TDP-43, dTDP-43, dTDP
RNA-binding protein - regulation of synaptic efficacy and motor control - regulation of Futsch activity at the neuromuscular junction - regulation of the robustness of neuronal specification through microRNA-9a - a model for Amyotrophic lateral sclerosis (ALS), often referred to as Lou Gehrig's Disease
Gene model reviewed during 5.52
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa.
3.166, 1.916, 1.638 (longest cDNA)
531, 332 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\TBPH using the Feature Mapper tool.
TBPH protein is expressed in the nuclei of neurons, glia, and muscle cells throughout development, including in muscle cells of wandering third instar larvae, and in both neurons and glial cells of the adult brain. TBPH protein can be detected in the perinuclear region of post-mitotic neurons of the adult ellipsoid body.
GBrowse - Visual display of RNA-Seq signalsView Dmel\TBPH in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: TBPH CG10327