A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\fws

General Information
SymbolDmel\fwsSpeciesD. melanogaster
Namefour way stopAnnotation symbolCG6549
Feature typeprotein_coding_geneFlyBase IDFBgn0024689
Gene Model StatusCurrent Stock availability 2 publicly available
Also Known AsdCOG5, COG5
Genomic Location
Chromosome (arm)2LRecombination map
Cytogenetic map36C10-36C10Sequence location2L:17,478,442..17,481,212 [-]

Genomic Maps

GBrowse View Help
modENCODE GBrowse
detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene four way stop is referred to in FlyBase by the symbol Dmel\fws (CG6549, FBgn0024689). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: contractile ring contraction involved in cell cycle cytokinesis; meiotic spindle stabilization; cytokinesis after meiosis II; cytokinesis after meiosis I. 10 alleles are reported. The phenotypes of these alleles are annotated with: acroblast; Nebenkern; Nebenkern derivative; spermatid; spermatid axoneme. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Conserved oligomeric Golgi complex, subunit 5. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval salivary gland, adult female reproductive system, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1626224_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of fws. Gene sequence location is 2L:17478442..17481212.

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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01
Sequence features
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
36C10-36C10  
Limits computationally determined from genome sequence between P{lacW}Aac11k06710 and P{EP}CG10413EP2164  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
36C-36C  
Location based on deficiency mapping.  
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\fws for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0081001 FBtr0081000 FBtr0305687 FBtr0305685 FBtr0080999 FBtr0080983 FBtr0306162 FBtr0305686 FBtr0305684 FBtr0080998 FBpp0080554 FBpp0296967 FBpp0080553 FBpp0296965 FBpp0296966 FBpp0080552 FBpp0080536 FBpp0297292 FBpp0080551 FBpp0296964 FBti0006726 FBti0110194 FBti0050020 FBti0021545 FBti0047501 FBti0050580
Comments on Gene Model
DGC clone LD01558 appears problematic: incomplete CDS
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0081000
  2476
  751
FBtr0080999
  2466
  751
FBtr0305685
 
  2462
  751
FBtr0305686
 
  2498
  751
FBtr0305687
 
  2416
  751
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
fws-PA  
FBpp0080553  
85.0  
751  
6.69  
fws-PC  
FBpp0080552  
85.0  
751  
6.69  
fws-PD  
FBpp0296965  
85.0  
751  
6.69  
 
 
fws-PE  
FBpp0296966  
85.0  
751  
6.69  
 
 
fws-PF  
FBpp0296967  
85.0  
751  
6.69  
 
 
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view Aac11-RA fws-RA fws-RF fws-RD fws-RC CG5110-RA CG5110-RB fws-RE CG6453-RB CG6453-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0024689


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0024689
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0024689 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 3897
embryo 02-04hr
 
 4899
embryo 04-06hr
 
 1987
embryo 06-08hr
 
 1926
embryo 08-10hr
 
 2168
embryo 10-12hr
 
 1910
embryo 12-14hr
 
 1891
embryo 14-16hr
 
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 
 1595
embryo 22-24hr
 
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 
 2172
adult female 30day
 
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3897)
embryo 02-04hr
 (4899)
embryo 04-06hr
 (1987)
embryo 06-08hr
 (1926)
embryo 08-10hr
 (2168)
embryo 10-12hr
 (1910)
embryo 12-14hr
 (1891)
embryo 14-16hr
 (1631)
embryo 16-18hr
 (1396)
embryo 18-20hr
 (782)
embryo 20-22hr
 (1595)
embryo 22-24hr
 (1597)
larva L1
 (741)
larva L2
 (1068)
larva L3 12hr old
 (719)
larva L3 puffstage 1-2
 (907)
larva L3 puffstage 3-6
 (1067)
larva L3 puffstage 7-9
 (1250)
white prepupae new
 (1320)
white prepupae 12hr
 (960)
white prepupae 24hr
 (1328)
pupae 2d postWPP
 (1199)
pupae 3d postWPP
 (687)
pupae 4d postWPP
 (527)
adult male 01day
 (968)
adult male 05day
 (1067)
adult male 30day
 (1076)
adult female 01day
 (1308)
adult female 05day
 (2172)
adult female 30day
 (2310)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3897)
embryo 02-04hr
 (4899)
embryo 04-06hr
 (1987)
embryo 06-08hr
 (1926)
embryo 08-10hr
 (2168)
embryo 10-12hr
 (1910)
embryo 12-14hr
 (1891)
embryo 14-16hr
 (1631)
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 (1595)
embryo 22-24hr
 (1597)
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 (2172)
adult female 30day
 (2310)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3897
embryo 02-04hr
 
 4899
embryo 04-06hr
 
 1987
embryo 06-08hr
 
 1926
embryo 08-10hr
 
 2168
embryo 10-12hr
 
 1910
embryo 12-14hr
 
 1891
embryo 14-16hr
 
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 
 1595
embryo 22-24hr
 
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 
 2172
adult female 30day
 
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3897
embryo 02-04hr
 
 4899
embryo 04-06hr
 
 1987
embryo 06-08hr
 
 1926
embryo 08-10hr
 
 2168
embryo 10-12hr
 
 1910
embryo 12-14hr
 
 1891
embryo 14-16hr
 
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 
 1595
embryo 22-24hr
 
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 
 2172
adult female 30day
 
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0024689 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 3897
embryo 02-04hr
 
 4899
embryo 04-06hr
 
 1987
embryo 06-08hr
 
 1926
embryo 08-10hr
 
 2168
embryo 10-12hr
 
 1910
embryo 12-14hr
 
 1891
embryo 14-16hr
 
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 
 1595
embryo 22-24hr
 
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 
 2172
adult female 30day
 
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3897)
embryo 02-04hr
 (4899)
embryo 04-06hr
 (1987)
embryo 06-08hr
 (1926)
embryo 08-10hr
 (2168)
embryo 10-12hr
 (1910)
embryo 12-14hr
 (1891)
embryo 14-16hr
 (1631)
embryo 16-18hr
 (1396)
embryo 18-20hr
 (782)
embryo 20-22hr
 (1595)
embryo 22-24hr
 (1597)
larva L1
 (741)
larva L2
 (1068)
larva L3 12hr old
 (719)
larva L3 puffstage 1-2
 (907)
larva L3 puffstage 3-6
 (1067)
larva L3 puffstage 7-9
 (1250)
white prepupae new
 (1320)
white prepupae 12hr
 (960)
white prepupae 24hr
 (1328)
pupae 2d postWPP
 (1199)
pupae 3d postWPP
 (687)
pupae 4d postWPP
 (527)
adult male 01day
 (968)
adult male 05day
 (1067)
adult male 30day
 (1076)
adult female 01day
 (1308)
adult female 05day
 (2172)
adult female 30day
 (2310)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3897)
embryo 02-04hr
 (4899)
embryo 04-06hr
 1987
embryo 06-08hr
 1926
embryo 08-10hr
 2168
embryo 10-12hr
 1910
embryo 12-14hr
 1891
embryo 14-16hr
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 1595
embryo 22-24hr
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 2172
adult female 30day
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3897
embryo 02-04hr
 
 4899
embryo 04-06hr
 
 1987
embryo 06-08hr
 
 1926
embryo 08-10hr
 
 2168
embryo 10-12hr
 
 1910
embryo 12-14hr
 
 1891
embryo 14-16hr
 
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 
 1595
embryo 22-24hr
 
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 
 2172
adult female 30day
 
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3897
embryo 02-04hr
 
 4899
embryo 04-06hr
 
 1987
embryo 06-08hr
 
 1926
embryo 08-10hr
 
 2168
embryo 10-12hr
 
 1910
embryo 12-14hr
 
 1891
embryo 14-16hr
 
 1631
embryo 16-18hr
 
 1396
embryo 18-20hr
 
 782
embryo 20-22hr
 
 1595
embryo 22-24hr
 
 1597
larva L1
 
 741
larva L2
 
 1068
larva L3 12hr old
 
 719
larva L3 puffstage 1-2
 
 907
larva L3 puffstage 3-6
 
 1067
larva L3 puffstage 7-9
 
 1250
white prepupae new
 
 1320
white prepupae 12hr
 
 960
white prepupae 24hr
 
 1328
pupae 2d postWPP
 
 1199
pupae 3d postWPP
 
 687
pupae 4d postWPP
 
 527
adult male 01day
 
 968
adult male 05day
 
 1067
adult male 30day
 
 1076
adult female 01day
 
 1308
adult female 05day
 
 2172
adult female 30day
 
 2310
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0024689


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0024689
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval salivary gland, adult female reproductive system, adult male accessory gland.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0024689 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 (546.2)
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0024689 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 111.925
Larval Midgut
 
 92
Larval Hindgut
 
 109.5
Larval Malpighian Tubules
 
 122.7
Larval Fat Body
 
 109.7
Larval Salivary Gland
 
 436.4
Larval Trachea
 
 97.875
Larval Carcass
 
 87.525
Adult Head
 
 90.7
Adult Eye
 
 90.95
Adult Brain
 
 119.8
Adult Thoracic-Abdominal Ganglion
 
 137.1
Adult Crop
 
 134.9
Adult Midgut
 
 103.7
Adult Hindgut
 
 108.6
Adult Malpighian Tubules
 
 102.9
Adult Fat Body
 
 97.1
Adult Salivary Gland
 
 546.2
Adult Heart
 
 67.175
Adult VirginFemale Spermatheca
 
 88.6
Adult InseminatedFemale Spermatheca
 
 104.3
Adult Ovary
 
 198.1
Adult Testis
 
 58.2
Adult Male Accessory Gland
 
 398.9
Adult Carcass no informative data
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass no informative data

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 90.7
 
NA 
Eye
 
 90.95
 
NA 
Brain
 
 119.8
 
111.925 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 137.1
 
NA 
Crop
 
 134.9
 
92 
Midgut
 
 103.7
 
109.5 
Hindgut
 
 108.6
 
122.7 
Malpighian Tubules
 
 102.9
 
109.7 
Fat Body
 
 97.1
 
436.4 
Salivary Gland
 
 546.2
 
NA 
Heart
 
 67.175
 
97.875 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 88.6
 
NA 
InseminatedFemale Spermatheca
 
 104.3
 
NA 
Ovary
 
 198.1
 
NA 
Testis
 
 58.2
 
NA 
Male Accessory Gland
 
 398.9
 
87.525 
Carcass
 
 no informative data

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyExpress - Embryonic expression images (BDGP data)
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
contractile ring & meiotic telophase I | male
contractile ring & meiotic telophase I | male (with Df(2L)qua1374)
contractile ring & meiotic telophase II | male
contractile ring & meiotic telophase II | male (with Df(2L)qua1374)
spermatid & nucleus | supernumerary
spermatid & nucleus | supernumerary (with Df(2L)qua1374)
spermatocyte & contractile ring
spermatocyte & contractile ring (with Df(2L)qua1374)
spermatocyte & spindle
spermatocyte & spindle (with Df(2L)qua1374)
spindle & meiotic telophase I | male
spindle & meiotic telophase I | male (with Df(2L)qua1374)
spindle & meiotic telophase II | male
spindle & meiotic telophase II | male (with Df(2L)qua1374)
hide Classical Alleles ( 6 )
For All Classical Alleles Show

Allele of fwsClassMutagenStocksKnown lesion
fwsKG028531 --
fwsunspecified
0 --
fwsz-01610 Yes
fwsz-12010 Yes
fwsZ01610 --
fwsZ12010 --
hide Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show

Allele of fwsClassMutagenStocksKnown lesion
fwsGD119571 Yes
fws+t70 Yes
fwsKK1010560 Yes
fwsT:Avic\GFP0 Yes
hide Aneuploid Aberrations
Disrupted in
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
UAS construct
characterization construct
Insertions
Type of insertions
Name
Expression data
miscellaneous insertions
hide Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
hide Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
Cellular Component ( 0 terms)
hide Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
Cellular Component
CV term
References
inferred from sequence or structural similarity with EMBL:AF058718
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hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
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Interacts with
Please look at the allele data for full details of the genetic interactions
fws allele
Gene
References
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InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
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hide Stocks Listed in FlyBase ( 2 )
Bloomington
VDRC
hide Genomic Clones ( 1 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 222 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
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Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Source for merge of: CG6549 anon-EST:Posey162
Source for merge of: fws anon-EST:Posey186
Source for merge of: fws CG6549
Additional comments
hide Other Comments
Mutants are viable and male sterile.
The phenotype of mutants is a failure in meiotic cytokinesis ("four wheel drive" phenotype), as well as a failure in proper polarization and bundling of the cysts of elongating spermatids. The end result is an accumulation of ovoid cysts containing multinucleate spermatids. The flies are male sterile.
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym
anon-EST:Posey162
 
anon-EST:Posey186
 
Name Synonym
Drosophila Cog5
Four-way stop
Four Way Stop
Secondary FlyBase IDs
  • FBgn0027736
  • FBgn0027744
  • FBgn0032641
hide References ( 34 )
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hide Recent research papers ( 1 )
Zhou et al., 2011, Development 138(6): 1111--1120
Auxilin is required for formation of Golgi-derived clathrin-coated vesicles during Drosophila spermatogenesis. [FBrf0213068]
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All reviews listed in FlyBase were published before 2010