubules    219.8 Adult Fat Body    5 Adult Salivary Gland    6.3 Adult Heart    10.8 Adult VirginFemale Spermatheca    4.5 Adult InseminatedFemale Spermatheca    7.6 Adult Ovary    5.2 Adult Testis    7.8 Adult Male Accessory Gland    41.8 Adult Carcass    23.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    51   NA  Eye    20.725   NA  Brain    91.9   197.15  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    73.8   NA  Crop    386.5   25.1  Midgut    15.3   346.9  Hindgut    191.1   170  Malpighian Tubules    219.8   7.6  Fat Body    5   no informative data  Salivary Gland    6.3   NA  Heart    no informative data   32.025  Trachea    NA   NA  VirginFemale Spermatheca    4.5   NA  InseminatedFemale Spermatheca    7.6   NA  Ovary    5.2   NA  Testis    7.8   NA  Male Accessory Gland    41.8   87.275  Carcass    23.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    4 central nervous system, pupae P8    5 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    2 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    20 embryo 04-06hr    1 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    2 embryo 16-18hr    3 embryo 18-20hr    5 embryo 20-22hr    7 embryo 22-24hr    8 larva L1    5 larva L2    3 larva L3 12hr old    3 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    2 white prepupae new    2 white prepupae 12hr    2 white prepupae 24hr    2 pupae 2d postWPP    1 pupae 3d postWPP    1 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    2 adult male 30day    3 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    11 embryonic GM2    7 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    2 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    7 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    4 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • PC00120 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024150 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10564-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Ac78C Stages(s) 4-6 Stages(s) 7-8
Alleles & Phenotypes
Summary of Allele Phenotypes
Other Phenotypes Allele chemosensitive behavior defective Ac78CΔ32 chemosensitive behavior defective, with Scer\GAL4Gr5a.PU Ac78CdsRNA.Scer\UAS Phenotype manifest in Allele
Classical Alleles ( 7 )
For All Classical Alleles Show
Allele of Ac78C Class Mutagen Stocks Known lesion Ac78CBG01408 1 Yes Ac78CMB00011 1 -- Ac78CMB05598 1 -- Ac78CMI01144 1 -- Ac78CMI04997 1 -- Ac78CMI05462 1 -- Ac78CΔ32 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ac78C Class Mutagen Stocks Known lesion Ac78CGD2764 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Ac78CdsRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes Ac78CScer\UAS.cDa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2764} NA P{UAS-Ac78C.D} NA P{UAS-Ac78C.dsRNA.2914-3376} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}Ac78CMI01144 NA Mi{MIC}Ac78CMI04997 NA Mi{MIC}Ac78CMI05462 NA P{GT1}BG01408 NA insertion of mobile activating element P{EP}chbEP3403 NA P{EP}chbEP3515 NA P{GSV1}C167C167 NA insertion of enhancer trap binary system Mi{ET1}Ac78CMB00011 No Mi{ET1}Ac78CMB05598 No
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
detection of chemical stimulus involved in sensory perception of sweet taste inferred from mutant phenotype (Ueno and Kidokoro, 2008) response to caffeine inferred from direct assay (Ueno and Kidokoro, 2008) response to sucrose stimulus inferred from direct assay (Ueno and Kidokoro, 2008) response to trehalose stimulus inferred from direct assay (Ueno and Kidokoro, 2008)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
adenylate cyclase activity inferred from sequence or structural similarity with UniProtKB:P97490 (FlyBase, 1992-) non-traceable author statement (Cann and Levin, 1997, Morrison et al., 2000)
Biological Process
CV term Evidence References
cyclic nucleotide biosynthetic process inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR009398, InterPro:IPR018297 (FlyBase Curators et al., 2004-) intracellular signal transduction inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR009398 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene_with_stop_codon_read_through (Jungreis et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ac78C allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0024150
Orthologs
OrthoDB Orthologs (71) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6XWGH1 Dipteran inclusive ortholog search EOG65DWXD Insect inclusive ortholog search EOG644JF5 Arthropod inclusive ortholog search EOG6BK3JP Metazoa inclusive ortholog search EOG63NM5J
Orthologs in Drosophila Species (EOG6XWGH1)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Ac78C     Drosophila simulans   Dsim\GD12142 Y   Drosophila sechellia   Dsec\GM22165 Y   Drosophila erecta   Dere\GG13261 Y   Drosophila yakuba   Dyak\GE22359     Drosophila yakuba   Dyak\GE22718     Drosophila yakuba   Dyak\GE22717     Drosophila ananassae   Dana\GF10187 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10398 Y   Drosophila willistoni   Dwil\GK12673 Y   Drosophila virilis   Dvir\GJ11687 Y   Drosophila mojavensis   Dmoj\GI13820 Y   Drosophila grimshawi   Dgri\GH16533 Y
Orthologs in non-Drosophila Dipterans (EOG65DWXD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000062   Anopheles gambiae Malaria mosquito  Agam\AGAP002262   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015189
Orthologs in non-Dipteran Insects (EOG644JF5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB54593   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005856   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005846   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22073   Atta cephalotes Leafcutter ant  Acep\ACEP15162   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17030   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16590   Linepithema humile Argentine ant  Lhum\LH17999   Pogonomyrmex barbatus Red harvester ant  Pbar\PB10775   Solenopsis invicta Red fire ant  Sinv\SINV24699   Acyrthosiphon pisum Pea aphid  Apim\ACYPI002900   Bombyx mori Silkmoth  Bmor\BGIBMGA003315   Pediculus humanus Human body louse  Phum\PHUM176700   Tribolium castaneum Red flour beetle  Tcas\TC013721
Orthologs in non-Insect Arthropods (EOG6BK3JP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_318338   Daphnia pulex Water flea  Dpux\Adcy6   Ixodes scapularis Deer tick  Isca\ISCW002706
Orthologs in non-Arthropod Metazoa (EOG63NM5J)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\acy-4 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007235gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023604gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_017988gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007236gn Y Danio rerio Zebrafish  Drer\ENSDARG00000043141 Y Danio rerio Zebrafish  Drer\ENSDARG00000017437 Y Danio rerio Zebrafish  Drer\adcy6b Y Danio rerio Zebrafish  Drer\adcy1b Y Danio rerio Zebrafish  Drer\ENSDARG00000077145 Y Danio rerio Zebrafish  Drer\adcy8 Y Danio rerio Zebrafish  Drer\ENSDARG00000091342 Y Danio rerio Zebrafish  Drer\si:dkey-206f10.1 Y Danio rerio Zebrafish  Drer\adcy6a Y Danio rerio Zebrafish  Drer\adcy1a Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000024163 Y Xenopus tropicalis Western clawed frog  Xtro\adcy3 Y Xenopus tropicalis Western clawed frog  Xtro\adcy6 Y Xenopus tropicalis Western clawed frog  Xtro\adcy1 Y Gallus gallus Domestic chicken  Ggal\ADCY8 Y Gallus gallus Domestic chicken  Ggal\ADCY5 Y Gallus gallus Domestic chicken  Ggal\ADCY1 Y Gallus gallus Domestic chicken  Ggal\ADCY3 Y Mus musculus House mouse  Mmus\Adcy6 Y Mus musculus House mouse  Mmus\ENSMUSG00000022840 Y Mus musculus House mouse  Mmus\Adcy1 Y Mus musculus House mouse  Mmus\Adcy8 Y Mus musculus House mouse  Mmus\Adcy3 Y Rattus norvegicus Norway rat  Rnor\Adcy8 Y Rattus norvegicus Norway rat  Rnor\Adcy1 Y Rattus norvegicus Norway rat  Rnor\Adcy3 Y Rattus norvegicus Norway rat  Rnor\Adcy5 Y Rattus norvegicus Norway rat  Rnor\Adcy6 Y Homo sapiens Human  Hsap\ENSG00000174233 Y Homo sapiens Human  Hsap\ADCY5 Y Homo sapiens Human  Hsap\ADCY1 Y Homo sapiens Human  Hsap\ADCY8 Y Homo sapiens Human  Hsap\ADCY3 Y
Human Orthologs (5)
Gene OMIM HGNC Hsap\ENSG00000174233     Hsap\ADCY5     Hsap\ADCY1     Hsap\ADCY8     Hsap\ADCY3
AAA Orthologs (9) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12142 Drosophila sechellia Dsec\GM22165 Drosophila erecta Dere\GG13261 Drosophila ananassae Dana\GF10187 Drosophila pseudoobscura pseudoobscura Dpse\GA10398 Drosophila willistoni Dwil\GK12673 Drosophila virilis Dvir\GJ11687 Drosophila mojavensis Dmoj\GI13820 Drosophila grimshawi Dgri\GH16533
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	14392 w1118; P{GT1}BG01408 25224 w1118; Mi{ET1}Ac78CMB05598 34156 y1 w*; Mi{MIC}Ac78CMI01144 42990 y1 w*; Mi{MIC}Ac78CMI04997 43003 y1 w*; Mi{MIC}Ac78CMI05462 22667 y1 w67c23; Mi{ET1}Ac78CMB00011
VDRC	v51978 w1118; P{GD2764}v51978/CyO v51979 w1118; P{GD2764}v51979/CyO
Genomic Clones ( 2 )
	BACR02C22 BACR24H03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 14 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP13601
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	214247.60 CK01.44A.E11 CK01.103C.H3 EK037315 EK251021 EK266538 EK288306 EP12956 RP004206767 RP004248678 RP004254492 RP004262151 RP004446860
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0024150 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40333
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Ac78C CG10554 (FlyBase, 1996-)
Additional comments	Release 2 annotation CG10554 corresponds to part of release 3.2 annotation CG10564 (which is Ac78C). (FlyBase, 1996-)
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) May serve to transduce and integrate different developmental signals through the cAMP signalling pathway. (Cann and Levin, 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079470 NM_001259928 NM_001275208 NM_001275209 NM_001275210 RefSeq (Proteins) • NP_524194 NP_001246857 NP_001262137 NP_001262138 NP_001262139 DDBJ / EMBL / GenBank • AAD44018 AAD46380 AAF51680 AF047382 AF168678 AFH04528 AGB94830 AGB94831 AGB94832 Entrez Gene - A searchable database of RefSeq genes. • 40333 UniProtKB/TrEMBL • Q7KLG6 Q9VP76 Q9Y1V0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054) Adenylate cyclase-like (IPR009398) Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site (IPR018297) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • PC00120
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0024150 DRSC - Results from RNAi screens. • FBgn0024150 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024150 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10564-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0024150 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40333 modMine - Data generated by the modENCODE project. • FBgn0024150
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	AC 78C (Morrison et al., 2000) Ac78C (Molnar et al., 2006, Jungreis et al., 2011, Kwon et al., 2008, Wang et al., 2004) AC78C (Ueno and Kidokoro, 2007, Ueno and Kidokoro, 2008, Duvall and Taghert, 2012) CG10554 (Luschnig, 2003.12.17, ) CG10564 (Morrison et al., 2000, Molnar et al., 2006) DAC78C (Cann and Levin, 2000) DAC78C-s (Cann, 1999.7.13) unnamed (Cann and Levin, 1997)
Name Synonym	Adenylyl cyclase (Ueno and Kidokoro, 2008) Adenylyl cyclase 78C
Secondary FlyBase IDs
	FBgn0040639
References ( 27 )
Generate a list of	All references relating to this gene ( 27 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 2 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 2 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Duvall and Taghert, 2012, PLoS Biol. 10(6): e1001337 The Circadian Neuropeptide PDF Signals Preferentially through a Specific Adenylate Cyclase Isoform AC3 in M Pacemakers of Drosophila. [FBrf0218594] Show all research papers ...