ski, sightless, skinny hedgehog, sit, l(3)63Bg
acetyltransferase acting to acylate Hedgehog or to promote other modifications or trafficking events necessary for Hedgehog function - modifies Spitz to increase the local concentration of the ligand by restricting its diffusion
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rasp using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\rasp in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: sightless CG11495
Source for identity of sightless CG11495 was sequence comparison ( date:010728 ).
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Animals lacking both maternal and zygotic rasp show a segment-polarity phenotype.
Isolated in a screen for maternal effect lethal mutations that affect the process of segmentation.