The gene unc-119 is referred to in FlyBase by the symbol Dmel\unc-119 (CG1659, FBgn0025549). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GMP phosphodiesterase, delta subunit; Immunoglobulin E-set. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval Malpighian tubules, larval fat body, larval salivary gland, adult ovary, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1628148_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of unc-119. Gene sequence location is X:7182713..7185337.
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unc-119 transcript is first expressed at embryonic stage 11, in the neuromeres of the presumptive central nervous system. This pattern is maintained through the end of embryonic development. unc-119 transcript is also expressed in dorsal, lateral and ventral sensory clusters, in neurons of the anntenno-maxillary complex, and in the dorsal sensory cluster of the telson.
modENCODE Temporal Expression Data for FBgn0025549
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.
[download data (TSV)]
Guide to modENCODE expression level colors
No expression (0 - 0)
Extremely low expression (1 - 10)
Very low expression (11 - 100)
Low expression (101 - 400)
Moderate expression (401 - 1400)
Moderately high expression (1401 - 4000)
High expression (4001 - 10000)
Very high expression (10001 - 100000)
Extremely high expression (100001 - 2000000)
Linear, scaled to maximum FBgn0025549 expression level
Developmental Stage
Expression Level
embryo 00-02hr
3162
embryo 02-04hr
3678
embryo 04-06hr
2517
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Very low expression
Developmental Stage
Expression Level
embryo 00-02hr
(3162)
embryo 02-04hr
(3678)
embryo 04-06hr
(2517)
embryo 06-08hr
(1851)
embryo 08-10hr
(1786)
embryo 10-12hr
(1430)
embryo 12-14hr
(1577)
embryo 14-16hr
(762)
embryo 16-18hr
(938)
embryo 18-20hr
(617)
embryo 20-22hr
(654)
embryo 22-24hr
(915)
larva L1
(464)
larva L2
(340)
larva L3 12hr old
(268)
larva L3 puffstage 1-2
(444)
larva L3 puffstage 3-6
(888)
larva L3 puffstage 7-9
(1367)
white prepupae new
(1455)
white prepupae 12hr
(1900)
white prepupae 24hr
(2174)
pupae 2d postWPP
(2004)
pupae 3d postWPP
(1525)
pupae 4d postWPP
(590)
adult male 01day
(817)
adult male 05day
(938)
adult male 30day
(667)
adult female 01day
(872)
adult female 05day
(2015)
adult female 30day
(2012)
Expression Level Scale
None
Extremely low
Very low
Low
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(3162)
embryo 02-04hr
(3678)
embryo 04-06hr
(2517)
embryo 06-08hr
(1851)
embryo 08-10hr
(1786)
embryo 10-12hr
1430
embryo 12-14hr
(1577)
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
(1900)
white prepupae 24hr
(2174)
pupae 2d postWPP
(2004)
pupae 3d postWPP
(1525)
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
(2015)
adult female 30day
(2012)
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
3162
embryo 02-04hr
3678
embryo 04-06hr
2517
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
3162
embryo 02-04hr
3678
embryo 04-06hr
2517
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to maximum FBgn0025549 expression level
Developmental Stage
Expression Level
embryo 00-02hr
3162
embryo 02-04hr
3678
embryo 04-06hr
2517
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
log, scaled to Very low expression
Developmental Stage
Expression Level
embryo 00-02hr
(3162)
embryo 02-04hr
(3678)
embryo 04-06hr
(2517)
embryo 06-08hr
(1851)
embryo 08-10hr
(1786)
embryo 10-12hr
(1430)
embryo 12-14hr
(1577)
embryo 14-16hr
(762)
embryo 16-18hr
(938)
embryo 18-20hr
(617)
embryo 20-22hr
(654)
embryo 22-24hr
(915)
larva L1
(464)
larva L2
(340)
larva L3 12hr old
(268)
larva L3 puffstage 1-2
(444)
larva L3 puffstage 3-6
(888)
larva L3 puffstage 7-9
(1367)
white prepupae new
(1455)
white prepupae 12hr
(1900)
white prepupae 24hr
(2174)
pupae 2d postWPP
(2004)
pupae 3d postWPP
(1525)
pupae 4d postWPP
(590)
adult male 01day
(817)
adult male 05day
(938)
adult male 30day
(667)
adult female 01day
(872)
adult female 05day
(2015)
adult female 30day
(2012)
Expression Level Scale
None
Extremely low
Very low
Low
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(3162)
embryo 02-04hr
(3678)
embryo 04-06hr
(2517)
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
3162
embryo 02-04hr
3678
embryo 04-06hr
2517
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
3162
embryo 02-04hr
3678
embryo 04-06hr
2517
embryo 06-08hr
1851
embryo 08-10hr
1786
embryo 10-12hr
1430
embryo 12-14hr
1577
embryo 14-16hr
762
embryo 16-18hr
938
embryo 18-20hr
617
embryo 20-22hr
654
embryo 22-24hr
915
larva L1
464
larva L2
340
larva L3 12hr old
268
larva L3 puffstage 1-2
444
larva L3 puffstage 3-6
888
larva L3 puffstage 7-9
1367
white prepupae new
1455
white prepupae 12hr
1900
white prepupae 24hr
2174
pupae 2d postWPP
2004
pupae 3d postWPP
1525
pupae 4d postWPP
590
adult male 01day
817
adult male 05day
938
adult male 30day
667
adult female 01day
872
adult female 05day
2015
adult female 30day
2012
Expression Level Scale
None
Extremely low
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
FlyAtlas Anatomical Expression Data for FBgn0025549
Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, larval Malpighian tubules, larval fat body, larval salivary gland, adult ovary, adult male reproductive system.
[download data (TSV)]
Guide to FlyAtlas expression level colors
No expression (0 - 9.999)
Low expression (10 - 99.999)
Moderate expression (100 - 499.999)
High level expression (500 - 999.999)
Very high expression (1000 - 25000)
Linear, scaled to maximum FBgn0025549 expression level
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
(579.4)
Adult Thoracic-Abdominal Ganglion
(630.1)
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to maximum FBgn0025549 expression level
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
390.975
Larval Midgut
81
Larval Hindgut
54.5
Larval Malpighian Tubules
152.1
Larval Fat Body
132.5
Larval Salivary Gland
101.1
Larval Trachea
83.875
Larval Carcass
54.675
Adult Head
171.6
Adult Eye
132.425
Adult Brain
579.4
Adult Thoracic-Abdominal Ganglion
630.1
Adult Crop
72
Adult Midgut
86.9
Adult Hindgut
60.9
Adult Malpighian Tubules
64.2
Adult Fat Body
74.2
Adult Salivary Gland
79.4
Adult Heart
73.425
Adult VirginFemale Spermatheca
74.8
Adult InseminatedFemale Spermatheca
84
Adult Ovary
453.2
Adult Testis
186.3
Adult Male Accessory Gland
237.2
Adult Carcass
75.7
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 64 )
Please Note
This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see GBrowse for alignment of the cDNAs and ESTs
to the gene model.