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Gene Dmel\DAAM

General Information
Symbol	Dmel\DAAM	Species	D. melanogaster
Name	Dishevelled Associated Activator of Morphogenesis	Annotation symbol	CG14622
Feature type	protein_coding_gene	FlyBase ID	FBgn0025641
Gene Model Status	Current	Stock availability	8 publicly available
Also Known As	EG:114D9.2, dDAAM
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	1F2-1F3	Sequence location	X:1,183,746..1,216,427 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Dishevelled Associated Activator of Morphogenesis is referred to in FlyBase by the symbol Dmel\DAAM (CG14622, FBgn0025641). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: actin binding. There is experimental evidence that it is involved in the biological process: actin filament bundle assembly; regulation of axonogenesis; positive regulation of filopodium assembly; regulation of filopodium assembly; regulation of tube architecture, open tracheal system; open tracheal system development. 23 alleles are reported. The phenotypes of these alleles are annotated with: organ system; multicellular structure; anatomical structure; organ system subdivision; tracheal system; cell part; portion of tissue; cell projection; acellular anatomical structure; organelle. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Actin-binding FH2; Actin-binding FH2/DRF autoregulatory; Armadillo-type fold; Diaphanous FH3; Diaphanous GTPase-binding; Diaphanous autoregulatory; GTPase-binding/formin homology 3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult brain, larval/adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1629015_a_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of DAAM. Gene sequence location is X:1183746..1216427.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Transcripts DAAM-RF DAAM-RE Polypeptides DAAM-PE DAAM-PF
FB2012_01	Sequence features HFA18479 BKN22882
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 1F2-1F3   Limits computationally determined from genome sequence between P{EP}EP1542 and P{EP}futschEP1419
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\DAAM for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.42 Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) DAAM-RA FBtr0070241  NM_130544   4274   1114 DAAM-RB FBtr0070239  NM_166876   5397   1153 DAAM-RD FBtr0303264  NM_001201593   5277   1463 DAAM-RE FBtr0310282     5414   1153 DAAM-RF FBtr0310283     5157   1153
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein DAAM-PA   FBpp0070231   125.5   1114   6.97     NP_569900   AAF45600 DAAM-PB   FBpp0070229   129.9   1153   6.90     NP_726724   AAN09040 DAAM-PD   FBpp0292356   162.3   1463   6.81     NP_001188522   ADV37606 DAAM-PE   FBpp0301965   129.9   1153   6.90       DAAM-PF   FBpp0301966   129.9   1153   6.90
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Actin-binding FH2/DRF autoregulatory (IPR003104) Diaphanous FH3 (IPR010472) GTPase-binding/formin homology 3 (IPR014768) Actin-binding FH2 (IPR015425) Diaphanous autoregulatory (IPR014767) Diaphanous GTPase-binding (IPR010473) Armadillo-type fold (IPR016024)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA942048   AE014298 AAF45600   AE014298 AAN09040   AE014298 ADV37606   AF171816   AL031640 CAA21052   AY118439 AAM48468   BI484790   BI623629   BI631718   BT021242 AAX33390   CO263834   CO271851   CO277094   CO324646   CO329617   CZ479464   CZ482270   CZ482271   CZ488700   CZ489112   CZ489113   EC052018   EC066602   EC083144   EC083634   EC223809   EC232730   EC250671   EL881180   EL881181   GH945501   GH953259   GH959388   GH964618   GH976377
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q5BII2 Q7KW17 Q7YZA4 Q8IRY0 Q8MT16 Q9W5A4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0025641    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0025641 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0025641 expression level Developmental Stage   Expression Level embryo 00-02hr    4333 embryo 02-04hr    4028 embryo 04-06hr    1290 embryo 06-08hr    1555 embryo 08-10hr    1988 embryo 10-12hr    1657 embryo 12-14hr    1947 embryo 14-16hr    5383 embryo 16-18hr    2253 embryo 18-20hr    1311 embryo 20-22hr    1667 embryo 22-24hr    1366 larva L1    715 larva L2    1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP    2744 pupae 3d postWPP    1356 pupae 4d postWPP    1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day    1733 adult female 05day    2109 adult female 30day    2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4333) embryo 02-04hr  (4028) embryo 04-06hr  (1290) embryo 06-08hr  (1555) embryo 08-10hr  (1988) embryo 10-12hr  (1657) embryo 12-14hr  (1947) embryo 14-16hr  (5383) embryo 16-18hr  (2253) embryo 18-20hr  (1311) embryo 20-22hr  (1667) embryo 22-24hr  (1366) larva L1  (715) larva L2  (1739) larva L3 12hr old  (600) larva L3 puffstage 1-2  (357) larva L3 puffstage 3-6  (729) larva L3 puffstage 7-9  (961) white prepupae new  (857) white prepupae 12hr  (1180) white prepupae 24hr  (1095) pupae 2d postWPP  (2744) pupae 3d postWPP  (1356) pupae 4d postWPP  (1722) adult male 01day  (982) adult male 05day  (1029) adult male 30day  (1042) adult female 01day  (1733) adult female 05day  (2109) adult female 30day  (2422) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4333) embryo 02-04hr  (4028) embryo 04-06hr    1290 embryo 06-08hr  (1555) embryo 08-10hr  (1988) embryo 10-12hr  (1657) embryo 12-14hr  (1947) embryo 14-16hr  (5383) embryo 16-18hr  (2253) embryo 18-20hr    1311 embryo 20-22hr  (1667) embryo 22-24hr    1366 larva L1    715 larva L2  (1739) larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP  (2744) pupae 3d postWPP    1356 pupae 4d postWPP  (1722) adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day  (1733) adult female 05day  (2109) adult female 30day  (2422) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4333 embryo 02-04hr    4028 embryo 04-06hr    1290 embryo 06-08hr    1555 embryo 08-10hr    1988 embryo 10-12hr    1657 embryo 12-14hr    1947 embryo 14-16hr    5383 embryo 16-18hr    2253 embryo 18-20hr    1311 embryo 20-22hr    1667 embryo 22-24hr    1366 larva L1    715 larva L2    1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP    2744 pupae 3d postWPP    1356 pupae 4d postWPP    1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day    1733 adult female 05day    2109 adult female 30day    2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4333 embryo 02-04hr    4028 embryo 04-06hr    1290 embryo 06-08hr    1555 embryo 08-10hr    1988 embryo 10-12hr    1657 embryo 12-14hr    1947 embryo 14-16hr    5383 embryo 16-18hr    2253 embryo 18-20hr    1311 embryo 20-22hr    1667 embryo 22-24hr    1366 larva L1    715 larva L2    1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP    2744 pupae 3d postWPP    1356 pupae 4d postWPP    1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day    1733 adult female 05day    2109 adult female 30day    2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0025641 expression level Developmental Stage   Expression Level embryo 00-02hr    4333 embryo 02-04hr    4028 embryo 04-06hr    1290 embryo 06-08hr    1555 embryo 08-10hr    1988 embryo 10-12hr    1657 embryo 12-14hr    1947 embryo 14-16hr    5383 embryo 16-18hr    2253 embryo 18-20hr    1311 embryo 20-22hr    1667 embryo 22-24hr    1366 larva L1    715 larva L2    1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP    2744 pupae 3d postWPP    1356 pupae 4d postWPP    1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day    1733 adult female 05day    2109 adult female 30day    2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4333) embryo 02-04hr  (4028) embryo 04-06hr  (1290) embryo 06-08hr  (1555) embryo 08-10hr  (1988) embryo 10-12hr  (1657) embryo 12-14hr  (1947) embryo 14-16hr  (5383) embryo 16-18hr  (2253) embryo 18-20hr  (1311) embryo 20-22hr  (1667) embryo 22-24hr  (1366) larva L1  (715) larva L2  (1739) larva L3 12hr old  (600) larva L3 puffstage 1-2  (357) larva L3 puffstage 3-6  (729) larva L3 puffstage 7-9  (961) white prepupae new  (857) white prepupae 12hr  (1180) white prepupae 24hr  (1095) pupae 2d postWPP  (2744) pupae 3d postWPP  (1356) pupae 4d postWPP  (1722) adult male 01day  (982) adult male 05day  (1029) adult male 30day  (1042) adult female 01day  (1733) adult female 05day  (2109) adult female 30day  (2422) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4333) embryo 02-04hr  (4028) embryo 04-06hr    1290 embryo 06-08hr  1555 embryo 08-10hr  1988 embryo 10-12hr  1657 embryo 12-14hr  1947 embryo 14-16hr  (5383) embryo 16-18hr  2253 embryo 18-20hr    1311 embryo 20-22hr  1667 embryo 22-24hr    1366 larva L1    715 larva L2  1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP  (2744) pupae 3d postWPP    1356 pupae 4d postWPP  1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day  1733 adult female 05day  2109 adult female 30day  2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4333 embryo 02-04hr    4028 embryo 04-06hr    1290 embryo 06-08hr    1555 embryo 08-10hr    1988 embryo 10-12hr    1657 embryo 12-14hr    1947 embryo 14-16hr    5383 embryo 16-18hr    2253 embryo 18-20hr    1311 embryo 20-22hr    1667 embryo 22-24hr    1366 larva L1    715 larva L2    1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP    2744 pupae 3d postWPP    1356 pupae 4d postWPP    1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day    1733 adult female 05day    2109 adult female 30day    2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4333 embryo 02-04hr    4028 embryo 04-06hr    1290 embryo 06-08hr    1555 embryo 08-10hr    1988 embryo 10-12hr    1657 embryo 12-14hr    1947 embryo 14-16hr    5383 embryo 16-18hr    2253 embryo 18-20hr    1311 embryo 20-22hr    1667 embryo 22-24hr    1366 larva L1    715 larva L2    1739 larva L3 12hr old    600 larva L3 puffstage 1-2    357 larva L3 puffstage 3-6    729 larva L3 puffstage 7-9    961 white prepupae new    857 white prepupae 12hr    1180 white prepupae 24hr    1095 pupae 2d postWPP    2744 pupae 3d postWPP    1356 pupae 4d postWPP    1722 adult male 01day    982 adult male 05day    1029 adult male 30day    1042 adult female 01day    1733 adult female 05day    2109 adult female 30day    2422 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0025641    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0025641 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult brain, larval/adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0025641 expression level Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules    1266.6 Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye    1000.325 Adult Brain    796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules    957.2 Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules  (1266.6) Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye  (1000.325) Adult Brain  (796.5) Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules  (957.2) Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules  (1266.6) Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye  1000.325 Adult Brain    796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules    957.2 Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules    1266.6 Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye    1000.325 Adult Brain    796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules    957.2 Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0025641 expression level Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules    1266.6 Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye    1000.325 Adult Brain    796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules    957.2 Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules  (1266.6) Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye  (1000.325) Adult Brain  796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules  (957.2) Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules  1266.6 Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye  1000.325 Adult Brain    796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules    957.2 Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    477.925 Larval Midgut    35.2 Larval Hindgut    67.9 Larval Malpighian Tubules    1266.6 Larval Fat Body    20.4 Larval Salivary Gland no informative data Larval Trachea    43.5 Larval Carcass    49.825 Adult Head    404.3 Adult Eye    1000.325 Adult Brain    796.5 Adult Thoracic-Abdominal Ganglion    421.3 Adult Crop    14.8 Adult Midgut    9.1 Adult Hindgut    24 Adult Malpighian Tubules    957.2 Adult Fat Body    33.1 Adult Salivary Gland    6.4 Adult Heart    38.45 Adult VirginFemale Spermatheca    8 Adult InseminatedFemale Spermatheca    7 Adult Ovary    371.3 Adult Testis    48.8 Adult Male Accessory Gland no informative data Adult Carcass    42.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    404.3   NA  Eye    1000.325   NA  Brain    796.5   477.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    421.3   NA  Crop    14.8   35.2  Midgut    9.1   67.9  Hindgut    24   1266.6  Malpighian Tubules    957.2   20.4  Fat Body    33.1   no informative data  Salivary Gland    6.4   NA  Heart    38.45   43.5  Trachea    NA   NA  VirginFemale Spermatheca    8   NA  InseminatedFemale Spermatheca    7   NA  Ovary    371.3   NA  Testis    48.8   NA  Male Accessory Gland    no informative data   49.825  Carcass    42.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025641 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14622-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for DAAM Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal (with DAAMEx1) DAAMEx36 DAAMEx68 lethal (with DAAMEx36) DAAMEx1 DAAMEx65 DAAMEx68 DAAMEx184 DAAMEx202 DAAMEx249 lethal (with DAAMEx65) DAAMEx36 DAAMEx68 DAAMEx184 DAAMEx202 DAAMEx249 lethal (with DAAMEx68) DAAMEx1 DAAMEx36 DAAMEx65 DAAMEx184 DAAMEx202 DAAMEx249 lethal (with DAAMEx184) DAAMEx36 DAAMEx65 DAAMEx68 DAAMEx202 DAAMEx249 lethal (with DAAMEx202) DAAMEx36 DAAMEx65 DAAMEx68 DAAMEx184 DAAMEx249 lethal (with DAAMEx249) DAAMEx36 DAAMEx65 DAAMEx68 DAAMEx184 DAAMEx202 lethal | embryonic stage, with Scer\GAL4elav-C155 DAAMC.Scer\UAS.P\T lethal | larval stage, with Scer\GAL4btl.PS DAAMFH1-FH2.Scer\UAS.T:Avic\GFP-YFP.Venus lethal | recessive DAAMEx36 DAAMEx65 DAAMEx68 DAAMEx184 DAAMEx202 DAAMEx249 semi-lethal DAAMEx1 viable, with Scer\GAL4btl.PS DAAMFH2.Scer\UAS.T:Hsap\MYC viable, with Scer\GAL4pnr-MD237 DAAMGD8382 viable (with DAAMEx1) DAAMEx65 DAAMEx184 DAAMEx202 DAAMEx249 viable (with DAAMEx65) DAAMEx1 viable (with DAAMEx184) DAAMEx1 viable (with DAAMEx202) DAAMEx1 viable (with DAAMEx249) DAAMEx1 Sterility Allele fertile DAAMEx1 Other Phenotypes Allele neuroanatomy defective DAAMEx68 neuroanatomy defective, with Scer\GAL4elav-C155 DAAMC.Scer\UAS.P\T DAAMDADm.Scer\UAS neuroanatomy defective, with Scer\GAL4sca-109-68 DAAMDADm.Scer\UAS.T:Avic\GFP-EGFP neuroanatomy defective (with DAAMEx1) DAAMEx68 neuroanatomy defective (with DAAMEx68) DAAMEx1 Phenotype manifest in Allele axon, with Scer\GAL4elav-C155 DAAMDADm.Scer\UAS commissure | embryonic stage, with Scer\GAL4elav-C155 DAAMC.Scer\UAS.P\T connective DAAMEx68 connective (with DAAMEx1) DAAMEx68 connective (with DAAMEx68) DAAMEx1 embryo DAAMEx68 embryo (with DAAMEx1) DAAMEx68 embryo (with DAAMEx68) DAAMEx1 embryonic/larval cuticle DAAMEx68 embryonic/larval trachea DAAMEx1 embryonic/larval tracheal system DAAMEx68 embryonic/larval tracheal system, with Scer\GAL4btl.PS DAAMFH1-FH2.Scer\UAS.T:Avic\GFP-YFP.Venus embryonic/larval tracheal system (with Df(1)AD11) DAAMEx68 fascicle DAAMEx68 fascicle (with DAAMEx1) DAAMEx68 fascicle (with DAAMEx68) DAAMEx1 fascicle | embryonic stage, with Scer\GAL4elav-C155 DAAMC.Scer\UAS.P\T filamentous actin DAAMEx68 filamentous actin & tracheal fusion cell, with DAAMC.Scer\UAS.P\T, Scer\GAL4btl.PS DAAMScer\UAS.P\T.cMa filamentous actin & tracheal fusion cell, with DAAMScer\UAS.P\T.cMa, Scer\GAL4btl.PS DAAMC.Scer\UAS.P\T filamentous actin & tracheal fusion cell, with Scer\GAL4btl.PS DAAMC.Scer\UAS.P\T filamentous actin & tracheolar cell, with Scer\GAL4btl.PS DAAMC.Scer\UAS.P\T filopodium (with DAAMEx1) DAAMEx68 filopodium (with DAAMEx68) DAAMEx1 lateral longitudinal fascicle DAAMEx68 lateral longitudinal fascicle (with DAAMEx1) DAAMEx68 lateral longitudinal fascicle (with DAAMEx68) DAAMEx1 neurite, with Scer\GAL4elav-C155 DAAMDADm.Scer\UAS neuropil DAAMEx68 neuropil (with DAAMEx1) DAAMEx68 neuropil (with DAAMEx68) DAAMEx1 neuropil | embryonic stage, with Scer\GAL4elav-C155 DAAMC.Scer\UAS.P\T taenidial fold DAAMEx68 taenidial fold, with Scer\GAL4btl.PS DAAMFH1-FH2.Scer\UAS.T:Avic\GFP-YFP.Venus ventral nerve cord, with Scer\GAL4elav-C155 DAAMDADm.Scer\UAS
Classical Alleles ( 14 )
For All Classical Alleles Show
Allele of DAAM Class Mutagen Stocks Known lesion DAAMe01658 piggyBac transposase 1 -- DAAMe04522 piggyBac transposase 1 -- DAAMf06061 piggyBac transposase 1 -- DAAMf06407 piggyBac transposase 1 -- DAAMG1567 P-element activity 1 -- DAAMMB03627 1 -- DAAMEx184 P-element activity 0 Yes DAAMEx1 P-element activity 0 Yes DAAMEx202 P-element activity 0 Yes DAAMEx249 P-element activity 0 Yes DAAMEx36 P-element activity 0 Yes DAAMEx65 P-element activity 0 Yes DAAMEx68 loss of function allele P-element activity 0 Yes DAAMGG01323 0 --
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of DAAM Class Mutagen Stocks Known lesion DAAMGD8382 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes DAAMKK102786 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes DAAMC.Scer\UAS.P\T in vitro construct - regulatory fusion 0 Yes DAAMCA.Scer\UAS 0 -- DAAMDADm.Scer\UAS.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - site directed mutagenesis in vitro construct - coding region fusion 0 Yes DAAMDADm.Scer\UAS in vitro construct - regulatory fusion in vitro construct - site directed mutagenesis 0 Yes DAAMFH1-FH2.Scer\UAS.T:Avic\GFP-YFP.Venus in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes DAAMFH2.Scer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes DAAMScer\UAS.P\T.cMa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)AC7 (Matusek et al., 2006) Df(1)AD11 (Matusek et al., 2006) Df(1)sta (Matusek et al., 2006)
Duplicated in	Dp(1;3)sta (Matusek et al., 2006) Dp(1;Y)Sz280 (Matusek et al., 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8382} NA P{KK102786} NA P{UAS-DAAM.C} NA P{UAS-Daam.CA} NA P{UAS-DAAM.DADm} NA P{UAS-DAAM.DADm-eGFP} NA P{UAS-DAAM.FH1-FH2} NA P{UAS-DAAM.FH2} NA P{UAS-DAAM.FL.M} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}DAAMG1567 NA P{EP}EP1542 NA P{Mae-UAS.6.11}DAAMGG01323 NA miscellaneous insertions PBac{RB}DAAMe01658 NA PBac{RB}DAAMe04522 NA PBac{WH}DAAMf06061 NA PBac{WH}DAAMf06407 NA insertion of enhancer trap P{lacW}l(1)G0302G0302 No insertion of enhancer trap binary system Mi{ET1}DAAMMB03627 No
Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )
Terms Based on Experimental Evidence ( 7 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
actin filament bundle assembly inferred from mutant phenotype (Matusek et al., 2006) open tracheal system development inferred from mutant phenotype (Matusek et al., 2006) positive regulation of filopodium assembly inferred from mutant phenotype (Gonçalves-Pimentel et al., 2011) regulation of axonogenesis inferred from direct assay (Matusek et al., 2008) regulation of filopodium assembly inferred from direct assay (Matusek et al., 2008) regulation of tube architecture, open tracheal system inferred from mutant phenotype (Matusek et al., 2006)
Cellular Component
CV term Evidence References
axonal growth cone inferred from direct assay (Matusek et al., 2008)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
actin binding inferred from electronic annotation with InterPro:IPR003104, InterPro:IPR010472, InterPro:IPR010473 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000) Rho GTPase binding inferred from electronic annotation with InterPro:IPR010473 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
actin cytoskeleton organization non-traceable author statement (Matusek et al., 2005) cuticle pattern formation non-traceable author statement (Matusek et al., 2005)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions DAAM allele Gene References unspecified Btk29A (Matusek et al., 2006) Rho1 (Matusek et al., 2006) Src42A (Matusek et al., 2006)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57637 DroID - A comprehensive database of gene and protein interactions. • FBgn0025641 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31075
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22176 Dere\GG12709 Dgri\GH17880 Dmoj\GI16449 Dper\GL14390 Dpse\GA13122 Dvir\GJ15849 Dwil\GK19910
Curated drosophilid orthologs	Dpse\GA13122
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013920-PA Aedes aegypti (mosquito) XP_392531.3 Apis mellifera (honey bee) XP_001947056.1 Acyrthosiphon pisum (pea aphid) At1g59910.1 Arabidopsis thaliana (wall cress) 89642 Batrachochytrium dendrobatidis (chytrid fungus) 122351 Branchiostoma floridae (lancelet) BGIBMGA008436-PA Bombyx mori (silk worm) ENSBTAP00000007855 Bos taurus (bovine) CN16910 Caenorhabditis brenneri (small nematode) CBP36136 Caenorhabditis briggsae (nematode) CE32443 Caenorhabditis elegans (worm) ENSCAFP00000022852 Canis familiaris (dog) ENSCINP00000025361 Ciona intestinalis (sea squirt) JA04873 Caenorhabditis japonica (nematode) cgd6_4150 Cryptosporidium parvum (protozoan parasite) CPIJ002006 Culex pipens (mosquito) ENSCPOP00000012226 Cavia porcellus (guinea pig) RP45973 Caenorhabditis remanei (nematode) ENSCSAVP00000007150 Ciona savignyi (sedentary tunicate) 175180 Capitella spl (polychaete worm) 306800 Daphnia pulex (daphnia) ENSDARP00000023227 Danio rerio (zebra fish) ENSECAP00000007739 Equus caballus (horse) ENSGACP00000013615 Gymnopilus aculeatus (mushroom) ENSGALP00000037454 Gallus gallus (chicken) 89568 Hypsipyla robusta (cedar shoot borer) ENSP00000247170 Homo sapiens (human) ISCW018883-PA Ixodes scapularis (deer tick) 159871 Lottia gigantea (owl limpet) 8965 Monocosta brevicollis (choanoflagellate) ENSMODP00000031300 Monodelphis domestica (gray opossum) ENSMMUP00000027734 Macaca mulatta (rhesus monkey) ENSMUSP00000093299 Mus musculus (house mouse) 247373 Nematostella vectensis (starlet anemone) XP_001599441.1 Nasonia vitripennis (wasp) ENSOANP00000018770 Ornithorynchus anatinus (platypus) ENSORLP00000022252 Oryzias latipes (japanese killifish) PHUM002145-PA Pediculus humanus (human body louse) ENSPPYP00000006660 Pongo pygmaeus (orangutan) 134325 Phytophthora sojae (root rot pathogen) ENSPTRP00000043476 Pan troglodytes (chimpanzee) ENSRNOP00000005927 Rattus norvegicus (norway rat) XP_788329.2 Strongylocentrotus purpuratus (purple sea urchin) TA03495 Theileria annulata (apicomplexan parasite) XP_970309.2 Tribolium castaneum (red flour beetle) Tc00.1047053511393.30 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000019462 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000029278 Takifugu rubripes (pufferfish Takifugu) 3810.m01837 Tetrahymena thermophila (ciliate protozoa) 81246.m00092 Trichomonas vaginalis (parasitic flagellated protozoan) 96044.m00406 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000037098 Xenopus tropicalis (frog) YALI0D10879g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15970 LH20179 ISCW018883 FBgn0234050 FBgn0221907 FBgn0203036 FBgn0173890 JGI_V11_306800 FBgn0073160 FBgn0151995 FBgn0139197 FBgn0125349 FBgn0104996 FBgn0099175 CPIJ002005 CPIJ002006 BGIBMGA008436 ACYPI002207 GB12570 AGAP003292 AAEL013920 PB23668 PHUM230120 GLEAN_07082
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	24187 w1118 Mi{ET1}DAAMMB03627 33546 P{EP}CG18091G1567 DAAMG1567 w*
Harvard	- PBac{RB}DAAMe01658 - PBac{RB}DAAMe04522 - PBac{WH}DAAMf06061 - PBac{WH}DAAMf06407
VDRC	v103921 P{KK102786}VIE-260B v24885 w1118; P{GD8382}v24885
Genomic Clones ( 1 )
	BACR30G24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 23 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE67944 RH61354
Other clones	AF171816
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD26058 RH55943
Other clones	1694 15005 15171 66443 163093 190713 EC052018 EK104942 EK122934 EK136603 EK194436 EK293246 IP10982 RP004132483 RP004230317 RP004321140 RP004501630 RP004559921
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0025641 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31075
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: DAAM CG14622 (Matusek, 2005.9.6)
Source for database merge of
Additional comments	"l(1)G0302" may affect "CG14622". (Peter et al., 2002)
Other Comments
	Rho1 is an upstream regulator of DAAM, while Src42A and Btk29A act downstream or in parallel of DAAM. (Matusek et al., 2006) Appears to be function downstream of Rho1 and upstream of Src42A and Btk29A. (Matusek et al., 2005) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130544 NM_166876 NM_001201593 RefSeq (Proteins) • NP_569900 NP_726724 NP_001188522 DDBJ / EMBL / GenBank • AA942048 AAF45600 AAF45601 AAM48468 AAN09040 AAX33390 ADV37606 AF171816 AL031640 AY118439 BI484790 BI631718 BT021242 CAA21052 CZ479464 CZ482270 CZ482271 CZ488700 CZ489112 CZ489113 Entrez Gene - A searchable database of RefSeq genes. • 31075 UniProtKB/TrEMBL • Q5BII2 Q7KW17 Q7YZA4 Q8IRY0 Q8MT16 Q9W5A4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Actin-binding FH2/DRF autoregulatory (IPR003104) Diaphanous FH3 (IPR010472) GTPase-binding/formin homology 3 (IPR014768) Actin-binding FH2 (IPR015425) Diaphanous autoregulatory (IPR014767) Diaphanous GTPase-binding (IPR010473) Armadillo-type fold (IPR016024)
Linkouts
	BioGRID - A database of protein and genetic interactions • 57637 DroID - A comprehensive database of gene and protein interactions. • FBgn0025641 DRSC - Results from RNAi screens. • FBgn0025641 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025641 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14622-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0025641 FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways • 351102 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31075 InParanoid A subset of ortholog calls from InParanoid. • AAEL013920-PA Aedes aegypti (mosquito) XP_392531.3 Apis mellifera (honey bee) XP_001947056.1 Acyrthosiphon pisum (pea aphid) At1g59910.1 Arabidopsis thaliana (wall cress) 89642 Batrachochytrium dendrobatidis (chytrid fungus) 122351 Branchiostoma floridae (lancelet) BGIBMGA008436-PA Bombyx mori (silk worm) ENSBTAP00000007855 Bos taurus (bovine) CN16910 Caenorhabditis brenneri (small nematode) CBP36136 Caenorhabditis briggsae (nematode) CE32443 Caenorhabditis elegans (worm) ENSCAFP00000022852 Canis familiaris (dog) ENSCINP00000025361 Ciona intestinalis (sea squirt) JA04873 Caenorhabditis japonica (nematode) cgd6_4150 Cryptosporidium parvum (protozoan parasite) CPIJ002006 Culex pipens (mosquito) ENSCPOP00000012226 Cavia porcellus (guinea pig) RP45973 Caenorhabditis remanei (nematode) ENSCSAVP00000007150 Ciona savignyi (sedentary tunicate) 175180 Capitella spl (polychaete worm) 306800 Daphnia pulex (daphnia) ENSDARP00000023227 Danio rerio (zebra fish) ENSECAP00000007739 Equus caballus (horse) ENSGACP00000013615 Gymnopilus aculeatus (mushroom) ENSGALP00000037454 Gallus gallus (chicken) 89568 Hypsipyla robusta (cedar shoot borer) ENSP00000247170 Homo sapiens (human) ISCW018883-PA Ixodes scapularis (deer tick) 159871 Lottia gigantea (owl limpet) 8965 Monocosta brevicollis (choanoflagellate) ENSMODP00000031300 Monodelphis domestica (gray opossum) ENSMMUP00000027734 Macaca mulatta (rhesus monkey) ENSMUSP00000093299 Mus musculus (house mouse) 247373 Nematostella vectensis (starlet anemone) XP_001599441.1 Nasonia vitripennis (wasp) ENSOANP00000018770 Ornithorynchus anatinus (platypus) ENSORLP00000022252 Oryzias latipes (japanese killifish) PHUM002145-PA Pediculus humanus (human body louse) ENSPPYP00000006660 Pongo pygmaeus (orangutan) 134325 Phytophthora sojae (root rot pathogen) ENSPTRP00000043476 Pan troglodytes (chimpanzee) ENSRNOP00000005927 Rattus norvegicus (norway rat) XP_788329.2 Strongylocentrotus purpuratus (purple sea urchin) TA03495 Theileria annulata (apicomplexan parasite) XP_970309.2 Tribolium castaneum (red flour beetle) Tc00.1047053511393.30 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000019462 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000029278 Takifugu rubripes (pufferfish Takifugu) 3810.m01837 Tetrahymena thermophila (ciliate protozoa) 81246.m00092 Trichomonas vaginalis (parasitic flagellated protozoan) 96044.m00406 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000037098 Xenopus tropicalis (frog) YALI0D10879g Yarrowia lipolytica (nonconventional yeast) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /cytoskel/damm1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31075 modMine - Data generated by the modENCODE project. • FBgn0025641 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15970 LH20179 ISCW018883 FBgn0234050 FBgn0221907 FBgn0203036 FBgn0173890 JGI_V11_306800 FBgn0073160 FBgn0151995 FBgn0139197 FBgn0125349 FBgn0104996 FBgn0099175 CPIJ002005 CPIJ002006 BGIBMGA008436 ACYPI002207 GB12570 AGAP003292 AAEL013920 PB23668 PHUM230120 GLEAN_07082
Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	anon-EST:Posey148   CG14622 (Goldstein and Gunawardena, 2000, Tanaka et al., 2004, Benos, 2000.12.13, Matusek et al., 2006, Rogers et al., 2003, Negre et al., 2006, Georlette et al., 2007, Keleman et al., 2009.8.5, Zeitlinger et al., 2007, Aerts et al., 2010) DAAM (Matusek et al., 2006, Matusek et al., 2008, Barkó et al., 2010, Aerts et al., 2010, Wasbrough et al., 2010, Gonçalves-Pimentel et al., 2011) daam (Leptin, 2005, Sánchez-Soriano et al., 2010) Daam (Warner and Longmore, 2009) dDAAM (Matusek et al., 2005, Matusek et al., 2008) EG:114D9.2 (Peter et al., 2002, Benos et al., 2001, Giot et al., 2003, Stuart et al., 2007) unnamed (Goldstein and Gunawardena, 2000)
Name Synonym	DIA-like (Rogers et al., 2003) Dishevelled Associated Activator of Morphogenesis (Matusek, 2005.9.6, Matusek et al., 2005) Dishevelled associated activator of morphogenesis (Matusek et al., 2006) Formin (Rogers et al., 2003, Pimentel et al., 2007, Cao et al., 2010)
Secondary FlyBase IDs
	FBgn0027752
References ( 41 )
Generate a list of	All references relating to this gene ( 41 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 11 ) Review  ( 1 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 2 ) FlyBase analysis  ( 2 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 5 )
	Gonçalves-Pimentel et al., 2011, PLoS ONE 6(3): e18340 Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model. [FBrf0213367] Aerts et al., 2010, PLoS Biol. 8(7): e1000435 Robust Target Gene Discovery through Transcriptome Perturbations and Genome-Wide Enhancer Predictions in Drosophila Uncovers a Regulatory Basis for Sensory Specification. [FBrf0211419] Barkó et al., 2010, J. Biol. Chem. 285(17): 13154--13169 Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM. [FBrf0210590] Cao et al., 2010, Curr. Biol. 20(8): 770--776 Cortical Actin Dynamics Facilitate Early-Stage Centrosome Separation. [FBrf0211162] Sánchez-Soriano et al., 2010, Dev. Neurobiol. 70(1): 58--71 Drosophila growth cones: a genetically tractable platform for the analysis of axonal growth dynamics. [FBrf0209638] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...