Qm, DQM, L10
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.46
Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S) (By similarity).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RpL10 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\RpL10 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: RpL10 Qm
FlyBase Curator comment: This gene has been renamed from 'Qm' to 'RpL10' in order to: i) minimize confusion with the 'qm' gene (FBgn0019662); ii) provide consistent nomenclature for the D. melanogaster ribosomal protein genes; iii) better reflect its orthology with mammalian RPL10. (The gene was originally named 'Qm' in FBrf0101969 based on orthology to the human 'QM' gene. This gene is now known as RPL10 at the HGNC.)
"Qm" likely corresponds to "M(3)80".
Source for merge of Qm BcDNA:LD24589 was a shared cDNA ( date:030728 ).
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Likely Minute gene.
Deletions removing Qm but no other cytoplasmic ribosomal protein-encoding genes show Minute phenotypes.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.