cIF2, dIF2, IF2, eukaryotic initiation factor 5B, cytoplasmic Initiation Factor 2
Please see the JBrowse view of Dmel\eIF5B for information on other features
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Gene model reviewed during 5.41
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.50
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eIF5B using the Feature Mapper tool.
Comment: punctate expression in adult brain cortex
GBrowse - Visual display of RNA-Seq signals
View Dmel\eIF5B in GBrowse 23-8
3-8
3-6.9
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: cIF2 CG10840
Source for merge of: eIF5B anon-WO0118547.362
Source for merge of: cIF2 CG14970
Annotations CG10840 and CG14970 merged as CG10840 in release 3 of the genome annotation.
Source for merge of eIF5B anon-WO0118547.362 was sequence comparison ( date:051113 ).
Area matching Drosophila EST AA803203. Probable intron in gene represented by EST AA803203.
Identification: Protein that interacts with vas protein in a yeast two-hybrid assay.
Mutations in eIF5B are recessive lethal. Ovaries derived from homozygous germ line clones contain fewer egg chambers than normal, and those egg chambers that do form often have too many nurse cells and two oocytes.