FB2020_06, released Dec 22, 2020

Gene: Dmel\Nsun2

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General Information
Symbol
Dmel\Nsun2
Species
D. melanogaster
Name
NOP2-Sun domain family, member 2
Annotation Symbol
CG6133
Feature Type
protein_coding_gene
FlyBase ID
FBgn0026079
Gene Model Status
Current
Stock Availability
3 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Key Links
Genomic Location
Cytogenetic map
4A5-4A6
Sequence location
X:4,111,156..4,113,734 [-]
Recombination map

1-6

RefSeq locus
NC_004354 REGION:4111156..4113734
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (10 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables RNA binding
inferred from mutant phenotype
(Genenncher et al., 2018)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables methyltransferase activity
inferred from biological aspect of ancestor with PANTHER:PTN000516075
(assigned by GO_Central )
(Gaudet et al., 2011)
enables tRNA (cytosine-5-)-methyltransferase activity
inferred from sequence or structural similarity with HGNC:25994
(Abbasi-Moheb et al., 2012)
inferred from sequence or structural similarity with UniProtKB:Q08J23
(assigned by UniProt )
(UniProt Curators, 2002-)
inferred from biological aspect of ancestor with PANTHER:PTN000516077
(assigned by GO_Central )
(Gaudet et al., 2011)
enables tRNA binding
inferred from biological aspect of ancestor with PANTHER:PTN000516077
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in short-term memory
inferred from mutant phenotype
(Abbasi-Moheb et al., 2012)
involved_in tRNA methylation
inferred from mutant phenotype
(Genenncher et al., 2018)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in RNA methylation
inferred from sequence or structural similarity with HGNC:25994
(Abbasi-Moheb et al., 2012)
inferred from biological aspect of ancestor with PANTHER:PTN000516075
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in tRNA methylation
inferred from sequence or structural similarity with UniProtKB:Q08J23
(assigned by UniProt )
(UniProt Curators, 2002-)
inferred from biological aspect of ancestor with PANTHER:PTN000516077
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Gerbasi et al., 2011)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from sequence or structural similarity with UniProtKB:Q08J23
(assigned by UniProt )
(UniProt Curators, 2002-)
inferred from biological aspect of ancestor with PANTHER:PTN000516077
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in nucleolus
inferred from sequence or structural similarity with UniProtKB:Q08J23
(assigned by UniProt )
(UniProt Curators, 2002-)
located_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN000516077
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. TRM4 subfamily. (Q9W4M9)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
TRNA METHYLTRANSFERASES -
tRNA methyltransferases catalyze the transfer of methyl group from methyl donor to a nucleoside residue in an tRNA molecule.
Protein Function (UniProtKB)
RNA methyltransferase that methylates tRNAs. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Required for short-term memory.
(UniProt, Q9W4M9)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Nsun2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Nsun2-RA
FBtr0070669
NM_143750
2444
746
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Nsun2-PA
FBpp0070637
84.2
746
6.82
NP_652007
AAF45921
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Nsun2 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 12 -- 17
embryonic/larval proventriculus
(Abbasi-Moheb et al., 2012)
embryonic/larval hindgut
(Abbasi-Moheb et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Abbasi-Moheb et al., 2012)
Additional Descriptive Data

Nsun2 is expressed throughout the embryo with enrichment in the proventriculus and hindgut.

(Abbasi-Moheb et al., 2012)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
day 5 of adulthood & male -- day 7 of adulthood & male
spermatozoon
(Wasbrough et al., 2010)
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Gerbasi et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Nsun2 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 4 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Nsun2
Transgenic constructs containing regulatory region of Nsun2
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
female semi-fertile
male fertile
Other Phenotypes
Allele
memory defective
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (7)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\NSUN2
14 of 15
Yes
Yes
Hsap\NOP2
1 of 15
No
No
Hsap\NSUN3
1 of 15
No
No
Hsap\NSUN4
1 of 15
No
No
Hsap\NSUN5
1 of 15
No
No
Hsap\NSUN6
1 of 15
No
No
Hsap\NSUN7
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (7)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Nsun2
12 of 15
Yes
Yes
Mmus\Nop2
1 of 15
No
No
Mmus\Nsun3
1 of 15
No
No
Mmus\Nsun4
1 of 15
No
No
Mmus\Nsun5
1 of 15
No
No
Mmus\Nsun6
1 of 15
No
No
Mmus\Nsun7
1 of 15
No
No
Rattus norvegicus (Norway rat) (7)
Rnor\Nsun2
13 of 13
Yes
Yes
Rnor\LOC103690007
1 of 13
No
No
Rnor\Nop2
1 of 13
No
No
Rnor\Nsun4
1 of 13
No
No
Rnor\Nsun5
1 of 13
No
No
Rnor\Nsun6
1 of 13
No
No
Rnor\Nsun7
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (7)
Xtro\nsun2
13 of 12
Yes
Yes
Xtro\nop2
1 of 12
No
No
Xtro\nsun3
1 of 12
No
No
Xtro\nsun4
1 of 12
No
No
Xtro\nsun5
1 of 12
No
No
Xtro\nsun6
1 of 12
No
No
Xtro\nsun7
1 of 12
No
No
Danio rerio (Zebrafish) (6)
Drer\nsun2
14 of 15
Yes
Yes
Drer\nop2
1 of 15
No
No
Drer\nsun3
1 of 15
No
No
Drer\nsun4
1 of 15
No
No
Drer\nsun5
1 of 15
No
No
Drer\nsun6
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (4)
Cele\Y48G8AL.5
14 of 15
Yes
Yes
Cele\nol-2
1 of 15
No
No
Cele\nsun-4
1 of 15
No
No
Cele\nsun-5
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (2)
Atha\AT2G22400
9 of 9
Yes
Yes
Atha\AT4G40000
7 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\NCL1
13 of 15
Yes
Yes
Scer\NOP2
1 of 15
No
No
Scer\RCM1
1 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\SPAC17D4.04
11 of 12
Yes
Yes
Spom\SPAC23C4.17
11 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190376 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00008355
Drosophila simulans
Dsim\EG:EG0007.9
Drosophila sechellia
Dsec\GM12703
Drosophila erecta
Dere\EG:EG0007.9
Drosophila yakuba
Dyak\EG:EG0007.9
Drosophila ananassae
Dana\GF21493
Drosophila pseudoobscura pseudoobscura
Dpse\GA19379
Drosophila persimilis
Dper\GL21386
Drosophila willistoni
Dwil\GK17644
Drosophila virilis
Dvir\GJ16427
Drosophila mojavensis
Dmoj\GI16150
Drosophila grimshawi
Dgri\GH24818
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091502DF )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17015177
Glossina morsitans
Tsetse fly
Gmor\GMOY010148
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09235
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL013968
Anopheles darlingi
American malaria mosquito
Adar\ADAC008046
Anopheles gambiae
Malaria mosquito
Agam\AGAP002504
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010001
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02RK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA004408
Danaus plexippus
Monarch butterfly
Dple\DPOGS212221-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL016799
Apis florea
Little honeybee
Aflo\2323814292
Apis mellifera
Western honey bee
Amel\LOC411579
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP12860
Bombus terrestris
Buff-tailed bumblebee
Bter\15215937
Linepithema humile
Argentine ant
Lhum\LH13588
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00017a
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG030006
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04290
Tribolium castaneum
Red flour beetle
Tcas\TC009472
Pediculus humanus
Human body louse
Phum\PHUM474660
Rhodnius prolixus
Kissing bug
Rpro\RPRC008552
Cimex lectularius
Bed bug
Clec\CLEC011725
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI010136
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_06524
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X02WB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR000318
Ixodes scapularis
Black-legged tick
Isca\ISCW003251
Stegodyphus mimosarum
African social velvet spider
Smim\KFM70998.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM70999.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur25g01180
Tetranychus urticae
Two-spotted spider mite
Turt\tetur14g01180
Tetranychus urticae
Two-spotted spider mite
Turt\tetur25g01200
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_329423
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G04FO )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Nsun2
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000009504
Gallus gallus
Domestic chicken
Ggal\NSUN2
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (4)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
l(2)10685
3 of 10
CG8545
1 of 10
CG11109
1 of 10
Nsun5
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
Nsun2ex1
model of  intellectual disability
CEA
(Abbasi-Moheb et al., 2012)
Potential Models Based on Orthology ( 1 )
Modifiers Based on Experimental Evidence ( 0 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
NSUN2; NOP2/Sun RNA methyltransferase 2
14 of 15
610916
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Interactions Browser
View in Interactions Browser
Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
Nsun2 - CG17124
experimental knowledge based
(Guruharsha et al., 2011)
Nsun2 - Pi3K92E
anti tag coimmunoprecipitation, Identification by mass spectrometry
(Vinayagam et al., 2016)
Nsun2 - Rheb
anti tag coimmunoprecipitation, Identification by mass spectrometry
(Vinayagam et al., 2016)
Nsun2 - Tsc1
anti tag coimmunoprecipitation, Identification by mass spectrometry
(Vinayagam et al., 2016)
Nsun2 - capt
experimental knowledge based
(Guruharsha et al., 2011)
Nsun2 - sima
anti tag coimmunoprecipitation, Identification by mass spectrometry
(Vinayagam et al., 2016)
RNA-protein
Physical Interaction
Assay
References
Nsun2 - tRNA:Asp-GTC-1-1
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-10
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-11
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-12
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-2
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-3
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-4
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-5
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-6
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-7
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-8
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-1-9
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-2-1
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Nsun2 - tRNA:Asp-GTC-3-1
anti tag coimmunoprecipitation, cross-linking study, quantitative reverse transcription pcr
(Genenncher et al., 2018)
Summary of Genetic Interactions
esyN Network Diagram
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
External Data
Linkouts
BioGRID - A database of protein and genetic interactions.
DroID - A comprehensive database of gene and protein interactions.
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Metabolic Pathways
External Data
Linkouts
Genomic Location and Detailed Mapping Data
Chromosome (arm)
X
Recombination map

1-6

Cytogenetic map
4A5-4A6
Sequence location
X:4,111,156..4,113,734 [-]
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
4A5-4A6
Limits computationally determined from genome sequence between P{EP}CG2930EP1352 and P{EP}EP425
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location

1-6

(FlyBase, 2016)

1-6.0

(Comeron et al., 2012)
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (3)
Genomic Clones (14)
 

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (91)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    Other clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
     

    polyclonal

    (Genenncher et al., 2018)
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of

    Source for identity of: EG:EG0007.9 CG6133

    (Zhao, 1999.11)

    Source for identity of: Nsun2 CG6133

    (Abbasi-Moheb et al., 2012)
    Source for database merge of
    Additional comments

    FlyBase curator comment: the insertion in the "f06125" Exelixis line (PBac{WH}CG4865f06125) was originally assigned to the CG6133 gene in FBrf0179797, resulting in the "CG6133f06125" (FBal0161193) allele. However, FBrf0184340 shows that the insertion is actually within CG4865.

    (Bloomington Drosophila Stock Center, 2004.11.6)
    Other Comments
    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 35 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    Other crossreferences
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    InterPro - A database of protein families, domains and functional sites
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Synonyms and Secondary IDs (8)
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