FlyBase Gene Report: Dmel\Srpk79D

General Information

Symbol

Dmel\Srpk79D

Species

D. melanogaster

Name

Serine-arginine protein kinase at 79D

Annotation Symbol

CG11489

Feature Type

protein_coding_gene

FlyBase ID

FBgn0025702

Gene Model Status

Current

Stock Availability

11 publicly available

Gene Summary

Serine-arginine protein kinase at 79D (Srpk79D) is required to prevent the formation of axonal protein aggregates containing the active zone-protein encoded by brp. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

BEST:CK01209

Key Links

Genomic Location

Cytogenetic map

79D4-79D4

Sequence location

3L:22,273,985..22,284,335 [+]

Recombination map

3-47

RefSeq locus

NT_037436 REGION:22273985..22284335

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (13 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables protein kinase activity

inferred from direct assay

(Nieratschker et al., 2009)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables ATP binding

inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441

(InterPro Project Members, 2004-)

enables protein kinase activity

inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271

(InterPro Project Members, 2004-)

enables protein serine/threonine kinase activity

inferred from biological aspect of ancestor with PANTHER:PTN000622883

(GO Reference Genome Project, 2011-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in chemical synaptic transmission

inferred from mutant phenotype

(Johnson et al., 2009)

involved_in cytoskeletal matrix organization at active zone

inferred from mutant phenotype

(Johnson et al., 2009)

involved_in defense response to bacterium

inferred from mutant phenotype

(Ayres et al., 2008)

involved_in presynaptic active zone organization

inferred from genetic interaction with FLYBASE:Lrp4; FB:FBgn0030706

(Mosca et al., 2017)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in regulation of mRNA processing

inferred from biological aspect of ancestor with PANTHER:PTN000622883

(GO Reference Genome Project, 2011-)

involved_in spliceosomal complex assembly

inferred from biological aspect of ancestor with PANTHER:PTN000622883

(GO Reference Genome Project, 2011-)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in axon terminus

inferred from direct assay

(Mosca et al., 2017)

located_in presynaptic active zone

inferred from direct assay

(Johnson et al., 2009, Nieratschker et al., 2009)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000622884

(GO Reference Genome Project, 2011-)

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000622884

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

SERINE-ARGININE PROTEIN KINASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Serine-arginine protein kinase at 79D (Srpk79D) is required to prevent the formation of axonal protein aggregates containing the active zone-protein encoded by brp. [Date last reviewed: 2019-03-14]

Gene Group (FlyBase)

SERINE-ARGININE PROTEIN KINASES -: Serine-arginine protein kinases (SRPKs) are a group of serine kinases that phosphorylate proteins with serine-arginine dipeptide repeats, particularly targeting the SR family of splicing factors. SRPKs are constitutively active. They contain a well-conserved kinase domain that is bifurcated by a large non-conserved insert domain. (Adapted from PMID:21205204).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Srpk79D for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry M9NGC6)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Srpk79D-RB

FBtr0078496

NM_141130

3760

749

Srpk79D-RE

FBtr0303599

NM_001202231

3919

802

Srpk79D-RF

FBtr0303600

NM_001202232

4365

869

Srpk79D-RH

FBtr0304724

NM_001104190

4206

816

Srpk79D-RI

FBtr0306594

NM_001259950

3359

898

Srpk79D-RJ

FBtr0306595

NM_001259951

4706

965

Srpk79D-RK

FBtr0306596

NM_001259952

3900

1018

Srpk79D-RL

FBtr0306597

NM_001259953

3518

951

Srpk79D-RM

FBtr0334748

NM_001275279

4765

950

Srpk79D-RN

FBtr0334749

NM_001275280

3930

802

Srpk79D-RO

FBtr0334750

NM_001275281

3771

749

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Srpk79D-PB

FBpp0078148

84.6

749

6.04

FBpp0292632

90.2

802

5.00

FBpp0292633

94.0

869

5.85

FBpp0293266

88.5

816

6.77

FBpp0297549

99.5

898

6.19

FBpp0297550

103.4

965

6.83

FBpp0297551

108.9

1018

6.01

FBpp0297552

105.1

951

5.15

FBpp0306789

104.9

950

5.15

FBpp0306790

90.2

802

5.00

FBpp0306791

84.6

749

6.04

Q8T3S1

NP_001262210

AGB94903

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

749 aa isoforms: Srpk79D-PB, Srpk79D-PO

802 aa isoforms: Srpk79D-PE, Srpk79D-PN

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Srpk79D using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

2.77

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

larval central nervous system

(Johnson et al., 2009)

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

Additional Descriptive Data

Srpk79D is widely expressed but is enriched in the embryonic nervous system.

(Johnson et al., 2009)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in axon terminus

inferred from direct assay

(Mosca et al., 2017)

located_in presynaptic active zone

inferred from direct assay

(Johnson et al., 2009, Nieratschker et al., 2009)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Srpk79D in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Srpk79D

View exonic expression by tissue for Dmel\Srpk79D

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0025702

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40461/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0025702

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0025702

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0025702

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11489

Flygut - An atlas of the Drosophila adult midgut

FBgn0025702

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 10 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 16 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Srpk79D

Transgenic constructs containing regulatory region of Srpk79D

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3L)Exel6138

(Johnson et al., 2009, Ryder, 2004.4.26)

Inferred from location ( 4 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

Srpk79D^c00270

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Srpk79D^GD2777

viable, with Scer\GAL4^Mef2.PR

Srpk79D^GD2777

viable, with Scer\GAL4^pnr-MD237

Srpk79D^GD2777

viable, with Scer\GAL4^tin.CΔ4

Srpk79D^GD2777

Sterility

Allele

fertile

Srpk79D^c00270

Other Phenotypes

Allele

abnormal flight | recessive

abnormal locomotor behavior | recessive

abnormal neuroanatomy | adult stage, with Scer\GAL4^peb-GAL4

Srpk79D^GD2777

abnormal neuroanatomy | recessive

Srpk79D^VN100

abnormal neurophysiology, with Scer\GAL4^elav-C155

Srpk79D^UAS.Venus

abnormal smell perception | adult stage, with Scer\GAL4^peb-GAL4

Srpk79D^GD2777

decreased rate of feeding behavior | adult stage, with Scer\GAL4^yolk

Srpk79D^HMC04154

short lived | recessive

Phenotype manifest in

Allele

adult olfactory receptor neuron, with Scer\GAL4^peb-GAL4

Srpk79D^GD2777

axon

Srpk79D^P10036

neuron | larval stage

Srpk79D^VN100

presynaptic active zone | adult stage, with Scer\GAL4^peb-GAL4

Srpk79D^GD2777

synapse | adult stage, with Scer\GAL4^peb-GAL4

Srpk79D^GD2777

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (15)

Hsap\SRPK2

5 of 14

Yes

Hsap\SRPK3

5 of 14

Yes

4 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (13)

Rnor\Srpk2

6 of 14

Yes

5 of 14

4 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (13)

Mmus\Srpk3

5 of 14

Yes

4 of 14

4 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (12)

Xtro\srpk2

4 of 13

Yes

3 of 13

3 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (19)

Drer\srpk1a

4 of 14

Yes

Drer\srpk1b

4 of 14

Yes

Drer\srpk3

4 of 14

Yes

Drer\si:ch211-220i18.4

3 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\stk17al

1 of 14

Drer\stk17b

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (7)

Cele\spk-1

5 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (7)

Agam\AgaP_AGAP005322

2 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (24)

Atha\AT2G17530

8 of 13

Yes

Atha\AT3G44850

8 of 13

Yes

Atha\AT4G35500

8 of 13

Yes

Atha\AT5G22840

8 of 13

Yes

7 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (5)

Scer\SKY1

7 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (6)

Spom\dsk1

6 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Srpk79D. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (13)

SRPK

7 of 13

CG8565

6 of 13

bsk

1 of 13

CG42366

1 of 13

Doa

1 of 13

Dyrk2

1 of 13

Erk7

1 of 13

nmo

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SRPK2; SRSF protein kinase 2

5 of 14

602980

SRPK3; SRSF protein kinase 3

5 of 14

301002

INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 114; XLID114

SRPK1; SRSF protein kinase 1

4 of 14

601939

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Srpk79D

enzymatic study, autoradiography

(Driller et al., 2019)

Srpk79D - Lrp4

proximity ligation assay, fluorescence microscopy

(Mosca et al., 2017)

Srpk79D - brp

molecular sieving, molecular weight estimation by staining, two hybrid, peptide array, identification by antibody, enzymatic study, autoradiography

(Driller et al., 2019)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

fzr

suppressible

Srpk79D

(Neuert et al., 2017)

Lrp4

suppressible

Srpk79D

(Mosca et al., 2017)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

65697

DroID - A comprehensive database of gene and protein interactions.

FBgn0025702

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q8SWX7

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-47

Cytogenetic map

79D4-79D4

Sequence location

3L:22,273,985..22,284,335 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

79D4-79D4

Limits computationally determined from genome sequence between P{lacW}l(3)j1B10^j1B10 and P{lacW}l(3)j2C4^j2C4

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-47

(FlyBase, 2016)

3-44.0

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (11)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

10036

w¹¹¹⁸; PBac{PB}Srpk79D^c00270

56290

y¹ w^*; Mi{MIC}Srpk79D^MI11128

58648

y¹ w^*; Mi{MIC}Srpk79D^MI12767

22844

y¹ w^67c23; Mi{ET1}Srpk79D^MB00578

66813

y¹ w^*; Mi{Trojan-GAL4.0}Srpk79D^{MI11128-TG4.0}

605038

y¹ sc^* v¹ sev²¹; P{TKO.GS06105}attP2

55881

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04154}attP2

55667

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03822}attP40

VDRC

v102632

P{KK103400}VIE-260B

v47544

w¹¹¹⁸; P{GD2777}v47544

v342012

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01364}attP40/CyO-GFP

Genomic Clones (7)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (44)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

AT02150

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0025702

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0025702

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Nieratschker et al., 2009)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

Identification: cDNA screen for secreted and transmembrane proteins expressed during embryogenesis.

(Kopczynski et al., 1998)

Relationship to Other Genes

Source for database merge of

Source for merge of: BEST:CK01209 CG9085

(Bayraktaroglu, 2000.11.2)

Source for merge of: BEST:CK01209 CG11489

(FlyBase, 1996-)

Additional comments

Source for merge of BEST:CK01209 CG11489 was a shared cDNA ( date:010720 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: srpk79D CG11489

(Johnson et al., 2009)

Source for identity of: Srpk79D srpk79D

(FlyBase, 2009-)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (15)

Reported As

Symbol Synonym

BEST:CK01209

(Giot et al., 2003, Egger et al., 2002)

CG11489

(Lee et al., 2022, Neuert et al., 2017, Abruzzi et al., 2011, Ni et al., 2010.12.1, Johnson et al., 2009, Keleman et al., 2009.8.5, Nieratschker et al., 2009, Ayres et al., 2008, Choksi et al., 2006)

CG9085

(Artero et al., 2003, Allemand et al., 2001, Anholt and Mackay, 2001, Mount and Salz, 2000)

CK01209

(Kopczynski et al., 1998)

SRPK

(Artero et al., 2003)

SRPK1

(Morrison et al., 2000)

SRPK79D

(Mercier et al., 2023, Zhang et al., 2016)

Srpk79D

(Ding et al., 2022, Ostalé et al., 2021, Böhme et al., 2019, Meltzer et al., 2019, Neuert et al., 2017, Transgenic RNAi Project members, 2017-, Nieratschker et al., 2009)

atc

(Johnson et al., 2009)

srpk79D

(Driller et al., 2019, Gene Disruption Project members, 2016-, Siebert et al., 2015, Saccone et al., 2014, Johnson et al., 2009)

srpk79d

(Mosca et al., 2017)

Name Synonyms

Serine-arginine protein kinase at 79D

air traffic controller

(Johnson et al., 2009)

serine-arginine (SR) protein kinase at location 79D

(Siebert et al., 2015)

serine-arginine protein kinase at 79D

(Johnson et al., 2009)

Secondary FlyBase IDs

FBgn0037157
FBgn0037158

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 81 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40461

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

M9NGC6

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

M9NGC6

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0025702

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40461/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0025702

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0025702

FlyMine - An integrated database for Drosophila genomics

FBgn0025702

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG11489

MARRVEL_MODEL - MARRVEL (model organism gene)

40461

Linkouts

BioGRID - A database of protein and genetic interactions.

65697

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0025702

DroID - A comprehensive database of gene and protein interactions.

FBgn0025702

DRSC - Results frm RNAi screens

FBgn0025702

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0025702

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0025702

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11489

Flygut - An atlas of the Drosophila adult midgut

FBgn0025702

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q8SWX7

References (68)

The following external sites may use different assemblies or annotations than FlyBase.

2.77

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