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Gene Dmel\Mgstl

General Information
Symbol	Dmel\Mgstl	Species	D. melanogaster
Name	Microsomal glutathione S-transferase-like	Annotation symbol	CG1742
Feature type	protein_coding_gene	FlyBase ID	FBgn0025814
Gene Model Status	Current	Stock availability	9 publicly available
Also Known As	Mgst1
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	19E7-19E7	Sequence location	X:20,913,512..20,915,134 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Microsomal glutathione S-transferase-like is referred to in FlyBase by the symbol Dmel\Mgstl (CG1742, FBgn0025814). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: glutathione transferase activity. The biological processes in which it is involved are not known. 19 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; tarsal segment; wing; arista; scutellum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Membrane associated eicosanoid/glutathione metabolism-like domain; Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult hindgut, adult heart, adult fat body, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1627643_at completely aligns to an exonic region of only a subset of 1 of the 2 FlyBase-annotated transcript isoforms of Mgstl. Gene sequence location is X:20913512..20915134.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 19E7-19E7   Limits computationally determined from genome sequence between P{EP}CG1702EP1525 and P{EP}EP1465&P{EP}CG1486EP1192
Experimentally Determined Cytological Location
Cytogenetic map Notes References 19E-19E     (Toba, 1998.12.4) 19E-19E     (Toba, 1998.12.4) 19E-19E   (determined by in situ hybridisation)   (Toba et al., 1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Mgstl for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Mgstl-RA FBtr0077243  NM_079957   660   152 Mgstl-RB FBtr0077242  NM_167724   591   151
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Mgstl-PA   FBpp0076936   16.9   152   10.59     NP_524696   AAF50864 Mgstl-PB   FBpp0076935   16.8   151   9.50     NP_728382   AAN09527
Additional Polypeptide Data & Comments
Reported size (kDa)	152 (aa) (Toba et al., 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein (IPR001129) Membrane associated eicosanoid/glutathione metabolism-like domain (IPR023352) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME01742
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF50864   AE014298 AAN09527   AF111426 AAC98692   AF111428 AAC98694   AI297817   AI386976   AI389997   AI390003   AI404989   AY071752 AAL49374   AY075452 AAL68265   BI169509   BI169775   BI233187   BI243938   BI563441   BI564603   BI564981   BI565549   BI568264   BI575400   BI584118   BI584468   BI585960   BI587509   BI612952   BI613017   BI616858   BI616909   BI618343   BI618655   BI627843   BI630498   BP554126   BP554127   BQ103486   BT024937   BT120131   BT120306   BT125799   CO154310   CO154743   CO179925   CO180423   CO195957   CO264690   CZ477173   EC194848   EC244349   EC261945   EL875788   EL879672   EL884965   EL884966   EL885093   EL885094   EV581460   EV590764   EV598913   GH941164   GH941919   GH960285   GH962532   GH967114   GH968095   GH979740   GH981745
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SY19 Q8SY70 O97471
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 1 -- 5   organism | ubiquitous   (Toba and Aigaki, 2000) Comment:maternally supplied embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 6 -- 14   organism | ubiquitous   (Toba and Aigaki, 2000) Comment:enriched in specific tissues fat body   (Toba and Aigaki, 2000) Comment:enriched embryonic stage 13 -- 16   embryonic midgut chamber   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) larval stage   imaginal disc   (Toba and Aigaki, 2000) embryonic/larval central nervous system | faint   (Toba and Aigaki, 2000) RT-PCR Stage Tissue/Position (including subcellular localization) Reference third instar larval stage -- adult stage   organism   (Toba and Aigaki, 2000)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult hindgut, adult heart, adult fat body, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.625 Larval Midgut    4 Larval Hindgut    0.7 Larval Malpighian Tubules    3.9 Larval Fat Body    10.4 Larval Salivary Gland    1.4 Larval Trachea    3.15 Larval Carcass    2.225 Adult Head    275.5 Adult Eye    212.075 Adult Brain    13.4 Adult Thoracic-Abdominal Ganglion    10.7 Adult Crop    9.7 Adult Midgut    62.1 Adult Hindgut    133 Adult Malpighian Tubules    11 Adult Fat Body    109.5 Adult Salivary Gland    10.1 Adult Heart    103.525 Adult VirginFemale Spermatheca    14.8 Adult InseminatedFemale Spermatheca    9.2 Adult Ovary    3.6 Adult Testis    4.2 Adult Male Accessory Gland    14 Adult Carcass    257.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    275.5   NA  Eye    212.075   NA  Brain    13.4   1.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    9.7   4  Midgut    62.1   0.7  Hindgut    133   3.9  Malpighian Tubules    no informative data   no informative data  Fat Body    109.5   1.4  Salivary Gland    no informative data   NA  Heart    103.525   3.15  Trachea    NA   NA  VirginFemale Spermatheca    14.8   NA  InseminatedFemale Spermatheca    9.2   NA  Ovary    3.6   NA  Testis    4.2   NA  Male Accessory Gland    no informative data   2.225  Carcass    257.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    102 central nervous system, larvae L3    66 central nervous system, pupae P8    50 head, virgin 1-day female    155 head, virgin 4-day female    91 head, virgin 20-day female    171 head, mated 1-day female    85 head, mated 4-day female    72 head, mated 20-day female    123 head, mated 1-day male    182 head, mated 4-day male    159 head, mated 20-day male    206 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    61 digestive system, 1-day adult    158 digestive system, 4-day adult    102 digestive system, 20-day adult    135 fat body, larvae L3 wandering    218 fat body, white prepupae    23 fat body, pupae P8    71 carcass, larvae L3 wandering    46 carcass, 1-day adult    204 carcass, 4-day adult    244 carcass, 20-day adult    254 ovary, virgin 4-day female    153 ovary, mated 4-day female    142 testis, mated 4-day male    30 accessory gland, mated 4-day male    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (102) central nervous system, larvae L3  (66) central nervous system, pupae P8  (50) head, virgin 1-day female  (155) head, virgin 4-day female  (91) head, virgin 20-day female  (171) head, mated 1-day female  (85) head, mated 4-day female  (72) head, mated 20-day female  (123) head, mated 1-day male  (182) head, mated 4-day male  (159) head, mated 20-day male  (206) salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering  (61) digestive system, 1-day adult  (158) digestive system, 4-day adult  (102) digestive system, 20-day adult  (135) fat body, larvae L3 wandering  (218) fat body, white prepupae    23 fat body, pupae P8  (71) carcass, larvae L3 wandering  (46) carcass, 1-day adult  (204) carcass, 4-day adult  (244) carcass, 20-day adult  (254) ovary, virgin 4-day female  (153) ovary, mated 4-day female  (142) testis, mated 4-day male  (30) accessory gland, mated 4-day male  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  102 central nervous system, larvae L3    66 central nervous system, pupae P8    50 head, virgin 1-day female  (155) head, virgin 4-day female    91 head, virgin 20-day female  (171) head, mated 1-day female    85 head, mated 4-day female    72 head, mated 20-day female  (123) head, mated 1-day male  (182) head, mated 4-day male  (159) head, mated 20-day male  (206) salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    61 digestive system, 1-day adult  (158) digestive system, 4-day adult  102 digestive system, 20-day adult  (135) fat body, larvae L3 wandering  (218) fat body, white prepupae    23 fat body, pupae P8    71 carcass, larvae L3 wandering    46 carcass, 1-day adult  (204) carcass, 4-day adult  (244) carcass, 20-day adult  (254) ovary, virgin 4-day female  (153) ovary, mated 4-day female  (142) testis, mated 4-day male    30 accessory gland, mated 4-day male    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    102 central nervous system, larvae L3    66 central nervous system, pupae P8    50 head, virgin 1-day female    155 head, virgin 4-day female    91 head, virgin 20-day female    171 head, mated 1-day female    85 head, mated 4-day female    72 head, mated 20-day female    123 head, mated 1-day male    182 head, mated 4-day male    159 head, mated 20-day male    206 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    61 digestive system, 1-day adult    158 digestive system, 4-day adult    102 digestive system, 20-day adult    135 fat body, larvae L3 wandering    218 fat body, white prepupae    23 fat body, pupae P8    71 carcass, larvae L3 wandering    46 carcass, 1-day adult    204 carcass, 4-day adult    244 carcass, 20-day adult    254 ovary, virgin 4-day female    153 ovary, mated 4-day female    142 testis, mated 4-day male    30 accessory gland, mated 4-day male    35 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    102 central nervous system, larvae L3    66 central nervous system, pupae P8    50 head, virgin 1-day female    155 head, virgin 4-day female    91 head, virgin 20-day female    171 head, mated 1-day female    85 head, mated 4-day female    72 head, mated 20-day female    123 head, mated 1-day male    182 head, mated 4-day male    159 head, mated 20-day male    206 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    61 digestive system, 1-day adult    158 digestive system, 4-day adult    102 digestive system, 20-day adult    135 fat body, larvae L3 wandering    218 fat body, white prepupae    23 fat body, pupae P8    71 carcass, larvae L3 wandering    46 carcass, 1-day adult    204 carcass, 4-day adult    244 carcass, 20-day adult    254 ovary, virgin 4-day female    153 ovary, mated 4-day female    142 testis, mated 4-day male    30 accessory gland, mated 4-day male    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (102) central nervous system, larvae L3  (66) central nervous system, pupae P8  (50) head, virgin 1-day female  (155) head, virgin 4-day female  (91) head, virgin 20-day female  (171) head, mated 1-day female  (85) head, mated 4-day female  (72) head, mated 20-day female  (123) head, mated 1-day male  (182) head, mated 4-day male  (159) head, mated 20-day male  (206) salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering  (61) digestive system, 1-day adult  (158) digestive system, 4-day adult  (102) digestive system, 20-day adult  (135) fat body, larvae L3 wandering  (218) fat body, white prepupae    23 fat body, pupae P8  (71) carcass, larvae L3 wandering  (46) carcass, 1-day adult  (204) carcass, 4-day adult  (244) carcass, 20-day adult  (254) ovary, virgin 4-day female  (153) ovary, mated 4-day female  (142) testis, mated 4-day male  30 accessory gland, mated 4-day male  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  102 central nervous system, larvae L3    66 central nervous system, pupae P8    50 head, virgin 1-day female  (155) head, virgin 4-day female    91 head, virgin 20-day female  (171) head, mated 1-day female    85 head, mated 4-day female    72 head, mated 20-day female  123 head, mated 1-day male  (182) head, mated 4-day male  (159) head, mated 20-day male  (206) salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    61 digestive system, 1-day adult  (158) digestive system, 4-day adult  102 digestive system, 20-day adult  135 fat body, larvae L3 wandering  (218) fat body, white prepupae    23 fat body, pupae P8    71 carcass, larvae L3 wandering    46 carcass, 1-day adult  (204) carcass, 4-day adult  (244) carcass, 20-day adult  (254) ovary, virgin 4-day female  (153) ovary, mated 4-day female  142 testis, mated 4-day male    30 accessory gland, mated 4-day male    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    102 central nervous system, larvae L3    66 central nervous system, pupae P8    50 head, virgin 1-day female    155 head, virgin 4-day female    91 head, virgin 20-day female    171 head, mated 1-day female    85 head, mated 4-day female    72 head, mated 20-day female    123 head, mated 1-day male    182 head, mated 4-day male    159 head, mated 20-day male    206 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    61 digestive system, 1-day adult    158 digestive system, 4-day adult    102 digestive system, 20-day adult    135 fat body, larvae L3 wandering    218 fat body, white prepupae    23 fat body, pupae P8    71 carcass, larvae L3 wandering    46 carcass, 1-day adult    204 carcass, 4-day adult    244 carcass, 20-day adult    254 ovary, virgin 4-day female    153 ovary, mated 4-day female    142 testis, mated 4-day male    30 accessory gland, mated 4-day male    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    34 embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1    73 larva L2    181 larva L3 12hr old    151 larva L3 puffstage 1-2    146 larva L3 puffstage 3-6    36 larva L3 puffstage 7-9    33 white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP    35 pupae 3d postWPP    33 pupae 4d postWPP    35 adult male 01day    84 adult male 05day    115 adult male 30day    69 adult female 01day    58 adult female 05day    91 adult female 30day    90 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (68) embryo 02-04hr  (34) embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1  (73) larva L2  (181) larva L3 12hr old  (151) larva L3 puffstage 1-2  (146) larva L3 puffstage 3-6  (36) larva L3 puffstage 7-9  (33) white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP  (35) pupae 3d postWPP  (33) pupae 4d postWPP  (35) adult male 01day  (84) adult male 05day  (115) adult male 30day  (69) adult female 01day  (58) adult female 05day  (91) adult female 30day  (90) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    34 embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1    73 larva L2  (181) larva L3 12hr old  (151) larva L3 puffstage 1-2  (146) larva L3 puffstage 3-6    36 larva L3 puffstage 7-9    33 white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP    35 pupae 3d postWPP    33 pupae 4d postWPP    35 adult male 01day    84 adult male 05day  (115) adult male 30day    69 adult female 01day    58 adult female 05day    91 adult female 30day    90 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    34 embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1    73 larva L2    181 larva L3 12hr old    151 larva L3 puffstage 1-2    146 larva L3 puffstage 3-6    36 larva L3 puffstage 7-9    33 white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP    35 pupae 3d postWPP    33 pupae 4d postWPP    35 adult male 01day    84 adult male 05day    115 adult male 30day    69 adult female 01day    58 adult female 05day    91 adult female 30day    90 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    34 embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1    73 larva L2    181 larva L3 12hr old    151 larva L3 puffstage 1-2    146 larva L3 puffstage 3-6    36 larva L3 puffstage 7-9    33 white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP    35 pupae 3d postWPP    33 pupae 4d postWPP    35 adult male 01day    84 adult male 05day    115 adult male 30day    69 adult female 01day    58 adult female 05day    91 adult female 30day    90 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (68) embryo 02-04hr  (34) embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1  (73) larva L2  (181) larva L3 12hr old  (151) larva L3 puffstage 1-2  (146) larva L3 puffstage 3-6  (36) larva L3 puffstage 7-9  (33) white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP  (35) pupae 3d postWPP  (33) pupae 4d postWPP  (35) adult male 01day  (84) adult male 05day  (115) adult male 30day  (69) adult female 01day  (58) adult female 05day  (91) adult female 30day  (90) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    34 embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1    73 larva L2  (181) larva L3 12hr old  (151) larva L3 puffstage 1-2  (146) larva L3 puffstage 3-6    36 larva L3 puffstage 7-9    33 white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP    35 pupae 3d postWPP    33 pupae 4d postWPP    35 adult male 01day    84 adult male 05day  115 adult male 30day    69 adult female 01day    58 adult female 05day    91 adult female 30day    90 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    34 embryo 04-06hr    17 embryo 06-08hr    6 embryo 08-10hr    9 embryo 10-12hr    5 embryo 12-14hr    6 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    17 embryo 20-22hr    20 embryo 22-24hr    25 larva L1    73 larva L2    181 larva L3 12hr old    151 larva L3 puffstage 1-2    146 larva L3 puffstage 3-6    36 larva L3 puffstage 7-9    33 white prepupae new    18 white prepupae 12hr    25 white prepupae 24hr    20 pupae 2d postWPP    35 pupae 3d postWPP    33 pupae 4d postWPP    35 adult male 01day    84 adult male 05day    115 adult male 30day    69 adult female 01day    58 adult female 05day    91 adult female 30day    90 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    83 embryonic 1182-4H    87 embryonic GM2    169 embryonic Kc167    107 embryonic S1    46 embryonic S3    136 leg disc CME L1    63 wing disc CME-W2    72 wing disc ML-DmD8    170 wing disc ML-DmD9    197 wing disc ML-DmD16-c3    106 wing disc ML-DmD21    127 wing disc ML-DmD32    104 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    200 antennal disc ML-DmD20-c5    187 mixed discs ML-DmD4-c1    136 CNS ML-DmBG1-c1    106 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    180 ovary fGS/OSS    39 ovary OSC    33 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4  (83) embryonic 1182-4H  (87) embryonic GM2  (169) embryonic Kc167  (107) embryonic S1  (46) embryonic S3  (136) leg disc CME L1  (63) wing disc CME-W2  (72) wing disc ML-DmD8  (170) wing disc ML-DmD9  (197) wing disc ML-DmD16-c3  (106) wing disc ML-DmD21  (127) wing disc ML-DmD32  (104) haltere disc ML-DmD17-c3  (135) eye-antennal disc ML-DmD11  (200) antennal disc ML-DmD20-c5  (187) mixed discs ML-DmD4-c1  (136) CNS ML-DmBG1-c1  (106) CNS ML-DmBG2-c2  (56) tumorous blood cells mbn2  (180) ovary fGS/OSS  (39) ovary OSC  (33) ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    83 embryonic 1182-4H    87 embryonic GM2  (169) embryonic Kc167  107 embryonic S1    46 embryonic S3  (136) leg disc CME L1    63 wing disc CME-W2    72 wing disc ML-DmD8  (170) wing disc ML-DmD9  (197) wing disc ML-DmD16-c3  106 wing disc ML-DmD21  (127) wing disc ML-DmD32  104 haltere disc ML-DmD17-c3  (135) eye-antennal disc ML-DmD11  (200) antennal disc ML-DmD20-c5  (187) mixed discs ML-DmD4-c1  (136) CNS ML-DmBG1-c1  106 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2  (180) ovary fGS/OSS    39 ovary OSC    33 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    83 embryonic 1182-4H    87 embryonic GM2    169 embryonic Kc167    107 embryonic S1    46 embryonic S3    136 leg disc CME L1    63 wing disc CME-W2    72 wing disc ML-DmD8    170 wing disc ML-DmD9    197 wing disc ML-DmD16-c3    106 wing disc ML-DmD21    127 wing disc ML-DmD32    104 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    200 antennal disc ML-DmD20-c5    187 mixed discs ML-DmD4-c1    136 CNS ML-DmBG1-c1    106 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    180 ovary fGS/OSS    39 ovary OSC    33 ovary OSS    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    83 embryonic 1182-4H    87 embryonic GM2    169 embryonic Kc167    107 embryonic S1    46 embryonic S3    136 leg disc CME L1    63 wing disc CME-W2    72 wing disc ML-DmD8    170 wing disc ML-DmD9    197 wing disc ML-DmD16-c3    106 wing disc ML-DmD21    127 wing disc ML-DmD32    104 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    200 antennal disc ML-DmD20-c5    187 mixed discs ML-DmD4-c1    136 CNS ML-DmBG1-c1    106 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    180 ovary fGS/OSS    39 ovary OSC    33 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4  (83) embryonic 1182-4H  (87) embryonic GM2  (169) embryonic Kc167  (107) embryonic S1  (46) embryonic S3  (136) leg disc CME L1  (63) wing disc CME-W2  (72) wing disc ML-DmD8  (170) wing disc ML-DmD9  (197) wing disc ML-DmD16-c3  (106) wing disc ML-DmD21  (127) wing disc ML-DmD32  (104) haltere disc ML-DmD17-c3  (135) eye-antennal disc ML-DmD11  (200) antennal disc ML-DmD20-c5  (187) mixed discs ML-DmD4-c1  (136) CNS ML-DmBG1-c1  (106) CNS ML-DmBG2-c2  (56) tumorous blood cells mbn2  (180) ovary fGS/OSS  (39) ovary OSC  (33) ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    83 embryonic 1182-4H    87 embryonic GM2  (169) embryonic Kc167  107 embryonic S1    46 embryonic S3  136 leg disc CME L1    63 wing disc CME-W2    72 wing disc ML-DmD8  (170) wing disc ML-DmD9  (197) wing disc ML-DmD16-c3  106 wing disc ML-DmD21  127 wing disc ML-DmD32  104 haltere disc ML-DmD17-c3  135 eye-antennal disc ML-DmD11  (200) antennal disc ML-DmD20-c5  (187) mixed discs ML-DmD4-c1  136 CNS ML-DmBG1-c1  106 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2  (180) ovary fGS/OSS    39 ovary OSC    33 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    83 embryonic 1182-4H    87 embryonic GM2    169 embryonic Kc167    107 embryonic S1    46 embryonic S3    136 leg disc CME L1    63 wing disc CME-W2    72 wing disc ML-DmD8    170 wing disc ML-DmD9    197 wing disc ML-DmD16-c3    106 wing disc ML-DmD21    127 wing disc ML-DmD32    104 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    200 antennal disc ML-DmD20-c5    187 mixed discs ML-DmD4-c1    136 CNS ML-DmBG1-c1    106 CNS ML-DmBG2-c2    56 tumorous blood cells mbn2    180 ovary fGS/OSS    39 ovary OSC    33 ovary OSS    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    101 cold shock, 4-day adult    54 heat shock, 4-day adult    125 Cadmium 50 mM 6 hrs, larvae L3    178 Cadmium 50 mM 12 hrs, larvae L3    119 Cadmium 50 mM 48 hrs, 4-day adult    138 Cadmium 100 mM 48 hrs, 4-day adult    176 Copper 0.5 mM 12 hrs, larvae L3    128 Copper 15 mM 48 hrs, 4-day adult    31 Zinc 5 mM 12 hrs, larvae L3    109 Zinc 4.5 mM 48 hrs, 4-day adult    43 Ethanol 2.5% 3 hrs, larvae L3    176 Ethanol 5% 3 hrs, larvae L3    195 Ethanol 10% 3 hrs, larvae L3    182 Caffeine 1.5 mg/ml 4 hrs, larvae L3    242 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    177 Caffeine 25 mg/ml 48 hrs, 4-day adult    92 Paraquat 5 mM 48 hrs, 4-day adult    143 Paraquat 10 mM 48 hrs, 4-day adult    227 Rotenone 2 μg 12 hrs, larvae L3    202 Rotenone 8 μg 12 hrs, larvae L3    295 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (101) cold shock, 4-day adult  (54) heat shock, 4-day adult  (125) Cadmium 50 mM 6 hrs, larvae L3  (178) Cadmium 50 mM 12 hrs, larvae L3  (119) Cadmium 50 mM 48 hrs, 4-day adult  (138) Cadmium 100 mM 48 hrs, 4-day adult  (176) Copper 0.5 mM 12 hrs, larvae L3  (128) Copper 15 mM 48 hrs, 4-day adult  (31) Zinc 5 mM 12 hrs, larvae L3  (109) Zinc 4.5 mM 48 hrs, 4-day adult  (43) Ethanol 2.5% 3 hrs, larvae L3  (176) Ethanol 5% 3 hrs, larvae L3  (195) Ethanol 10% 3 hrs, larvae L3  (182) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (242) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (177) Caffeine 25 mg/ml 48 hrs, 4-day adult  (92) Paraquat 5 mM 48 hrs, 4-day adult  (143) Paraquat 10 mM 48 hrs, 4-day adult  (227) Rotenone 2 μg 12 hrs, larvae L3  (202) Rotenone 8 μg 12 hrs, larvae L3  (295) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  101 cold shock, 4-day adult    54 heat shock, 4-day adult  (125) Cadmium 50 mM 6 hrs, larvae L3  (178) Cadmium 50 mM 12 hrs, larvae L3  (119) Cadmium 50 mM 48 hrs, 4-day adult  (138) Cadmium 100 mM 48 hrs, 4-day adult  (176) Copper 0.5 mM 12 hrs, larvae L3  (128) Copper 15 mM 48 hrs, 4-day adult    31 Zinc 5 mM 12 hrs, larvae L3  (109) Zinc 4.5 mM 48 hrs, 4-day adult    43 Ethanol 2.5% 3 hrs, larvae L3  (176) Ethanol 5% 3 hrs, larvae L3  (195) Ethanol 10% 3 hrs, larvae L3  (182) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (242) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (177) Caffeine 25 mg/ml 48 hrs, 4-day adult    92 Paraquat 5 mM 48 hrs, 4-day adult  (143) Paraquat 10 mM 48 hrs, 4-day adult  (227) Rotenone 2 μg 12 hrs, larvae L3  (202) Rotenone 8 μg 12 hrs, larvae L3  (295) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    101 cold shock, 4-day adult    54 heat shock, 4-day adult    125 Cadmium 50 mM 6 hrs, larvae L3    178 Cadmium 50 mM 12 hrs, larvae L3    119 Cadmium 50 mM 48 hrs, 4-day adult    138 Cadmium 100 mM 48 hrs, 4-day adult    176 Copper 0.5 mM 12 hrs, larvae L3    128 Copper 15 mM 48 hrs, 4-day adult    31 Zinc 5 mM 12 hrs, larvae L3    109 Zinc 4.5 mM 48 hrs, 4-day adult    43 Ethanol 2.5% 3 hrs, larvae L3    176 Ethanol 5% 3 hrs, larvae L3    195 Ethanol 10% 3 hrs, larvae L3    182 Caffeine 1.5 mg/ml 4 hrs, larvae L3    242 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    177 Caffeine 25 mg/ml 48 hrs, 4-day adult    92 Paraquat 5 mM 48 hrs, 4-day adult    143 Paraquat 10 mM 48 hrs, 4-day adult    227 Rotenone 2 μg 12 hrs, larvae L3    202 Rotenone 8 μg 12 hrs, larvae L3    295 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    101 cold shock, 4-day adult    54 heat shock, 4-day adult    125 Cadmium 50 mM 6 hrs, larvae L3    178 Cadmium 50 mM 12 hrs, larvae L3    119 Cadmium 50 mM 48 hrs, 4-day adult    138 Cadmium 100 mM 48 hrs, 4-day adult    176 Copper 0.5 mM 12 hrs, larvae L3    128 Copper 15 mM 48 hrs, 4-day adult    31 Zinc 5 mM 12 hrs, larvae L3    109 Zinc 4.5 mM 48 hrs, 4-day adult    43 Ethanol 2.5% 3 hrs, larvae L3    176 Ethanol 5% 3 hrs, larvae L3    195 Ethanol 10% 3 hrs, larvae L3    182 Caffeine 1.5 mg/ml 4 hrs, larvae L3    242 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    177 Caffeine 25 mg/ml 48 hrs, 4-day adult    92 Paraquat 5 mM 48 hrs, 4-day adult    143 Paraquat 10 mM 48 hrs, 4-day adult    227 Rotenone 2 μg 12 hrs, larvae L3    202 Rotenone 8 μg 12 hrs, larvae L3    295 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (101) cold shock, 4-day adult  (54) heat shock, 4-day adult  (125) Cadmium 50 mM 6 hrs, larvae L3  (178) Cadmium 50 mM 12 hrs, larvae L3  (119) Cadmium 50 mM 48 hrs, 4-day adult  (138) Cadmium 100 mM 48 hrs, 4-day adult  (176) Copper 0.5 mM 12 hrs, larvae L3  (128) Copper 15 mM 48 hrs, 4-day adult  31 Zinc 5 mM 12 hrs, larvae L3  (109) Zinc 4.5 mM 48 hrs, 4-day adult  (43) Ethanol 2.5% 3 hrs, larvae L3  (176) Ethanol 5% 3 hrs, larvae L3  (195) Ethanol 10% 3 hrs, larvae L3  (182) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (242) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (177) Caffeine 25 mg/ml 48 hrs, 4-day adult  (92) Paraquat 5 mM 48 hrs, 4-day adult  (143) Paraquat 10 mM 48 hrs, 4-day adult  (227) Rotenone 2 μg 12 hrs, larvae L3  (202) Rotenone 8 μg 12 hrs, larvae L3  (295) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  101 cold shock, 4-day adult    54 heat shock, 4-day adult  125 Cadmium 50 mM 6 hrs, larvae L3  (178) Cadmium 50 mM 12 hrs, larvae L3  119 Cadmium 50 mM 48 hrs, 4-day adult  138 Cadmium 100 mM 48 hrs, 4-day adult  (176) Copper 0.5 mM 12 hrs, larvae L3  128 Copper 15 mM 48 hrs, 4-day adult    31 Zinc 5 mM 12 hrs, larvae L3  109 Zinc 4.5 mM 48 hrs, 4-day adult    43 Ethanol 2.5% 3 hrs, larvae L3  (176) Ethanol 5% 3 hrs, larvae L3  (195) Ethanol 10% 3 hrs, larvae L3  (182) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (242) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (177) Caffeine 25 mg/ml 48 hrs, 4-day adult    92 Paraquat 5 mM 48 hrs, 4-day adult  143 Paraquat 10 mM 48 hrs, 4-day adult  (227) Rotenone 2 μg 12 hrs, larvae L3  (202) Rotenone 8 μg 12 hrs, larvae L3  (295) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    101 cold shock, 4-day adult    54 heat shock, 4-day adult    125 Cadmium 50 mM 6 hrs, larvae L3    178 Cadmium 50 mM 12 hrs, larvae L3    119 Cadmium 50 mM 48 hrs, 4-day adult    138 Cadmium 100 mM 48 hrs, 4-day adult    176 Copper 0.5 mM 12 hrs, larvae L3    128 Copper 15 mM 48 hrs, 4-day adult    31 Zinc 5 mM 12 hrs, larvae L3    109 Zinc 4.5 mM 48 hrs, 4-day adult    43 Ethanol 2.5% 3 hrs, larvae L3    176 Ethanol 5% 3 hrs, larvae L3    195 Ethanol 10% 3 hrs, larvae L3    182 Caffeine 1.5 mg/ml 4 hrs, larvae L3    242 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    177 Caffeine 25 mg/ml 48 hrs, 4-day adult    92 Paraquat 5 mM 48 hrs, 4-day adult    143 Paraquat 10 mM 48 hrs, 4-day adult    227 Rotenone 2 μg 12 hrs, larvae L3    202 Rotenone 8 μg 12 hrs, larvae L3    295 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • RH59553 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025814 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1742-RB;CG1742-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Mgstl Stages(s) 1-3 Stages(s) 4-6 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die, with Scer\GAL429BD MgstlGS1051 partially lethal - majority die, with Scer\GAL4c355 MgstlGS1051 partially lethal - majority die, with Scer\GAL4dpp.blk1 MgstlGS1051 partially lethal - majority die, with Scer\GAL4hs.2sev MgstlGS1051 viable MgstlE8 MgstlE41 MgstlE54 MgstlE65 Sterility Allele fertile MgstlE8 MgstlE41 MgstlE54 MgstlE65 Other Phenotypes Allele short lived (with Df(1)16-3-22) MgstlE54 MgstlE65 short lived (with Df(1)mal3) MgstlE54 MgstlE65 visible, with Scer\GAL429BD MgstlGS1051 visible, with Scer\GAL4c355 MgstlGS1051 visible, with Scer\GAL4dpp.blk1 MgstlGS1051 visible, with Scer\GAL4hs.2sev MgstlGS1051 Phenotype manifest in Allele arista, with Scer\GAL429BD MgstlGS1051 arista, with Scer\GAL4c355 MgstlGS1051 arista, with Scer\GAL4dpp.blk1 MgstlGS1051 eye, with Scer\GAL429BD MgstlGS1051 eye, with Scer\GAL4c355 MgstlGS1051 eye, with Scer\GAL4dpp.blk1 MgstlGS1051 eye, with Scer\GAL4hs.2sev MgstlGS1051 macrochaeta, with Scer\GAL429BD MgstlGS1051 macrochaeta, with Scer\GAL4c355 MgstlGS1051 macrochaeta, with Scer\GAL4dpp.blk1 MgstlGS1051 scutellum, with Scer\GAL429BD MgstlGS1051 scutellum, with Scer\GAL4c355 MgstlGS1051 scutellum, with Scer\GAL4dpp.blk1 MgstlGS1051 tarsal segment, with Scer\GAL429BD MgstlGS1051 tarsal segment, with Scer\GAL4c355 MgstlGS1051 tarsal segment, with Scer\GAL4dpp.blk1 MgstlGS1051 wing, with Scer\GAL429BD MgstlGS1051 wing, with Scer\GAL4c355 MgstlGS1051 wing, with Scer\GAL4dpp.blk1 MgstlGS1051
Classical Alleles ( 17 )
For All Classical Alleles Show
Allele of Mgstl Class Mutagen Stocks Known lesion Mgstld10243 P-element activity 1 -- MgstlG2080 P-element activity 1 -- MgstlGS1051 Delta2-3 1 Yes MgstlKG04713 1 -- MgstlNP2323 1 -- MgstlNP3209 1 -- MgstlNP4038 1 -- MgstlNP4067 1 -- MgstlNP5025 1 -- Mgstld01365 0 -- Mgstld01627 0 -- MgstlE41 Delta2-3 0 Yes MgstlE54 Delta2-3 0 Yes MgstlE65 Delta2-3 0 Yes MgstlE8 Delta2-3 0 Yes MgstlEP1530 0 -- MgstlGG01630 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Mgstl Class Mutagen Stocks Known lesion MgstlKK115865 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes MgstlNIG.1742R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)16-3-22 (Toba and Aigaki, 2000) Df(1)mal3 (Toba and Aigaki, 2000)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3700} NA P{GD17449} NA P{GD17608} NA P{KK115865} NA P{NIG.1742R} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system P{GawB}MgstlNP2323 No P{GawB}MgstlNP3209 No P{GawB}MgstlNP4038 No P{GawB}MgstlNP4067 No P{GawB}MgstlNP5025 No miscellaneous insertions P{SUPor-P}MgstlKG04713 NA insertion of mobile activating element P{EP}MgstlEP1530 NA P{EP}MgstlG2080 NA P{GSV1}MgstlGS1051 NA P{Mae-UAS.6.11}MgstlGG01630 NA P{XP}Mgstld01365 NA P{XP}Mgstld01627 NA P{XP}Mgstld10243 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
glutathione transferase activity inferred from sequence or structural similarity (Toba, 1998.12.4, Toba, 1998.12.4) inferred from sequence or structural similarity with human MGST1 (Toba et al., 1999) inferred from sequence or structural similarity with UniProtKB:P10620 (Sardiello et al., 2003.6.11)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
intracellular membrane-bounded organelle inferred from sequence or structural similarity with human MGST1 (Toba et al., 1999) inferred from sequence or structural similarity with UniProtKB:P10620 (Sardiello et al., 2003.6.11) mitochondrial outer membrane inferred from sequence or structural similarity with UniProtKB:P10620 (Sardiello et al., 2003.6.11)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Mgstl - Arp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - Arpc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - Arpc5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - CG10641 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - CG1129 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - CG15098 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - CG9547 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - Cyp9f2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - REG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - Snap anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - Trap1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - Tsp29Fb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Mgstl - cpb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Mgstl allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0025814 DroID - A comprehensive database of gene and protein interactions. • FBgn0025814 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44110
Orthologs
OrthoDB Orthologs (58) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69S6ST Dipteran inclusive ortholog search EOG6DJK5P Insect inclusive ortholog search EOG637QBP Arthropod inclusive ortholog search EOG65MKP2 Metazoa inclusive ortholog search EOG6VF2TT
Orthologs in Drosophila Species (EOG69S6ST)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Mgstl     Drosophila simulans   Dsim\GD17510 Y   Drosophila sechellia   Dsec\GM23058 Y   Drosophila erecta   Dere\GG19704 Y   Drosophila yakuba   Dyak\GE17903 Y   Drosophila ananassae   Dana\GF21709 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA14506 Y   Drosophila persimilis   Dper\GL16397 Y   Drosophila willistoni   Dwil\GK25033 Y   Drosophila virilis   Dvir\GJ18600 Y   Drosophila mojavensis   Dmoj\GI15739 Y   Drosophila grimshawi   Dgri\GH12207 Y
Orthologs in non-Drosophila Dipterans (EOG6DJK5P)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006829   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010157   Anopheles gambiae Malaria mosquito  Agam\GSTmic2   Anopheles gambiae Malaria mosquito  Agam\GSTmic1   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ012756   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015233   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ018241
Orthologs in non-Dipteran Insects (EOG637QBP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GST-mic1 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG020476 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22697 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO15502 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14223 Y Linepithema humile Argentine ant  Lhum\LH21626 Y Solenopsis invicta Red fire ant  Sinv\SINV18912 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI004835 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI006691 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007779 Y Pediculus humanus Human body louse  Phum\PHUM361810 Y Pediculus humanus Human body louse  Phum\PHUM080470 Y Tribolium castaneum Red flour beetle  Tcas\TC009129 Y Tribolium castaneum Red flour beetle  Tcas\TC009128 Y Tribolium castaneum Red flour beetle  Tcas\TC011646 Y
Orthologs in non-Insect Arthropods (EOG65MKP2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\amyA Y Daphnia pulex Water flea  Dpux\tam Y
Orthologs in non-Arthropod Metazoa (EOG6VF2TT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026328gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007735gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026329gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026325gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009414gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028086gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028087gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026330gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007777gn Y Danio rerio Zebrafish  Drer\mgst1 Y Danio rerio Zebrafish  Drer\DKEY-8M7.1 Y Danio rerio Zebrafish  Drer\ptges Y Xenopus tropicalis Western clawed frog  Xtro\ptges Y Xenopus tropicalis Western clawed frog  Xtro\mgst1 Y Gallus gallus Domestic chicken  Ggal\PTGES Y Gallus gallus Domestic chicken  Ggal\MGST1 Y Mus musculus House mouse  Mmus\Mgst1 Y Mus musculus House mouse  Mmus\Ptges Y Rattus norvegicus Norway rat  Rnor\Ptges Y Rattus norvegicus Norway rat  Rnor\Mgst1 Y Homo sapiens Human  Hsap\PTGES Y Homo sapiens Human  Hsap\MGST1 Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\PTGES     Hsap\MGST1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17510 Drosophila sechellia Dsec\GM23058 Drosophila erecta Dere\GG19704 Drosophila yakuba Dyak\GE17903 Drosophila ananassae Dana\GF21709 Drosophila pseudoobscura pseudoobscura Dpse\GA14506 Drosophila persimilis Dper\GL16397 Drosophila willistoni Dwil\GK25033 Drosophila virilis Dvir\GJ18600 Drosophila mojavensis Dmoj\GI15739 Drosophila grimshawi Dgri\GH12207
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	28431 w* P{EP}MgstlG2080 13839 y1 P{SUPor-P}MgstlKG04713
Harvard	- P{XP}Mgstld10243
Kyoto	112882 w* P{GawB}MgstlNP2323 / FM7c 113158 w* P{GawB}MgstlNP3209 / FM7c 113388 w* P{GawB}MgstlNP4038 / FM7c 113393 w* P{GawB}MgstlNP4067 / FM7c 104810 y* w* P{GawB}MgstlNP5025 / FM7c 205029 y1 w67c23 P{GSV1}MgstlGS1051/Binsinscy
Genomic Clones ( 1 )
	BACR35D19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 58 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH08455 IP16068 RE10696 RH59553 RH74014
Other clones	DPiM_RE10696 IP16368
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH17375 GH21436 GH21443 GH24879 LP12215 RE11045 RE29476 RE41757 RH22926 RH23682 RH25666 RH28203 RH31028 RH34075 RH39674 RH41972 RH42072 RH46964 RH47064 RH48965 RH49534 RH61914 RH62586 RH63337 RH69306
Other clones	31358 524072 CK01.23B.F10 Dmel_dig_008053_0599_1852 Dmel_neb_011768_0340_2452 Dmel_neb_015095_0913_0517 EC00535 EC01535 EC43733 EK139914 EN03907 EN04717 FGM228B07 IP05723 IP09601 IP16168 IP16268 RP004228325 RP004247924 RP004261547 RP004270074 RP004459678 RP004470983 RP004524445 RP004547460 UUGC0892
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0025814 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44110
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Mgstl CG1742 (Li, 1999.11)
Source for database merge of	Source for merge of: Mgstl BcDNA:RE10696 (FlyBase, 1996-) Source for merge of: Mgstl BcDNA:RH59553 (FlyBase, 1996-) Source for merge of: Mgstl CG1742 (Bayraktaroglu, 2000.4.17)
Additional comments	The Mgstl-Ψ gene may be derived from the Mgstl gene by retroposition. (Betran et al., 2002) Source for merge of Mgstl BcDNA:RE10696 was a shared cDNA (date:030728). (FlyBase, 1996-) Source for merge of Mgstl BcDNA:RH59553 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079957 NM_167724 RefSeq (Proteins) • NP_524696 NP_728382 DDBJ / EMBL / GenBank • AAC98692 AAC98694 AAF50864 AAL49374 AAL68265 AAN09527 AF111426 AF111428 AY071752 AY075452 BI169509 BI630498 CZ477173 Entrez Gene - A searchable database of RefSeq genes. • 44110 UniProtKB/TrEMBL • O97471 Q8SY19 Q8SY70
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein (IPR001129) Membrane associated eicosanoid/glutathione metabolism-like domain (IPR023352) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME01742 BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RH59553
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0025814 DroID - A comprehensive database of gene and protein interactions. • FBgn0025814 DRSC - Results from RNAi screens. • FBgn0025814 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025814 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1742-RB;CG1742-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0025814 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44110 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44110 modMine - Data generated by the modENCODE project. • FBgn0025814
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BcDNA:RE10696   BcDNA:RH59553   CG1742 (Roxstrom-Lindquist et al., 2004, Zhan et al., 2011, Keleman et al., 2009.8.5, Cammarato et al., 2011) Mgst1 (Betran et al., 2002, Barnes et al., 2010, Bresell et al., 2005) Mgstl (Beller et al., 2006, Langille and Clark, 2007, Butchar et al., 2012, Li et al., 2008, Japanese National Institute of Genetics, 2012.5.21, Gurudatta et al., 2012)
Name Synonym	microsomal glutathione (Bresell et al., 2005) Microsomal glutathione S-transferase-like (Lebo et al., 2009, Cammarato et al., 2011) microsomal glutathione transferase 1 (Barnes et al., 2010) transferase (Bresell et al., 2005)
Secondary FlyBase IDs
	FBgn0031147 FBgn0047002 FBgn0061409
References ( 36 )
Generate a list of	All references relating to this gene ( 36 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) Curated genome annotation  ( 3 ) DNA/RNA sequence record  ( 2 ) Website  ( 1 )
Recent research papers ( 3 )
	Butchar et al., 2012, Genetics 191(4): 1213--1226 New negative feedback regulators of egfr signaling in Drosophila. [FBrf0219175] Gurudatta et al., 2012, Dev. Biol. 369(1): 124--132 The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. [FBrf0219796] Zhan et al., 2011, Gene 470(1-2): 1--6 Evolution of alternative splicing in newly evolved genes of Drosophila. [FBrf0212278] Show all research papers ...