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Gene Dmel\und

General Information
Symbol	Dmel\und	Species	D. melanogaster
Name	uninitiated	Annotation symbol	CG4008
Feature type	protein_coding_gene	FlyBase ID	FBgn0025117
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	30C7-30C7	Sequence location	2L:9,763,345..9,765,338 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene uninitiated is referred to in FlyBase by the symbol Dmel\und (CG4008, FBgn0025117). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis; cellular process. 10 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; eye; trichogen cell; eye photoreceptor cell; wing; ommatidium. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase M24, methionine aminopeptidase; Peptidase M24, structural domain; Peptidase M24A, methionine aminopeptidase, subfamily 2; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1627059_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of und. Gene sequence location is 2L:9763345..9765338.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN22005 HFA03629
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 30C7-30C7   Limits computationally determined from genome sequence between P{lacW}zf30Ck02506&P{EP}undEP424 and P{lacW}l(2)k06416k06416&P{lacW}sopk04603
Experimentally Determined Cytological Location
Cytogenetic map Notes References 30C6-30C7     (Cutforth, 1998.2.18)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\und for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) und-RA FBtr0079866  NM_058025   1772   448
Additional Transcript Data & Comments
Reported size (kB)	1.562 (longest cDNA) (Cutforth and Gaul, 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein und-PA   FBpp0079462   49.8   448   6.67     NP_477373   AAF52807
Additional Polypeptide Data & Comments
Reported size (kDa)	448 (aa) (Cutforth and Gaul, 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase M24, structural domain (IPR000994) Peptidase M24, methionine aminopeptidase (IPR001714) Peptidase M24A, methionine aminopeptidase, subfamily 2 (IPR002468) Winged helix-turn-helix transcription repressor DNA-binding (IPR011991) MEROPS - An information resource for peptidases and the proteins that inhibit them • M24.002
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567214   AA695120   AA698591   AA802216   AA950339   AE014134 AAF52807   AC007291   AF049912 AAC05144   AI061898   AI063365   AI107654   AI107754   AI108758   AI260666   AI541698   AI544297   AI944881   AQ026000   AW940123   AY047525 AAK77257   AY433143   BF485612   BF485832   BF486511   BF486530   BF486707   BF493792   BF495117   BF497447   BF499707   BF499998   BF502641   BF502741   BG632870   BG640448   BI213274   BI216363   BI231379   BI235160   BI352602   BI354811   BI482785   BI568309   BI568892   BI568893   BI570076   BI584209   BI587070   BI589932   BI592200   BI606369   BI606491   BI610490   BI616353   BI617695   BI624570   BI626100   BI627240   BI635580   BI637782   BI638969   BP543555   BP543556   BP557072   BP557073   BQ103281   CA807582   CO152922   CO176985   CO272192   CO272200   CO281256   CO287022   CO295278   CO301247   CO301271   CO304206   CO308211   CO308881   CO312081   CO313396   CO326686   CZ470862   EC051312   EC051313   EC051852   EC052377   EC052783   EC053402   EC053803   EC054361   EC056049   EC058210   EC061792   EC065737   EC068784   EC071801   EC074200   EC076532   EC076928   EC077741   EC202118   EC211564   EC213984   EC221862   EC222543   EC224697   EC230122   EC232303   EC248362   EC249539   EC263606   EL874178   EL874293   EL886343   EL886453   EL886569   EL886673   EV575195   EV575289   EV586849   EV588281   EV588680   EV591223   EV591701   EV591783   EV591923   EV592050   EV598369   EV598720   GH755729   GH832906   GH908477
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O61540 Q9VL89
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
expression microarray Stage Tissue/Position (including subcellular localization) Reference adult stage   eye   (Xu et al., 2004) in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 5   organism   (Cutforth and Gaul, 1999) Comment:early stage 5 gastrula stage   anterior embryonic/larval midgut   (Cutforth and Gaul, 1999) mesoderm   (Cutforth and Gaul, 1999) posterior embryonic/larval midgut   (Cutforth and Gaul, 1999) embryonic stage 8   midgut constriction   (Cutforth and Gaul, 1999) third instar larval stage   eye-antennal disc | ubiquitous   (Cutforth and Gaul, 1999) embryonic/larval digestive system   (Cutforth and Gaul, 1999)
Additional Descriptive Data
	Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads. (Xu et al., 2004)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010) day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0025117    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0025117 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0025117 expression level Developmental Stage   Expression Level embryo 00-02hr    13109 embryo 02-04hr    5598 embryo 04-06hr    8598 embryo 06-08hr    11315 embryo 08-10hr    11144 embryo 10-12hr    11419 embryo 12-14hr    7632 embryo 14-16hr    8629 embryo 16-18hr    5835 embryo 18-20hr    5442 embryo 20-22hr    6357 embryo 22-24hr    6164 larva L1    14622 larva L2    8870 larva L3 12hr old    6778 larva L3 puffstage 1-2    5715 larva L3 puffstage 3-6    7628 larva L3 puffstage 7-9    9411 white prepupae new    9892 white prepupae 12hr    9078 white prepupae 24hr    9360 pupae 2d postWPP    8972 pupae 3d postWPP    7040 pupae 4d postWPP    10418 adult male 01day    9279 adult male 05day    10796 adult male 30day    11847 adult female 01day    13454 adult female 05day    12817 adult female 30day    13304 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13109) embryo 02-04hr  (5598) embryo 04-06hr  (8598) embryo 06-08hr  (11315) embryo 08-10hr  (11144) embryo 10-12hr  (11419) embryo 12-14hr  (7632) embryo 14-16hr  (8629) embryo 16-18hr  (5835) embryo 18-20hr  (5442) embryo 20-22hr  (6357) embryo 22-24hr  (6164) larva L1  (14622) larva L2  (8870) larva L3 12hr old  (6778) larva L3 puffstage 1-2  (5715) larva L3 puffstage 3-6  (7628) larva L3 puffstage 7-9  (9411) white prepupae new  (9892) white prepupae 12hr  (9078) white prepupae 24hr  (9360) pupae 2d postWPP  (8972) pupae 3d postWPP  (7040) pupae 4d postWPP  (10418) adult male 01day  (9279) adult male 05day  (10796) adult male 30day  (11847) adult female 01day  (13454) adult female 05day  (12817) adult female 30day  (13304) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13109) embryo 02-04hr  (5598) embryo 04-06hr  (8598) embryo 06-08hr  (11315) embryo 08-10hr  (11144) embryo 10-12hr  (11419) embryo 12-14hr  (7632) embryo 14-16hr  (8629) embryo 16-18hr  (5835) embryo 18-20hr  (5442) embryo 20-22hr  (6357) embryo 22-24hr  (6164) larva L1  (14622) larva L2  (8870) larva L3 12hr old  (6778) larva L3 puffstage 1-2  (5715) larva L3 puffstage 3-6  (7628) larva L3 puffstage 7-9  (9411) white prepupae new  (9892) white prepupae 12hr  (9078) white prepupae 24hr  (9360) pupae 2d postWPP  (8972) pupae 3d postWPP  (7040) pupae 4d postWPP  (10418) adult male 01day  (9279) adult male 05day  (10796) adult male 30day  (11847) adult female 01day  (13454) adult female 05day  (12817) adult female 30day  (13304) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (13109) embryo 02-04hr    5598 embryo 04-06hr    8598 embryo 06-08hr  (11315) embryo 08-10hr  (11144) embryo 10-12hr  (11419) embryo 12-14hr    7632 embryo 14-16hr    8629 embryo 16-18hr    5835 embryo 18-20hr    5442 embryo 20-22hr    6357 embryo 22-24hr    6164 larva L1  (14622) larva L2    8870 larva L3 12hr old    6778 larva L3 puffstage 1-2    5715 larva L3 puffstage 3-6    7628 larva L3 puffstage 7-9    9411 white prepupae new    9892 white prepupae 12hr    9078 white prepupae 24hr    9360 pupae 2d postWPP    8972 pupae 3d postWPP    7040 pupae 4d postWPP  10418 adult male 01day    9279 adult male 05day  (10796) adult male 30day  (11847) adult female 01day  (13454) adult female 05day  (12817) adult female 30day  (13304) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13109 embryo 02-04hr    5598 embryo 04-06hr    8598 embryo 06-08hr    11315 embryo 08-10hr    11144 embryo 10-12hr    11419 embryo 12-14hr    7632 embryo 14-16hr    8629 embryo 16-18hr    5835 embryo 18-20hr    5442 embryo 20-22hr    6357 embryo 22-24hr    6164 larva L1    14622 larva L2    8870 larva L3 12hr old    6778 larva L3 puffstage 1-2    5715 larva L3 puffstage 3-6    7628 larva L3 puffstage 7-9    9411 white prepupae new    9892 white prepupae 12hr    9078 white prepupae 24hr    9360 pupae 2d postWPP    8972 pupae 3d postWPP    7040 pupae 4d postWPP    10418 adult male 01day    9279 adult male 05day    10796 adult male 30day    11847 adult female 01day    13454 adult female 05day    12817 adult female 30day    13304 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0025117 expression level Developmental Stage   Expression Level embryo 00-02hr    13109 embryo 02-04hr    5598 embryo 04-06hr    8598 embryo 06-08hr    11315 embryo 08-10hr    11144 embryo 10-12hr    11419 embryo 12-14hr    7632 embryo 14-16hr    8629 embryo 16-18hr    5835 embryo 18-20hr    5442 embryo 20-22hr    6357 embryo 22-24hr    6164 larva L1    14622 larva L2    8870 larva L3 12hr old    6778 larva L3 puffstage 1-2    5715 larva L3 puffstage 3-6    7628 larva L3 puffstage 7-9    9411 white prepupae new    9892 white prepupae 12hr    9078 white prepupae 24hr    9360 pupae 2d postWPP    8972 pupae 3d postWPP    7040 pupae 4d postWPP    10418 adult male 01day    9279 adult male 05day    10796 adult male 30day    11847 adult female 01day    13454 adult female 05day    12817 adult female 30day    13304 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13109) embryo 02-04hr  (5598) embryo 04-06hr  (8598) embryo 06-08hr  (11315) embryo 08-10hr  (11144) embryo 10-12hr  (11419) embryo 12-14hr  (7632) embryo 14-16hr  (8629) embryo 16-18hr  (5835) embryo 18-20hr  (5442) embryo 20-22hr  (6357) embryo 22-24hr  (6164) larva L1  (14622) larva L2  (8870) larva L3 12hr old  (6778) larva L3 puffstage 1-2  (5715) larva L3 puffstage 3-6  (7628) larva L3 puffstage 7-9  (9411) white prepupae new  (9892) white prepupae 12hr  (9078) white prepupae 24hr  (9360) pupae 2d postWPP  (8972) pupae 3d postWPP  (7040) pupae 4d postWPP  (10418) adult male 01day  (9279) adult male 05day  (10796) adult male 30day  (11847) adult female 01day  (13454) adult female 05day  (12817) adult female 30day  (13304) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13109) embryo 02-04hr  (5598) embryo 04-06hr  (8598) embryo 06-08hr  (11315) embryo 08-10hr  (11144) embryo 10-12hr  (11419) embryo 12-14hr  (7632) embryo 14-16hr  (8629) embryo 16-18hr  (5835) embryo 18-20hr  (5442) embryo 20-22hr  (6357) embryo 22-24hr  (6164) larva L1  (14622) larva L2  (8870) larva L3 12hr old  (6778) larva L3 puffstage 1-2  (5715) larva L3 puffstage 3-6  (7628) larva L3 puffstage 7-9  (9411) white prepupae new  (9892) white prepupae 12hr  (9078) white prepupae 24hr  (9360) pupae 2d postWPP  (8972) pupae 3d postWPP  (7040) pupae 4d postWPP  (10418) adult male 01day  (9279) adult male 05day  (10796) adult male 30day  (11847) adult female 01day  (13454) adult female 05day  (12817) adult female 30day  (13304) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  13109 embryo 02-04hr    5598 embryo 04-06hr    8598 embryo 06-08hr  11315 embryo 08-10hr  11144 embryo 10-12hr  11419 embryo 12-14hr    7632 embryo 14-16hr    8629 embryo 16-18hr    5835 embryo 18-20hr    5442 embryo 20-22hr    6357 embryo 22-24hr    6164 larva L1  14622 larva L2    8870 larva L3 12hr old    6778 larva L3 puffstage 1-2    5715 larva L3 puffstage 3-6    7628 larva L3 puffstage 7-9    9411 white prepupae new    9892 white prepupae 12hr    9078 white prepupae 24hr    9360 pupae 2d postWPP    8972 pupae 3d postWPP    7040 pupae 4d postWPP  10418 adult male 01day    9279 adult male 05day  10796 adult male 30day  11847 adult female 01day  13454 adult female 05day  12817 adult female 30day  13304 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13109 embryo 02-04hr    5598 embryo 04-06hr    8598 embryo 06-08hr    11315 embryo 08-10hr    11144 embryo 10-12hr    11419 embryo 12-14hr    7632 embryo 14-16hr    8629 embryo 16-18hr    5835 embryo 18-20hr    5442 embryo 20-22hr    6357 embryo 22-24hr    6164 larva L1    14622 larva L2    8870 larva L3 12hr old    6778 larva L3 puffstage 1-2    5715 larva L3 puffstage 3-6    7628 larva L3 puffstage 7-9    9411 white prepupae new    9892 white prepupae 12hr    9078 white prepupae 24hr    9360 pupae 2d postWPP    8972 pupae 3d postWPP    7040 pupae 4d postWPP    10418 adult male 01day    9279 adult male 05day    10796 adult male 30day    11847 adult female 01day    13454 adult female 05day    12817 adult female 30day    13304 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0025117    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0025117 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0025117 expression level Tissue   Expression Level Larval Central Nervous System    1009.925 Larval Midgut    681.3 Larval Hindgut    1210.9 Larval Malpighian Tubules    1233.2 Larval Fat Body    1160.5 Larval Salivary Gland    836.5 Larval Trachea    1628.425 Larval Carcass    1383.525 Adult Head    659.6 Adult Eye    963.075 Adult Brain    528.9 Adult Thoracic-Abdominal Ganglion    692.8 Adult Crop    1364.8 Adult Midgut    837.3 Adult Hindgut    1058.8 Adult Malpighian Tubules    953 Adult Fat Body    833.1 Adult Salivary Gland    704.1 Adult Heart    1077.6 Adult VirginFemale Spermatheca    1463.8 Adult InseminatedFemale Spermatheca    1454.5 Adult Ovary    1374.6 Adult Testis    1293.7 Adult Male Accessory Gland    682.1 Adult Carcass    780.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1009.925) Larval Midgut  (681.3) Larval Hindgut  (1210.9) Larval Malpighian Tubules  (1233.2) Larval Fat Body  (1160.5) Larval Salivary Gland  (836.5) Larval Trachea  (1628.425) Larval Carcass  (1383.525) Adult Head  (659.6) Adult Eye  (963.075) Adult Brain  528.9 Adult Thoracic-Abdominal Ganglion  (692.8) Adult Crop  (1364.8) Adult Midgut  (837.3) Adult Hindgut  (1058.8) Adult Malpighian Tubules  (953) Adult Fat Body  (833.1) Adult Salivary Gland  (704.1) Adult Heart  (1077.6) Adult VirginFemale Spermatheca  (1463.8) Adult InseminatedFemale Spermatheca  (1454.5) Adult Ovary  (1374.6) Adult Testis  (1293.7) Adult Male Accessory Gland  (682.1) Adult Carcass  (780.7) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1009.925 Larval Midgut    681.3 Larval Hindgut  (1210.9) Larval Malpighian Tubules  (1233.2) Larval Fat Body  (1160.5) Larval Salivary Gland    836.5 Larval Trachea  (1628.425) Larval Carcass  (1383.525) Adult Head    659.6 Adult Eye    963.075 Adult Brain    528.9 Adult Thoracic-Abdominal Ganglion    692.8 Adult Crop  (1364.8) Adult Midgut    837.3 Adult Hindgut  1058.8 Adult Malpighian Tubules    953 Adult Fat Body    833.1 Adult Salivary Gland    704.1 Adult Heart  1077.6 Adult VirginFemale Spermatheca  (1463.8) Adult InseminatedFemale Spermatheca  (1454.5) Adult Ovary  (1374.6) Adult Testis  (1293.7) Adult Male Accessory Gland    682.1 Adult Carcass    780.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1009.925 Larval Midgut    681.3 Larval Hindgut    1210.9 Larval Malpighian Tubules    1233.2 Larval Fat Body    1160.5 Larval Salivary Gland    836.5 Larval Trachea    1628.425 Larval Carcass    1383.525 Adult Head    659.6 Adult Eye    963.075 Adult Brain    528.9 Adult Thoracic-Abdominal Ganglion    692.8 Adult Crop    1364.8 Adult Midgut    837.3 Adult Hindgut    1058.8 Adult Malpighian Tubules    953 Adult Fat Body    833.1 Adult Salivary Gland    704.1 Adult Heart    1077.6 Adult VirginFemale Spermatheca    1463.8 Adult InseminatedFemale Spermatheca    1454.5 Adult Ovary    1374.6 Adult Testis    1293.7 Adult Male Accessory Gland    682.1 Adult Carcass    780.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0025117 expression level Tissue   Expression Level Larval Central Nervous System    1009.925 Larval Midgut    681.3 Larval Hindgut    1210.9 Larval Malpighian Tubules    1233.2 Larval Fat Body    1160.5 Larval Salivary Gland    836.5 Larval Trachea    1628.425 Larval Carcass    1383.525 Adult Head    659.6 Adult Eye    963.075 Adult Brain    528.9 Adult Thoracic-Abdominal Ganglion    692.8 Adult Crop    1364.8 Adult Midgut    837.3 Adult Hindgut    1058.8 Adult Malpighian Tubules    953 Adult Fat Body    833.1 Adult Salivary Gland    704.1 Adult Heart    1077.6 Adult VirginFemale Spermatheca    1463.8 Adult InseminatedFemale Spermatheca    1454.5 Adult Ovary    1374.6 Adult Testis    1293.7 Adult Male Accessory Gland    682.1 Adult Carcass    780.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1009.925) Larval Midgut  681.3 Larval Hindgut  (1210.9) Larval Malpighian Tubules  (1233.2) Larval Fat Body  (1160.5) Larval Salivary Gland  (836.5) Larval Trachea  (1628.425) Larval Carcass  (1383.525) Adult Head  659.6 Adult Eye  (963.075) Adult Brain  528.9 Adult Thoracic-Abdominal Ganglion  692.8 Adult Crop  (1364.8) Adult Midgut  (837.3) Adult Hindgut  (1058.8) Adult Malpighian Tubules  (953) Adult Fat Body  (833.1) Adult Salivary Gland  704.1 Adult Heart  (1077.6) Adult VirginFemale Spermatheca  (1463.8) Adult InseminatedFemale Spermatheca  (1454.5) Adult Ovary  (1374.6) Adult Testis  (1293.7) Adult Male Accessory Gland  682.1 Adult Carcass  780.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1009.925 Larval Midgut    681.3 Larval Hindgut  1210.9 Larval Malpighian Tubules  1233.2 Larval Fat Body  1160.5 Larval Salivary Gland    836.5 Larval Trachea  1628.425 Larval Carcass  1383.525 Adult Head    659.6 Adult Eye    963.075 Adult Brain    528.9 Adult Thoracic-Abdominal Ganglion    692.8 Adult Crop  1364.8 Adult Midgut    837.3 Adult Hindgut  1058.8 Adult Malpighian Tubules    953 Adult Fat Body    833.1 Adult Salivary Gland    704.1 Adult Heart  1077.6 Adult VirginFemale Spermatheca  1463.8 Adult InseminatedFemale Spermatheca  1454.5 Adult Ovary  1374.6 Adult Testis  1293.7 Adult Male Accessory Gland    682.1 Adult Carcass    780.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1009.925 Larval Midgut    681.3 Larval Hindgut    1210.9 Larval Malpighian Tubules    1233.2 Larval Fat Body    1160.5 Larval Salivary Gland    836.5 Larval Trachea    1628.425 Larval Carcass    1383.525 Adult Head    659.6 Adult Eye    963.075 Adult Brain    528.9 Adult Thoracic-Abdominal Ganglion    692.8 Adult Crop    1364.8 Adult Midgut    837.3 Adult Hindgut    1058.8 Adult Malpighian Tubules    953 Adult Fat Body    833.1 Adult Salivary Gland    704.1 Adult Heart    1077.6 Adult VirginFemale Spermatheca    1463.8 Adult InseminatedFemale Spermatheca    1454.5 Adult Ovary    1374.6 Adult Testis    1293.7 Adult Male Accessory Gland    682.1 Adult Carcass    780.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    659.6   NA  Eye    963.075   NA  Brain    528.9   1009.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    692.8   NA  Crop    1364.8   681.3  Midgut    837.3   1210.9  Hindgut    1058.8   1233.2  Malpighian Tubules    953   1160.5  Fat Body    833.1   836.5  Salivary Gland    704.1   NA  Heart    1077.6   1628.425  Trachea    NA   NA  VirginFemale Spermatheca    1463.8   NA  InseminatedFemale Spermatheca    1454.5   NA  Ovary    1374.6   NA  Testis    1293.7   NA  Male Accessory Gland    682.1   1383.525  Carcass    780.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_26
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025117 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4008-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for und Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | recessive undP viable, with Scer\GAL4pnr-MD237 undGD11188 Other Phenotypes Allele planar polarity defective | recessive undP undΔ19 visible, with Scer\GAL4pnr-MD237 undGD11188 visible | recessive undP undΔ11 undΔ18 undΔ34 wild-type und+t4.3 Phenotype manifest in Allele eye undΔ11 undΔ18 undΔ34 undP eye | anterior undΔ11 undP eye | ventral undΔ11 undΔ18 undΔ34 eye photoreceptor cell undΔ19 undP ommatidium undΔ19 undP trichogen cell, with Scer\GAL4pnr-MD237 undGD11188 wing undP wing vein L5 undΔ18 undΔ34
Classical Alleles ( 7 )
For All Classical Alleles Show
Allele of und Class Mutagen Stocks Known lesion undc06617 piggyBac transposase 1 -- undEP424 P-element activity 1 -- undΔ34 MR 1 Yes undP P-element activity 0 Yes undΔ11 Delta2-3 0 -- undΔ18 Delta2-3 0 -- undΔ19 Delta2-3 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of und Class Mutagen Stocks Known lesion undGD11188 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes und+t4.3 in vitro construct - genomic fragment 0 Yes undKK101939 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)30A-C (Cutforth and Gaul, 1999) Df(2L)BSC216 (Christensen and Cook, 2006.8.30) Df(2L)BSC240 (Christensen and Cook, 2006.12.5) Df(2L)Exel6024 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11188} NA P{KK101939} NA characterization construct P{und+t4.3} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}undEP424 NA insertion of enhancer trap P{lacW}l(2)SH0353SH0353 No P{PZ}undP No miscellaneous insertions PBac{PB}undc06617 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
aminopeptidase activity inferred from sequence or structural similarity with UniProtKB:P38062 (FlyBase, 1992-) non-traceable author statement (Cutforth, 1998.2.18) metalloexopeptidase activity inferred from electronic annotation with InterPro:IPR001714, InterPro:IPR002468 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
cellular process inferred from electronic annotation with InterPro:IPR000994 (FlyBase Curators et al., 2004-) proteolysis inferred from electronic annotation with InterPro:IPR001714, InterPro:IPR002468 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions und allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60391 DroID - A comprehensive database of gene and protein interactions. • FBgn0025117 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34294
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22806 Dere\GG10053 Dgri\GH25144 Dmoj\GI20096 Dper\GL18932 Dpse\GA17851 Dsec\GM17682 Dsim\GD23627 Dvir\GJ13491 Dwil\GK24191 Dyak\GE18867
Curated drosophilid orthologs	Dpse\GA17851
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004738-PA Aedes aegypti (mosquito) AGAP008345-PA Anopheles gambiae (mosquito) XP_624161.1 Apis mellifera (honey bee) XP_001945885.1 Acyrthosiphon pisum (pea aphid) At3g59990.1 Arabidopsis thaliana (wall cress) 36909 Batrachochytrium dendrobatidis (chytrid fungus) 124163 Branchiostoma floridae (lancelet) BGIBMGA009963-PA Bombyx mori (silk worm) ENSBTAP00000026568 Bos taurus (bovine) CAL0002793 Candida albicans (a form of yeast) CN02395 Caenorhabditis brenneri (small nematode) CBP03339 Caenorhabditis briggsae (nematode) CE24146 Caenorhabditis elegans (worm) ENSCAFP00000009531 Canis familiaris (dog) CAGL0G03641g Candida glabrata (haploid yeast) Chro.20263 Cryptosporidium hominis (obligate parasite) ENSCINP00000011313 Ciona intestinalis (sea squirt) JA09885 Caenorhabditis japonica (nematode) CMP247C Cyanidioschyzon merolae (red alga) cn07191 Cryptococcus neoformans (yeast-like fungus) cgd2_2480 Cryptosporidium parvum (protozoan parasite) CPIJ020069 Culex pipens (mosquito) ENSCPOP00000013987 Cavia porcellus (guinea pig) 120712 Chlamidomonas reinhardtii (green alga) RP28278 Caenorhabditis remanei (nematode) ENSCSAVP00000012918 Ciona savignyi (sedentary tunicate) 173347 Capitella spl (polychaete worm) DDB0190923 Dictyostelium discoideum (amoeba) DEHA2C03894g Debaryomyces Hansenii (yeast) 57172 Daphnia pulex (daphnia) ENSDARP00000003646 Danio rerio (zebra fish) ENSECAP00000013236 Equus caballus (horse) XP_651539 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000006033 Gymnopilus aculeatus (mushroom) ENSGALP00000018537 Gallus gallus (chicken) GL50803_86600 Giardia lamblia (flagellated protozoan) 65192 Hypsipyla robusta (cedar shoot borer) ENSP00000325312 Homo sapiens (human) ISCW011848-PA Ixodes scapularis (deer tick) KLLA0E06887g Kluyveromyces lactis (yeast) 179055 Lottia gigantea (owl limpet) LmjF21.0840 Leishmania major (virus) 37121 Monocosta brevicollis (choanoflagellate) ENSMODP00000010154 Monodelphis domestica (gray opossum) ENSMMUP00000018164 Macaca mulatta (rhesus monkey) ENSMUSP00000048285 Mus musculus (house mouse) 181577 Nematostella vectensis (starlet anemone) XP_001600756.1 Nasonia vitripennis (wasp) ENSOANP00000005136 Ornithorynchus anatinus (platypus) ENSORLP00000020836 Oryzias latipes (japanese killifish) LOC_Os12g43370.1 Oryza sativa (asian rice) 27405 Ostreococcus tauri (green alga) PF14_0327 Plasmodium falciparum (protozoal parasite) PHUM000018-PA Pediculus humanus (human body louse) PP21335 Pristionchus pacificus (nematode) 203982 Physcomitrella patens (moss) ENSPPYP00000005526 Pongo pygmaeus (orangutan) 71370 Phytophthora ramorum (sudden oak death pathogen) 109386 Phytophthora sojae (root rot pathogen) 198596 Populus trichocarpa (black cottonwood) ENSPTRP00000009029 Pan troglodytes (chimpanzee) PVX_084805 Plasmodium vivax (protozoal parasite) ENSRNOP00000021149 Rattus norvegicus (norway rat) 4764684 Sorghum bicolor (sorghum) YBL091C Saccharomyces cerevisiae (budding yeast) Smp_011120 Schistosoma mansoni (trematode parasite) SPBC14C8.03 Schizosaccharomyces pombe (fission yeast) XP_780497.2 Strongylocentrotus purpuratus (purple sea urchin) 61709 Trichoplax adhaerens (metazoa) TA18485 Theileria annulata (apicomplexan parasite) XP_969150.1 Tribolium castaneum (red flour beetle) Tc00.1047053506457.10 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053509693.50 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000001034 Tetraodon nigroviridis (green spotted pufferfish) TP03_0593 Theileria parva (parasitic protozoan) 24414 Thalassiosira pseudonana (marine diatom) ENSTRUP00000038362 Takifugu rubripes (pufferfish Takifugu) 3814.m00912 Tetrahymena thermophila (ciliate protozoa) 91003.m00121 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000020290 Xenopus tropicalis (frog) YALI0D05159g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV17109 LH12846 ISCW011848 FBgn0236248 FBgn0226153 FBgn0200715 FBgn0195004 FBgn0172590 JGI_V11_57172 FBgn0077860 FBgn0156533 FBgn0142832 FBgn0132599 FBgn0102365 FBgn0099800 FBgn0098354 CPIJ011945 CPIJ020069 BGIBMGA009963 ACYPI004880 GB13458 AGAP008345 AAEL004738 PB23795 PHUM576050 GLEAN_06844
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	6297 undΔ34/CyO 17168 w1118; P{EP}undEP424
Harvard	- PBac{PB}undc06617
VDRC	v21774 w1118; P{GD11188}v21774 v21772 w1118; P{GD11188}v21772/TM3
Genomic Clones ( 1 )
	BACR02I05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 119 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH03119
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02144 AT03951 AT11619 AT14339 AT14785 AT18436 AT18551 AT19541 AT19886 AT20837 AT20856 AT21211 GH05454 GH05594 GH07992 GH15217 GM01349 GM02170 GM04033 GM20002 GM28363 HL04989 LD28864 LD34959 LP04619 RE18641 RE21439 RE23480 RE30971 RE65543 RH02324 RH03457 RH09836 RH15981 RH23208 RH27338 RH39729 RH46276 RH48106 RH64151 RH66636 RH68496 RH72747 RH72990 SD06718 SD10796 SD11467 SD16968 SD19857 SD21379
Other clones	7813 7961 34624 39437 45841 57987 58087 99836 104603 105709 106835 119420 122878 153470 156670 286273 CK01.15D.D10 CK01.64A.B12 Dmel_dig_018494_0717_1079 Dmel_dig_018692_0722_0989 Dmel_neb_000181_0183_0297 Dmel_neb_001349_0162_0349 Dmel_neb_002146_0421_3596 Dmel_neb_011712_0650_1321 Dmel_neb_012899_0098_2890 Dmel_neb_013004_0390_0620 Dmel_neb_013174_0915_1392 Dmel_neb_014422_0442_1510 Dmel_neb_014460_0639_2812 Dmel_neb_016188_0910_3138 EC051312 EC051313 EC051852 EC052377 EC052783 EC053402 EC053803 EC054361 EC056049 EK052040 EK064639 EK106156 EK106214 EK156310 EK180535 EK180617 EK209318 EK227845 EK232517 EK244113 EK257017 EK259560 EN00826 EP04441 ESG018c.E21.1_E02 FGC021B03 FGM307B08 IP14216 IP14316 IP17645 IP17745 IP17845 IP17945 RH01165 RP003148773 RP003220357 RP003495116 UUGC0684
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0025117 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34294
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Weak und mutations cause ommatidial rotation defects, loss of ventral tissue in the eye and wing vein defects. Stronger alleles impair tissue growth. (Cutforth and Gaul, 1999)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_058025 RefSeq (Proteins) • NP_477373 DDBJ / EMBL / GenBank • AAC05144 AAF52807 AAK77257 AC007291 AF049912 AI063365 AI944881 AQ026000 AW940123 AY047525 CZ470862 Entrez Gene - A searchable database of RefSeq genes. • 34294 UniProtKB/TrEMBL • O61540 Q9VL89
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase M24, structural domain (IPR000994) Peptidase M24, methionine aminopeptidase (IPR001714) Peptidase M24A, methionine aminopeptidase, subfamily 2 (IPR002468) Winged helix-turn-helix transcription repressor DNA-binding (IPR011991) MEROPS - An information resource for peptidases and the proteins that inhibit them • M24.002
Linkouts
	BioGRID - A database of protein and genetic interactions • 60391 DroID - A comprehensive database of gene and protein interactions. • FBgn0025117 DRSC - Results from RNAi screens. • FBgn0025117 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025117 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4008-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0025117 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34294 InParanoid A subset of ortholog calls from InParanoid. • AAEL004738-PA Aedes aegypti (mosquito) AGAP008345-PA Anopheles gambiae (mosquito) XP_624161.1 Apis mellifera (honey bee) XP_001945885.1 Acyrthosiphon pisum (pea aphid) At3g59990.1 Arabidopsis thaliana (wall cress) 36909 Batrachochytrium dendrobatidis (chytrid fungus) 124163 Branchiostoma floridae (lancelet) BGIBMGA009963-PA Bombyx mori (silk worm) ENSBTAP00000026568 Bos taurus (bovine) CAL0002793 Candida albicans (a form of yeast) CN02395 Caenorhabditis brenneri (small nematode) CBP03339 Caenorhabditis briggsae (nematode) CE24146 Caenorhabditis elegans (worm) ENSCAFP00000009531 Canis familiaris (dog) CAGL0G03641g Candida glabrata (haploid yeast) Chro.20263 Cryptosporidium hominis (obligate parasite) ENSCINP00000011313 Ciona intestinalis (sea squirt) JA09885 Caenorhabditis japonica (nematode) CMP247C Cyanidioschyzon merolae (red alga) cn07191 Cryptococcus neoformans (yeast-like fungus) cgd2_2480 Cryptosporidium parvum (protozoan parasite) CPIJ020069 Culex pipens (mosquito) ENSCPOP00000013987 Cavia porcellus (guinea pig) 120712 Chlamidomonas reinhardtii (green alga) RP28278 Caenorhabditis remanei (nematode) ENSCSAVP00000012918 Ciona savignyi (sedentary tunicate) 173347 Capitella spl (polychaete worm) DDB0190923 Dictyostelium discoideum (amoeba) DEHA2C03894g Debaryomyces Hansenii (yeast) 57172 Daphnia pulex (daphnia) ENSDARP00000003646 Danio rerio (zebra fish) ENSECAP00000013236 Equus caballus (horse) XP_651539 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000006033 Gymnopilus aculeatus (mushroom) ENSGALP00000018537 Gallus gallus (chicken) GL50803_86600 Giardia lamblia (flagellated protozoan) 65192 Hypsipyla robusta (cedar shoot borer) ENSP00000325312 Homo sapiens (human) ISCW011848-PA Ixodes scapularis (deer tick) KLLA0E06887g Kluyveromyces lactis (yeast) 179055 Lottia gigantea (owl limpet) LmjF21.0840 Leishmania major (virus) 37121 Monocosta brevicollis (choanoflagellate) ENSMODP00000010154 Monodelphis domestica (gray opossum) ENSMMUP00000018164 Macaca mulatta (rhesus monkey) ENSMUSP00000048285 Mus musculus (house mouse) 181577 Nematostella vectensis (starlet anemone) XP_001600756.1 Nasonia vitripennis (wasp) ENSOANP00000005136 Ornithorynchus anatinus (platypus) ENSORLP00000020836 Oryzias latipes (japanese killifish) LOC_Os12g43370.1 Oryza sativa (asian rice) 27405 Ostreococcus tauri (green alga) PF14_0327 Plasmodium falciparum (protozoal parasite) PHUM000018-PA Pediculus humanus (human body louse) PP21335 Pristionchus pacificus (nematode) 203982 Physcomitrella patens (moss) ENSPPYP00000005526 Pongo pygmaeus (orangutan) 71370 Phytophthora ramorum (sudden oak death pathogen) 109386 Phytophthora sojae (root rot pathogen) 198596 Populus trichocarpa (black cottonwood) ENSPTRP00000009029 Pan troglodytes (chimpanzee) PVX_084805 Plasmodium vivax (protozoal parasite) ENSRNOP00000021149 Rattus norvegicus (norway rat) 4764684 Sorghum bicolor (sorghum) YBL091C Saccharomyces cerevisiae (budding yeast) Smp_011120 Schistosoma mansoni (trematode parasite) SPBC14C8.03 Schizosaccharomyces pombe (fission yeast) XP_780497.2 Strongylocentrotus purpuratus (purple sea urchin) 61709 Trichoplax adhaerens (metazoa) TA18485 Theileria annulata (apicomplexan parasite) XP_969150.1 Tribolium castaneum (red flour beetle) Tc00.1047053506457.10 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053509693.50 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000001034 Tetraodon nigroviridis (green spotted pufferfish) TP03_0593 Theileria parva (parasitic protozoan) 24414 Thalassiosira pseudonana (marine diatom) ENSTRUP00000038362 Takifugu rubripes (pufferfish Takifugu) 3814.m00912 Tetrahymena thermophila (ciliate protozoa) 91003.m00121 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000020290 Xenopus tropicalis (frog) YALI0D05159g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34294 modMine - Data generated by the modENCODE project. • FBgn0025117 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV17109 LH12846 ISCW011848 FBgn0236248 FBgn0226153 FBgn0200715 FBgn0195004 FBgn0172590 JGI_V11_57172 FBgn0077860 FBgn0156533 FBgn0142832 FBgn0132599 FBgn0102365 FBgn0099800 FBgn0098354 CPIJ011945 CPIJ020069 BGIBMGA009963 ACYPI004880 GB13458 AGAP008345 AAEL004738 PB23795 PHUM576050 GLEAN_06844
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG4008 (Keleman et al., 2009.8.5, Cammarato et al., 2011) DMAP2 (Cutforth and Gaul, 1999) MAP2 (Giglione et al., 2000) und (Christensen and Cook, 2006.12.5, Christensen and Cook, 2006.8.30, Wasbrough et al., 2010)
Name Synonym	uninitiated (Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 26 )
Generate a list of	All references relating to this gene ( 26 )
List References by type	Research paper  ( 4 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...