Gene model reviewed during 5.46
Gene model reviewed during 5.56
370 (aa); 41.4 (kD predicted)
Forms a heterodimer with Dp. Interacts with Rbf/Rbf1 and Rbf2. Component of the DREAM complex, which is at least composed of Myb, Caf1, mip40, mip120, mip130, E2f2, Dp, Rbf, Rbf2, lin-52, Rpd3 and l(3)mbt.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\E2f2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\E2f2 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: E2f2 CG1071
E2f2 mutants are viable, but females are partially sterile. Mutant follicle cells terminate endocycles normally, but then fail to confine DNA synthesis to sites of gene amplification and inappropriately begin genomic DNA replication (this ectopic DNA synthesis is not a continuation of the endocycle program).