dek, Deph, lincRNA.923, CT3831, Eph receptor
receptor tyrosine kinase involved in axon pathfinding - functions in shaping of the wing compartment boundary
Please see the JBrowse view of Dmel\Eph for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Alternative translation stop created by use of multiphasic reading frames within coding region.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Eph using the Feature Mapper tool.
Comment: higher concentration at posterior pole
Eph protein is expressed uniformly in the eye disc, posterior to the morphogenetic furrow. In the lamina, expression is highest at the posterior midline, and lowest at the dorsal-ventral margins of the anterior midline. Within the medulla, expression of Eph protein is the highest at the midline, decreasing along the dorsal-ventral axis.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Eph in GBrowse 24-0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: Eph CG1511
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identification: PCR screen using degenerate primers to conserved regions within the kinase domain of RTKs.
Identification: recovered from a PCR-based screen for receptor tyrosine kinase encoding genes.
Dek7 is given as a temporary designation.
