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Gene Dmel\EfTuM

General Information
Symbol	Dmel\EfTuM	Species	D. melanogaster
Name	Elongation factor Tu mitochondrial	Annotation symbol	CG6050
Feature type	protein_coding_gene	FlyBase ID	FBgn0024556
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	50A14-50A14	Sequence location	2R:9,395,063..9,396,837 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Elongation factor Tu mitochondrial is referred to in FlyBase by the symbol Dmel\EfTuM (CG6050, FBgn0024556). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation elongation factor activity. There is experimental evidence that it is involved in the biological process: Golgi organization; mitotic cell cycle; cell proliferation. 8 alleles are reported. The phenotypes of these alleles are annotated with: digestive system; somatic muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein synthesis factor, GTP-binding; Small GTP-binding protein domain; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu/EF1A, bacterial/organelle; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation/initiation factor/Ribosomal, beta-barrel. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval hindgut, adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1623588_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of EfTuM. Gene sequence location is 2R:9395063..9396837.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features HFA06959 BKN27305
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 50A14-50A14   Limits computationally determined from genome sequence between P{lacW}drkk13809&P{EP}mip120EP606 and P{lacW}l(2)03105k16702&P{lacW}fl(2)dk16105
Experimentally Determined Cytological Location
Cytogenetic map Notes References 89E7-89E9   (determined by in situ hybridisation)   (Spradling et al., 1999) 89E7-89E9     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\EfTuM for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone GM14682 appears problematic: not consistent with >45 other ESTs
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) EfTuM-RA FBtr0087670  NM_080013   1719   489 EfTuM-RB FBtr0301389  NM_001169673   1757   489
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein EfTuM-PA   FBpp0086790   54.0   489   8.15     NP_524752   AAF58366 EfTuM-PB   FBpp0290603   54.0   489   8.15     NP_001163144   AAM68586
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein synthesis factor, GTP-binding (IPR000795) Translation elongation factor EFTu/EF1A, C-terminal (IPR004160) Translation elongation factor EFTu/EF1A, domain 2 (IPR004161) Translation elongation factor EFTu/EF1A, bacterial/organelle (IPR004541) Small GTP-binding protein domain (IPR005225) Translation elongation/initiation factor/Ribosomal, beta-barrel (IPR009000) Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (IPR009001) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME06050
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142134   AA694819   AA695059   AA695589   AA696004   AA821142   AE013599 AAF58366   AE013599 AAM68586   AI062273   AI062873   AI107263   AI109791   AI133969   AI237915   AI292450   AI296153   AI387139   AI387825   AI389461   AI403883   AI512811   AI512838   AI518490   AI546361   AQ026265   AW941399   AY058493 AAL13722   AY440881   BF495742   BF496321   BF497355   BF497569   BF499243   BF500908   BF502509   BF503828   BF506484   BG635995   BG636042   BG637534   BI165758   BI168006   BI168624   BI237930   BI355800   BI573008   BI579808   BI584508   BI591037   BI605060   BI612469   BI616181   BI620544   BI621481   BI621684   BI622538   BI627060   BI633191   BI634817   BI635706   BI641287   BI641850   BT003749   BX011312   BX011601   BX028703   BX034936   BX036881   BX040133   BX041548   BX045451   BX047944   BX051774   BX066079   BX069306   CK604411   CK604412   CK605295   CK657275   CK659207   CK661313   CK661769   CK662170   CL632159   CO296219   CO298543   CO322759   EC082153   EC223558   EC224855   EC226110   EL870317   EL876924   EL883577   EL883771   EL883894   EL885342   EV583268   EV590738   GH754184   GH771533   GH772080   GH773142   GH773462   GH776130   GH776169   GH776361   GH776780   GH777440   GH783331   GH783361   GH788231   GH790600   GH791637   GH792032   GH792888   GH798306   GH798561   GH798705   GH801730   GH802331   GH803226   GH803380   GH811907   GH815143   GH819870   GH822124   GH825096   GH826515   GH828010   GH832975   GH833450   GH835189   GH845840   GH847656   GH850869   GH851307   GH853922   GH854158   GH854677   GH858103   GH860126   GH860966   GH862122   GH867429   GH867678   GH873116   GH875298   GH882326   GH884895   GH885755   GH886573   GH888023   GH891568   GH892562   GH893084   GH893533   GH894660   GH901970   GH903341   GH904404   GH905003   GH905542   GH907638   GH911253   GH914589   GH918330   GH919328   GH919907   GH923459   GH926506   GH926788   GH927922   GH933290   GH935857   GH938658
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95TV3 A1Z9E3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0024556    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0024556 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0024556 expression level Developmental Stage   Expression Level embryo 00-02hr    10127 embryo 02-04hr    4447 embryo 04-06hr    3655 embryo 06-08hr    7558 embryo 08-10hr    9405 embryo 10-12hr    18225 embryo 12-14hr    10643 embryo 14-16hr    17052 embryo 16-18hr    12193 embryo 18-20hr    10428 embryo 20-22hr    10992 embryo 22-24hr    8658 larva L1    21897 larva L2    20418 larva L3 12hr old    14826 larva L3 puffstage 1-2    3231 larva L3 puffstage 3-6    3289 larva L3 puffstage 7-9    3023 white prepupae new    2966 white prepupae 12hr    3487 white prepupae 24hr    4670 pupae 2d postWPP    8646 pupae 3d postWPP    13054 pupae 4d postWPP    11454 adult male 01day    7818 adult male 05day    6778 adult male 30day    7425 adult female 01day    14532 adult female 05day    10201 adult female 30day    10661 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (10127) embryo 02-04hr  (4447) embryo 04-06hr  (3655) embryo 06-08hr  (7558) embryo 08-10hr  (9405) embryo 10-12hr  (18225) embryo 12-14hr  (10643) embryo 14-16hr  (17052) embryo 16-18hr  (12193) embryo 18-20hr  (10428) embryo 20-22hr  (10992) embryo 22-24hr  (8658) larva L1  (21897) larva L2  (20418) larva L3 12hr old  (14826) larva L3 puffstage 1-2  (3231) larva L3 puffstage 3-6  (3289) larva L3 puffstage 7-9  (3023) white prepupae new  (2966) white prepupae 12hr  (3487) white prepupae 24hr  (4670) pupae 2d postWPP  (8646) pupae 3d postWPP  (13054) pupae 4d postWPP  (11454) adult male 01day  (7818) adult male 05day  (6778) adult male 30day  (7425) adult female 01day  (14532) adult female 05day  (10201) adult female 30day  (10661) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (10127) embryo 02-04hr  (4447) embryo 04-06hr  (3655) embryo 06-08hr  (7558) embryo 08-10hr  (9405) embryo 10-12hr  (18225) embryo 12-14hr  (10643) embryo 14-16hr  (17052) embryo 16-18hr  (12193) embryo 18-20hr  (10428) embryo 20-22hr  (10992) embryo 22-24hr  (8658) larva L1  (21897) larva L2  (20418) larva L3 12hr old  (14826) larva L3 puffstage 1-2  (3231) larva L3 puffstage 3-6  (3289) larva L3 puffstage 7-9  (3023) white prepupae new  (2966) white prepupae 12hr  (3487) white prepupae 24hr  (4670) pupae 2d postWPP  (8646) pupae 3d postWPP  (13054) pupae 4d postWPP  (11454) adult male 01day  (7818) adult male 05day  (6778) adult male 30day  (7425) adult female 01day  (14532) adult female 05day  (10201) adult female 30day  (10661) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  10127 embryo 02-04hr    4447 embryo 04-06hr    3655 embryo 06-08hr    7558 embryo 08-10hr    9405 embryo 10-12hr  (18225) embryo 12-14hr  10643 embryo 14-16hr  (17052) embryo 16-18hr  (12193) embryo 18-20hr  10428 embryo 20-22hr  (10992) embryo 22-24hr    8658 larva L1  (21897) larva L2  (20418) larva L3 12hr old  (14826) larva L3 puffstage 1-2    3231 larva L3 puffstage 3-6    3289 larva L3 puffstage 7-9    3023 white prepupae new    2966 white prepupae 12hr    3487 white prepupae 24hr    4670 pupae 2d postWPP    8646 pupae 3d postWPP  (13054) pupae 4d postWPP  (11454) adult male 01day    7818 adult male 05day    6778 adult male 30day    7425 adult female 01day  (14532) adult female 05day  10201 adult female 30day  10661 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    10127 embryo 02-04hr    4447 embryo 04-06hr    3655 embryo 06-08hr    7558 embryo 08-10hr    9405 embryo 10-12hr    18225 embryo 12-14hr    10643 embryo 14-16hr    17052 embryo 16-18hr    12193 embryo 18-20hr    10428 embryo 20-22hr    10992 embryo 22-24hr    8658 larva L1    21897 larva L2    20418 larva L3 12hr old    14826 larva L3 puffstage 1-2    3231 larva L3 puffstage 3-6    3289 larva L3 puffstage 7-9    3023 white prepupae new    2966 white prepupae 12hr    3487 white prepupae 24hr    4670 pupae 2d postWPP    8646 pupae 3d postWPP    13054 pupae 4d postWPP    11454 adult male 01day    7818 adult male 05day    6778 adult male 30day    7425 adult female 01day    14532 adult female 05day    10201 adult female 30day    10661 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0024556 expression level Developmental Stage   Expression Level embryo 00-02hr    10127 embryo 02-04hr    4447 embryo 04-06hr    3655 embryo 06-08hr    7558 embryo 08-10hr    9405 embryo 10-12hr    18225 embryo 12-14hr    10643 embryo 14-16hr    17052 embryo 16-18hr    12193 embryo 18-20hr    10428 embryo 20-22hr    10992 embryo 22-24hr    8658 larva L1    21897 larva L2    20418 larva L3 12hr old    14826 larva L3 puffstage 1-2    3231 larva L3 puffstage 3-6    3289 larva L3 puffstage 7-9    3023 white prepupae new    2966 white prepupae 12hr    3487 white prepupae 24hr    4670 pupae 2d postWPP    8646 pupae 3d postWPP    13054 pupae 4d postWPP    11454 adult male 01day    7818 adult male 05day    6778 adult male 30day    7425 adult female 01day    14532 adult female 05day    10201 adult female 30day    10661 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (10127) embryo 02-04hr  (4447) embryo 04-06hr  (3655) embryo 06-08hr  (7558) embryo 08-10hr  (9405) embryo 10-12hr  (18225) embryo 12-14hr  (10643) embryo 14-16hr  (17052) embryo 16-18hr  (12193) embryo 18-20hr  (10428) embryo 20-22hr  (10992) embryo 22-24hr  (8658) larva L1  (21897) larva L2  (20418) larva L3 12hr old  (14826) larva L3 puffstage 1-2  (3231) larva L3 puffstage 3-6  (3289) larva L3 puffstage 7-9  (3023) white prepupae new  (2966) white prepupae 12hr  (3487) white prepupae 24hr  (4670) pupae 2d postWPP  (8646) pupae 3d postWPP  (13054) pupae 4d postWPP  (11454) adult male 01day  (7818) adult male 05day  (6778) adult male 30day  (7425) adult female 01day  (14532) adult female 05day  (10201) adult female 30day  (10661) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (10127) embryo 02-04hr  (4447) embryo 04-06hr  (3655) embryo 06-08hr  (7558) embryo 08-10hr  (9405) embryo 10-12hr  (18225) embryo 12-14hr  (10643) embryo 14-16hr  (17052) embryo 16-18hr  (12193) embryo 18-20hr  (10428) embryo 20-22hr  (10992) embryo 22-24hr  (8658) larva L1  (21897) larva L2  (20418) larva L3 12hr old  (14826) larva L3 puffstage 1-2  (3231) larva L3 puffstage 3-6  (3289) larva L3 puffstage 7-9  (3023) white prepupae new  (2966) white prepupae 12hr  (3487) white prepupae 24hr  (4670) pupae 2d postWPP  (8646) pupae 3d postWPP  (13054) pupae 4d postWPP  (11454) adult male 01day  (7818) adult male 05day  (6778) adult male 30day  (7425) adult female 01day  (14532) adult female 05day  (10201) adult female 30day  (10661) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  10127 embryo 02-04hr    4447 embryo 04-06hr    3655 embryo 06-08hr    7558 embryo 08-10hr    9405 embryo 10-12hr  18225 embryo 12-14hr  10643 embryo 14-16hr  17052 embryo 16-18hr  12193 embryo 18-20hr  10428 embryo 20-22hr  10992 embryo 22-24hr    8658 larva L1  (21897) larva L2  20418 larva L3 12hr old  14826 larva L3 puffstage 1-2    3231 larva L3 puffstage 3-6    3289 larva L3 puffstage 7-9    3023 white prepupae new    2966 white prepupae 12hr    3487 white prepupae 24hr    4670 pupae 2d postWPP    8646 pupae 3d postWPP  13054 pupae 4d postWPP  11454 adult male 01day    7818 adult male 05day    6778 adult male 30day    7425 adult female 01day  14532 adult female 05day  10201 adult female 30day  10661 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    10127 embryo 02-04hr    4447 embryo 04-06hr    3655 embryo 06-08hr    7558 embryo 08-10hr    9405 embryo 10-12hr    18225 embryo 12-14hr    10643 embryo 14-16hr    17052 embryo 16-18hr    12193 embryo 18-20hr    10428 embryo 20-22hr    10992 embryo 22-24hr    8658 larva L1    21897 larva L2    20418 larva L3 12hr old    14826 larva L3 puffstage 1-2    3231 larva L3 puffstage 3-6    3289 larva L3 puffstage 7-9    3023 white prepupae new    2966 white prepupae 12hr    3487 white prepupae 24hr    4670 pupae 2d postWPP    8646 pupae 3d postWPP    13054 pupae 4d postWPP    11454 adult male 01day    7818 adult male 05day    6778 adult male 30day    7425 adult female 01day    14532 adult female 05day    10201 adult female 30day    10661 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0024556    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0024556 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval hindgut, adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0024556 expression level Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut    558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules    816 Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut  (558.4) Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules  (816) Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut    558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules    816 Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut    558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules    816 Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0024556 expression level Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut    558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules    816 Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut  558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules  (816) Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut    558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules    816 Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    236.8 Larval Hindgut    558.4 Larval Malpighian Tubules    146.6 Larval Fat Body    103.5 Larval Salivary Gland    378.2 Larval Trachea    400.125 Larval Carcass    359.1 Adult Head    262.3 Adult Eye    216.65 Adult Brain    337.1 Adult Thoracic-Abdominal Ganglion    385.1 Adult Crop    306.5 Adult Midgut    272.5 Adult Hindgut    475.6 Adult Malpighian Tubules    816 Adult Fat Body    353.3 Adult Salivary Gland    345.9 Adult Heart    414.775 Adult VirginFemale Spermatheca    374.7 Adult InseminatedFemale Spermatheca    407.5 Adult Ovary    411.3 Adult Testis    106.1 Adult Male Accessory Gland    330.9 Adult Carcass    443.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    262.3   NA  Eye    216.65   NA  Brain    337.1   413.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    385.1   NA  Crop    306.5   236.8  Midgut    272.5   558.4  Hindgut    475.6   146.6  Malpighian Tubules    816   103.5  Fat Body    353.3   378.2  Salivary Gland    345.9   NA  Heart    414.775   400.125  Trachea    NA   NA  VirginFemale Spermatheca    374.7   NA  InseminatedFemale Spermatheca    407.5   NA  Ovary    411.3   NA  Testis    106.1   NA  Male Accessory Gland    330.9   359.1  Carcass    443.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024556 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6050-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive EfTuM34 EfTuML4569 Phenotype manifest in Allele digestive system (with Df(2R)CX1) EfTuML4569 somatic muscle (with Df(2R)CX1) EfTuML4569
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of EfTuM Class Mutagen Stocks Known lesion EfTuMEY08308 P-element activity 2 Yes EfTuML4569 P-element activity 2 Yes EfTuM34 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of EfTuM Class Mutagen Stocks Known lesion EfTuMGD16961 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes EfTuMHMS00655 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes EfTuMKK107305 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes EfTuM+tBa in vitro construct - genomic fragment 0 Yes EfTuMGD6581 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(3R)C4 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Partially disrupted in	Df(2R)mars102 (Zhang et al., 2009)
Disrupted in	Df(2R)BSC274 (Christensen and Cook, 2007.3.22) Df(2R)BSC306 (Christensen and Cook, 2007.5.8) Df(2R)mip12067 (Beall et al., 2007)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6581} NA P{GD16961} NA P{KK107305} NA P{TRiP.HMS00655} NA characterization construct P{EfTuM+tBa} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}EfTuML4569 No P{lacW}l(2)SH0449SH0449 No insertion of mobile activating element P{EPgy2}mip120EY08308 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cell proliferation inferred from mutant phenotype (Kondylis et al., 2011) Golgi organization inferred from mutant phenotype (Kondylis et al., 2011) mitotic cell cycle inferred from mutant phenotype (Kondylis et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from electronic annotation with InterPro:IPR000795 (FlyBase Curators et al., 2004-) GTP binding inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004160, InterPro:IPR004161, InterPro:IPR004541, InterPro:IPR005225 (FlyBase Curators et al., 2004-) translation elongation factor activity inferred from sequence or structural similarity (Spradling et al., 1999) inferred from sequence or structural similarity with Saccharomyces TUF1 (FlyBase, 1992-) inferred from sequence or structural similarity with UniProtKB:P49411 (Sardiello et al., 2003.6.11)
Biological Process
CV term Evidence References
translational elongation inferred from sequence or structural similarity with Saccharomyces TUF1 (FlyBase, 1992-) inferred from sequence or structural similarity with UniProtKB:P49411 (Sardiello et al., 2003.6.11)
Cellular Component
CV term Evidence References
mitochondrion inferred from sequence or structural similarity (Spradling et al., 1999) inferred from sequence or structural similarity with Saccharomyces TUF1 (FlyBase, 1992-) inferred from sequence or structural similarity with UniProtKB:P49411 (Sardiello et al., 2003.6.11)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions EfTuM allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 69061 DroID - A comprehensive database of gene and protein interactions. • FBgn0024556 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44438
Orthologs
Genome-wide drosophilid orthologs	Dana\GF13698 Dere\GG20385 Dgri\GH13998 Dmoj\GI21331 Dper\GL17405 Dpse\GA19322 Dsim\GD10969 Dvir\GJ19676 Dwil\GK15961 Dyak\GE12547
Curated drosophilid orthologs	Dpse\GA19322
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008517-PA Aedes aegypti (mosquito) AGAP006996-PA Anopheles gambiae (mosquito) XP_391880.2 Apis mellifera (honey bee) XP_001948492.1 Acyrthosiphon pisum (pea aphid) At4g02930.1 Arabidopsis thaliana (wall cress) 33786 Batrachochytrium dendrobatidis (chytrid fungus) 103036 Branchiostoma floridae (lancelet) XP_001902322.1 Brugia malayi (roundworm nematode) BGIBMGA006749-PA Bombyx mori (silk worm) ENSBTAP00000025586 Bos taurus (bovine) CAL0005131 Candida albicans (a form of yeast) CN17274 Caenorhabditis brenneri (small nematode) CN18048 Caenorhabditis brenneri (small nematode) CBP36419 Caenorhabditis briggsae (nematode) CE27322 Caenorhabditis elegans (worm) ENSCAFP00000025359 Canis familiaris (dog) CAGL0G09581g Candida glabrata (haploid yeast) ENSCINP00000005794 Ciona intestinalis (sea squirt) JA05473 Caenorhabditis japonica (nematode) CMV191C Cyanidioschyzon merolae (red alga) cn07163 Cryptococcus neoformans (yeast-like fungus) CPIJ009962 Culex pipens (mosquito) ENSCPOP00000009458 Cavia porcellus (guinea pig) 98182 Chlamidomonas reinhardtii (green alga) RP15987 Caenorhabditis remanei (nematode) ENSCSAVP00000015937 Ciona savignyi (sedentary tunicate) 150625 Capitella spl (polychaete worm) DDB0235257 Dictyostelium discoideum (amoeba) DEHA2D08954g Debaryomyces Hansenii (yeast) 307019 Daphnia pulex (daphnia) ENSDARP00000060204 Danio rerio (zebra fish) ENSECAP00000017340 Equus caballus (horse) NP_417798.1 Escherichia coli K12 (bacteria) NP_418407.1 Escherichia coli K12 (bacteria) ENSGACP00000017152 Gymnopilus aculeatus (mushroom) 186271 Hypsipyla robusta (cedar shoot borer) ENSP00000322439 Homo sapiens (human) ISCW010766-PA Ixodes scapularis (deer tick) KLLA0A04587g Kluyveromyces lactis (yeast) KLLA0C05214g Kluyveromyces lactis (yeast) 178160 Lottia gigantea (owl limpet) LmjF18.0740 Leishmania major (virus) ENSMODP00000019426 Monodelphis domestica (gray opossum) ENSMMUP00000004400 Macaca mulatta (rhesus monkey) ENSMUSP00000091180 Mus musculus (house mouse) ENSMUSP00000095656 Mus musculus (house mouse) 229673 Nematostella vectensis (starlet anemone) XP_001604878.1 Nasonia vitripennis (wasp) ENSOANP00000020723 Ornithorynchus anatinus (platypus) ENSORLP00000014404 Oryzias latipes (japanese killifish) LOC_Os03g63410.1 Oryza sativa (asian rice) 8471 Ostreococcus tauri (green alga) MAL13P1.164 Plasmodium falciparum (protozoal parasite) PHUM004190-PA Pediculus humanus (human body louse) PP02359 Pristionchus pacificus (nematode) 142425 Physcomitrella patens (moss) ENSPPYP00000008169 Pongo pygmaeus (orangutan) 71305 Phytophthora ramorum (sudden oak death pathogen) 109196 Phytophthora sojae (root rot pathogen) 793806 Populus trichocarpa (black cottonwood) ENSPTRP00000013572 Pan troglodytes (chimpanzee) PVX_082470 Plasmodium vivax (protozoal parasite) ENSRNOP00000025203 Rattus norvegicus (norway rat) 4740345 Sorghum bicolor (sorghum) YOR187W Saccharomyces cerevisiae (budding yeast) Smp_073500.2 Schistosoma mansoni (trematode parasite) SPBC9B6.04c Schizosaccharomyces pombe (fission yeast) XP_001183305.1 Strongylocentrotus purpuratus (purple sea urchin) 59049 Trichoplax adhaerens (metazoa) TA17805 Theileria annulata (apicomplexan parasite) XP_970339.1 Tribolium castaneum (red flour beetle) Tc00.1047053506357.40 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511277.70 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000014576 Tetraodon nigroviridis (green spotted pufferfish) TP03_0698 Theileria parva (parasitic protozoan) 269616 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020761 Takifugu rubripes (pufferfish Takifugu) 3700.m00233 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000058166 Xenopus tropicalis (frog) YALI0F24387g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17961 NV14357 LH10983 ISCW010766 FBgn0230280 FBgn0217963 FBgn0206818 FBgn0182729 JGI_V11_307019 FBgn0079319 FBgn0155008 FBgn0144061 FBgn0121474 FBgn0112575 FBgn0090725 CPIJ009962 BGIBMGA006749 ACYPI006613 GB18497 AGAP006996 AAEL017378 AAEL008517 PHUM175010 GLEAN_11692
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	32868 y1 sc* v1; P{TRiP.HMS00655}attP2 12215 y1 w1118; P{lacW}EfTuML4569 mip120L4569/CyO 19925 y1 w67c23; P{EPgy2}mip120EY08308 EfTuMEY08308/CyO
Kyoto	114366 yd2 w1118 P{ey-FLP.N}2; P{neoFRT}42D P{lacW}EfTuML4569 /CyO y+ 114575 yd2 w1118 P{ey-FLP.N}2; P{neoFRT}42D P{EPgy2}mip120EY08308 EfTuMEY08308 /CyO y+
VDRC	v108065 P{KK107305}VIE-260B v48981 w1118; P{GD16961}v48981 v48982 w1118; P{GD16961}v48982
Genomic Clones ( 1 )
	BACR36J03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 155 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM14682 RH68252
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05040 AT08967 AT09387 AT10087 AT11511 AT11766 AT13763 AT16060 AT18356 GH01422 GH02227 GH06605 GH09142 GH11284 GH15354 GH17582 GH18489 GH20640 GH23424 GM01540 GM01610 GM02044 GM03082 GM04894 GM32388 LD38023 LD44870 LD44907 LD47921 LP09979 LP16811 LP20721 LP21467 LP22182 LP23446 RE05712 RE08536 RE09444 RE34265 RE73890 RH04742 RH08590 RH23734 RH39056 RH41343 RH46063 RH51711 RH52829 RH53071 RH54430 RH70575 SD13549 SD13624 SD15594 SD17135 SD24514 SD25493 SD27206 UT01819
Other clones	63040 82079 122674 CK01.105C.A10 CK00283 Dmel_dig_006700_0710_1664 Dmel_neb_012189_0437_2861 EK173224 EK188824 EK213052 IP02415 IP06842 IP13234 IP13434 IP13534 IP16605 RP003045327 RP003045999 RP003052081 RP003053177 RP003058042 RP003072125 RP003082960 RP003094362 RP003099018 RP003099291 RP003110151 RP003117098 RP003120913 RP003126864 RP003144776 RP003145080 RP003153800 RP003159090 RP003162790 RP003171993 RP003180912 RP003181052 RP003183979 RP003190821 RP003195300 RP003216857 RP003223192 RP003224167 RP003232265 RP003234468 RP003257310 RP003271299 RP003279827 RP003293130 RP003301259 RP003304096 RP003306561 RP003326920 RP003329979 RP003339660 RP003341965 RP003353091 RP003391354 RP003398093 RP003399082 RP003413597 RP003414544 RP003434042 RP003439447 RP003446458 RP003459592 RP003486394 RP003489032 RP003498225 RP003499881 RP003500947 RP003515385 RP003516670 RP003522668 RP003527157 RP003534137 RP003585083 RP003588190 RP003606037 RP003607416 RP003608000 RP003610075 RP003610283 RP003611536 RP003614566 RP003627544 RP003638874 RP003638966 RP003650286 RP003655097 RP003670564 RP003677736 UT01164
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0024556 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44438
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: EfTuM CG6050 (Misra, 2000.8.9)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080013 NM_001169673 RefSeq (Proteins) • NP_524752 NP_001163144 DDBJ / EMBL / GenBank • AA696004 AA821142 AAF58366 AAL13722 AAM68586 AQ026265 AW941399 AY058493 BI627060 CL632159 Entrez Gene - A searchable database of RefSeq genes. • 44438 UniProtKB/TrEMBL • A1Z9E3 Q95TV3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein synthesis factor, GTP-binding (IPR000795) Translation elongation factor EFTu/EF1A, C-terminal (IPR004160) Translation elongation factor EFTu/EF1A, domain 2 (IPR004161) Translation elongation factor EFTu/EF1A, bacterial/organelle (IPR004541) Small GTP-binding protein domain (IPR005225) Translation elongation/initiation factor/Ribosomal, beta-barrel (IPR009000) Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (IPR009001) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME06050
Linkouts
	BioGRID - A database of protein and genetic interactions • 69061 DroID - A comprehensive database of gene and protein interactions. • FBgn0024556 DRSC - Results from RNAi screens. • FBgn0024556 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024556 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6050-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0024556 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44438 InParanoid A subset of ortholog calls from InParanoid. • AAEL008517-PA Aedes aegypti (mosquito) AGAP006996-PA Anopheles gambiae (mosquito) XP_391880.2 Apis mellifera (honey bee) XP_001948492.1 Acyrthosiphon pisum (pea aphid) At4g02930.1 Arabidopsis thaliana (wall cress) 33786 Batrachochytrium dendrobatidis (chytrid fungus) 103036 Branchiostoma floridae (lancelet) XP_001902322.1 Brugia malayi (roundworm nematode) BGIBMGA006749-PA Bombyx mori (silk worm) ENSBTAP00000025586 Bos taurus (bovine) CAL0005131 Candida albicans (a form of yeast) CN17274 Caenorhabditis brenneri (small nematode) CN18048 Caenorhabditis brenneri (small nematode) CBP36419 Caenorhabditis briggsae (nematode) CE27322 Caenorhabditis elegans (worm) ENSCAFP00000025359 Canis familiaris (dog) CAGL0G09581g Candida glabrata (haploid yeast) ENSCINP00000005794 Ciona intestinalis (sea squirt) JA05473 Caenorhabditis japonica (nematode) CMV191C Cyanidioschyzon merolae (red alga) cn07163 Cryptococcus neoformans (yeast-like fungus) CPIJ009962 Culex pipens (mosquito) ENSCPOP00000009458 Cavia porcellus (guinea pig) 98182 Chlamidomonas reinhardtii (green alga) RP15987 Caenorhabditis remanei (nematode) ENSCSAVP00000015937 Ciona savignyi (sedentary tunicate) 150625 Capitella spl (polychaete worm) DDB0235257 Dictyostelium discoideum (amoeba) DEHA2D08954g Debaryomyces Hansenii (yeast) 307019 Daphnia pulex (daphnia) ENSDARP00000060204 Danio rerio (zebra fish) ENSECAP00000017340 Equus caballus (horse) NP_417798.1 Escherichia coli K12 (bacteria) NP_418407.1 Escherichia coli K12 (bacteria) ENSGACP00000017152 Gymnopilus aculeatus (mushroom) 186271 Hypsipyla robusta (cedar shoot borer) ENSP00000322439 Homo sapiens (human) ISCW010766-PA Ixodes scapularis (deer tick) KLLA0A04587g Kluyveromyces lactis (yeast) KLLA0C05214g Kluyveromyces lactis (yeast) 178160 Lottia gigantea (owl limpet) LmjF18.0740 Leishmania major (virus) ENSMODP00000019426 Monodelphis domestica (gray opossum) ENSMMUP00000004400 Macaca mulatta (rhesus monkey) ENSMUSP00000091180 Mus musculus (house mouse) ENSMUSP00000095656 Mus musculus (house mouse) 229673 Nematostella vectensis (starlet anemone) XP_001604878.1 Nasonia vitripennis (wasp) ENSOANP00000020723 Ornithorynchus anatinus (platypus) ENSORLP00000014404 Oryzias latipes (japanese killifish) LOC_Os03g63410.1 Oryza sativa (asian rice) 8471 Ostreococcus tauri (green alga) MAL13P1.164 Plasmodium falciparum (protozoal parasite) PHUM004190-PA Pediculus humanus (human body louse) PP02359 Pristionchus pacificus (nematode) 142425 Physcomitrella patens (moss) ENSPPYP00000008169 Pongo pygmaeus (orangutan) 71305 Phytophthora ramorum (sudden oak death pathogen) 109196 Phytophthora sojae (root rot pathogen) 793806 Populus trichocarpa (black cottonwood) ENSPTRP00000013572 Pan troglodytes (chimpanzee) PVX_082470 Plasmodium vivax (protozoal parasite) ENSRNOP00000025203 Rattus norvegicus (norway rat) 4740345 Sorghum bicolor (sorghum) YOR187W Saccharomyces cerevisiae (budding yeast) Smp_073500.2 Schistosoma mansoni (trematode parasite) SPBC9B6.04c Schizosaccharomyces pombe (fission yeast) XP_001183305.1 Strongylocentrotus purpuratus (purple sea urchin) 59049 Trichoplax adhaerens (metazoa) TA17805 Theileria annulata (apicomplexan parasite) XP_970339.1 Tribolium castaneum (red flour beetle) Tc00.1047053506357.40 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511277.70 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000014576 Tetraodon nigroviridis (green spotted pufferfish) TP03_0698 Theileria parva (parasitic protozoan) 269616 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020761 Takifugu rubripes (pufferfish Takifugu) 3700.m00233 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000058166 Xenopus tropicalis (frog) YALI0F24387g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44438 modMine - Data generated by the modENCODE project. • FBgn0024556 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17961 NV14357 LH10983 ISCW010766 FBgn0230280 FBgn0217963 FBgn0206818 FBgn0182729 JGI_V11_307019 FBgn0079319 FBgn0155008 FBgn0144061 FBgn0121474 FBgn0112575 FBgn0090725 CPIJ009962 BGIBMGA006749 ACYPI006613 GB18497 AGAP006996 AAEL017378 AAEL008517 PHUM175010 GLEAN_11692
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	CG6050 (Pile et al., 2003, Crosby, 2000.11.17, Beall et al., 2007, Keleman et al., 2009.8.5, Ni et al., 2010.12.1, Cammarato et al., 2011) EfTuM (Christensen and Cook, 2007.3.22, Christensen and Cook, 2007.5.8, Bai et al., 2007, Barnes et al., 2010, Kondylis et al., 2011) eftu-M (Beall et al., 2007) efTuM (Kondylis et al., 2011) l(3)L4569 (BDGP Project Members, 1994-1999, ) mtEF-Tu (Sardiello et al., 2005)
Name Synonym	Elongation factor Tu mitochondrial (Spradling et al., 1999, Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0033847
References ( 31 )
Generate a list of	All references relating to this gene ( 31 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 6 ) Review  ( 1 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 2 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 2 )
	Kondylis et al., 2011, PLoS ONE 6(2): e17173 Identification of ER Proteins Involved in the Functional Organisation of the Early Secretory Pathway in Drosophila Cells by a Targeted RNAi Screen. [FBrf0213167] Barnes et al., 2010, BMC Biochem. 11: 26 Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function. [FBrf0211360] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...