A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\unc-119

General Information
SymbolDmel\unc-119SpeciesD. melanogaster
Nameunc-119Annotation symbolCG1659
Feature typeprotein_coding_geneFlyBase IDFBgn0025549
Gene Model StatusCurrent Stock availability 3 publicly available
Genomic Location
Chromosome (arm)XRecombination map
Cytogenetic map7B1-7B1Sequence locationX:7,182,713..7,185,337 [-]

Genomic Maps

GBrowse View Help
modENCODE GBrowse
detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene unc-119 is referred to in FlyBase by the symbol Dmel\unc-119 (CG1659, FBgn0025549). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GMP phosphodiesterase, delta subunit; Immunoglobulin E-set. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval Malpighian tubules, larval fat body, larval salivary gland, adult ovary, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1628148_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of unc-119. Gene sequence location is X:7182713..7185337.

hide Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01
Sequence features
Controlled Vocabulary Terms
Unknown
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
7B1-7B1  
Limits computationally determined from genome sequence between P{EP}CG9650EP1340&P{EP}CG9650EP1617 and P{EP}CBPEP1643&P{EP}EP1523EP1523  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
7A1-7A1  
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\unc-119 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0303414 FBtr0071047 FBtr0071066 FBtr0303415 FBpp0292475 FBpp0071006 FBpp0071024 FBti0075873 FBti0041765
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0071066
  2037
  265
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0071024  
28.4  
265  
4.51  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
unc-119 transcript is first expressed at embryonic stage 11, in the neuromeres of the presumptive central nervous system. This pattern is maintained through the end of embryonic development. unc-119 transcript is also expressed in dorsal, lateral and ventral sensory clusters, in neurons of the anntenno-maxillary complex, and in the dorsal sensory cluster of the telson.
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view CG2059-RB CG2059-RA unc-119-RA CG1677-RB
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0025549


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0025549
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0025549 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 3162
embryo 02-04hr
 
 3678
embryo 04-06hr
 
 2517
embryo 06-08hr
 
 1851
embryo 08-10hr
 
 1786
embryo 10-12hr
 
 1430
embryo 12-14hr
 
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 
 1455
white prepupae 12hr
 
 1900
white prepupae 24hr
 
 2174
pupae 2d postWPP
 
 2004
pupae 3d postWPP
 
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 
 2015
adult female 30day
 
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3162)
embryo 02-04hr
 (3678)
embryo 04-06hr
 (2517)
embryo 06-08hr
 (1851)
embryo 08-10hr
 (1786)
embryo 10-12hr
 (1430)
embryo 12-14hr
 (1577)
embryo 14-16hr
 (762)
embryo 16-18hr
 (938)
embryo 18-20hr
 (617)
embryo 20-22hr
 (654)
embryo 22-24hr
 (915)
larva L1
 (464)
larva L2
 (340)
larva L3 12hr old
 (268)
larva L3 puffstage 1-2
 (444)
larva L3 puffstage 3-6
 (888)
larva L3 puffstage 7-9
 (1367)
white prepupae new
 (1455)
white prepupae 12hr
 (1900)
white prepupae 24hr
 (2174)
pupae 2d postWPP
 (2004)
pupae 3d postWPP
 (1525)
pupae 4d postWPP
 (590)
adult male 01day
 (817)
adult male 05day
 (938)
adult male 30day
 (667)
adult female 01day
 (872)
adult female 05day
 (2015)
adult female 30day
 (2012)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3162)
embryo 02-04hr
 (3678)
embryo 04-06hr
 (2517)
embryo 06-08hr
 (1851)
embryo 08-10hr
 (1786)
embryo 10-12hr
 1430
embryo 12-14hr
 (1577)
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 1455
white prepupae 12hr
 (1900)
white prepupae 24hr
 (2174)
pupae 2d postWPP
 (2004)
pupae 3d postWPP
 (1525)
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 (2015)
adult female 30day
 (2012)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3162
embryo 02-04hr
 
 3678
embryo 04-06hr
 
 2517
embryo 06-08hr
 
 1851
embryo 08-10hr
 
 1786
embryo 10-12hr
 
 1430
embryo 12-14hr
 
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 
 1455
white prepupae 12hr
 
 1900
white prepupae 24hr
 
 2174
pupae 2d postWPP
 
 2004
pupae 3d postWPP
 
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 
 2015
adult female 30day
 
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3162
embryo 02-04hr
 
 3678
embryo 04-06hr
 
 2517
embryo 06-08hr
 
 1851
embryo 08-10hr
 
 1786
embryo 10-12hr
 
 1430
embryo 12-14hr
 
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 
 1455
white prepupae 12hr
 
 1900
white prepupae 24hr
 
 2174
pupae 2d postWPP
 
 2004
pupae 3d postWPP
 
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 
 2015
adult female 30day
 
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0025549 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 3162
embryo 02-04hr
 
 3678
embryo 04-06hr
 
 2517
embryo 06-08hr
 
 1851
embryo 08-10hr
 
 1786
embryo 10-12hr
 
 1430
embryo 12-14hr
 
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 
 1455
white prepupae 12hr
 
 1900
white prepupae 24hr
 
 2174
pupae 2d postWPP
 
 2004
pupae 3d postWPP
 
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 
 2015
adult female 30day
 
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3162)
embryo 02-04hr
 (3678)
embryo 04-06hr
 (2517)
embryo 06-08hr
 (1851)
embryo 08-10hr
 (1786)
embryo 10-12hr
 (1430)
embryo 12-14hr
 (1577)
embryo 14-16hr
 (762)
embryo 16-18hr
 (938)
embryo 18-20hr
 (617)
embryo 20-22hr
 (654)
embryo 22-24hr
 (915)
larva L1
 (464)
larva L2
 (340)
larva L3 12hr old
 (268)
larva L3 puffstage 1-2
 (444)
larva L3 puffstage 3-6
 (888)
larva L3 puffstage 7-9
 (1367)
white prepupae new
 (1455)
white prepupae 12hr
 (1900)
white prepupae 24hr
 (2174)
pupae 2d postWPP
 (2004)
pupae 3d postWPP
 (1525)
pupae 4d postWPP
 (590)
adult male 01day
 (817)
adult male 05day
 (938)
adult male 30day
 (667)
adult female 01day
 (872)
adult female 05day
 (2015)
adult female 30day
 (2012)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (3162)
embryo 02-04hr
 (3678)
embryo 04-06hr
 (2517)
embryo 06-08hr
 1851
embryo 08-10hr
 1786
embryo 10-12hr
 1430
embryo 12-14hr
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 1455
white prepupae 12hr
 1900
white prepupae 24hr
 2174
pupae 2d postWPP
 2004
pupae 3d postWPP
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 2015
adult female 30day
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3162
embryo 02-04hr
 
 3678
embryo 04-06hr
 
 2517
embryo 06-08hr
 
 1851
embryo 08-10hr
 
 1786
embryo 10-12hr
 
 1430
embryo 12-14hr
 
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 
 1455
white prepupae 12hr
 
 1900
white prepupae 24hr
 
 2174
pupae 2d postWPP
 
 2004
pupae 3d postWPP
 
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 
 2015
adult female 30day
 
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 3162
embryo 02-04hr
 
 3678
embryo 04-06hr
 
 2517
embryo 06-08hr
 
 1851
embryo 08-10hr
 
 1786
embryo 10-12hr
 
 1430
embryo 12-14hr
 
 1577
embryo 14-16hr
 
 762
embryo 16-18hr
 
 938
embryo 18-20hr
 
 617
embryo 20-22hr
 
 654
embryo 22-24hr
 
 915
larva L1
 
 464
larva L2
 
 340
larva L3 12hr old
 
 268
larva L3 puffstage 1-2
 
 444
larva L3 puffstage 3-6
 
 888
larva L3 puffstage 7-9
 
 1367
white prepupae new
 
 1455
white prepupae 12hr
 
 1900
white prepupae 24hr
 
 2174
pupae 2d postWPP
 
 2004
pupae 3d postWPP
 
 1525
pupae 4d postWPP
 
 590
adult male 01day
 
 817
adult male 05day
 
 938
adult male 30day
 
 667
adult female 01day
 
 872
adult female 05day
 
 2015
adult female 30day
 
 2012
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0025549


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0025549
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval Malpighian tubules, larval fat body, larval salivary gland, adult ovary, adult male reproductive system.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0025549 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 
 579.4
Adult Thoracic-Abdominal Ganglion
 
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 (579.4)
Adult Thoracic-Abdominal Ganglion
 (630.1)
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 
 579.4
Adult Thoracic-Abdominal Ganglion
 
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 
 579.4
Adult Thoracic-Abdominal Ganglion
 
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0025549 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 
 579.4
Adult Thoracic-Abdominal Ganglion
 
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 579.4
Adult Thoracic-Abdominal Ganglion
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 
 579.4
Adult Thoracic-Abdominal Ganglion
 
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 390.975
Larval Midgut
 
 81
Larval Hindgut
 
 54.5
Larval Malpighian Tubules
 
 152.1
Larval Fat Body
 
 132.5
Larval Salivary Gland
 
 101.1
Larval Trachea
 
 83.875
Larval Carcass
 
 54.675
Adult Head
 
 171.6
Adult Eye
 
 132.425
Adult Brain
 
 579.4
Adult Thoracic-Abdominal Ganglion
 
 630.1
Adult Crop
 
 72
Adult Midgut
 
 86.9
Adult Hindgut
 
 60.9
Adult Malpighian Tubules
 
 64.2
Adult Fat Body
 
 74.2
Adult Salivary Gland
 
 79.4
Adult Heart
 
 73.425
Adult VirginFemale Spermatheca
 
 74.8
Adult InseminatedFemale Spermatheca
 
 84
Adult Ovary
 
 453.2
Adult Testis
 
 186.3
Adult Male Accessory Gland
 
 237.2
Adult Carcass
 
 75.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 171.6
 
NA 
Eye
 
 132.425
 
NA 
Brain
 
 579.4
 
390.975 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 630.1
 
NA 
Crop
 
 72
 
81 
Midgut
 
 86.9
 
54.5 
Hindgut
 
 60.9
 
152.1 
Malpighian Tubules
 
 64.2
 
132.5 
Fat Body
 
 74.2
 
101.1 
Salivary Gland
 
 79.4
 
NA 
Heart
 
 73.425
 
83.875 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 74.8
 
NA 
InseminatedFemale Spermatheca
 
 84
 
NA 
Ovary
 
 453.2
 
NA 
Testis
 
 186.3
 
NA 
Male Accessory Gland
 
 237.2
 
54.675 
Carcass
 
 75.7

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 1 )
For All Classical Alleles Show

Allele of unc-119ClassMutagenStocksKnown lesion
unc-119EY202211 --
hide Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show

Allele of unc-119ClassMutagenStocksKnown lesion
unc-119GD91801 Yes
unc-119KK1087181 Yes
hide Aneuploid Aberrations
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
UAS construct
Insertions
Type of insertions
Name
Expression data
insertion of mobile activating element
hide Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

There is no information supporting a cellular component term for this gene.

(Based on a review of available data before: 2006)

hide Terms Based on Experimental Evidence ( 0 terms )
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
unc-119 allele
Gene
References
hide External Data
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 3 )
Bloomington
VDRC
hide Genomic Clones ( 1 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 64 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
hide Antibody Information
hide Other Information
hide Discoverer
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
hide Other Comments
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym
anon-EST:Posey123
 
Name Synonym
unc-119
 
Secondary FlyBase IDs
hide References ( 19 )
Research paper
Blanco et al., 2010, BMC Dev. Biol. 10: 94
Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
McGraw et al., 2008, Genetics 179(3): 1395--1408
Post-mating gene expression profiles of female Drosophila melanogaster in response to time and to four male accessory gland proteins. [FBrf0207105]
Engström et al., 2007, Genome Res. 17(12): 1898--1908
Genomic regulatory blocks underlie extensive microsynteny conservation in insects. [FBrf0202619]
Glinka et al., 2006, Molec. Biol. Evol. 23(10): 1869--1878
Evidence of gene conversion associated with a selective sweep in Drosophila melanogaster. [FBrf0191833]
Ruvinsky and Ruvkun, 2003, Development 130(21): 5133--5142
Functional tests of enhancer conservation between distantly related species. [FBrf0162086]
Markstein et al., 2002, Proc. Natl. Acad. Sci. USA 99(2): 763--768
Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo. [FBrf0145207]
Maduro et al., 2000, J. Neurogenet. 13(4): 191--212
The UNC-119 family of neural proteins is functionally conserved between humans, Drosophila and C. elegans. [FBrf0129954]
Supplementary material
The modENCODE Consortium, 2010, Science 330(6012):
DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):
Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):
Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center
RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Bellen, 2006.8.3, MBBatch686_2.xml
MBBatch686_2.xml [FBrf0191805]
FlyBase analysis
FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase.
Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
DNA/RNA sequence record
Schoefl, 2005.3.8, GenBank/EMBL/DDBJ: AJ889432
Drosophila melanogaster X chromosome fragment, LV125KAM11. [FBrf0196788]
Maduro, 1999.1.10, GenBank/EMBL/DDBJ: AF119102
Drosophila melanogaster UNC-119 (unc-119) gene, complete cds. [FBrf0117636]
Computer file
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0125078]