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Gene Dmel\RpL10

General Information
Symbol	Dmel\RpL10	Species	D. melanogaster
Name	Ribosomal protein L10	Annotation symbol	CG17521
Feature type	protein_coding_gene	FlyBase ID	FBgn0024733
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	Qm, DQM
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	80D1-80D1	Sequence location	3L:23,086,290..23,088,571 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein L10 is referred to in FlyBase by the symbol Dmel\RpL10 (CG17521, FBgn0024733). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: centrosome organization; mitotic spindle elongation; mitotic spindle organization; centrosome duplication. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Ribosomal protein L10e; Ribosomal protein L10e, conserved site; Ribosomal protein L10e/L16. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1623754_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Qm. Gene sequence location is 3L:23086290..23088571.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 80D1-80D1   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References h47-h47     (Drosophila Heterochromatin Genome Project, 2004) 80-80     (Nguyen, 1996.2.21) 80A3-80A4   (determined by in situ hybridisation)   (Nguyen-Yue et al., 1997)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpL10 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpL10-RC FBtr0299869  NM_143697   778   218 RpL10-RD FBtr0299870  NM_168984   789   218 RpL10-RE FBtr0333910  NM_001275304   1224   218
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpL10-PC   FBpp0289147   25.5   218   10.35     NP_651954   AAF45440 RpL10-PD   FBpp0289148   25.5   218   10.35     NP_730773   AAG22453 RpL10-PE   FBpp0306039   25.5   218   10.35     NP_001262233   AGB94926
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L10e, conserved site (IPR018255) Ribosomal protein L10e (IPR001197) Ribosomal protein L10e/L16 (IPR016180)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201669   AA263396   AA264352   AA264633   AA390770   AA439683   AA440159   AA440628   AA441654   AA538711   AA538832   AA539951   AA540855   AA567107   AA694892   AA695189   AA696541   AA696740   AA697030   AA735334   AA735385   AA735477   AA802386   AA803079   AA820729   AA949523   AA950141   AA951114   AA951614   AA951929   AA952273   AE014296 AAF45440   AE014296 AAG22453   AF083289   AE014296 AGB94926   AI062511   AI063061   AI063136   AI063949   AI064339   AI107006   AI108537   AI108588   AI134349   AI135134   AI135672   AI238947   AI257206   AI257515   AI259005   AI259739   AI259930   AI260322   AI260497   AI261072   AI292675   AI293586   AI293746   AI294243   AI294819   AI294903   AI294905   AI296803   AI296834   AI297593   AI387460   AI387773   AI388467   AI389605   AI389990   AI402696   AI402879   AI402934   AI403066   AI403318   AI403326   AI403338   AI403629   AI404578   AI404893   AI404942   AI405118   AI455991   AI456064   AI456791   AI511749   AI513046   AI513413   AI513420   AI513863   AI514902   AI517403   AI519584   AI520334   AI520485   AI543073   AK282412   AK339790   AY070910 AAL48532   AY231795   AY232077   AY440350   BE975135   BE975223   BF500486   BF501251   BG632577   BG635433   BG635553   BG636628   BG636957   BG639157   BG640211   BG641066   BI141726   BI161697   BI161698   BI161764   BI161765   BI162965   BI163043   BI163369   BI163645   BI164230   BI164843   BI165841   BI166294   BI166448   BI166951   BI167198   BI167249   BI167412   BI168268   BI169265   BI170161   BI170967   BI171618   BI171947   BI172016   BI172524   BI212364   BI213066   BI214712   BI215106   BI215140   BI215341   BI215659   BI216492   BI216516   BI227826   BI229568   BI229929   BI230190   BI231896   BI234297   BI234797   BI235047   BI235314   BI235488   BI236530   BI236625   BI236828   BI237309   BI238465   BI238664   BI238751   BI238825   BI239771   BI240679   BI242082   BI243933   BI352057   BI352098   BI352522   BI352632   BI352740   BI352867   BI352987   BI353573   BI353809   BI353970   BI354529   BI354658   BI354778   BI354860   BI355339   BI355470   BI355526   BI355703   BI355776   BI356787   BI357262   BI357613   BI358311   BI362002   BI362134   BI362783   BI362788   BI362950   BI364103   BI364332   BI364347   BI365027   BI365917   BI365932   BI368841   BI369058   BI369107   BI369580   BI370446   BI371001   BI372668   BI373356   BI373514   BI374092   BI375987   BI482381   BI482839   BI482901   BI483165   BI483222   BI483678   BI484176   BI485052   BI485337   BI487179   BI564098   BI566537   BI566549   BI568440   BI569258   BI569259   BI569793   BI570456   BI577201   BI577664   BI577948   BI578369   BI578558   BI578818   BI579691   BI580698   BI581667   BI583196   BI584277   BI584354   BI584470   BI584725   BI586552   BI587213   BI588993   BI589010   BI589401   BI590832   BI590884   BI591395   BI606210   BI611963   BI612856   BI612933   BI614900   BI617307   BI619694   BI621998   BI623742   BI623996   BI625693   BI625864   BI627842   BI628228   BI631174   BI633187   BI633381   BI633964   BI634595   BI635016   BI635378   BI635990   BI636007   BI636443   BI637618   BI637909   BI638143   BI639766   BI640351   BI640886   BI641186   BI641546   BI641806   BP540682   BP541097   BP541361   BP541811   BP541911   BP541954   BP542535   BP542794   BP542902   BP543018   BP543021   BP543225   BP543278   BP543483   BP543730   BP543884   BP543927   BP544005   BP544245   BP544343   BP544386   BP544435   BP544483   BP544491   BP544613   BP544969   BP545033   BP545333   BP545404   BP545706   BP545851   BP545852   BP545975   BP545993   BP546082   BP546250   BP546525   BP546776   BP546912   BP547189   BP547209   BP547365   BP547485   BP547676   BP547723   BP547824   BP548022   BP548065   BP548070   BP548441   BP548456   BP548746   BP549043   BP549212   BP549467   BP549528   BP549680   BP549720   BP549783   BP550566   BP551127   BP551519   BP551864   BP552038   BP552339   BP552586   BP552587   BP552753   BP552961   BP552962   BP552970   BP553758   BP553759   BP554473   BP554711   BP554765   BP554814   BP554942   BP555021   BP555896   BP556066   BP556134   BP556151   BP556329   BP556458   BP556484   BP556704   BP557290   BP557523   BP557725   BP557905   BP559005   BP559006   BP559308   BP559318   BP559348   BP559445   BP559966   BP560364   BQ102968   BQ103251   BQ103267   BQ103393   BQ103505   BQ103548   BQ103596   BQ103670   BT003580 AAO39584   BX006619   BX008784   BX010320   BX010775   BX011211   BX011290   BX014896   BX016960   BX017777   BX018772   BX019389   BX019914   BX019929   BX024539   BX025005   BX025237   BX027291   BX032532   BX033805   BX035747   BX037544   BX038979   BX039792   BX040103   BX041060   BX042201   BX043066   BX043332   BX043344   BX043398   BX043998   BX044592   BX044599   BX044813   BX045068   BX045167   BX045235   BX045929   BX046497   BX047148   BX047772   BX048191   BX048384   BX049897   BX050767   BX051693   BX051816   BX052529   BX054398   BX056215   BX057441   BX057966   BX058831   BX059258   BX059294   BX061131   BX062454   BX062474   BX062815   BX062882   BX063569   BX064176   BX064956   BX065177   BX065194   BX066200   BX066414   BX069787   BX070038   BX070072   BX070407   BX070583   BX070863   BX071296   BX071439   BX071887   CA803233   CA804931   CA806580   CA806753   CK131721   CK131801   CK605164   CK605165   CK605482   CK605483   CK657359   CK657822   CK658383   CK659225   CK659534   CK660731   CK661880   CO153373   CO153574   CO153848   CO154019   CO154369   CO154476   CO154565   CO154750   CO155103   CO178562   CO180431   CO180505   CO181495   CO182549   CO182736   CO182798   CO183704   CO183777   CO183842   CO184343   CO184409   CO184416   CO184449   CO184722   CO185284   CO191263   CO191370   CO191857   CO192267   CO192271   CO192397   CO192541   CO192765   CO192978   CO193300   CO194044   CO194143   CO194590   CO195070   CO195711   CO196005   CO265195   CO268439   CO276827   CO284077   CO286574   CO293601   CO293822   CO302287   CO304667   CO319450   CO321615   CO323931   CO335351   CO336080   CO336160   CO336271   CO336425   CO336892   CO337681   CO337697   CO337838   CO338265   CO344342   CR937222   CR937970   CR938096   CR938540   CR938584   CR938586   CR938702   DQ440008   EC057599   EC069769   EC080799   EC204363   EC206992   EC211415   EC211817   EC219916   EC220542   EC224306   EC227402   EC228410   EC233340   EC235817   EC244320   EC250231   EC250232   EC261436   EC262375   EC262533   EC262684   EC263408   EC264069   EC264076   EC264647   EC264670   EC264716   EC265483   EC265960   EC266402   EC266419   EC266487   EC266836   EC266926   EC267384   EC267948   EF070470   EL884847   EL884968   ES691709   ES691710   EV574779   EV575081   EV575287   EV575601   EV575907   EV577622   EV577961   EV577974   EV578123   EV578234   EV578407   EV578788   EV578954   EV579022   EV579135   EV579247   EV579940   EV580245   EV580328   EV580426   EV580685   EV581146   EV581258   EV581310   EV581328   EV581403   EV581411   EV581552   EV581591   EV581625   EV581758   EV581892   EV581967   EV582367   EV582482   EV582837   EV582859   EV583224   EV583294   EV583454   EV583863   EV584132   EV584652   EV584949   EV585503   EV586435   EV587291   EV587396   EV587913   EV589960   EV590093   EV590281   EV590962   EV591715   EV592007   EV592087   EV592149   EV592850   EV593089   EV593410   EV593531   EV593767   EV593794   EV593909   EV594063   EV594195   EV594826   EV594981   EV594985   EV595226   EV595383   EV595442   EV595691   EV595919   EV596349   EV596862   EV597179   EV597983   EV598421   EV598422   EV599177   EV599240   EV599242   EV599291   EV599491   EV599522   EV599826   EV599998   EV600016   EV600369   FD585893   FD586026   FD586317   FD586843   FD587097   GH740105   GH740747   GH741137   GH741235   GH741489   GH742707   GH743141   GH743570   GH744679   GH745072   GH745456   GH745722   GH746672   GH746741   GH746867   GH762494   GH762583   GH762930   GH763078   GH766151   GH766721   GH766831   GH767023   GH768138   GH769509   GO254499   U49721 AAC16108
UniProtKB/Swiss-Prot	O61231
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
cytoplasm inferred from direct assay (Rolls et al., 2007) neuronal cell body inferred from direct assay (Rolls et al., 2007) ribosome inferred from direct assay (Alonso and Santaren, 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2687.5 Larval Midgut    5008.4 Larval Hindgut    4514.2 Larval Malpighian Tubules    5269.6 Larval Fat Body    8296.2 Larval Salivary Gland    7918.3 Larval Trachea    6145 Larval Carcass    4821.25 Adult Head    4683.5 Adult Eye    6083.475 Adult Brain    3019.6 Adult Thoracic-Abdominal Ganglion    4195.3 Adult Crop    6206.3 Adult Midgut    5590.9 Adult Hindgut    5092.1 Adult Malpighian Tubules    6106.1 Adult Fat Body    5674.7 Adult Salivary Gland    12066.7 Adult Heart    6498.025 Adult VirginFemale Spermatheca    5620.4 Adult InseminatedFemale Spermatheca    5823 Adult Ovary    3549.5 Adult Testis    1593.4 Adult Male Accessory Gland    9504.1 Adult Carcass    6059.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2687.5) Larval Midgut  (5008.4) Larval Hindgut  (4514.2) Larval Malpighian Tubules  (5269.6) Larval Fat Body  (8296.2) Larval Salivary Gland  (7918.3) Larval Trachea  (6145) Larval Carcass  (4821.25) Adult Head  (4683.5) Adult Eye  (6083.475) Adult Brain  (3019.6) Adult Thoracic-Abdominal Ganglion  (4195.3) Adult Crop  (6206.3) Adult Midgut  (5590.9) Adult Hindgut  (5092.1) Adult Malpighian Tubules  (6106.1) Adult Fat Body  (5674.7) Adult Salivary Gland  (12066.7) Adult Heart  (6498.025) Adult VirginFemale Spermatheca  (5620.4) Adult InseminatedFemale Spermatheca  (5823) Adult Ovary  (3549.5) Adult Testis  (1593.4) Adult Male Accessory Gland  (9504.1) Adult Carcass  (6059.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2687.5) Larval Midgut  (5008.4) Larval Hindgut  (4514.2) Larval Malpighian Tubules  (5269.6) Larval Fat Body  (8296.2) Larval Salivary Gland  (7918.3) Larval Trachea  (6145) Larval Carcass  (4821.25) Adult Head  (4683.5) Adult Eye  (6083.475) Adult Brain  (3019.6) Adult Thoracic-Abdominal Ganglion  (4195.3) Adult Crop  (6206.3) Adult Midgut  (5590.9) Adult Hindgut  (5092.1) Adult Malpighian Tubules  (6106.1) Adult Fat Body  (5674.7) Adult Salivary Gland  (12066.7) Adult Heart  (6498.025) Adult VirginFemale Spermatheca  (5620.4) Adult InseminatedFemale Spermatheca  (5823) Adult Ovary  (3549.5) Adult Testis  (1593.4) Adult Male Accessory Gland  (9504.1) Adult Carcass  (6059.9) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2687.5 Larval Midgut    5008.4 Larval Hindgut    4514.2 Larval Malpighian Tubules    5269.6 Larval Fat Body    8296.2 Larval Salivary Gland    7918.3 Larval Trachea    6145 Larval Carcass    4821.25 Adult Head    4683.5 Adult Eye    6083.475 Adult Brain    3019.6 Adult Thoracic-Abdominal Ganglion    4195.3 Adult Crop    6206.3 Adult Midgut    5590.9 Adult Hindgut    5092.1 Adult Malpighian Tubules    6106.1 Adult Fat Body    5674.7 Adult Salivary Gland    12066.7 Adult Heart    6498.025 Adult VirginFemale Spermatheca    5620.4 Adult InseminatedFemale Spermatheca    5823 Adult Ovary    3549.5 Adult Testis    1593.4 Adult Male Accessory Gland    9504.1 Adult Carcass    6059.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2687.5 Larval Midgut    5008.4 Larval Hindgut    4514.2 Larval Malpighian Tubules    5269.6 Larval Fat Body    8296.2 Larval Salivary Gland    7918.3 Larval Trachea    6145 Larval Carcass    4821.25 Adult Head    4683.5 Adult Eye    6083.475 Adult Brain    3019.6 Adult Thoracic-Abdominal Ganglion    4195.3 Adult Crop    6206.3 Adult Midgut    5590.9 Adult Hindgut    5092.1 Adult Malpighian Tubules    6106.1 Adult Fat Body    5674.7 Adult Salivary Gland    12066.7 Adult Heart    6498.025 Adult VirginFemale Spermatheca    5620.4 Adult InseminatedFemale Spermatheca    5823 Adult Ovary    3549.5 Adult Testis    1593.4 Adult Male Accessory Gland    9504.1 Adult Carcass    6059.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2687.5) Larval Midgut  (5008.4) Larval Hindgut  (4514.2) Larval Malpighian Tubules  (5269.6) Larval Fat Body  (8296.2) Larval Salivary Gland  (7918.3) Larval Trachea  (6145) Larval Carcass  (4821.25) Adult Head  (4683.5) Adult Eye  (6083.475) Adult Brain  (3019.6) Adult Thoracic-Abdominal Ganglion  (4195.3) Adult Crop  (6206.3) Adult Midgut  (5590.9) Adult Hindgut  (5092.1) Adult Malpighian Tubules  (6106.1) Adult Fat Body  (5674.7) Adult Salivary Gland  (12066.7) Adult Heart  (6498.025) Adult VirginFemale Spermatheca  (5620.4) Adult InseminatedFemale Spermatheca  (5823) Adult Ovary  (3549.5) Adult Testis  (1593.4) Adult Male Accessory Gland  (9504.1) Adult Carcass  (6059.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2687.5) Larval Midgut  (5008.4) Larval Hindgut  (4514.2) Larval Malpighian Tubules  (5269.6) Larval Fat Body  (8296.2) Larval Salivary Gland  (7918.3) Larval Trachea  (6145) Larval Carcass  (4821.25) Adult Head  (4683.5) Adult Eye  (6083.475) Adult Brain  (3019.6) Adult Thoracic-Abdominal Ganglion  (4195.3) Adult Crop  (6206.3) Adult Midgut  (5590.9) Adult Hindgut  (5092.1) Adult Malpighian Tubules  (6106.1) Adult Fat Body  (5674.7) Adult Salivary Gland  (12066.7) Adult Heart  (6498.025) Adult VirginFemale Spermatheca  (5620.4) Adult InseminatedFemale Spermatheca  (5823) Adult Ovary  (3549.5) Adult Testis  1593.4 Adult Male Accessory Gland  (9504.1) Adult Carcass  (6059.9) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2687.5 Larval Midgut    5008.4 Larval Hindgut    4514.2 Larval Malpighian Tubules    5269.6 Larval Fat Body    8296.2 Larval Salivary Gland    7918.3 Larval Trachea    6145 Larval Carcass    4821.25 Adult Head    4683.5 Adult Eye    6083.475 Adult Brain    3019.6 Adult Thoracic-Abdominal Ganglion    4195.3 Adult Crop    6206.3 Adult Midgut    5590.9 Adult Hindgut    5092.1 Adult Malpighian Tubules    6106.1 Adult Fat Body    5674.7 Adult Salivary Gland    12066.7 Adult Heart    6498.025 Adult VirginFemale Spermatheca    5620.4 Adult InseminatedFemale Spermatheca    5823 Adult Ovary    3549.5 Adult Testis    1593.4 Adult Male Accessory Gland    9504.1 Adult Carcass    6059.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4683.5   NA  Eye    6083.475   NA  Brain    3019.6   2687.5  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4195.3   NA  Crop    6206.3   5008.4  Midgut    5590.9   4514.2  Hindgut    5092.1   5269.6  Malpighian Tubules    6106.1   8296.2  Fat Body    5674.7   7918.3  Salivary Gland    12066.7   NA  Heart    6498.025   6145  Trachea    NA   NA  VirginFemale Spermatheca    5620.4   NA  InseminatedFemale Spermatheca    5823   NA  Ovary    3549.5   NA  Testis    1593.4   NA  Male Accessory Gland    9504.1   4821.25  Carcass    6059.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    204 central nervous system, larvae L3    163 central nervous system, pupae P8    135 head, virgin 1-day female    148 head, virgin 4-day female    148 head, virgin 20-day female    264 head, mated 1-day female    101 head, mated 4-day female    180 head, mated 20-day female    211 head, mated 1-day male    99 head, mated 4-day male    128 head, mated 20-day male    186 salivary gland, larvae L3 wandering    191 salivary gland, white prepupae    260 digestive system, larvae L3 wandering    195 digestive system, 1-day adult    178 digestive system, 4-day adult    184 digestive system, 20-day adult    129 fat body, larvae L3 wandering    73 fat body, white prepupae    109 fat body, pupae P8    233 carcass, larvae L3 wandering    216 carcass, 1-day adult    103 carcass, 4-day adult    152 carcass, 20-day adult    141 ovary, virgin 4-day female    392 ovary, mated 4-day female    266 testis, mated 4-day male    126 accessory gland, mated 4-day male    267 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (204) central nervous system, larvae L3  (163) central nervous system, pupae P8  (135) head, virgin 1-day female  (148) head, virgin 4-day female  (148) head, virgin 20-day female  (264) head, mated 1-day female  (101) head, mated 4-day female  (180) head, mated 20-day female  (211) head, mated 1-day male  (99) head, mated 4-day male  (128) head, mated 20-day male  (186) salivary gland, larvae L3 wandering  (191) salivary gland, white prepupae  (260) digestive system, larvae L3 wandering  (195) digestive system, 1-day adult  (178) digestive system, 4-day adult  (184) digestive system, 20-day adult  (129) fat body, larvae L3 wandering  (73) fat body, white prepupae  (109) fat body, pupae P8  (233) carcass, larvae L3 wandering  (216) carcass, 1-day adult  (103) carcass, 4-day adult  (152) carcass, 20-day adult  (141) ovary, virgin 4-day female  (392) ovary, mated 4-day female  (266) testis, mated 4-day male  (126) accessory gland, mated 4-day male  (267) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (204) central nervous system, larvae L3  (163) central nervous system, pupae P8  (135) head, virgin 1-day female  (148) head, virgin 4-day female  (148) head, virgin 20-day female  (264) head, mated 1-day female  101 head, mated 4-day female  (180) head, mated 20-day female  (211) head, mated 1-day male    99 head, mated 4-day male  (128) head, mated 20-day male  (186) salivary gland, larvae L3 wandering  (191) salivary gland, white prepupae  (260) digestive system, larvae L3 wandering  (195) digestive system, 1-day adult  (178) digestive system, 4-day adult  (184) digestive system, 20-day adult  (129) fat body, larvae L3 wandering    73 fat body, white prepupae  (109) fat body, pupae P8  (233) carcass, larvae L3 wandering  (216) carcass, 1-day adult  103 carcass, 4-day adult  (152) carcass, 20-day adult  (141) ovary, virgin 4-day female  (392) ovary, mated 4-day female  (266) testis, mated 4-day male  (126) accessory gland, mated 4-day male  (267) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    204 central nervous system, larvae L3    163 central nervous system, pupae P8    135 head, virgin 1-day female    148 head, virgin 4-day female    148 head, virgin 20-day female    264 head, mated 1-day female    101 head, mated 4-day female    180 head, mated 20-day female    211 head, mated 1-day male    99 head, mated 4-day male    128 head, mated 20-day male    186 salivary gland, larvae L3 wandering    191 salivary gland, white prepupae    260 digestive system, larvae L3 wandering    195 digestive system, 1-day adult    178 digestive system, 4-day adult    184 digestive system, 20-day adult    129 fat body, larvae L3 wandering    73 fat body, white prepupae    109 fat body, pupae P8    233 carcass, larvae L3 wandering    216 carcass, 1-day adult    103 carcass, 4-day adult    152 carcass, 20-day adult    141 ovary, virgin 4-day female    392 ovary, mated 4-day female    266 testis, mated 4-day male    126 accessory gland, mated 4-day male    267 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    204 central nervous system, larvae L3    163 central nervous system, pupae P8    135 head, virgin 1-day female    148 head, virgin 4-day female    148 head, virgin 20-day female    264 head, mated 1-day female    101 head, mated 4-day female    180 head, mated 20-day female    211 head, mated 1-day male    99 head, mated 4-day male    128 head, mated 20-day male    186 salivary gland, larvae L3 wandering    191 salivary gland, white prepupae    260 digestive system, larvae L3 wandering    195 digestive system, 1-day adult    178 digestive system, 4-day adult    184 digestive system, 20-day adult    129 fat body, larvae L3 wandering    73 fat body, white prepupae    109 fat body, pupae P8    233 carcass, larvae L3 wandering    216 carcass, 1-day adult    103 carcass, 4-day adult    152 carcass, 20-day adult    141 ovary, virgin 4-day female    392 ovary, mated 4-day female    266 testis, mated 4-day male    126 accessory gland, mated 4-day male    267 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (204) central nervous system, larvae L3  (163) central nervous system, pupae P8  (135) head, virgin 1-day female  (148) head, virgin 4-day female  (148) head, virgin 20-day female  (264) head, mated 1-day female  (101) head, mated 4-day female  (180) head, mated 20-day female  (211) head, mated 1-day male  (99) head, mated 4-day male  (128) head, mated 20-day male  (186) salivary gland, larvae L3 wandering  (191) salivary gland, white prepupae  (260) digestive system, larvae L3 wandering  (195) digestive system, 1-day adult  (178) digestive system, 4-day adult  (184) digestive system, 20-day adult  (129) fat body, larvae L3 wandering  (73) fat body, white prepupae  (109) fat body, pupae P8  (233) carcass, larvae L3 wandering  (216) carcass, 1-day adult  (103) carcass, 4-day adult  (152) carcass, 20-day adult  (141) ovary, virgin 4-day female  (392) ovary, mated 4-day female  (266) testis, mated 4-day male  (126) accessory gland, mated 4-day male  (267) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (204) central nervous system, larvae L3  (163) central nervous system, pupae P8  135 head, virgin 1-day female  (148) head, virgin 4-day female  (148) head, virgin 20-day female  (264) head, mated 1-day female  101 head, mated 4-day female  (180) head, mated 20-day female  (211) head, mated 1-day male    99 head, mated 4-day male  128 head, mated 20-day male  (186) salivary gland, larvae L3 wandering  (191) salivary gland, white prepupae  (260) digestive system, larvae L3 wandering  (195) digestive system, 1-day adult  (178) digestive system, 4-day adult  (184) digestive system, 20-day adult  129 fat body, larvae L3 wandering    73 fat body, white prepupae  109 fat body, pupae P8  (233) carcass, larvae L3 wandering  (216) carcass, 1-day adult  103 carcass, 4-day adult  (152) carcass, 20-day adult  141 ovary, virgin 4-day female  (392) ovary, mated 4-day female  (266) testis, mated 4-day male  126 accessory gland, mated 4-day male  (267) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    204 central nervous system, larvae L3    163 central nervous system, pupae P8    135 head, virgin 1-day female    148 head, virgin 4-day female    148 head, virgin 20-day female    264 head, mated 1-day female    101 head, mated 4-day female    180 head, mated 20-day female    211 head, mated 1-day male    99 head, mated 4-day male    128 head, mated 20-day male    186 salivary gland, larvae L3 wandering    191 salivary gland, white prepupae    260 digestive system, larvae L3 wandering    195 digestive system, 1-day adult    178 digestive system, 4-day adult    184 digestive system, 20-day adult    129 fat body, larvae L3 wandering    73 fat body, white prepupae    109 fat body, pupae P8    233 carcass, larvae L3 wandering    216 carcass, 1-day adult    103 carcass, 4-day adult    152 carcass, 20-day adult    141 ovary, virgin 4-day female    392 ovary, mated 4-day female    266 testis, mated 4-day male    126 accessory gland, mated 4-day male    267 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1041 embryo 02-04hr    1609 embryo 04-06hr    2047 embryo 06-08hr    1710 embryo 08-10hr    2195 embryo 10-12hr    2757 embryo 12-14hr    2107 embryo 14-16hr    1006 embryo 16-18hr    1422 embryo 18-20hr    1180 embryo 20-22hr    1406 embryo 22-24hr    1793 larva L1    1504 larva L2    1692 larva L3 12hr old    1331 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    841 larva L3 puffstage 7-9    1180 white prepupae new    972 white prepupae 12hr    898 white prepupae 24hr    849 pupae 2d postWPP    824 pupae 3d postWPP    672 pupae 4d postWPP    379 adult male 01day    432 adult male 05day    417 adult male 30day    352 adult female 01day    697 adult female 05day    1343 adult female 30day    1285 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1041) embryo 02-04hr  (1609) embryo 04-06hr  (2047) embryo 06-08hr  (1710) embryo 08-10hr  (2195) embryo 10-12hr  (2757) embryo 12-14hr  (2107) embryo 14-16hr  (1006) embryo 16-18hr  (1422) embryo 18-20hr  (1180) embryo 20-22hr  (1406) embryo 22-24hr  (1793) larva L1  (1504) larva L2  (1692) larva L3 12hr old  (1331) larva L3 puffstage 1-2  (1074) larva L3 puffstage 3-6  (841) larva L3 puffstage 7-9  (1180) white prepupae new  (972) white prepupae 12hr  (898) white prepupae 24hr  (849) pupae 2d postWPP  (824) pupae 3d postWPP  (672) pupae 4d postWPP  (379) adult male 01day  (432) adult male 05day  (417) adult male 30day  (352) adult female 01day  (697) adult female 05day  (1343) adult female 30day  (1285) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1041) embryo 02-04hr  (1609) embryo 04-06hr  (2047) embryo 06-08hr  (1710) embryo 08-10hr  (2195) embryo 10-12hr  (2757) embryo 12-14hr  (2107) embryo 14-16hr  (1006) embryo 16-18hr  (1422) embryo 18-20hr  (1180) embryo 20-22hr  (1406) embryo 22-24hr  (1793) larva L1  (1504) larva L2  (1692) larva L3 12hr old  (1331) larva L3 puffstage 1-2  (1074) larva L3 puffstage 3-6  (841) larva L3 puffstage 7-9  (1180) white prepupae new  (972) white prepupae 12hr  (898) white prepupae 24hr  (849) pupae 2d postWPP  (824) pupae 3d postWPP  (672) pupae 4d postWPP  (379) adult male 01day  (432) adult male 05day  (417) adult male 30day  (352) adult female 01day  (697) adult female 05day  (1343) adult female 30day  (1285) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1041 embryo 02-04hr    1609 embryo 04-06hr    2047 embryo 06-08hr    1710 embryo 08-10hr    2195 embryo 10-12hr    2757 embryo 12-14hr    2107 embryo 14-16hr    1006 embryo 16-18hr    1422 embryo 18-20hr    1180 embryo 20-22hr    1406 embryo 22-24hr    1793 larva L1    1504 larva L2    1692 larva L3 12hr old    1331 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    841 larva L3 puffstage 7-9    1180 white prepupae new    972 white prepupae 12hr    898 white prepupae 24hr    849 pupae 2d postWPP    824 pupae 3d postWPP    672 pupae 4d postWPP    379 adult male 01day    432 adult male 05day    417 adult male 30day    352 adult female 01day    697 adult female 05day    1343 adult female 30day    1285 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1041 embryo 02-04hr    1609 embryo 04-06hr    2047 embryo 06-08hr    1710 embryo 08-10hr    2195 embryo 10-12hr    2757 embryo 12-14hr    2107 embryo 14-16hr    1006 embryo 16-18hr    1422 embryo 18-20hr    1180 embryo 20-22hr    1406 embryo 22-24hr    1793 larva L1    1504 larva L2    1692 larva L3 12hr old    1331 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    841 larva L3 puffstage 7-9    1180 white prepupae new    972 white prepupae 12hr    898 white prepupae 24hr    849 pupae 2d postWPP    824 pupae 3d postWPP    672 pupae 4d postWPP    379 adult male 01day    432 adult male 05day    417 adult male 30day    352 adult female 01day    697 adult female 05day    1343 adult female 30day    1285 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1041) embryo 02-04hr  (1609) embryo 04-06hr  (2047) embryo 06-08hr  (1710) embryo 08-10hr  (2195) embryo 10-12hr  (2757) embryo 12-14hr  (2107) embryo 14-16hr  (1006) embryo 16-18hr  (1422) embryo 18-20hr  (1180) embryo 20-22hr  (1406) embryo 22-24hr  (1793) larva L1  (1504) larva L2  (1692) larva L3 12hr old  (1331) larva L3 puffstage 1-2  (1074) larva L3 puffstage 3-6  (841) larva L3 puffstage 7-9  (1180) white prepupae new  (972) white prepupae 12hr  (898) white prepupae 24hr  (849) pupae 2d postWPP  (824) pupae 3d postWPP  (672) pupae 4d postWPP  (379) adult male 01day  (432) adult male 05day  (417) adult male 30day  (352) adult female 01day  (697) adult female 05day  (1343) adult female 30day  (1285) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1041) embryo 02-04hr  (1609) embryo 04-06hr  (2047) embryo 06-08hr  (1710) embryo 08-10hr  (2195) embryo 10-12hr  (2757) embryo 12-14hr  (2107) embryo 14-16hr  (1006) embryo 16-18hr  (1422) embryo 18-20hr  (1180) embryo 20-22hr  (1406) embryo 22-24hr  (1793) larva L1  (1504) larva L2  (1692) larva L3 12hr old  (1331) larva L3 puffstage 1-2  (1074) larva L3 puffstage 3-6  (841) larva L3 puffstage 7-9  (1180) white prepupae new  (972) white prepupae 12hr  (898) white prepupae 24hr  (849) pupae 2d postWPP  (824) pupae 3d postWPP  (672) pupae 4d postWPP  (379) adult male 01day  (432) adult male 05day  (417) adult male 30day  (352) adult female 01day  (697) adult female 05day  (1343) adult female 30day  (1285) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1041 embryo 02-04hr    1609 embryo 04-06hr    2047 embryo 06-08hr    1710 embryo 08-10hr    2195 embryo 10-12hr    2757 embryo 12-14hr    2107 embryo 14-16hr    1006 embryo 16-18hr    1422 embryo 18-20hr    1180 embryo 20-22hr    1406 embryo 22-24hr    1793 larva L1    1504 larva L2    1692 larva L3 12hr old    1331 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    841 larva L3 puffstage 7-9    1180 white prepupae new    972 white prepupae 12hr    898 white prepupae 24hr    849 pupae 2d postWPP    824 pupae 3d postWPP    672 pupae 4d postWPP    379 adult male 01day    432 adult male 05day    417 adult male 30day    352 adult female 01day    697 adult female 05day    1343 adult female 30day    1285 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1900 Schneider line 2 Sg4    881 embryonic 1182-4H    320 embryonic GM2    667 embryonic Kc167    1387 embryonic S1    268 embryonic S3    688 leg disc CME L1    459 wing disc CME-W2    848 wing disc ML-DmD8    1096 wing disc ML-DmD9    320 wing disc ML-DmD16-c3    404 wing disc ML-DmD21    661 wing disc ML-DmD32    411 haltere disc ML-DmD17-c3    527 eye-antennal disc ML-DmD11    435 antennal disc ML-DmD20-c5    915 mixed discs ML-DmD4-c1    814 CNS ML-DmBG1-c1    550 CNS ML-DmBG2-c2    541 tumorous blood cells mbn2    577 ovary fGS/OSS    170 ovary OSC    268 ovary OSS    122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (1900) Schneider line 2 Sg4  (881) embryonic 1182-4H  (320) embryonic GM2  (667) embryonic Kc167  (1387) embryonic S1  (268) embryonic S3  (688) leg disc CME L1  (459) wing disc CME-W2  (848) wing disc ML-DmD8  (1096) wing disc ML-DmD9  (320) wing disc ML-DmD16-c3  (404) wing disc ML-DmD21  (661) wing disc ML-DmD32  (411) haltere disc ML-DmD17-c3  (527) eye-antennal disc ML-DmD11  (435) antennal disc ML-DmD20-c5  (915) mixed discs ML-DmD4-c1  (814) CNS ML-DmBG1-c1  (550) CNS ML-DmBG2-c2  (541) tumorous blood cells mbn2  (577) ovary fGS/OSS  (170) ovary OSC  (268) ovary OSS  (122) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (1900) Schneider line 2 Sg4  (881) embryonic 1182-4H  (320) embryonic GM2  (667) embryonic Kc167  (1387) embryonic S1  (268) embryonic S3  (688) leg disc CME L1  (459) wing disc CME-W2  (848) wing disc ML-DmD8  (1096) wing disc ML-DmD9  (320) wing disc ML-DmD16-c3  (404) wing disc ML-DmD21  (661) wing disc ML-DmD32  (411) haltere disc ML-DmD17-c3  (527) eye-antennal disc ML-DmD11  (435) antennal disc ML-DmD20-c5  (915) mixed discs ML-DmD4-c1  (814) CNS ML-DmBG1-c1  (550) CNS ML-DmBG2-c2  (541) tumorous blood cells mbn2  (577) ovary fGS/OSS  (170) ovary OSC  (268) ovary OSS  (122) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1900 Schneider line 2 Sg4    881 embryonic 1182-4H    320 embryonic GM2    667 embryonic Kc167    1387 embryonic S1    268 embryonic S3    688 leg disc CME L1    459 wing disc CME-W2    848 wing disc ML-DmD8    1096 wing disc ML-DmD9    320 wing disc ML-DmD16-c3    404 wing disc ML-DmD21    661 wing disc ML-DmD32    411 haltere disc ML-DmD17-c3    527 eye-antennal disc ML-DmD11    435 antennal disc ML-DmD20-c5    915 mixed discs ML-DmD4-c1    814 CNS ML-DmBG1-c1    550 CNS ML-DmBG2-c2    541 tumorous blood cells mbn2    577 ovary fGS/OSS    170 ovary OSC    268 ovary OSS    122 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1900 Schneider line 2 Sg4    881 embryonic 1182-4H    320 embryonic GM2    667 embryonic Kc167    1387 embryonic S1    268 embryonic S3    688 leg disc CME L1    459 wing disc CME-W2    848 wing disc ML-DmD8    1096 wing disc ML-DmD9    320 wing disc ML-DmD16-c3    404 wing disc ML-DmD21    661 wing disc ML-DmD32    411 haltere disc ML-DmD17-c3    527 eye-antennal disc ML-DmD11    435 antennal disc ML-DmD20-c5    915 mixed discs ML-DmD4-c1    814 CNS ML-DmBG1-c1    550 CNS ML-DmBG2-c2    541 tumorous blood cells mbn2    577 ovary fGS/OSS    170 ovary OSC    268 ovary OSS    122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (1900) Schneider line 2 Sg4  (881) embryonic 1182-4H  (320) embryonic GM2  (667) embryonic Kc167  (1387) embryonic S1  (268) embryonic S3  (688) leg disc CME L1  (459) wing disc CME-W2  (848) wing disc ML-DmD8  (1096) wing disc ML-DmD9  (320) wing disc ML-DmD16-c3  (404) wing disc ML-DmD21  (661) wing disc ML-DmD32  (411) haltere disc ML-DmD17-c3  (527) eye-antennal disc ML-DmD11  (435) antennal disc ML-DmD20-c5  (915) mixed discs ML-DmD4-c1  (814) CNS ML-DmBG1-c1  (550) CNS ML-DmBG2-c2  (541) tumorous blood cells mbn2  (577) ovary fGS/OSS  (170) ovary OSC  (268) ovary OSS  (122) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (1900) Schneider line 2 Sg4  (881) embryonic 1182-4H  (320) embryonic GM2  (667) embryonic Kc167  (1387) embryonic S1  (268) embryonic S3  (688) leg disc CME L1  (459) wing disc CME-W2  (848) wing disc ML-DmD8  (1096) wing disc ML-DmD9  (320) wing disc ML-DmD16-c3  (404) wing disc ML-DmD21  (661) wing disc ML-DmD32  (411) haltere disc ML-DmD17-c3  (527) eye-antennal disc ML-DmD11  (435) antennal disc ML-DmD20-c5  (915) mixed discs ML-DmD4-c1  (814) CNS ML-DmBG1-c1  (550) CNS ML-DmBG2-c2  (541) tumorous blood cells mbn2  (577) ovary fGS/OSS  (170) ovary OSC  (268) ovary OSS  122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1900 Schneider line 2 Sg4    881 embryonic 1182-4H    320 embryonic GM2    667 embryonic Kc167    1387 embryonic S1    268 embryonic S3    688 leg disc CME L1    459 wing disc CME-W2    848 wing disc ML-DmD8    1096 wing disc ML-DmD9    320 wing disc ML-DmD16-c3    404 wing disc ML-DmD21    661 wing disc ML-DmD32    411 haltere disc ML-DmD17-c3    527 eye-antennal disc ML-DmD11    435 antennal disc ML-DmD20-c5    915 mixed discs ML-DmD4-c1    814 CNS ML-DmBG1-c1    550 CNS ML-DmBG2-c2    541 tumorous blood cells mbn2    577 ovary fGS/OSS    170 ovary OSC    268 ovary OSS    122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    73 cold shock, 4-day adult    58 heat shock, 4-day adult    337 Cadmium 50 mM 6 hrs, larvae L3    376 Cadmium 50 mM 12 hrs, larvae L3    469 Cadmium 50 mM 48 hrs, 4-day adult    329 Cadmium 100 mM 48 hrs, 4-day adult    229 Copper 0.5 mM 12 hrs, larvae L3    80 Copper 15 mM 48 hrs, 4-day adult    184 Zinc 5 mM 12 hrs, larvae L3    103 Zinc 4.5 mM 48 hrs, 4-day adult    148 Ethanol 2.5% 3 hrs, larvae L3    292 Ethanol 5% 3 hrs, larvae L3    591 Ethanol 10% 3 hrs, larvae L3    311 Caffeine 1.5 mg/ml 4 hrs, larvae L3    438 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    252 Caffeine 25 mg/ml 48 hrs, 4-day adult    85 Paraquat 5 mM 48 hrs, 4-day adult    273 Paraquat 10 mM 48 hrs, 4-day adult    287 Rotenone 2 μg 12 hrs, larvae L3    518 Rotenone 8 μg 12 hrs, larvae L3    240 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (73) cold shock, 4-day adult  (58) heat shock, 4-day adult  (337) Cadmium 50 mM 6 hrs, larvae L3  (376) Cadmium 50 mM 12 hrs, larvae L3  (469) Cadmium 50 mM 48 hrs, 4-day adult  (329) Cadmium 100 mM 48 hrs, 4-day adult  (229) Copper 0.5 mM 12 hrs, larvae L3  (80) Copper 15 mM 48 hrs, 4-day adult  (184) Zinc 5 mM 12 hrs, larvae L3  (103) Zinc 4.5 mM 48 hrs, 4-day adult  (148) Ethanol 2.5% 3 hrs, larvae L3  (292) Ethanol 5% 3 hrs, larvae L3  (591) Ethanol 10% 3 hrs, larvae L3  (311) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (438) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (252) Caffeine 25 mg/ml 48 hrs, 4-day adult  (85) Paraquat 5 mM 48 hrs, 4-day adult  (273) Paraquat 10 mM 48 hrs, 4-day adult  (287) Rotenone 2 μg 12 hrs, larvae L3  (518) Rotenone 8 μg 12 hrs, larvae L3  (240) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    73 cold shock, 4-day adult    58 heat shock, 4-day adult  (337) Cadmium 50 mM 6 hrs, larvae L3  (376) Cadmium 50 mM 12 hrs, larvae L3  (469) Cadmium 50 mM 48 hrs, 4-day adult  (329) Cadmium 100 mM 48 hrs, 4-day adult  (229) Copper 0.5 mM 12 hrs, larvae L3    80 Copper 15 mM 48 hrs, 4-day adult  (184) Zinc 5 mM 12 hrs, larvae L3  103 Zinc 4.5 mM 48 hrs, 4-day adult  (148) Ethanol 2.5% 3 hrs, larvae L3  (292) Ethanol 5% 3 hrs, larvae L3  (591) Ethanol 10% 3 hrs, larvae L3  (311) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (438) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (252) Caffeine 25 mg/ml 48 hrs, 4-day adult    85 Paraquat 5 mM 48 hrs, 4-day adult  (273) Paraquat 10 mM 48 hrs, 4-day adult  (287) Rotenone 2 μg 12 hrs, larvae L3  (518) Rotenone 8 μg 12 hrs, larvae L3  (240) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    73 cold shock, 4-day adult    58 heat shock, 4-day adult    337 Cadmium 50 mM 6 hrs, larvae L3    376 Cadmium 50 mM 12 hrs, larvae L3    469 Cadmium 50 mM 48 hrs, 4-day adult    329 Cadmium 100 mM 48 hrs, 4-day adult    229 Copper 0.5 mM 12 hrs, larvae L3    80 Copper 15 mM 48 hrs, 4-day adult    184 Zinc 5 mM 12 hrs, larvae L3    103 Zinc 4.5 mM 48 hrs, 4-day adult    148 Ethanol 2.5% 3 hrs, larvae L3    292 Ethanol 5% 3 hrs, larvae L3    591 Ethanol 10% 3 hrs, larvae L3    311 Caffeine 1.5 mg/ml 4 hrs, larvae L3    438 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    252 Caffeine 25 mg/ml 48 hrs, 4-day adult    85 Paraquat 5 mM 48 hrs, 4-day adult    273 Paraquat 10 mM 48 hrs, 4-day adult    287 Rotenone 2 μg 12 hrs, larvae L3    518 Rotenone 8 μg 12 hrs, larvae L3    240 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    73 cold shock, 4-day adult    58 heat shock, 4-day adult    337 Cadmium 50 mM 6 hrs, larvae L3    376 Cadmium 50 mM 12 hrs, larvae L3    469 Cadmium 50 mM 48 hrs, 4-day adult    329 Cadmium 100 mM 48 hrs, 4-day adult    229 Copper 0.5 mM 12 hrs, larvae L3    80 Copper 15 mM 48 hrs, 4-day adult    184 Zinc 5 mM 12 hrs, larvae L3    103 Zinc 4.5 mM 48 hrs, 4-day adult    148 Ethanol 2.5% 3 hrs, larvae L3    292 Ethanol 5% 3 hrs, larvae L3    591 Ethanol 10% 3 hrs, larvae L3    311 Caffeine 1.5 mg/ml 4 hrs, larvae L3    438 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    252 Caffeine 25 mg/ml 48 hrs, 4-day adult    85 Paraquat 5 mM 48 hrs, 4-day adult    273 Paraquat 10 mM 48 hrs, 4-day adult    287 Rotenone 2 μg 12 hrs, larvae L3    518 Rotenone 8 μg 12 hrs, larvae L3    240 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (73) cold shock, 4-day adult  (58) heat shock, 4-day adult  (337) Cadmium 50 mM 6 hrs, larvae L3  (376) Cadmium 50 mM 12 hrs, larvae L3  (469) Cadmium 50 mM 48 hrs, 4-day adult  (329) Cadmium 100 mM 48 hrs, 4-day adult  (229) Copper 0.5 mM 12 hrs, larvae L3  (80) Copper 15 mM 48 hrs, 4-day adult  (184) Zinc 5 mM 12 hrs, larvae L3  (103) Zinc 4.5 mM 48 hrs, 4-day adult  (148) Ethanol 2.5% 3 hrs, larvae L3  (292) Ethanol 5% 3 hrs, larvae L3  (591) Ethanol 10% 3 hrs, larvae L3  (311) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (438) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (252) Caffeine 25 mg/ml 48 hrs, 4-day adult  (85) Paraquat 5 mM 48 hrs, 4-day adult  (273) Paraquat 10 mM 48 hrs, 4-day adult  (287) Rotenone 2 μg 12 hrs, larvae L3  (518) Rotenone 8 μg 12 hrs, larvae L3  (240) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    73 cold shock, 4-day adult    58 heat shock, 4-day adult  (337) Cadmium 50 mM 6 hrs, larvae L3  (376) Cadmium 50 mM 12 hrs, larvae L3  (469) Cadmium 50 mM 48 hrs, 4-day adult  (329) Cadmium 100 mM 48 hrs, 4-day adult  (229) Copper 0.5 mM 12 hrs, larvae L3    80 Copper 15 mM 48 hrs, 4-day adult  (184) Zinc 5 mM 12 hrs, larvae L3  103 Zinc 4.5 mM 48 hrs, 4-day adult  (148) Ethanol 2.5% 3 hrs, larvae L3  (292) Ethanol 5% 3 hrs, larvae L3  (591) Ethanol 10% 3 hrs, larvae L3  (311) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (438) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (252) Caffeine 25 mg/ml 48 hrs, 4-day adult    85 Paraquat 5 mM 48 hrs, 4-day adult  (273) Paraquat 10 mM 48 hrs, 4-day adult  (287) Rotenone 2 μg 12 hrs, larvae L3  (518) Rotenone 8 μg 12 hrs, larvae L3  (240) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    73 cold shock, 4-day adult    58 heat shock, 4-day adult    337 Cadmium 50 mM 6 hrs, larvae L3    376 Cadmium 50 mM 12 hrs, larvae L3    469 Cadmium 50 mM 48 hrs, 4-day adult    329 Cadmium 100 mM 48 hrs, 4-day adult    229 Copper 0.5 mM 12 hrs, larvae L3    80 Copper 15 mM 48 hrs, 4-day adult    184 Zinc 5 mM 12 hrs, larvae L3    103 Zinc 4.5 mM 48 hrs, 4-day adult    148 Ethanol 2.5% 3 hrs, larvae L3    292 Ethanol 5% 3 hrs, larvae L3    591 Ethanol 10% 3 hrs, larvae L3    311 Caffeine 1.5 mg/ml 4 hrs, larvae L3    438 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    252 Caffeine 25 mg/ml 48 hrs, 4-day adult    85 Paraquat 5 mM 48 hrs, 4-day adult    273 Paraquat 10 mM 48 hrs, 4-day adult    287 Rotenone 2 μg 12 hrs, larvae L3    518 Rotenone 8 μg 12 hrs, larvae L3    240 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_22 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	BDGP expression data • RE72235 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024733 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17521-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 RpL10GD8605 lethal | pupal stage, with Scer\GAL4pnr-MD237 RpL10GD8605 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of RpL10 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpL10 Class Mutagen Stocks Known lesion RpL10GD8605 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes RpL10JF02520 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpL10KK109426 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpL10NIG.17521R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes RpL10Scer\UAS.T:Avic\GFP-YFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.17521R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from direct assay (Alonso and Santaren, 2006)
Biological Process
CV term Evidence References
centrosome duplication inferred from mutant phenotype (Müller et al., 2010) centrosome organization inferred from mutant phenotype (Müller et al., 2010) mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component
CV term Evidence References
cytoplasm inferred from direct assay (Rolls et al., 2007) neuronal cell body inferred from direct assay (Rolls et al., 2007) ribosome inferred from direct assay (Alonso and Santaren, 2006)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with NCBI_gi:5174431 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1998.12.15)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with NCBI_gi:5174431 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosolic large ribosomal subunit inferred from sequence or structural similarity with NCBI_gi:5174431 (FlyBase, 1992-) ribosome non-traceable author statement (Swiss-Prot Project Members, 1998.12.15)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
RpL10 - CG8207 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpL10 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68678 DroID - A comprehensive database of gene and protein interactions. • FBgn0024733 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43864
Orthologs
OrthoDB Orthologs (44) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6J6SB4 Dipteran inclusive ortholog search EOG6Z62XK Insect inclusive ortholog search EOG6QRG15 Arthropod inclusive ortholog search EOG6V6WZT Metazoa inclusive ortholog search EOG6P8TCD
Orthologs in Drosophila Species (EOG6J6SB4)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RpL10     Drosophila simulans   Dsim\GD12046 Y   Drosophila sechellia   Dsec\GM22490 Y   Drosophila erecta   Dere\GG16295 Y   Drosophila yakuba   Dyak\GE19480 Y   Drosophila ananassae   Dana\GF20520 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA26129 Y   Drosophila persimilis   Dper\GL21963 Y   Drosophila willistoni   Dwil\GK10847 Y   Drosophila virilis   Dvir\GJ17194     Drosophila virilis   Dvir\GJ11194 Y   Drosophila mojavensis   Dmoj\GI23790 Y   Drosophila grimshawi   Dgri\GH19580 Y
Orthologs in non-Drosophila Dipterans (EOG6Z62XK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002534   Anopheles gambiae Malaria mosquito  Agam\AGAP000953   Anopheles gambiae Malaria mosquito  Agam\AGAP002395   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ018688
Orthologs in non-Dipteran Insects (EOG6QRG15)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\RpL10   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003839   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13935   Atta cephalotes Leafcutter ant  Acep\ACEP16250   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22422   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13606   Linepithema humile Argentine ant  Lhum\LH20708   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14941   Solenopsis invicta Red fire ant  Sinv\SINV19424   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007451   Bombyx mori Silkmoth  Bmor\RpL10   Pediculus humanus Human body louse  Phum\PHUM190090   Tribolium castaneum Red flour beetle  Tcas\TC012375
Orthologs in non-Insect Arthropods (EOG6V6WZT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\rbcL   Ixodes scapularis Deer tick  Isca\ISCW017543
Orthologs in non-Arthropod Metazoa (EOG6P8TCD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rpl-10   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006569gn   Danio rerio Zebrafish  Drer\rpl10   Xenopus tropicalis Western clawed frog  Xtro\rpl10   Mus musculus House mouse  Mmus\Rpl10l   Mus musculus House mouse  Mmus\Rpl10   Mus musculus House mouse  Mmus\Rpl10   Rattus norvegicus Norway rat  Rnor\Rpl10   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000039055   Rattus norvegicus Norway rat  Rnor\Rpl10l   Homo sapiens Human  Hsap\RPL10L   Homo sapiens Human  Hsap\RPL10
Human Orthologs (2)
Gene OMIM HGNC Hsap\RPL10L     Hsap\RPL10
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12046 Drosophila sechellia Dsec\GM22490 Drosophila erecta Dere\GG16295 Drosophila yakuba Dyak\GE19480 Drosophila ananassae Dana\GF20520 Drosophila pseudoobscura pseudoobscura Dpse\GA26129 Drosophila persimilis Dper\GL21963 Drosophila willistoni Dwil\GK10847 Drosophila virilis Dvir\GJ11194 Drosophila mojavensis Dmoj\GI23790 Drosophila grimshawi Dgri\GH19580
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	29356 y1 v1; P{TRiP.JF02520}attP2
VDRC	v104504 P{KK109426}VIE-260B v19083 w1118; P{GD8605}v19083 v19084 w1118; P{GD8605}v19084
Genomic Clones ( 2 )
	BACR17M18 BACR29A07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 614 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24589 RE02339
Other clones	yak-ad_qm yak-em_qm
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT16527 GH02487 GH02638 GH04073 GH04719 GH07778 GH10847 GH11788 GH12775 GH13509 GH15096 GH15628 GH18426 GH21429 GH21967 GH22209 GH22274 GH22431 GH22731 GH22739 GH22756 GH23111 GH24340 GH24748 GM01094 GM01741 GM02378 GM04627 GM07854 GM08960 GM17390 GM17619 GM19648 GM20138 GM21119 GM21651 GM24257 GM25764 GM27196 GM27775 GM28247 GM28635 GM30438 GM30929 GM31237 GM32043 GM32306 LD06530 LD08893 LD14759 LD16656 LD18303 LD28356 LD28684 LD29386 LD31419 LD32238 LD36922 LD40660 LD45265 LD45560 LD46531 LP02325 LP03226 LP04110 LP04384 LP05510 LP05913 LP06757 LP06950 LP07567 LP08280 LP10885 LP10929 LP11927 LP12714 LP12815 LP15270 LP16843 LP17357 LP19557 LP21658 LP23576 RE02750 RE13849 RE20819 RE29979 RE30554 RE32601 RE32703 RE34942 RE35274 RE41894 RE47446 RE50246 RE51321 RE51336 RE54885 RE55803 RE56966 RE57794 RE60824 RE65710 RE67235 RE68647 RE70694 RE70853 RE72747 RE73760 RH01944 RH02792 RH04512 RH04570 RH05162 RH21733 RH30661 RH36227 RH53802 RH56575 RH66165 RH69305 SD01338 SD09663 SD11179 SD12304 SD12842 SD13002 SD14377 SD14788 SD15631 SD16713 SD17543 SD17564 SD18126 SD19669 SD20057 SD20359 SD22436 SD23180 SD23910 SD24396 SD24921 SD27195 SD27453 SD28185
Other clones	933 30938 32276 55646 61328 74312 74892 172490 173811 174899 283646 522338 522568 522873 523051 523627 523734 523885 524081 524432 533930 534035 556970 557063 557842 561839 561951 569524 569540 571212 AT15451 bs39a03 bs40a10 CK01.34B.C2 CK01.56C.G4 CK01.60A.D12 CK01.71D.E10 CK01.119D.A4 Dmel_dig_000113_0620_3730 Dmel_dig_000615_0673_3721 Dmel_dig_000919_0703_0331 Dmel_dig_001942_0678_3475 Dmel_dig_002244_0668_2703 Dmel_dig_002630_0717_0495 Dmel_dig_003159_0635_0899 Dmel_dig_003833_0584_2559 Dmel_dig_004141_0708_3341 Dmel_dig_005145_0646_3739 Dmel_dig_005902_0668_2201 Dmel_dig_007010_0618_2773 Dmel_dig_007192_0673_2949 Dmel_dig_007332_0591_2683 Dmel_dig_007688_0690_3554 Dmel_dig_008160_0693_0670 Dmel_dig_009815_0595_3227 Dmel_dig_011359_0701_2646 Dmel_dig_011403_0582_2010 Dmel_dig_011469_0643_2236 Dmel_dig_011830_0631_1552 Dmel_dig_012218_0660_3542 Dmel_dig_012229_0658_3482 Dmel_dig_012252_0670_2782 Dmel_dig_012742_0660_1396 Dmel_dig_012778_0641_0463 Dmel_dig_013252_0601_1285 Dmel_dig_013857_0651_0964 Dmel_dig_014323_0661_2681 Dmel_dig_014571_0685_2930 Dmel_dig_014827_0642_3372 Dmel_dig_014951_0665_1225 Dmel_dig_015028_0656_0849 Dmel_dig_016222_0716_0467 Dmel_dig_016739_0622_1030 Dmel_dig_016841_0601_2458 Dmel_dig_017147_0604_0674 Dmel_dig_017167_0627_1019 Dmel_dig_017669_0693_1820 Dmel_dig_017896_0659_1760 Dmel_dig_018173_0588_3337 Dmel_dig_018213_0671_2100 Dmel_dig_019578_0626_3336 Dmel_dig_020497_0678_2420 Dmel_dig_020564_0715_2612 Dmel_neb_001696_0824_2559 Dmel_neb_002604_0654_0282 Dmel_neb_004591_0837_0417 Dmel_neb_004732_0680_3395 Dmel_neb_005273_0695_2299 Dmel_neb_006263_0825_2961 Dmel_neb_007911_0899_3051 Dmel_neb_008620_0644_1676 Dmel_neb_009330_0579_2153 Dmel_neb_009374_0925_1987 Dmel_neb_010148_0919_1282 Dmel_neb_010333_0692_2265 Dmel_neb_010493_0609_3561 Dmel_neb_010628_0632_2807 Dmel_neb_010641_0626_2734 Dmel_neb_010882_0697_1659 Dmel_neb_011321_0900_1540 Dmel_neb_011585_0346_1983 Dmel_neb_011631_0931_1408 Dmel_neb_011817_0613_2845 Dmel_neb_011913_0926_0727 Dmel_neb_012183_0651_0859 Dmel_neb_012238_0642_2308 Dmel_neb_012240_0908_0802 Dmel_neb_012271_0957_0317 Dmel_neb_012382_0584_2911 Dmel_neb_012680_0827_1804 Dmel_neb_012830_0690_0581 Dmel_neb_012838_0407_1180 Dmel_neb_013229_0624_1571 Dmel_neb_013391_0180_2699 Dmel_neb_013398_0952_1405 Dmel_neb_013645_0922_3215 Dmel_neb_013742_0905_2007 Dmel_neb_013976_0336_3267 Dmel_neb_014076_0644_2248 Dmel_neb_014529_0192_2687 Dmel_neb_014607_0193_3261 Dmel_neb_014708_0702_0533 Dmel_neb_014750_0670_2580 Dmel_neb_014765_0696_3252 Dmel_neb_014856_0156_2674 Dmel_neb_015389_0397_1083 Dmel_neb_015466_0854_2016 Dmel_neb_015755_0343_1097 EC01546 EC01931 EC14422 EC22953 EC23841 EC24038 EC26169 EC26319 EC26517 EC27942 EC28053 EC28062 EC28109 EC28471 EC30141 EC30588 EC30766 EC32286 EC33457 EC33461 EC33630 EC34002 EC34441 EC34935 EC35553 EC37319 EC37517 EC38864 EC39663 EC40824 EC43876 EK057038 EK063248 EK091334 EK122146 EK141826 EK165207 EK183827 EK186029 EK192002 EK203818 EK204928 EK245501 EK278150 EN01840 EN02356 EN02937 EN03320 EN04010 EN04214 EN04359 EN04726 EN05362 EN10063 EN11760 EN11951 EN12204 EN12516 EN13435 EN15055 EN15117 EN15405 EN16341 EP19103 ESG011b.E7_A03 ESG014a.E21_C07 ESG014d.E21_F02 ESG0115d.B21_D02 FGA007A07 FGA010E11 FGB002C08 FGC005F07 FGC007A06 FGC007E01 FGC014B10 FGC017A04 FGC017E11 FGC018B11 FGC018C01 FGC019C12 FGC019F03 FGC020G01 FGC022A11 FGC022H08 FGC023B06 FGC023E11 FGC024H01 FGC025D03 FGC025F02 FGC025H03 FGC026B04 FGC026B08 FGC026G12 FGC028G08 FGC029B05 FGC030G02 FGC031B03 FGC032G07 FGH001C01 FGH001C02 FGH101E06 FGH101F12 FGH102F06 FGH104D07 FGH107D01 FGH110A04 FGH111D10 FGH114D03 FGH114E11 FGH116B11 FGH117D12 FGH119E05 FGH120A07 FGH121B01 FGH123B10 FGH123F06 FGH123F11 FGH127G11 FGH128A02 FGM001E11 FGM003C12 FGM004C07 FGM101F08 FGM102A04 FGM102H03 FGM103A12 FGM103D11 FGM207H03 FGM211A12 FGM213C12 FGM215C07 FGM216C08 FGM218B11 FGM219F03 FGM220E11 FGM221G07 FGM221G12 FGM226B05 FGM230A10 FGM231C12 FGM231F03 FGM231H04 FGM232E11 FGM233A06 FGM237G07 FGM301C01 FGM301F01 FGM301F11 FGM302H01 FGM303F06 FGM303G08 FGM305A11 FGM308D12 FGM309G08 FGM310H03 FGM311H03 FGM318C10 FGM320B05 FGM320B11 FGM320D06 FGM321A05 FGM323H07 FGX001D09 GH01734 GH06285 GH07720 GH17994 GH19396 GH20824 GH24812 GH25037 GH26974 GH28332 GM06950 GM08314 GM15017 GM20563 GM25231 IP16069 IP16169 LD04851 LD07557 LD08210 LD14316 LD15469 LD18451 LD19258 LD20682 LD21126 LD21222 LD21377 LD32840 LD35788 LD35891 LD39221 LD40465 LD43252 LD45471 LD45479 LP03456 LP05147 LP08387 LP08389 LP24420 RE01133 RE01176 RE02248 RE03091 RE03859 RE04594 RE05818 RE06371 RE06574 RE07207 RE07530 RE07587 RE07793 RE08868 RE10386 RE11530 RE12607 RE13432 RE13935 RE15040 RE17444 RE18379 RE21322 RE21363 RE21720 RE22241 RE23638 RE23673 RE24862 RE25205 RE27375 RE27824 RE30844 RE31145 RE31338 RE32949 RE33521 RE35171 RE36357 RE37583 RE39303 RE41752 RE43006 RE43686 RE44144 RE45046 RE46451 RE46617 RE47441 RE47646 RE49149 RE49421 RE49436 RE55140 RE55183 RE59688 RE60620 RE61610 RE63906 RE65066 RE65611 RE66014 RE66082 RE66601 RE68319 RE71375 RE71725 RE72235 RE72439 RE74920 RH01385 RH18458 RH19202 RH23349 RH23535 RH23684 RH23988 RH26614 RH27717 RH30634 RH33835 RH35794 RH36213 RH38780 RH39888 RH41843 RH41940 RH44394 RH47594 RH50779 RH56074 RH56368 RH60594 RH66364 RH72433 RM01001 RM01101 RM01301 RM01501 RM01601 RP01396 RP001001452 RP001005769 RP001007470 RP001009668 RP001012418 RP001012839 RP001015375 RP001017070 RP001018879 RP001020782 RP001022474 RP001023239 RP001023681 RP001023958 RP001024811 RP001025810 RP001025847 RP001031080 RP001036079 RP001037229 RP001044076 RP001047163 RP001050853 RP001055049 RP001055307 SD25434 UT01726 UT01965 UUGC0654 UUGC0797 UUGC0912 UUGC1080
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0024733 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43864
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: RpL10 Qm (FlyBase, 2009-)
Source for database merge of	Source for merge of: Qm anon-EST:Posey179 (Bayraktaroglu, 2000.11.2) Source for merge of: Qm BcDNA:LD24589 (FlyBase, 1996-)
Additional comments	FlyBase Curator comment: This gene has been renamed from 'Qm' to 'RpL10' in order to: i) minimize confusion with the 'qm' gene (FBgn0019662); ii) provide consistent nomenclature for the D. melanogaster ribosomal protein genes; iii) better reflect its orthology with mammalian RPL10. (The gene was originally named 'Qm' in FBrf0101969 based on orthology to the human 'QM' gene. This gene is now known as RPL10 at the HGNC.) (FlyBase, 2009-) "Qm" likely corresponds to "M(3)80". (Marygold et al., 2007) Source for merge of Qm BcDNA:LD24589 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
	Haploinsufficient locus. (Cook et al., 2012) RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Likely Minute gene. (Marygold et al., 2007) Deletions removing Qm but no other cytoplasmic ribosomal protein-encoding genes show Minute phenotypes. (Marygold et al., 2007) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143697 NM_168984 NM_001275304 RefSeq (Proteins) • NP_651954 NP_730773 NP_001262233 DDBJ / EMBL / GenBank • AA820729 AAC16108 AAF45440 AAG22453 AAL48532 AAO39584 AF083289 AGB94926 AY070910 BI163043 BI578369 BT003580 U49721 Entrez Gene - A searchable database of RefSeq genes. • 43864 UniProtKB/Swiss-Prot • O61231
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L10e, conserved site (IPR018255) Ribosomal protein L10e (IPR001197) Ribosomal protein L10e/L16 (IPR016180) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE72235
Linkouts
	BioGRID - A database of protein and genetic interactions • 68678 DroID - A comprehensive database of gene and protein interactions. • FBgn0024733 DRSC - Results from RNAi screens. • FBgn0024733 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024733 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17521-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0024733 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43864 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43864 modMine - Data generated by the modENCODE project. • FBgn0024733
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	anon-EST:Posey179   BcDNA:LD24589   CG17521 (Goshima et al., 2007, Marygold et al., 2007, Keleman et al., 2009.8.5, Perkins et al., 2009, Cammarato et al., 2011) DQM (Nguyen, 1996.2.21, Nguyen-Yue et al., 1997) L10 (Rolls et al., 2007) Qm (Kallappagoudar et al., 2010, Marygold et al., 2007, Beller et al., 2006, Lipatov et al., 2005, Müller et al., 2010, Japanese National Institute of Genetics, 2012.5.21) RpL10 (Ashburner and Marygold, 2004.7.2, Goshima et al., 2007, Marygold et al., 2007, Cook et al., 2012) Rp L10 (Alonso and Santaren, 2006)
Name Synonym	Qm (Lipatov et al., 2005, Cammarato et al., 2011) Ribosomal protein L10 (Ashburner and Marygold, 2004.7.2, ) Ribosome RL10 (Saurin et al., 2001)
Secondary FlyBase IDs
	FBan0017521 FBgn0026279 FBgn0064923
References ( 43 )
Generate a list of	All references relating to this gene ( 43 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 8 ) Review  ( 1 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 3 ) Stock list  ( 1 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 2 )
	Cook et al., 2012, Genome Biol. 13(3): R21 The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066] Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...