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Gene Dmel\JTBR

General Information
Symbol	Dmel\JTBR	Species	D. melanogaster
Name	JTBR	Annotation symbol	CG1935
Feature type	protein_coding_gene	FlyBase ID	FBgn0025820
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	62B4-62B4	Sequence location	3L:1,802,008..1,802,856 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene JTBR is referred to in FlyBase by the symbol Dmel\JTBR (CG1935, FBgn0025820). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Jumping translocation breakpoint. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632954_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of JTBR. Gene sequence location is 3L:1802008..1802856.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 62B4-62B4   Limits computationally determined from genome sequence between P{PZ}dlt04276 and P{PZ}slsrL182
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\JTBR for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) JTBR-RA FBtr0072788  NM_058055   849   152 JTBR-RB FBtr0332876  NM_001274360   789   152 JTBR-RC FBtr0332877  NM_001274361   799   152
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein JTBR-PA   FBpp0072671   17.9   152   8.21     NP_477403   AAF47574 JTBR-PB   FBpp0305098   17.9   152   8.21     NP_001261289   AGB93984 JTBR-PC   FBpp0305099   17.9   152   8.21     NP_001261290   AGB93985
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Jumping translocation breakpoint (IPR008657)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA433267   AE014296 AAF47574   AB016494 BAA34304   AC005557   AE014296 AGB93984   AE014296 AGB93985   AY084195 AAL89933   BI572461   BP547090   BT032659   CO187307   CO308182   EC089074   EC089078   EC212094   EC217879   EC226555   EV580563   GH943290   GH947482   GH949217   GH949646   GH951100   GH951408   GH954343   GH954536   GH955410   GH955652   GH956704   GH957297   GH957446   GH959564   GH960734   GH966953   GH968182   GH968262   GH968425   GH968590   GH971077   GH971602   GH974268   GH975522   GH978402   GH980463   GH982069   GH983071   GH983880   GH984210
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O96067 Q8SXQ3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval salivary gland, larval trachea, adult ovary, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    128.65 Larval Midgut    79.8 Larval Hindgut    114.3 Larval Malpighian Tubules    106.5 Larval Fat Body    121.8 Larval Salivary Gland    106.7 Larval Trachea    221.9 Larval Carcass    113.75 Adult Head    110.7 Adult Eye    168.175 Adult Brain    135.4 Adult Thoracic-Abdominal Ganglion    136.6 Adult Crop    158.6 Adult Midgut    123.3 Adult Hindgut    160.7 Adult Malpighian Tubules    74.6 Adult Fat Body    94.7 Adult Salivary Gland    77.3 Adult Heart    150.9 Adult VirginFemale Spermatheca    72.1 Adult InseminatedFemale Spermatheca    97.4 Adult Ovary    170.9 Adult Testis    85.7 Adult Male Accessory Gland    90.8 Adult Carcass    108.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    110.7   NA  Eye    168.175   NA  Brain    135.4   128.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    136.6   NA  Crop    158.6   79.8  Midgut    123.3   114.3  Hindgut    160.7   106.5  Malpighian Tubules    no informative data   121.8  Fat Body    94.7   106.7  Salivary Gland    no informative data   NA  Heart    150.9   221.9  Trachea    NA   NA  VirginFemale Spermatheca    72.1   NA  InseminatedFemale Spermatheca    97.4   NA  Ovary    170.9   NA  Testis    85.7   NA  Male Accessory Gland    90.8   113.75  Carcass    108.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    12 central nervous system, larvae L3    6 central nervous system, pupae P8    6 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    3 head, mated 1-day female    4 head, mated 4-day female    4 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    6 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    7 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    8 carcass, larvae L3 wandering    7 carcass, 1-day adult    4 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    16 ovary, mated 4-day female    14 testis, mated 4-day male    12 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr    28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (45) embryo 02-04hr  (30) embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr  (28) embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day  (29) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr    28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr    28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day    29 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr    28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (45) embryo 02-04hr  30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr  28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day  29 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr    28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    30 embryo 04-06hr    18 embryo 06-08hr    22 embryo 08-10hr    23 embryo 10-12hr    28 embryo 12-14hr    16 embryo 14-16hr    16 embryo 16-18hr    13 embryo 18-20hr    12 embryo 20-22hr    12 embryo 22-24hr    14 larva L1    14 larva L2    13 larva L3 12hr old    12 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    23 pupae 3d postWPP    15 pupae 4d postWPP    13 adult male 01day    14 adult male 05day    17 adult male 30day    19 adult female 01day    20 adult female 05day    25 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1    32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    36 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1  (32) embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9  (27) wing disc ML-DmD16-c3    15 wing disc ML-DmD21  26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5  (36) mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1    32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    36 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1    32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    36 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1    32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    36 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1  32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9  27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21  26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5  (36) mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1    32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    36 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    19 embryonic 1182-4H    11 embryonic GM2    15 embryonic Kc167    19 embryonic S1    32 embryonic S3    11 leg disc CME L1    17 wing disc CME-W2    17 wing disc ML-DmD8    22 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    26 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    36 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    20 ovary fGS/OSS    16 ovary OSC    15 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    10 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    13 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    18 Ethanol 5% 3 hrs, larvae L3    8 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    8 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    13 Rotenone 2 μg 12 hrs, larvae L3    9 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • RH07980 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025820 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1935-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of JTBR Class Mutagen Stocks Known lesion JTBRG4076 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of JTBR Class Mutagen Stocks Known lesion JTBRGD439 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes JTBRKK110496 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes JTBRNIG.1935R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6088 (Ryder, 2004.4.26) Df(3L)MY10 (Nam and Choi, 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD439} NA P{KK110496} NA P{NIG.1935R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}JTBRG4076 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR008657 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions JTBR allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0025820
Orthologs
OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6WDDZD Dipteran inclusive ortholog search EOG6ZCTDX Insect inclusive ortholog search EOG6BRVHD Arthropod inclusive ortholog search EOG6QJQ4W Metazoa inclusive ortholog search EOG66B3Q5
Orthologs in Drosophila Species (EOG6WDDZD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\JTBR     Drosophila simulans   Dsim\GD13436 Y   Drosophila sechellia   Dsec\GM14167 Y   Drosophila erecta   Dere\GG14558 Y   Drosophila yakuba   Dyak\GE20912 Y   Drosophila ananassae   Dana\GF24960 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA15138 Y   Drosophila persimilis   Dper\GL24826 Y   Drosophila persimilis   Dper\GL15613     Drosophila willistoni   Dwil\GK20566 Y   Drosophila virilis   Dvir\GJ12948 Y   Drosophila mojavensis   Dmoj\GI12800 Y   Drosophila grimshawi   Dgri\GH15043 Y
Orthologs in non-Drosophila Dipterans (EOG6ZCTDX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007026   Anopheles gambiae Malaria mosquito  Agam\AGAP008669   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001575
Orthologs in non-Dipteran Insects (EOG6BRVHD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB55588   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG020480   Atta cephalotes Leafcutter ant  Acep\ACEP20203   Camponotus floridanus Florida carpenter ant  Cflo\CFLO21703   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16424   Linepithema humile Argentine ant  Lhum\LH18596   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12359   Solenopsis invicta Red fire ant  Sinv\SINV26027   Acyrthosiphon pisum Pea aphid  Apim\ACYPI000118   Bombyx mori Silkmoth  Bmor\BGIBMGA011621   Pediculus humanus Human body louse  Phum\PHUM037820   Tribolium castaneum Red flour beetle  Tcas\TC009835
Orthologs in non-Insect Arthropods (EOG6QJQ4W)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\atp1   Ixodes scapularis Deer tick  Isca\ISCW016151
Orthologs in non-Arthropod Metazoa (EOG66B3Q5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\jtr-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025000gn   Danio rerio Zebrafish  Drer\si:ch211-191i18.1   Mus musculus House mouse  Mmus\Jtb   Rattus norvegicus Norway rat  Rnor\Jtb   Homo sapiens Human  Hsap\JTB
Human Orthologs (1)
Gene OMIM HGNC Hsap\JTB
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13436 Drosophila sechellia Dsec\GM14167 Drosophila erecta Dere\GG14558 Drosophila yakuba Dyak\GE20912 Drosophila ananassae Dana\GF24960 Drosophila pseudoobscura pseudoobscura Dpse\GA15138 Drosophila persimilis Dper\GL24826 Drosophila willistoni Dwil\GK20566 Drosophila virilis Dvir\GJ12948 Drosophila mojavensis Dmoj\GI12800 Drosophila grimshawi Dgri\GH15043
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	27144 y1 w*; P{EP}JTBRG4076
VDRC	v107405 P{KK110496}VIE-260B v51054 w1118; P{GD439}v51054 v51055 w1118; P{GD439}v51055 v52670 w1118; P{GD439}v52670
Genomic Clones ( 1 )
	BACR10D15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 42 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH07980
Other clones	FI02974
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	65453 153449 153517 153583 AA433267 CK01.32C.B2 Dmel_dig_012842_0675_0741 EK027937 EK256930 FGH113C11 RP004059155 RP004062133 RP004073084 RP004093369 RP004097954 RP004112777 RP004115505 RP004164850 RP004166724 RP004180489 RP004187330 RP004200600 RP004205082 RP004208461 RP004214774 RP004225584 RP004241334 RP004251443 RP004260302 RP004340663 RP004366963 RP004409822 RP004418066 RP004453428 RP004455844 RP004457771 RP004458969 RP004473850 RP004542276 RP004556790
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0025820 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38235
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: JTBR CG1935 (Deng, 1999.11)
Source for database merge of	Source for merge of: CG1935 anon-EST:fe2G4 (Bayraktaroglu, 2000.11.2) Source for merge of: JTBR BcDNA:RH07980 (FlyBase, 1996-) Source for merge of: JTBR CG1935 (Bayraktaroglu, 2000.4.17)
Additional comments	Source for merge of JTBR BcDNA:RH07980 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_058055 NM_001274360 NM_001274361 RefSeq (Proteins) • NP_477403 NP_001261289 NP_001261290 DDBJ / EMBL / GenBank • AA433267 AAF47574 AAL89933 AB016494 AC005557 AGB93984 AGB93985 AY084195 BAA34304 BI572461 Entrez Gene - A searchable database of RefSeq genes. • 38235 UniProtKB/TrEMBL • O96067 Q8SXQ3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Jumping translocation breakpoint (IPR008657) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RH07980
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0025820 DRSC - Results from RNAi screens. • FBgn0025820 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0025820 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1935-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0025820 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38235 modMine - Data generated by the modENCODE project. • FBgn0025820
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	anon-EST:fe2G4   BcDNA:RH07980   CG1935 (Sierralta, 2000.4.28, Keleman et al., 2009.8.5) dJTB-like   dJTBR (Hatakeyama, 1998.7.22, ) JTBR (Nam and Choi, 2006, Japanese National Institute of Genetics, 2012.5.21) unnamed (Schmid and Tautz, 1997)
Name Synonym	anon-fast-evolving-2G4   JTBR   Jumping Translocation Breakpoint (Nam and Choi, 2006)
Secondary FlyBase IDs
	FBgn0025210 FBgn0035275 FBgn0063663
References ( 20 )
Research paper	Nam and Choi, 2006, Dev. Dyn. 235(6): 1501--1507 Domain-specific early and late function of Dpatj in Drosophila photoreceptor cells. [FBrf0190243] Schmid and Tautz, 1997, Proc. Natl. Acad. Sci. U.S.A. 94(18): 9746--9750 A screen for fast evolving genes from Drosophila. [FBrf0098343]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979]
Erratum	Bhat et al., 2003, Cell 115(6): 765--766 Erratum. Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity. [FBrf0173209]
Personal communication to FlyBase	Bellen, 2009.4.8, BDGP_2009_0408.GenExel.xml BDGP_2009_0408.GenExel.xml [FBrf0207636] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Bayraktaroglu, 2000.4.17, Annotation identities: Category 8. Annotation identities: Category 8. [FBrf0126923] Bayraktaroglu, 2000.11.2, Current list of possibly CG-able known genes. Current list of possibly CG-able known genes. [FBrf0131225] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] Sierralta, 2000.4.28, FlyBase error report for CG12021 on Fri Apr 28 08:47:16 2000. FlyBase error report for CG12021 on Fri Apr 28 08:47:16 2000. [FBrf0129013]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
DNA/RNA sequence record	Hatakeyama, 1998.7.22, GenBank/EMBL/DDBJ: AB016494 Drosophila melanogaster dJTBR mRNA, complete cds. [FBrf0115909]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Curated genome annotation	Deng, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0128757]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]