DmPar-6, DmPar6, DPar-6, DPar6
PDZ domain transcription factor required for asymmetric cell division of neuroblasts and for the maintenance of oocyte cell fate - regulates gene expression in muscles and in circadian clock neurons.
Please see the JBrowse view of Dmel\par-6 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.51
2.1 (longest cDNA)
351 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\par-6 using the Feature Mapper tool.
Comment: expressed in more cells, but more concentrated in epithelial tissues
Comment: apical crescent at interphase and metaphase; delocalized at interphase
Comment: expressed in all cells
Comment: peribouton area
GBrowse - Visual display of RNA-Seq signals
View Dmel\par-6 in GBrowse 21-58
1-58.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: cells become round and detached. Kc167 cells are unaffected.