• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Tsp2A

General Information
Symbol	Dmel\Tsp2A	Species	D. melanogaster
Name	Tetraspanin 2A	Annotation symbol	CG11415
Feature type	protein_coding_gene	FlyBase ID	FBgn0024361
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	EG:8D8.7
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	1F4-1F4	Sequence location	X:1,240,586..1,242,176 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Tetraspanin 2A is referred to in FlyBase by the symbol Dmel\Tsp2A (CG11415, FBgn0024361). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1626767_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Tsp2A. Gene sequence location is X:1240586..1242176.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 1F4-1F4   Limits computationally determined from genome sequence between P{EP}EP1542 and P{EP}futschEP1419
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Tsp2A for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43 Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tsp2A-RA FBtr0070211  NM_080298   1002   244 Tsp2A-RB FBtr0303284  NM_001201594   910   244
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Tsp2A-PA   FBpp0070204   26.9   244   4.35     NP_525037   AAF45608 Tsp2A-PB   FBpp0292376   26.9   244   4.35     NP_001188523   ADV37607
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tetraspanin/Peripherin (IPR018499) Tetraspanin (IPR000301) Tetraspanin, EC2 domain (IPR008952)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF45608   AE014298 ADV37607   AI260717   AL022018 CAA17687   BI242834   BI364234   BI365816   BT014915   CO185922   CO265729   CO290697   CO293997   CO297471   CO298648   CO333608   EC058920   EC066796   EC067953   EC194711   EC198953   EC201382   EC201911   EC217661   EC244714   GH740125   GH745063   GH761442   GH761645   GH761717   GH762228   GH762757   GH765735   GH765803   GH768973   GH779195   GH779617
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O46101
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 7 -- 8   head mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   amnioserosa   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) embryonic stage 11 -- 12   head mesoderm   (Fisher et al., 2012) plasmatocyte primordium   (Fisher et al., 2012) Comment:reported as plasmatocytes anlage procrystal cell   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) embryonic stage 13 -- 16   crystal cell   (Fisher et al., 2012) embryonic brain   (Fisher et al., 2012) embryonic/larval fat body   (Fisher et al., 2012) embryonic/larval garland cell   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) midline ventral glial cell   (Fisher et al., 2012) plasmatocyte   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
[an error occurred while processing this directive] FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
[an error occurred while processing this directive]
modENCODE Development RNA-Seq
[an error occurred while processing this directive] modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
[an error occurred while processing this directive]
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    30 Cadmium 50 mM 12 hrs, larvae L3    28 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    37 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3  (30) Cadmium 50 mM 12 hrs, larvae L3  (28) Cadmium 50 mM 48 hrs, 4-day adult  (32) Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3  (37) Ethanol 10% 3 hrs, larvae L3  (39) Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult  26 Rotenone 2 μg 12 hrs, larvae L3  (46) Rotenone 8 μg 12 hrs, larvae L3  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    30 Cadmium 50 mM 12 hrs, larvae L3    28 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    37 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    30 Cadmium 50 mM 12 hrs, larvae L3    28 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    37 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    45 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    30 Cadmium 50 mM 12 hrs, larvae L3    28 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    37 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3  30 Cadmium 50 mM 12 hrs, larvae L3  28 Cadmium 50 mM 48 hrs, 4-day adult  32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3  (37) Ethanol 10% 3 hrs, larvae L3  (39) Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult  26 Rotenone 2 μg 12 hrs, larvae L3  (46) Rotenone 8 μg 12 hrs, larvae L3  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    30 Cadmium 50 mM 12 hrs, larvae L3    28 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    37 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    30 Cadmium 50 mM 12 hrs, larvae L3    28 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    12 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    37 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    25 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    26 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • RE51204 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024361 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11415-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Tsp2A Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Tsp2A Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Tsp2A Class Mutagen Stocks Known lesion Tsp2AHMS02147 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tsp2AKK106844 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tsp2AGD3188 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Tsp2ANIG.11415R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6227 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3188} NA P{KK106844} NA P{NIG.11415R} NA P{TRiP.HMS02147} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a biological process or molecular function term for this gene. (Based on a review of available data on: 2011-06-30)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR000301, InterPro:IPR008952, InterPro:IPR018499 (FlyBase Curators et al., 2004-) inferred from sequence model (Fradkin et al., 2002) inferred from sequence or structural similarity (Todres et al., 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Tsp2A allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0024361
Orthologs
OrthoDB Orthologs (33) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG62BXVW Dipteran inclusive ortholog search EOG6G7C79 Insect inclusive ortholog search EOG6R7T6W Arthropod inclusive ortholog search EOG676HGC Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG62BXVW)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Tsp2A     Drosophila simulans   Dsim\GD24713 Y   Drosophila sechellia   Dsec\GM19127 Y   Drosophila erecta   Dere\GG12844 Y   Drosophila yakuba   Dyak\GE16679 Y   Drosophila ananassae   Dana\GF21009 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10989 Y   Drosophila persimilis   Dper\GL14243 Y   Drosophila willistoni   Dwil\GK16366 Y   Drosophila virilis   Dvir\GJ18939 Y   Drosophila mojavensis   Dmoj\GI14978 Y   Drosophila grimshawi   Dgri\GH12824 Y
Orthologs in non-Drosophila Dipterans (EOG6G7C79)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000948   Anopheles gambiae Malaria mosquito  Agam\AGAP010598   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017253
Orthologs in non-Dipteran Insects (EOG6R7T6W)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47823   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012185   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15377   Atta cephalotes Leafcutter ant  Acep\ACEP16824   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13170   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13903   Linepithema humile Argentine ant  Lhum\LH18861   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11844   Solenopsis invicta Red fire ant  Sinv\SINV25255   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004993   Bombyx mori Silkmoth  Bmor\BGIBMGA001022   Pediculus humanus Human body louse  Phum\PHUM122270   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07430
Orthologs in non-Insect Arthropods (EOG676HGC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\HA1   Daphnia pulex Water flea  Dpux\JGI_V11_325775   Daphnia pulex Water flea  Dpux\GAGE6   Daphnia pulex Water flea  Dpux\JGI_V11_97163   Ixodes scapularis Deer tick  Isca\ISCW010731
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24713 Drosophila sechellia Dsec\GM19127 Drosophila erecta Dere\GG12844 Drosophila yakuba Dyak\GE16679 Drosophila ananassae Dana\GF21009 Drosophila pseudoobscura pseudoobscura Dpse\GA10989 Drosophila persimilis Dper\GL14243 Drosophila willistoni Dwil\GK16366 Drosophila virilis Dvir\GJ18939 Drosophila mojavensis Dmoj\GI14978 Drosophila grimshawi Dgri\GH12824
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	40899 y1 sc* v1; P{TRiP.HMS02147}attP40
VDRC	v101081 P{KK106844}VIE-260B
Genomic Clones ( 2 )
	BACR09H15 BACR30G24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 32 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE51204
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP04678 RE40274 RE49304
Other clones	33190 33895 75259 83398 167108 281901 CK01.13C.H9 CK01.22B.G5 CK01.96B.A2 EK014429 EK074833 EK143464 EK173423 EK205342 EK217040 EK307434 RP01232 RP001003683 RP001006306 RP001007243 RP001008223 RP001010747 RP001011443 RP001022979 RP001030816 RP001037194 RP001046793 RP001055775
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0024361 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31080
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Tsp2A EG:8D8.7 (Todres et al., 2000)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080298 NM_001201594 RefSeq (Proteins) • NP_525037 NP_001188523 DDBJ / EMBL / GenBank • AAF45608 ADV37607 AI260717 AL022018 BI365816 CAA17687 Entrez Gene - A searchable database of RefSeq genes. • 31080 UniProtKB/TrEMBL • O46101
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tetraspanin/Peripherin (IPR018499) Tetraspanin (IPR000301) Tetraspanin, EC2 domain (IPR008952) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE51204
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0024361 DRSC - Results from RNAi screens. • FBgn0024361 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024361 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11415-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0024361 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31080 modMine - Data generated by the modENCODE project. • FBgn0024361
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG11415 (Fradkin et al., 2002, Benos, 2000.12.13, Todres et al., 2000, Keleman et al., 2009.8.5, Tomancak et al., 2007, Ni et al., 2010.12.1) D8.7 (Seigneuret et al., 2001) Dm.Tsp2A (Todres et al., 2000) EG:8D8.7 (Jasper et al., 2001, Benos et al., 2001, ) Tsp2A (Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	Tetraspanin 2A (Todres et al., 2000)
Secondary FlyBase IDs
References ( 22 )
Generate a list of	All references relating to this gene ( 22 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...