APP, Aβ, Aβ42, AβPP, amyloid precursor protein
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Hsap\APP using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Hsap\APP in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
FlyBase curator comment: Name changed to reflect current HGNC name (19th Nov. 2012).
Expression of Hsap\APP in Drosophila induces AICD-dependent cell death and a locomotion defect.
Expression of Hsap\APP is able to induce cell death in non-neuronal tissues during development.