Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dgt4 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\dgt4 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the failure of γ-tubulin to localize to the spindle, without affecting its localization to the pole, and the formation of an aberrantly long spindle when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the production of long spindles with low microtubule density, misaligned chromosomes/kinetochores and mitotic delay when assayed in S2 cells.
Named "dim γ-tubulin 4" for the decreased γ-tubulin staining of the spindle pole following treatment of S2 cells with dgt4 dsRNA.