• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG2701

General Information
Symbol	Dmel\CG2701	Species	D. melanogaster
Name		Annotation symbol	CG2701
Feature type	protein_coding_gene	FlyBase ID	FBgn0024973
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	EG:95B7.9
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	3B3-3B3	Sequence location	X:2,611,671..2,614,360 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG2701 (FBgn0024973). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: UBA-like; Ubiquitin system component Cue. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626169_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG2701. Gene sequence location is X:2611671..2614360.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 3B3-3B3   Limits computationally determined from genome sequence between P{EP}EP1362 and P{EP}dncEP1395
Experimentally Determined Cytological Location
Cytogenetic map Notes References 3B3-3B4     (Lin and Wolfner, 1989)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG2701 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43 Gene model reviewed during 5.50 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG2701-RA FBtr0070498  NM_130669   2425   735
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG2701-PA   FBpp0070475   83.1   735   4.57     NP_570025   AAF45814
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ubiquitin system component Cue (IPR003892) UBA-like (IPR009060)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA820709   AE014298 AAF45814   AI109253   AI405713   AI455501   AI518726   AI541696   AI543293   AL021728 CAA16821   AY051706 AAK93130   BF492594   BF492595   BF497407   BF503049   BI230336   BI232720   BI232852   BI239665   BI353148   BI569873   BI585740   BI587698   BI588533   BI608041   BI609202   BI615161   BI615401   BI625836   BI641282   CK657324   CO297461   EC064471   EL873409   EL873410   EL875462   EL875463   EL875574   EL875575
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O76912
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    167.05 Larval Midgut    110.6 Larval Hindgut    141.5 Larval Malpighian Tubules    131.3 Larval Fat Body    115.6 Larval Salivary Gland    173.4 Larval Trachea    106.375 Larval Carcass    104.75 Adult Head    123.6 Adult Eye    170.8 Adult Brain    205.5 Adult Thoracic-Abdominal Ganglion    198.8 Adult Crop    124.7 Adult Midgut    97.9 Adult Hindgut    126 Adult Malpighian Tubules    166.8 Adult Fat Body    137.4 Adult Salivary Gland    147.4 Adult Heart    119.575 Adult VirginFemale Spermatheca    135 Adult InseminatedFemale Spermatheca    129.1 Adult Ovary    133.8 Adult Testis    77.4 Adult Male Accessory Gland    236.7 Adult Carcass    140.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    123.6   NA  Eye    170.8   NA  Brain    205.5   167.05  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    198.8   NA  Crop    124.7   110.6  Midgut    97.9   141.5  Hindgut    126   131.3  Malpighian Tubules    166.8   115.6  Fat Body    137.4   173.4  Salivary Gland    147.4   NA  Heart    119.575   106.375  Trachea    NA   NA  VirginFemale Spermatheca    135   NA  InseminatedFemale Spermatheca    129.1   NA  Ovary    133.8   NA  Testis    77.4   NA  Male Accessory Gland    236.7   104.75  Carcass    140.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    12 central nervous system, pupae P8    7 head, virgin 1-day female    6 head, virgin 4-day female    7 head, virgin 20-day female    9 head, mated 1-day female    6 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    11 head, mated 4-day male    8 head, mated 20-day male    10 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    7 digestive system, 4-day adult    7 digestive system, 20-day adult    8 fat body, larvae L3 wandering    4 fat body, white prepupae    4 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    6 ovary, virgin 4-day female    14 ovary, mated 4-day female    12 testis, mated 4-day male    18 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr    29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr    27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day    26 adult male 30day    26 adult female 01day    27 adult female 05day    27 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (42) embryo 02-04hr  (29) embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr  (29) embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr  (27) pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day  26 adult male 30day  26 adult female 01day  (27) adult female 05day  (27) adult female 30day  (30) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr    29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr    27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day    26 adult male 30day    26 adult female 01day    27 adult female 05day    27 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr    29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr    27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day    26 adult male 30day    26 adult female 01day    27 adult female 05day    27 adult female 30day    30 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr    29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr    27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day    26 adult male 30day    26 adult female 01day    27 adult female 05day    27 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (42) embryo 02-04hr  29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr  29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr  27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day  26 adult male 30day  26 adult female 01day  27 adult female 05day  27 adult female 30day  30 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr    29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr    27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day    26 adult male 30day    26 adult female 01day    27 adult female 05day    27 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    42 embryo 02-04hr    29 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    21 embryo 10-12hr    29 embryo 12-14hr    16 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    13 embryo 20-22hr    13 embryo 22-24hr    11 larva L1    19 larva L2    17 larva L3 12hr old    17 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    18 white prepupae new    17 white prepupae 12hr    20 white prepupae 24hr    27 pupae 2d postWPP    18 pupae 3d postWPP    12 pupae 4d postWPP    15 adult male 01day    21 adult male 05day    26 adult male 30day    26 adult female 01day    27 adult female 05day    27 adult female 30day    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    34 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21  (34) wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    34 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    34 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    34 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21  (34) wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    34 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    21 embryonic 1182-4H    19 embryonic GM2    12 embryonic Kc167    18 embryonic S1    23 embryonic S3    16 leg disc CME L1    17 wing disc CME-W2    12 wing disc ML-DmD8    12 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    34 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    19 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    11 CNS ML-DmBG2-c2    15 tumorous blood cells mbn2    8 ovary fGS/OSS    14 ovary OSC    11 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    7 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    8 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • LD24566 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024973 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2701-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG2701GD9811 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG2701 Class Mutagen Stocks Known lesion CG2701EY04983 1 -- CG2701NP6015 1 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG2701 Class Mutagen Stocks Known lesion CG2701GD9811 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG2701KK107686 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG2701t1.8 in vitro construct - genomic fragment 0 Yes CG2701t4.6 in vitro construct - genomic fragment 0 Yes CG2701t6.4 in vitro construct - genomic fragment 0 Yes CG2701t8.1 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9811} NA P{KK107686} NA characterization construct P{fs(1)Ya+t8.1} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system P{GawB}CG2701NP6015 No insertion of mobile activating element P{EPgy2}CG2701EY04983 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG2701 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57792 DroID - A comprehensive database of gene and protein interactions. • FBgn0024973 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31261
Orthologs
OrthoDB Orthologs (40) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69343H Dipteran inclusive ortholog search EOG65MNDN Insect inclusive ortholog search EOG676HV8 Arthropod inclusive ortholog search EOG6FTTFN Metazoa inclusive ortholog search EOG628DTM
Orthologs in Drosophila Species (EOG69343H)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG2701     Drosophila sechellia   Dsec\GM18858 Y   Drosophila erecta   Dere\GG18610 Y   Drosophila yakuba   Dyak\GE16925 Y   Drosophila ananassae   Dana\GF22485 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA15436 Y   Drosophila persimilis   Dper\GL19809 Y   Drosophila willistoni   Dwil\GK10246 Y   Drosophila virilis   Dvir\GJ18535 Y   Drosophila mojavensis   Dmoj\GI14728 Y   Drosophila grimshawi   Dgri\GH11942 Y
Orthologs in non-Drosophila Dipterans (EOG65MNDN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014679   Anopheles gambiae Malaria mosquito  Agam\AGAP000428   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ018292
Orthologs in non-Dipteran Insects (EOG676HV8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB54120   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG023472   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22195   Atta cephalotes Leafcutter ant  Acep\ACEP13639   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20693   Linepithema humile Argentine ant  Lhum\LH20483   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20342   Solenopsis invicta Red fire ant  Sinv\SINV24193   Acyrthosiphon pisum Pea aphid  Apim\ACYPI073785   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009923   Acyrthosiphon pisum Pea aphid  Apim\ACYPI065061   Acyrthosiphon pisum Pea aphid  Apim\ACYPI086905   Bombyx mori Silkmoth  Bmor\BGIBMGA007346   Pediculus humanus Human body louse  Phum\PHUM467450   Tribolium castaneum Red flour beetle  Tcas\TC005589
Orthologs in non-Insect Arthropods (EOG6FTTFN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Cyt b   Ixodes scapularis Deer tick  Isca\ISCW001972
Orthologs in non-Arthropod Metazoa (EOG628DTM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013136gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013953gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019786gn   Danio rerio Zebrafish  Drer\CH211-188G24.1   Xenopus tropicalis Western clawed frog  Xtro\ascc2   Gallus gallus Domestic chicken  Ggal\ASCC2   Mus musculus House mouse  Mmus\Ascc2   Rattus norvegicus Norway rat  Rnor\Ascc2   Homo sapiens Human  Hsap\ASCC2
Human Orthologs (1)
Gene OMIM HGNC Hsap\ASCC2
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM18858 Drosophila erecta Dere\GG18610 Drosophila yakuba Dyak\GE16925 Drosophila ananassae Dana\GF22485 Drosophila pseudoobscura pseudoobscura Dpse\GA15436 Drosophila persimilis Dper\GL19809 Drosophila willistoni Dwil\GK10246 Drosophila virilis Dvir\GJ18535 Drosophila mojavensis Dmoj\GI14728 Drosophila grimshawi Dgri\GH11942
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	15778 y1 P{EPgy2}CG2701EY04983 w67c23
Kyoto	105074 y* P{GawB}CG2701NP6015 w* / FM7c
VDRC	v106635 P{KK107686}VIE-260B v25432 w1118; P{GD9811}v25432 v25433 w1118; P{GD9811}v25433
Genomic Clones ( 1 )
	BACR30B01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 30 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24566
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT11569 AT18951 GH08386 GH25829 GM22472 LD38429 LP23525 RE10128 RE28840 RE28979 RE36225 RH02044 RH12169 RH13955 RH25385 RH28547 RH29886 RH44719 RH45016 RH66332 SD06716 SD24509
Other clones	83376 AT01081 EK217028 IP05267 IP05467 IP05567 SD10010
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0024973 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31261
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: EG:95B7.9 CG2701 (Deng, 1999.11)
Source for database merge of	Source for merge of: EG:95B7.9 anon-3Bd (Gatt and Ashburner, 2000.2.3)
Additional comments
Other Comments
	Transcription unit identified during molecular analysis of the fs(1)Ya gene region. Relative position to fs(1)Ya and genetic and molecular maps of the gene region suggest transcript I or II might be l(1)3Bd. (Lin and Wolfner, 1989)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130669 RefSeq (Proteins) • NP_570025 DDBJ / EMBL / GenBank • AA820709 AAF45814 AAK93130 AI109253 AI455501 AL021728 AY051706 CAA16821 Entrez Gene - A searchable database of RefSeq genes. • 31261 UniProtKB/TrEMBL • O76912
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ubiquitin system component Cue (IPR003892) UBA-like (IPR009060) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD24566
Linkouts
	BioGRID - A database of protein and genetic interactions • 57792 DroID - A comprehensive database of gene and protein interactions. • FBgn0024973 DRSC - Results from RNAi screens. • FBgn0024973 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0024973 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2701-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0024973 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31261 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31261 modMine - Data generated by the modENCODE project. • FBgn0024973
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-3Bd (Benos et al., 2001, ) CG2701 (Hollien and Weissman, 2006, Keleman et al., 2009.8.5) EG:95B7.9 (Gatt and Ashburner, 2000.2.3, Giot et al., 2003, ) II (Lin and Wolfner, 1989)
Name Synonym	Coding Region II (Lin and Wolfner, 1989) transcript II (King and Lin, 1999)
Secondary FlyBase IDs
	FBgn0020598
References ( 20 )
Research paper	Benos et al., 2001, Genome Res. 11(5): 710--730 From First Base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. [FBrf0135823] King and Lin, 1999, Development 126(9): 1833--1844 Somatic signaling mediated by fs(1)Yb is essential for germline stem cell maintenance during Drosophila oogenesis. [FBrf0108421] Lin and Wolfner, 1989, Mol. Gen. Genet. 215(9): 257--265 Cloning and analysis of fs(1)Ya, a maternal effect gene required for the initiation of Drosophila embryogenesis. [FBrf0050562]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 29. Summary of A-to-I RNA Editing Sites Discovered. [FBrf0213715] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Hollien and Weissman, 2006, Science 313(5783): [FBrf0199122] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] Benos, 2000.12.13, FlyBase error report on Wed Dec 13 14:35:56 2000. FlyBase error report on Wed Dec 13 14:35:56 2000. [FBrf0133222] Gatt and Ashburner, 2000.2.3, Gene merges in X tip with a pc. Gene merges in X tip with a pc. [FBrf0125090]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Curated genome annotation	Deng, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0128757]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]