FB2021_01, released Feb 18, 2021

Gene: Dmel\homer

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General Information
Symbol
Dmel\homer
Species
D. melanogaster
Name
homer
Annotation Symbol
CG11324
Feature Type
protein_coding_gene
FlyBase ID
FBgn0025777
Gene Model Status
Current
Stock Availability
11 publicly available
Gene Snapshot
homer (homer) encodes a protein that acts as an adaptor protein binding to group I metabotropic glutamate receptors and other intracellular signaling proteins. It contributes to regulation of sleep, locomotor activity and ethanol tolerance. [Date last reviewed: 2019-03-07]
Other Summaries
Also Known As

Dhomer

Key Links
Genomic Location
Cytogenetic map
27A1-27A1
Sequence location
2L:6,719,394..6,723,359 [-]
Recombination map

2-22

RefSeq locus
NT_033779 REGION:6719394..6723359
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (13 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables protein binding
inferred from physical interaction with FLYBASE:Prosap; FB:FBgn0040752
(Diagana et al., 2002)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables G protein-coupled glutamate receptor binding
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (7 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
involved_in adult behavior
inferred from mutant phenotype
(Diagana et al., 2002)
involved_in behavioral response to ethanol
inferred from mutant phenotype
(Urizar et al., 2007)
involved_in positive regulation of circadian sleep/wake cycle, sleep
inferred from mutant phenotype
(Naidoo et al., 2012)
involved_in regulation of locomotion
inferred from mutant phenotype
(Diagana et al., 2002)
involved_in response to ethanol
inferred from direct assay
(Urizar et al., 2007)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in G protein-coupled glutamate receptor signaling pathway
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in regulation of store-operated calcium entry
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in dendrite
inferred from direct assay
(Rolls et al., 2007, Diagana et al., 2002)
located_in endoplasmic reticulum
inferred from direct assay
(Diagana et al., 2002)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in dendrite
inferred from biological aspect of ancestor with PANTHER:PTN000857489
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in plasma membrane
inferred from biological aspect of ancestor with PANTHER:PTN000857479
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Summary (Interactive Fly)

scaffolding protein required for the function of neural networks controlling locomotor activity and behavioral plasticity

Gene Model and Products
Number of Transcripts
6
Number of Unique Polypeptides
5

Please see the JBrowse view of Dmel\homer for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.45

Stop-codon suppression (UGA) postulated; FBrf0216885.

Gene model reviewed during 5.44

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene
gene_with_stop_codon_read_through
(Jungreis, 2011.11.18)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
homer-RA
FBtr0079306
NM_058048
1921
394
homer-RB
FBtr0079307
NM_164706
2388
397
homer-RD
FBtr0329892
NM_001273221
2923
394
homer-RE
FBtr0329893
NM_001042876
1921
531
homer-RF
FBtr0332330
NM_001273223
1930
397
homer-RG
FBtr0333346
NM_001273222
2397
400
Additional Transcript Data and Comments
Reported size (kB)

1.9 (longest cDNA)

(Xiao et al., 1998)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
homer-PA
FBpp0078936
42.7
394
7.58
NP_477396
AAF52428
homer-PB
FBpp0078937
43.0
397
7.18
NP_723207
AAF52429
homer-PD
FBpp0302926
42.7
394
7.58
NP_001260150
AGB92686
homer-PE
FBpp0302927
57.3
531
9.02
NP_001036341
ABI31295
homer-PF
FBpp0304608
43.0
397
7.58
NP_001260152
AGB92688
homer-PG
FBpp0305538
43.4
400
7.58
NP_001260151
AGB92687
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

394 aa isoforms: homer-PA, homer-PD
Additional Polypeptide Data and Comments
Reported size (kDa)

394 (aa)

(Xiao et al., 1998)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\homer using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 12 -- 17
presumptive embryonic/larval central nervous system
(Diagana et al., 2002)
presumptive embryonic/larval peripheral nervous system
(Diagana et al., 2002)
scolopidial neuron
(Diagana et al., 2002)
bipolar dendrite neuron
(Diagana et al., 2002)
embryonic stage 16 -- 17
embryonic/larval central nervous system
(Diagana et al., 2002)
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 11 -- 12
anterior midgut primordium
(Fisher et al., 2012)
central brain primordium
(Fisher et al., 2012)
embryonic central brain glial cell
(Fisher et al., 2012)
embryonic central brain neuron
(Fisher et al., 2012)
lateral cord glial cell
(Fisher et al., 2012)
lateral cord neuron
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior midgut primordium
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
embryonic/larval midgut
(Fisher et al., 2012)
embryonic/larval nervous system
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
ventral nerve cord
(Fisher et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 16 -- 17
neuropil of ventral nerve cord
(Diagana et al., 2002)
neuron of ventral nerve cord
(Diagana et al., 2002)
larval stage
embryonic/larval central nervous system
(Diagana et al., 2002)
pupal stage -- adult stage
adult central nervous system
(Diagana et al., 2002)
lamina
(Diagana et al., 2002)
medulla
(Diagana et al., 2002)
embryonic stage 12 -- 17
scolopidial neuron
(Diagana et al., 2002)
sensory neuron
(Diagana et al., 2002)
adult stage
adult brain | restricted
(Urizar et al., 2007)
ellipsoid body
(Urizar et al., 2007)
fan-shaped body
(Urizar et al., 2007)
adult central complex
(Urizar et al., 2007)
adult antennal lobe
(Urizar et al., 2007)
adult optic lobe | restricted
(Urizar et al., 2007)
protocerebral bridge
(Urizar et al., 2007)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Diagana et al., 2002)
Additional Descriptive Data

homer expression in the dorsal neuropil of the embryonic ventral nerve cord overlaps that of synaptotagmin, suggesting synaptic localization.

(Diagana et al., 2002)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in dendrite
inferred from direct assay
(Rolls et al., 2007, Diagana et al., 2002)
located_in endoplasmic reticulum
inferred from direct assay
(Diagana et al., 2002)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\homer in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 11 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of homer
Transgenic constructs containing regulatory region of homer
Aberrations (Deficiencies and Duplications) ( 2 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (3)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\HOMER2
15 of 15
Yes
Yes
2  
Hsap\HOMER1
10 of 15
No
Yes
1  
Hsap\HOMER3
8 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (3)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Homer2
14 of 15
Yes
Yes
Mmus\Homer1
10 of 15
No
Yes
Mmus\Homer3
8 of 15
No
Yes
Rattus norvegicus (Norway rat) (3)
Rnor\Homer2
10 of 13
Yes
Yes
Rnor\Homer1
8 of 13
No
Yes
Rnor\Homer3
8 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (3)
Xtro\homer2
11 of 12
Yes
Yes
Xtro\homer1
9 of 12
No
Yes
Xtro\homer3
4 of 12
No
Yes
Danio rerio (Zebrafish) (4)
Drer\homer1b
10 of 15
Yes
Yes
Drer\homer3b
5 of 15
No
Yes
Drer\LOC100330028
5 of 15
No
Yes
Drer\homer2
4 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (0)
No records found.
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPBC800.10c
1 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190807 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00001464
Drosophila simulans
Dsim\GD22547
Drosophila sechellia
Dsec\GM13902
Drosophila erecta
Dere\GG23589
Drosophila yakuba
Dyak\GE18410
Drosophila ananassae
Dana\GF14950
Drosophila pseudoobscura pseudoobscura
Dpse\GA10919
Drosophila persimilis
Dper\GL25967
Drosophila willistoni
Dwil\GK24217
Drosophila virilis
Dvir\GJ15454
Drosophila mojavensis
Dmoj\GI17542
Drosophila grimshawi
Dgri\GH11023
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150863 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17021114
Glossina morsitans
Tsetse fly
Gmor\GMOY008366
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_07905
Mayetiola destructor
Hessian fly
Mdes\Mdes007819
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL011093
Anopheles darlingi
American malaria mosquito
Adar\ADAC005156
Anopheles gambiae
Malaria mosquito
Agam\AGAP010076
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ009183
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W08Q6 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA013976
Bombyx mori
Silkmoth
Bmor\BGIBMGA013977
Danaus plexippus
Monarch butterfly
Dple\DPOGS211731-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL017342
Apis florea
Little honeybee
Aflo\2770405204
Apis mellifera
Western honey bee
Amel\GB43427
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP20287
Bombus terrestris
Buff-tailed bumblebee
Bter\15214681
Linepithema humile
Argentine ant
Lhum\LH12404
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001d98
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007964
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_13055
Tribolium castaneum
Red flour beetle
Tcas\TC015941
Pediculus humanus
Human body louse
Phum\PHUM370830
Rhodnius prolixus
Kissing bug
Rpro\RPRC014639
Cimex lectularius
Bed bug
Clec\CLEC010018
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002138
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_09175
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X08LT )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR011818
Ixodes scapularis
Black-legged tick
Isca\ISCW001721
Stegodyphus mimosarum
African social velvet spider
Smim\KFM69654.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM60448.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur12g01940
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_300115
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0CQ0 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Homer2
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000013854
Gallus gallus
Domestic chicken
Ggal\HOMER3
Gallus gallus
Domestic chicken
Ggal\HOMER1
Gallus gallus
Domestic chicken
Ggal\HOMER2
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 1 )
Human Ortholog
Disease
Evidence
References
HOMER2; homer scaffold protein 2
model of  autosomal dominant nonsyndromic deafness 68
IEA
(FlyBase, 2019-)
Modifiers Based on Experimental Evidence ( 0 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
HOMER2; homer scaffold protein 2
15 of 15
604799
 
HOMER1; homer scaffold protein 1
10 of 15
604798
       
      HOMER3; homer scaffold protein 3
      8 of 15
      604800
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          esyN Network Diagram
          Show neighbor-neighbor interactions:
          Select Layout:
          Legend:
          Protein
          RNA
          Selected Interactor(s)
          Interactions Browser
          View in Interactions Browser
          Please see the Physical Interaction reports below for full details
          protein-protein
          Physical Interaction
          Assay
          References
          homer - CG32264
          anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
          (Rhee et al., 2014)
          homer - Prosap
          two hybrid
          (Diagana et al., 2002)
          homer - mGluR
          anti bait coimmunoprecipitation, western blot
          (Ly et al., 2020)
          Summary of Genetic Interactions
          esyN Network Diagram
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          2L
          Recombination map

          2-22

          Cytogenetic map
          27A1-27A1
          Sequence location
          2L:6,719,394..6,723,359 [-]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          27A1-27A1
          Limits computationally determined from genome sequence between P{EP}Sec61αEP2180 and P{lacW}Ate1k10809
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location

          2-22

          (FlyBase, 2016)

          2-21.6

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (11)
          Genomic Clones (17)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (82)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           

          polyclonal

          (Diagana et al., 2002)
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of

          Source for identity of: homer CG11324

          (Wortman, 1999.11)
          Source for database merge of

          Source for merge of: homer BEST:LD03829

          (Bayraktaroglu, 2000.11.2)
          Additional comments
          Other Comments

          dsRNA made from templates generated with primers against this gene used in a genome-wide dsRNA interference (RNAi) screen to identify regulators of the signalling pathway leading from Ca2+-calcineurin to NFAT.

          (Gwack et al., 2006)

          dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

          (Kiger et al., 2003)

          homer operates in the ER and in dendrites to regulate the development and function of neural networks underlying locomotor control and behavioral plasticity.

          (Diagana et al., 2002)

          Mutants display defects in behavioural plasticity and the control of locomotor activity.

          (Diagana et al., 2002)

          Identification: Homer 1a sequence (from rat) was used to search GenBank databases, Drosophila sequence was identified.

          (Xiao et al., 1998)
          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 59 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          modMine - A data warehouse for the modENCODE project
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DPiM - Drosophila Protein interaction map
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          FlyMine - An integrated database for Drosophila genomics
          Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Synonyms and Secondary IDs (13)
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