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Gene Dmel\CG13920

General Information
Symbol	Dmel\CG13920	Species	D. melanogaster
Name		Annotation symbol	CG13920
Feature type	protein_coding_gene	FlyBase ID	FBgn0025712
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	62A9-62A9	Sequence location	3L:1,649,006..1,651,501 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG13920 (FBgn0025712). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult hindgut, adult heart. Comments on Affy2 ProbeSet: ProbeSet 1628678_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG13920. Gene sequence location is 3L:1649006..1651501.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 62A9-62A9   Limits computationally determined from genome sequence between P{EP}rhoEP3704&P{PZ}l(3)0622606226 and P{PZ}dlt04276
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG13920 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.44
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG13920-RA FBtr0072761  NM_139382   1230   160
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG13920-PA   FBpp0072644   17.9   160   10.19     NP_647639   AAF47539
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140907   AA142269   AE014296 AAF47539   AI108384   AI113673   AI402067   AI520036   AY069059 AAL39204   BI230911   BI231593   BI564124   BI565362   BI567690   BI569818   BI569834   BI576559   BI576715   BI585222   BI586973   BI587866   BI588258   BI604890   BI605312   BI606433   BI610442   BI615522   BI619905   BI627072   BI627779   BI628668   CO277064   CO290999   CO312921   CZ468140   EC058969   EC060226   EC065099   EC075465   EC080568   EC225491   EL870631   EL870635
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T0T9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   central brain primordium   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic central brain neuron   (Fisher et al., 2012) embryonic/larval nervous system   (Fisher et al., 2012) lateral cord neuron   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult hindgut, adult heart. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    819.35 Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass    536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain    844 Adult Thoracic-Abdominal Ganglion    859.4 Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass    563.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (819.35) Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass  536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain  (844) Adult Thoracic-Abdominal Ganglion  (859.4) Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass  (563.4) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    819.35 Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass    536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain    844 Adult Thoracic-Abdominal Ganglion    859.4 Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass    563.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    819.35 Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass    536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain    844 Adult Thoracic-Abdominal Ganglion    859.4 Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass    563.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    819.35 Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass    536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain    844 Adult Thoracic-Abdominal Ganglion    859.4 Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass    563.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (819.35) Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass  536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain  (844) Adult Thoracic-Abdominal Ganglion  (859.4) Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass  563.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    819.35 Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass    536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain    844 Adult Thoracic-Abdominal Ganglion    859.4 Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass    563.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    819.35 Larval Midgut    50.9 Larval Hindgut    85.1 Larval Malpighian Tubules    13.7 Larval Fat Body    7.9 Larval Salivary Gland    6.8 Larval Trachea    21.6 Larval Carcass    536.575 Adult Head    415.4 Adult Eye    164.25 Adult Brain    844 Adult Thoracic-Abdominal Ganglion    859.4 Adult Crop    306.9 Adult Midgut    81.1 Adult Hindgut    136 Adult Malpighian Tubules    12.8 Adult Fat Body    10.9 Adult Salivary Gland    4.9 Adult Heart    361.225 Adult VirginFemale Spermatheca    7.8 Adult InseminatedFemale Spermatheca    15.2 Adult Ovary    13 Adult Testis    23.1 Adult Male Accessory Gland    91.8 Adult Carcass    563.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    415.4   NA  Eye    164.25   NA  Brain    844   819.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    859.4   NA  Crop    306.9   50.9  Midgut    81.1   85.1  Hindgut    136   no informative data  Malpighian Tubules    no informative data   7.9  Fat Body    no informative data   6.8  Salivary Gland    4.9   NA  Heart    361.225   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    7.8   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    no informative data   NA  Testis    23.1   NA  Male Accessory Gland    91.8   536.575  Carcass    563.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    80 central nervous system, pupae P8    141 head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3  (80) central nervous system, pupae P8  (141) head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    80 central nervous system, pupae P8  (141) head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    80 central nervous system, pupae P8    141 head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    80 central nervous system, pupae P8    141 head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3  (80) central nervous system, pupae P8  (141) head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    80 central nervous system, pupae P8  141 head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    4 central nervous system, larvae L3    80 central nervous system, pupae P8    141 head, virgin 1-day female    18 head, virgin 4-day female    11 head, virgin 20-day female    9 head, mated 1-day female    12 head, mated 4-day female    12 head, mated 20-day female    9 head, mated 1-day male    19 head, mated 4-day male    20 head, mated 20-day male    14 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    11 carcass, 1-day adult    15 carcass, 4-day adult    12 carcass, 20-day adult    4 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    33 embryo 08-10hr    75 embryo 10-12hr    126 embryo 12-14hr    95 embryo 14-16hr    69 embryo 16-18hr    47 embryo 18-20hr    41 embryo 20-22hr    53 embryo 22-24hr    53 larva L1    28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP    59 pupae 3d postWPP    49 pupae 4d postWPP    101 adult male 01day    37 adult male 05day    29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr  (33) embryo 08-10hr  (75) embryo 10-12hr  (126) embryo 12-14hr  (95) embryo 14-16hr  (69) embryo 16-18hr  (47) embryo 18-20hr  (41) embryo 20-22hr  (53) embryo 22-24hr  (53) larva L1  (28) larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9  26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP  (59) pupae 3d postWPP  (49) pupae 4d postWPP  (101) adult male 01day  (37) adult male 05day  (29) adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    33 embryo 08-10hr    75 embryo 10-12hr  (126) embryo 12-14hr    95 embryo 14-16hr    69 embryo 16-18hr    47 embryo 18-20hr    41 embryo 20-22hr    53 embryo 22-24hr    53 larva L1    28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP    59 pupae 3d postWPP    49 pupae 4d postWPP  101 adult male 01day    37 adult male 05day    29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    33 embryo 08-10hr    75 embryo 10-12hr    126 embryo 12-14hr    95 embryo 14-16hr    69 embryo 16-18hr    47 embryo 18-20hr    41 embryo 20-22hr    53 embryo 22-24hr    53 larva L1    28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP    59 pupae 3d postWPP    49 pupae 4d postWPP    101 adult male 01day    37 adult male 05day    29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    33 embryo 08-10hr    75 embryo 10-12hr    126 embryo 12-14hr    95 embryo 14-16hr    69 embryo 16-18hr    47 embryo 18-20hr    41 embryo 20-22hr    53 embryo 22-24hr    53 larva L1    28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP    59 pupae 3d postWPP    49 pupae 4d postWPP    101 adult male 01day    37 adult male 05day    29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr  (33) embryo 08-10hr  (75) embryo 10-12hr  (126) embryo 12-14hr  (95) embryo 14-16hr  (69) embryo 16-18hr  (47) embryo 18-20hr  (41) embryo 20-22hr  (53) embryo 22-24hr  (53) larva L1  28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9  26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP  (59) pupae 3d postWPP  (49) pupae 4d postWPP  (101) adult male 01day  (37) adult male 05day  29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    33 embryo 08-10hr    75 embryo 10-12hr  126 embryo 12-14hr    95 embryo 14-16hr    69 embryo 16-18hr    47 embryo 18-20hr    41 embryo 20-22hr    53 embryo 22-24hr    53 larva L1    28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP    59 pupae 3d postWPP    49 pupae 4d postWPP  101 adult male 01day    37 adult male 05day    29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    3 embryo 04-06hr    4 embryo 06-08hr    33 embryo 08-10hr    75 embryo 10-12hr    126 embryo 12-14hr    95 embryo 14-16hr    69 embryo 16-18hr    47 embryo 18-20hr    41 embryo 20-22hr    53 embryo 22-24hr    53 larva L1    28 larva L2    20 larva L3 12hr old    15 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    22 white prepupae 12hr    22 white prepupae 24hr    21 pupae 2d postWPP    59 pupae 3d postWPP    49 pupae 4d postWPP    101 adult male 01day    37 adult male 05day    29 adult male 30day    19 adult female 01day    18 adult female 05day    5 adult female 30day    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    7 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    8 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    7 Ethanol 5% 3 hrs, larvae L3    15 Ethanol 10% 3 hrs, larvae L3    13 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    8 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    14 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_29
External Data & Images
Linkouts	BDGP expression data • GH07209 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025712 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13920-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG13920 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal CG13920CC01646 viable, with Scer\GAL4pnr-MD237 CG13920GD3827 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG13920 Class Mutagen Stocks Known lesion CG13920c02683 piggyBac transposase 0 -- CG13920CC01646 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG13920 Class Mutagen Stocks Known lesion CG13920GD3827 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG13920KK109369 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3827} NA P{KK109369} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GC}CG13920CC01646 NA PBac{PB}CG13920c02683 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG13920 - CG15098 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG13920 - Sas-4 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG13920 - sas-6 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG13920 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0025712 DroID - A comprehensive database of gene and protein interactions. • FBgn0025712
Orthologs
OrthoDB Orthologs (43) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6BVSF9 Dipteran inclusive ortholog search EOG6JDHH6 Insect inclusive ortholog search EOG6JQ2V5 Arthropod inclusive ortholog search EOG676HGR Metazoa inclusive ortholog search EOG6XDGM5
Orthologs in Drosophila Species (EOG6BVSF9)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG13920     Drosophila simulans   Dsim\GD13635 Y   Drosophila sechellia   Dsec\GM14433 Y   Drosophila erecta   Dere\GG14811 Y   Drosophila yakuba   Dyak\GE21174 Y   Drosophila ananassae   Dana\GF24822 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA12626 Y   Drosophila persimilis   Dper\GL11921 Y   Drosophila willistoni   Dwil\GK24408 Y   Drosophila virilis   Dvir\GJ12864 Y   Drosophila mojavensis   Dmoj\GI16610 Y   Drosophila grimshawi   Dgri\GH15957 Y
Orthologs in non-Drosophila Dipterans (EOG6JDHH6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL015672   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009300   Anopheles gambiae Malaria mosquito  Agam\AGAP007501   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008615
Orthologs in non-Dipteran Insects (EOG6JQ2V5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47109   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005353   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22930   Atta cephalotes Leafcutter ant  Acep\ACEP26920   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17322   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15105   Linepithema humile Argentine ant  Lhum\LH16948   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23553   Solenopsis invicta Red fire ant  Sinv\SINV24554   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007527   Pediculus humanus Human body louse  Phum\PHUM601180   Tribolium castaneum Red flour beetle  Tcas\TC013786
Orthologs in non-Insect Arthropods (EOG676HGR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW021886
Orthologs in non-Arthropod Metazoa (EOG6XDGM5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006766gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015600gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025508gn   Danio rerio Zebrafish  Drer\tmem35   Xenopus tropicalis Western clawed frog  Xtro\tmem35   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000007096   Gallus gallus Domestic chicken  Ggal\TMEM35   Gallus gallus Domestic chicken  Ggal\ZMYM6NB   Mus musculus House mouse  Mmus\Gm12942   Mus musculus House mouse  Mmus\Tmem35   Rattus norvegicus Norway rat  Rnor\Tmem35   Rattus norvegicus Norway rat  Rnor\Zmym6nb   Homo sapiens Human  Hsap\ZMYM6NB   Homo sapiens Human  Hsap\TMEM35
Human Orthologs (2)
Gene OMIM HGNC Hsap\ZMYM6NB     Hsap\TMEM35
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13635 Drosophila sechellia Dsec\GM14433 Drosophila erecta Dere\GG14811 Drosophila yakuba Dyak\GE21174 Drosophila ananassae Dana\GF24822 Drosophila pseudoobscura pseudoobscura Dpse\GA12626 Drosophila persimilis Dper\GL11921 Drosophila willistoni Dwil\GK24408 Drosophila virilis Dvir\GJ12864 Drosophila mojavensis Dmoj\GI16610 Drosophila grimshawi Dgri\GH15957
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v105183 P{KK109369}VIE-260B v46993 w1118; P{GD3827}v46993 v46995 w1118; P{GD3827}v46995
Genomic Clones ( 2 )
	BACR14O14 BACR17K18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 39 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH07209
Other clones	DPiM_GH07209
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH10085 LD39965 RE16177 RE22476 RH01973 RH01992 RH15931 RH24777 RH27217 RH28760 RH29407 RH33146 RH33333 RH35836 RH38244 RH45189 RH51042 RH57173 RH63122 RH68267 RH69209 RH70385 RH70893 RH72912
Other clones	1592 77210 104993 105544 CK01.40A.E3 CK01.97D.E6 CK00246 CK00551 EK075751 EK122821 EK230547 IP02701 IP02704
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0025712 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38203
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: BEST:CK00246 CG13920 (Bayraktaroglu, 2000.11.2)
Additional comments
Other Comments
	Identification: cDNA screen for secreted and transmembrane proteins expressed during embryogenesis. (Kopczynski et al., 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139382 RefSeq (Proteins) • NP_647639 DDBJ / EMBL / GenBank • AA142269 AAF47539 AAL39204 AI108384 AI402067 AY069059 CZ468140 Entrez Gene - A searchable database of RefSeq genes. • 38203 UniProtKB/TrEMBL • Q8T0T9
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH07209
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0025712 DroID - A comprehensive database of gene and protein interactions. • FBgn0025712 DRSC - Results from RNAi screens. • FBgn0025712 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025712 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13920-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0025712 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38203 modMine - Data generated by the modENCODE project. • FBgn0025712
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BEST:CK00246   CG13920 (Buszczak et al., 2007, Toledano-Katchalski et al., 2007, Keleman et al., 2009.8.5, Cammarato et al., 2011) CK00246 (Kopczynski et al., 1998)
Name Synonym
Secondary FlyBase IDs
	FBgn0035250
References ( 19 )
Research paper	Buszczak et al., 2007, Genetics 175(3): 1505--1531 The Carnegie protein trap library: A versatile tool for Drosophila developmental studies. [FBrf0200345] Toledano-Katchalski et al., 2007, Development 134(19): 3473--3481 Post-transcriptional repression of the Drosophila midkine and pleiotrophin homolog miple by HOW is essential for correct mesoderm spreading. [FBrf0201671] Kuzin et al., 2005, Dev. Biol. 277(2): 347--365 Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS. [FBrf0183075] Brody et al., 2002, Mech. Dev. 113(1): 41--59 Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. [FBrf0147137] Kopczynski et al., 1998, Proc. Natl. Acad. Sci. U.S.A. 95(17): 9973--9978 A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. [FBrf0104467]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] Bayraktaroglu, 2000.11.2, Current list of possibly CG-able known genes. Current list of possibly CG-able known genes. [FBrf0131225] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]