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General Information
Symbol
Dmel\chico
Species
D. melanogaster
Name
chico
Annotation Symbol
CG5686
Feature Type
FlyBase ID
FBgn0024248
Gene Model Status
Stock Availability
Gene Snapshot
chico (chico) encodes a substrate of the product of InR. As a key component of the Insulin pathway, the chico product plays an essential role in the control of cell size and growth. [Date last reviewed: 2019-06-13]
Also Known As
IRS, dIRS, fs(2)4, flipper
Key Links
Genomic Location
Cytogenetic map
Sequence location
2L:10,242,512..10,247,078 [-]
Recombination map
2-40
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Protein Family (UniProt)
-
Summaries
Pathway (FlyBase)
Insulin-like Receptor Signaling Pathway Core Components -
The Insulin-like Receptor (IR) signaling pathway in Drosophila is initiated by the binding of an insulin-like peptides to the Insulin-like receptor (InR). (Adapted from FBrf0232297, FBrf0230017 and FBrf0229989.)
Protein Function (UniProtKB)
Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). May mediate the control of various cellular processes by insulin-like peptides. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains. Involved in control of cell proliferation, cell size, and body and organ growth throughout development. Also has a role in a signaling pathway controlling the physiological response required to endure periods of low nutrient conditions. Insulin/insulin-like growth factor (IGF) signaling pathway has a role in regulating aging and is necessary in the ovary for vitellogenic maturation.
(UniProt, Q9XTN2)
Summary (Interactive Fly)
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\chico or the JBrowse view of Dmel\chico for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.46
Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0080088
3229
968
FBtr0303904
3104
968
FBtr0333412
3578
968
Additional Transcript Data and Comments
Reported size (kB)
3.197 (longest cDNA)
3.6 (sequence analysis)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0079677
107.8
968
7.71
FBpp0292907
107.8
968
7.71
FBpp0305604
107.8
968
7.71
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

968 aa isoforms: chico-PA, chico-PB, chico-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
968 (aa); 144 (kD observed); 108 (kD predicted)
968 (aa); 97 (kD predicted)
Comments
External Data
Subunit Structure (UniProtKB)
Bindings to phosphatidylinositol 3-kinase and SHP2.
(UniProt, Q9XTN2)
Crossreferences
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\chico using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (39 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
inferred from genetic interaction with FLYBASE:InR; FB:FBgn0283499
inferred from physical interaction with UniProtKB:P09208
(assigned by UniProt )
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN000064809
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:P35568
(assigned by UniProt )
inferred from sequence or structural similarity with UniProtKB:P35568
(assigned by UniProt )
inferred from biological aspect of ancestor with PANTHER:PTN000064809
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:P35570
(assigned by UniProt )
inferred from sequence or structural similarity with UniProtKB:P35570
(assigned by UniProt )
Biological Process (29 terms)
Terms Based on Experimental Evidence (27 terms)
CV Term
Evidence
References
inferred from mutant phenotype
inferred from mutant phenotype
inferred from physical interaction with UniProtKB:P09208
(assigned by UniProt )
inferred from mutant phenotype
inferred from direct assay
inferred from genetic interaction with FLYBASE:Pi3K92E; FB:FBgn0015279
inferred from genetic interaction with FLYBASE:InR; FB:FBgn0283499
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from direct assay
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
Terms Based on Predictions or Assertions (7 terms)
CV Term
Evidence
References
Cellular Component (6 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
inferred from direct assay
inferred from direct assay
inferred from high throughput direct assay
Terms Based on Predictions or Assertions (5 terms)
CV Term
Evidence
References
inferred from sequence or structural similarity with UniProtKB:P35569
(assigned by UniProt )
inferred from biological aspect of ancestor with PANTHER:PTN000064809
(assigned by GO_Central )
inferred from sequence or structural similarity with UniProtKB:P35569
(assigned by UniProt )
inferred from sequence or structural similarity with UniProtKB:P35569
(assigned by UniProt )
inferred from biological aspect of ancestor with PANTHER:PTN000064809
(assigned by GO_Central )
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
inferred from direct assay
inferred from direct assay
inferred from high throughput direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\chico in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 7 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 20 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of chico
Transgenic constructs containing regulatory region of chico
Deletions and Duplications ( 16 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
larval salivary gland & nucleus
Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (3)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
10 of 15
Yes
Yes
9 of 15
No
Yes
6 of 15
No
Yes
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
9 of 15
Yes
Yes
8 of 15
No
Yes
7 of 15
No
Yes
5 of 15
No
Yes
Rattus norvegicus (Norway rat) (3)
8 of 13
Yes
Yes
7 of 13
No
Yes
5 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (4)
5 of 12
Yes
Yes
4 of 12
No
Yes
4 of 12
No
Yes
1 of 12
No
Yes
Danio rerio (Zebrafish) (6)
9 of 15
Yes
Yes
6 of 15
No
Yes
5 of 15
No
Yes
4 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (0)
No records found.
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091905V2 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503BG )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Anopheles darlingi
American malaria mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W01LR )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Danaus plexippus
Monarch butterfly
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X01JU )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02EF )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Potential Models Based on Orthology ( 2 )
Modifiers Based on Experimental Evidence ( 2 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Interactions Browser

Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
Summary of Genetic Interactions
esyN Network Diagram
esyN Network Key:
Suppression
Enhancement

Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
External Data
Subunit Structure (UniProtKB)
Bindings to phosphatidylinositol 3-kinase and SHP2.
(UniProt, Q9XTN2 )
Linkouts
BioGRID - A database of protein and genetic interactions.
DroID - A comprehensive database of gene and protein interactions.
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Genomic Location and Detailed Mapping Data
Chromosome (arm)
2L
Recombination map
2-40
Cytogenetic map
Sequence location
2L:10,242,512..10,247,078 [-]
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
31B1-31B1
Limits computationally determined from genome sequence between P{lacW}me31Bk06607 and P{PZ}nmd08774
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
31B-31B
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (11)
Genomic Clones (17)
 

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (50)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences
BDGP DGC clones
Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of
    Source for identity of: chico fs(2)4
    Source for database merge of
    Source for merge of: chico anon-WO0078940.1
    Source for merge of: chico anon-WO0078940.4
    Source for merge of: chico BcDNA:GH11263
    Additional comments
    Source for merge of chico anon-WO0078940.1 was sequence comparison ( date:030908 ).
    Source for merge of chico anon-WO0078940.4 was sequence comparison ( date:051113 ).
    Source for merge of chico BcDNA:GH11263 was sequence comparison ( date:991108 ).
    Other Comments
    chico plays an important role in spermatogenesis, by stimulating germline stem cell proliferation and spermatocyte growth.
    dsRNA made from templates generated with primers directed against this gene, when combined with Rheb, raptor, S6k, Pk61C, or Pten dsRNA, inhibits the phosphorylation of Akt1 in S2 cells.
    Removal of foxo accelerates the cell cycle at the expense of cell size in a chico background.
    dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
    chico function is needed for vitellogenesis and to accelerate the rate of follicle cell proliferation within the entire lineage, in response to rich food.
    Animals mutant for chico are less than half the size of wild-type flies owing to fewer and smaller cells.
    Plays an essential role in the control of cell size and growth.
    An insulin receptor substrate.
    Heteroallelic InR mutants and chico mutants exhibit impaired imaginal disc growth, resulting in the generation of small flies.
    Null alleles of chico are semi-viable, but the flies develop slower than sibling controls and have a reduced body size. chico mutant cells differentiate normally but are significantly reduced in size.
    chico is required cell-autonomously in wing and eye imaginal discs. chico interacts strongly with mutations in InR and also with lines overexpressing dominant negative Pi3K92E, thus implying that chico functions in the insulin pathway for cell growth.
    Designation as "flipper" was a symbol misassignment.
    Origin and Etymology
    Discoverer
    Etymology
    chico means small boy in Spanish.
    Identification
    External Crossreferences and Linkouts ( 81 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    KEGG Genes - Molecular building blocks of life in the genomic space.
    KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
    modMine - A data warehouse for the modENCODE project
    SignaLink - A signaling pathway resource with multi-layered regulatory networks.
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyMine - An integrated database for Drosophila genomics
    Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Synonyms and Secondary IDs (20)
    Reported As
    Symbol Synonym
    BcDNA.GH11263
    BcDNA:GH11263
    anon-WO0078940.1
    anon-WO0078940.4
    chic
    chico
    (Birnbaum et al., 2019, Bradshaw, 2019, Huang et al., 2019, Mirzoyan et al., 2019, Rosen et al., 2019, Álvarez-Rendón et al., 2018, Chiku et al., 2018, Funakoshi et al., 2018, Ghiglione et al., 2018, Henstridge et al., 2018, Im et al., 2018, Sharma et al., 2018, Banerjee et al., 2017, Bolukbasi et al., 2017, Park et al., 2017, Stefana et al., 2017, Transgenic RNAi Project members, 2017-, Yun et al., 2017, Zhu et al., 2017, Afschar et al., 2016, Breitkopf et al., 2016, Constantinou et al., 2016, Dobson et al., 2016, Kuleesha et al., 2016, Lee et al., 2016, Lu et al., 2016, Mahoney et al., 2016, Maistrenko et al., 2016, Naganos et al., 2016, Ratliff et al., 2016, Sarov et al., 2016, Schiesari et al., 2016, Vinayagam et al., 2016, Woods et al., 2016, Balakrishnan et al., 2015, Briga and Verhulst, 2015, Chambers et al., 2015, Chen et al., 2015, Grotewiel and Bettinger, 2015, Ismail et al., 2015, Kwon et al., 2015, Mensah et al., 2015, Serbus et al., 2015, Slack et al., 2015, Ugrankar et al., 2015, Charroux and Royet, 2014, Chatterjee et al., 2014, Knight et al., 2014, Mulakkal et al., 2014, Radermacher et al., 2014, Schriner et al., 2014, Almudi et al., 2013, Bai et al., 2013, Banerjee et al., 2013, Demontis et al., 2013, Esslinger et al., 2013, Gems and Partridge, 2013, Hirabayashi et al., 2013, Jagut et al., 2013, Na et al., 2013, Rera et al., 2013, Sopko and Perrimon, 2013, Yang et al., 2013, Adamson and Lajeunesse, 2012, Alvarez-Ponce et al., 2012, Chakrabarti et al., 2012, Iliadi et al., 2012, Kapuria et al., 2012, Kuo et al., 2012, Naganos et al., 2012, Pallares-Cartes et al., 2012, Papatheodorou et al., 2012, Pritchett and McCall, 2012, Tokusumi et al., 2012, Wang et al., 2012, Albrecht et al., 2011, Alic et al., 2011, Bartlett et al., 2011, Boyd et al., 2011, Flatt, 2011, Friedman et al., 2011, Glatter et al., 2011, Jones and Grotewiel, 2011, Karpac et al., 2011, Murillo-Maldonado et al., 2011, Murillo-Maldonado et al., 2011, Partridge et al., 2011, Schachter and Boulianne, 2011, Slack et al., 2011, Tang et al., 2011, Tatar, 2011, Wang et al., 2011, Yamamoto and Tatar, 2011, Zheng et al., 2011, Bauer et al., 2010, Becker et al., 2010, Biteau et al., 2010, Bjedov et al., 2010, Imai et al., 2010, Kockel et al., 2010, Kühnlein, 2010, Paaby et al., 2010, Przybylski et al., 2010, Righi et al., 2010, Slack et al., 2010, Tiefenböck et al., 2010, Alvarez-Ponce et al., 2009, Hull-Thompson et al., 2009, Nuzhdin et al., 2009, Parrish et al., 2009, Ueishi et al., 2009, Vigne et al., 2009, Werz et al., 2009, Honegger et al., 2008, Hsu et al., 2008, LaFever et al., 2008, Libert et al., 2008, Paaby et al., 2008, Wang et al., 2008, Zhou et al., 2008, Giannakou et al., 2007, Libert, 2007, Libert et al., 2007, Luo et al., 2007, Parisi et al., 2007, Shcherbata et al., 2007, Wagaman and Rand, 2007, Christensen and Cook, 2006.8.30, Edgar, 2006, Jaklevic et al., 2006, Martin-Pena et al., 2006, Wu and Brown, 2006, Yang et al., 2006, Corl et al., 2005, Flatt et al., 2005, Richard et al., 2005, Shingleton et al., 2005, Wittwer et al., 2005, Tu and Tatar, 2003, Tu et al., 2002)
    fs(2)ry4
    Secondary FlyBase IDs
    • FBgn0013449
    • FBgn0014169
    • FBgn0028483
    • FBgn0043507
    • FBgn0043508
    Datasets (1)
    Study focus (1)
    Experimental Role
    Project
    Project Type
    Title
    • bait_protein
    Interaction map generated by purification of insulin pathway factors, with identification of copurifying proteins by mass spectrometry.
    References (346)