Dhomer
scaffolding protein required for the function of neural networks controlling locomotor activity and behavioral plasticity
Please see the JBrowse view of Dmel\homer for information on other features
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Gene model reviewed during 5.45
Stop-codon suppression (UGA) postulated; FBrf0216885.
Gene model reviewed during 5.44
Gene model reviewed during 5.46
1.9 (longest cDNA)
394 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\homer using the Feature Mapper tool.
Comment: maternally deposited
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
homer expression in the dorsal neuropil of the embryonic ventral nerve cord overlaps that of synaptotagmin, suggesting synaptic localization.
GBrowse - Visual display of RNA-Seq signals
View Dmel\homer in GBrowse 22-22
2-22
2-21.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: homer CG11324
Source for merge of: homer BEST:LD03829
dsRNA made from templates generated with primers against this gene used in a genome-wide dsRNA interference (RNAi) screen to identify regulators of the signalling pathway leading from Ca2+-calcineurin to NFAT.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
homer operates in the ER and in dendrites to regulate the development and function of neural networks underlying locomotor control and behavioral plasticity.
Mutants display defects in behavioural plasticity and the control of locomotor activity.
Identification: Homer 1a sequence (from rat) was used to search GenBank databases, Drosophila sequence was identified.