HOAP, anon1G5, HP1/ORC-associated protein, anon fe 1G5, p55
Gene model reviewed during 5.39
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Interacts (via C-terminus) with Su(var)205 dimer (via hinge and chromoshadow domain) and with moi to form the terminin telomere-capping complex. Interacts with HP6, which is also part of the terminin complex.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\cav using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\cav in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
cav protein binds specific heterochromatin satellite DNA sequences in gel mobility shift assays.
Mutant larvae have increased frequencies of telomeric fusions in brain cells.
Quantifying rates of protein sequence divergence within and between species reveals that the Drosophila genome harbors a substantial proportion of genes with a very high divergence rate.
The gene is named "caravaggio", because the linear multicentric chromosomes that characterize the mutant phenotype resemble little trains; there is an Italian train named "Caravaggio" in memory of the famous painter.
Named "caravaggio" after an Italian train, as the multicentric chromosomes observed in mutants resemble little trains of chromosomes.