General Information Symbol Dmel\ sizSpecies D. melanogaster Name schizo Annotation symbol CG32434 Feature type protein_coding_gene FlyBase ID FBgn0026179 Gene Model Status Current Stock availability 23 publicly
available Also Known As loner Genomic Location Chromosome (arm) 3L Recombination map 3-51 +/- 3 Cytogenetic map 78A5-78B1 Sequence location 3L:21,027,635..21,068,544 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
schizo is referred to in FlyBase by the symbol
Dmel\siz (CG32434, FBgn0026179). It is a protein_coding_gene from
Drosophila melanogaster . There is experimental evidence that it has the
molecular function : cadherin binding. There is experimental evidence that it is involved in the
biological process : myoblast fusion; central nervous system development; inter-male aggressive behavior; actin cytoskeleton organization; imaginal disc-derived wing morphogenesis.
58 alleles are reported . The
phenotypes of these alleles are annotated with: commissure; ventral nerve cord commissure; midline glial cell; embryonic myoblast; fusion competent cell. It has
4 annotated transcripts and
4 annotated polypeptides .
Protein features are: IQ motif, EF-hand binding site; Pleckstrin homology domain; Pleckstrin homology-like domain; SEC7-like; SEC7-like, alpha orthogonal bundle. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval midgut, larval hindgut, larval Malpighian tubules, adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult midgut, adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Gene sequence location is
3L:21027635..21068544 .
User Contributed Data
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It currently only tracks new links between this FlyBase report and other
FlyBase data classes (e.g. genes, references, stocks) or controlled
vocabulary terms (e.g. GO, anatomy terms).
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FB2013_03
FB2013_02
Controlled Vocabulary Terms
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. regulatory region
evidence=Reporter construct (in vivo)
External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
33
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
34
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
63
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
(32)
central nervous system, pupae P8
(33)
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
(34)
head, mated 4-day male
(32)
head, mated 20-day male
(32)
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
(63)
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
(28)
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
33
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
34
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
63
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
33
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
34
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
63
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
33
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
34
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
63
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
(33)
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
(34)
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
(63)
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
33
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
34
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
63
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
32
central nervous system, pupae P8
33
head, virgin 1-day female
21
head, virgin 4-day female
20
head, virgin 20-day female
19
head, mated 1-day female
20
head, mated 4-day female
19
head, mated 20-day female
16
head, mated 1-day male
34
head, mated 4-day male
32
head, mated 20-day male
32
salivary gland, larvae L3 wandering
8
salivary gland, white prepupae
63
digestive system, larvae L3 wandering
21
digestive system, 1-day adult
13
digestive system, 4-day adult
17
digestive system, 20-day adult
16
fat body, larvae L3 wandering
6
fat body, white prepupae
13
fat body, pupae P8
12
carcass, larvae L3 wandering
28
carcass, 1-day adult
15
carcass, 4-day adult
16
carcass, 20-day adult
18
ovary, virgin 4-day female
20
ovary, mated 4-day female
17
testis, mated 4-day male
9
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
40
embryo 04-06hr
59
embryo 06-08hr
54
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
37
embryo 16-18hr
34
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
(40)
embryo 04-06hr
(59)
embryo 06-08hr
(54)
embryo 08-10hr
(32)
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
(37)
embryo 16-18hr
(34)
embryo 18-20hr
(32)
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
(27)
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
40
embryo 04-06hr
59
embryo 06-08hr
54
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
37
embryo 16-18hr
34
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
40
embryo 04-06hr
59
embryo 06-08hr
54
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
37
embryo 16-18hr
34
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
40
embryo 04-06hr
59
embryo 06-08hr
54
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
37
embryo 16-18hr
34
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
(40)
embryo 04-06hr
(59)
embryo 06-08hr
(54)
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
(37)
embryo 16-18hr
(34)
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
40
embryo 04-06hr
59
embryo 06-08hr
54
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
37
embryo 16-18hr
34
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
40
embryo 04-06hr
59
embryo 06-08hr
54
embryo 08-10hr
32
embryo 10-12hr
24
embryo 12-14hr
25
embryo 14-16hr
37
embryo 16-18hr
34
embryo 18-20hr
32
embryo 20-22hr
21
embryo 22-24hr
21
larva L1
12
larva L2
13
larva L3 12hr old
10
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
22
larva L3 puffstage 7-9
27
white prepupae new
23
white prepupae 12hr
18
white prepupae 24hr
16
pupae 2d postWPP
20
pupae 3d postWPP
16
pupae 4d postWPP
21
adult male 01day
19
adult male 05day
23
adult male 30day
23
adult female 01day
17
adult female 05day
17
adult female 30day
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
12
Schneider line 2 Sg4
11
embryonic 1182-4H
8
embryonic GM2
15
embryonic Kc167
7
embryonic S1
9
embryonic S3
24
leg disc CME L1
14
wing disc CME-W2
14
wing disc ML-DmD8
5
wing disc ML-DmD9
6
wing disc ML-DmD16-c3
10
wing disc ML-DmD21
2
wing disc ML-DmD32
5
haltere disc ML-DmD17-c3
5
eye-antennal disc ML-DmD11
8
antennal disc ML-DmD20-c5
6
mixed discs ML-DmD4-c1
5
CNS ML-DmBG1-c1
12
CNS ML-DmBG2-c2
21
tumorous blood cells mbn2
19
ovary fGS/OSS
5
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
15
cold shock, 4-day adult
11
heat shock, 4-day adult
14
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
13
Cadmium 100 mM 48 hrs, 4-day adult
19
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
9
Zinc 4.5 mM 48 hrs, 4-day adult
21
Ethanol 2.5% 3 hrs, larvae L3
22
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
6
Caffeine 1.5 mg/ml 4 hrs, larvae L3
9
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
19
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
6
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 34 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 24 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Not disrupted in Transgenic Constructs & Insertions
Transgenic Constructs UAS construct
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
characterization construct
Insertions insertion of mobile activating element
miscellaneous insertions
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
insertion of enhancer trap binary system
Gene Ontology: Function, Process
& Cellular Component ( 14 unique terms ) Terms Based on
Experimental Evidence ( 6 terms ) Molecular Function inferred from direct assay
Biological Process inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 9 terms ) Molecular Function inferred from biological aspect of ancestor with PANTHER:PTN000070561
(assigned by RefGenome)
non-traceable author statement
Biological Process non-traceable author statement
inferred from biological aspect of ancestor with PANTHER:PTN000070822
(assigned by RefGenome)
Cellular Component inferred from biological aspect of ancestor with PANTHER:PTN000070822
(assigned by RefGenome)
inferred from biological aspect of ancestor with PANTHER:PTN000070822
(assigned by RefGenome)
inferred from biological aspect of ancestor with PANTHER:PTN000070822
(assigned by RefGenome)
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (54)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6H72X8 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Drosophila pseudoobscura pseudoobscura
Orthologs in non-Drosophila Dipterans
(EOG6WSWJX )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG698SVS )
Apis mellifera
Western honey bee
Amel\GB46262
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG004818
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH11658
Atta cephalotes
Leafcutter ant
Acep\ACEP18929
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO13070
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL16840
Linepithema humile
Argentine ant
Lhum\LH13058
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB24117
Solenopsis invicta
Red fire ant
Sinv\SINV17769
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6H189S )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6W71P8 )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (3)AAA Orthologs (4)
based on analysis using Dmel annotation version 4.3
Stocks & Reagents Stocks Listed in FlyBase ( 23 )Harvard VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 64 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology "schizo" means "split" in German.
Identification Relationship to Other Genes Source for database identity of Source for identity of: loner CG32434
Source for database merge of Source for merge of: CG10577 CG12980 CG12981
Source for merge of: siz loner
Additional comments Annotations CG10577, CG12980 and CG12981 merged as CG32434 in release 3 of the genome annotation.
Source for identity of loner CG32434 was sequence comparison (date:031005).
Other Comments Two EMS induced alleles were identified in a screen for mutations affecting commissure formation in the CNS of the embryo.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
- A database of transcriptional regulatory elements.
Synonyms & Secondary IDs
( 10 )Reported As Symbol Synonym CG32434
(
Cox et al., 2004 ,
Milchanowski et al., 2004 ,
Onel et al., 2004 ,
Matyash et al., 2004 ,
Giot et al., 2003 ,
Lawniczak and Begun, 2004 ,
Keleman et al., 2009.8.5 ,
Gupta et al., 2009 ,
Morozova et al., 2006 ,
Aerts et al., 2010 ,
Ni et al., 2010.12.1 )
loner
(
Donaldson, 2003 ,
Chen and Olson, 2004 ,
Chen et al., 2003 ,
Richardson and Baylies, 2005 ,
Taylor, 2003 ,
FlyBase, 1996- ,
Reeves and Posakony, 2005 ,
Rochlin et al., 2007 ,
Richardson et al., 2007 ,
Wang et al., 2012 )
Name Synonym schizo
(
Hummel et al., 1999 ,
Dottermusch-Heidel et al., 2012 ,
Raghu et al., 2009 ,
Gupta et al., 2009 ,
Edwards et al., 2009 ,
Edwards et al., 2009 ,
Casanova, 2007 )
Secondary FlyBase
IDs FBgn0037047 FBgn0037048 FBgn0037049 FBgn0052434 References ( 66 )Generate a list of List References by type
Recent research papers ( 5 )
Dottermusch-Heidel et al., 2012, Dev. Biol. 368(1): 18--27The Arf-GEF Schizo/Loner regulates N-cadherin to induce fusion competence of Drosophila myoblasts. [FBrf0218661] Wang et al., 2012, J. Cell Sci. 125(2): 461--472GBF1 (Gartenzwerg)-dependent secretion is required for Drosophila tubulogenesis. [FBrf0217573] Carreira et al., 2011, BMC Dev. Biol. 11: 32Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273] Johnson et al., 2011, Mol. Biol. Cell 22(23): 4513--4526Role for a Cindr-Arf6 axis in patterning emerging epithelia. [FBrf0216708] Zwarts et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(41): 17070--17075Complex genetic architecture of Drosophila aggressive behavior. [FBrf0216413]
Recent reviews (0)
All reviews listed in FlyBase were published before 2011