DLC, dynein light chain, l(2)k10408, LC7
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
97 (aa); 12 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\robl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\robl in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: robl l(2)k10408
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identification: 1 allele of robl has been identified in a screen to isolate genes required for normal neuronal morphogenesis in larval mushroom body neurons.
Identification: Screen for new axonal transport mutants to identify components of the axonal transport process.
Mutants display a larval distal sluggish phenotype and accumulations of motors and cargo in the larval segmental nerves. Mutants also show a strong mitotic defect. Strong alleles of robl show a loss of imaginal tissue growth and abnormal anaphase-telophase mitotic structures in larval brain squashes. Weaker alleles of robl show a rough eye phenotype.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.