FlyBase Gene Report: Dmel\eIF5B

General Information

Symbol

Dmel\eIF5B

Species

D. melanogaster

Name

eukaryotic translation initiation factor 5B

Annotation Symbol

CG10840

Feature Type

protein_coding_gene

FlyBase ID

FBgn0026259

Gene Model Status

Current

Stock Availability

16 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

cIF2, dIF2, IF2, cytoplasmic Initiation Factor 2, eukaryotic initiation factor 5B

Key Links

Genomic Location

Cytogenetic map

63E1-63E1

Sequence location

3L:3,428,658..3,460,977 [-]

Recombination map

3-8

RefSeq locus

NT_037436 REGION:3428658..3460977

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (9 terms)

Molecular Function (5 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with UniProtKB:P09052

(Carrera et al., 2000)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

enables DEAD/H-box RNA helicase binding

traceable author statement

(Johnstone and Lasko, 2001)

enables GTP binding

inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225

(InterPro Project Members, 2004-)

enables GTPase activity

inferred from electronic annotation with InterPro:IPR000795

(InterPro Project Members, 2004-)

inferred from sequence or structural similarity with UniProtKB:P39730

(Gene Ontology Curators, 2002-)

enables translation initiation factor activity

inferred from biological aspect of ancestor with PANTHER:PTN001897651

(GO Reference Genome Project, 2011-)

inferred from sequence or structural similarity with UniProtKB:O60841

(Gene Ontology Curators, 2002-)

inferred from sequence or structural similarity

(Lasko, 2000)

Biological Process (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in formation of cytoplasmic translation initiation complex

inferred from sequence or structural similarity with UniProtKB:P39730

(Gene Ontology Curators, 2002-)

involved_in translational initiation

inferred from sequence or structural similarity

(Lasko, 2000)

inferred from biological aspect of ancestor with PANTHER:PTN001897651

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN001897651

(GO Reference Genome Project, 2011-)

located_in cytoplasm

inferred from sequence or structural similarity

(Lasko, 2000)

Gene Group (FlyBase)

CYTOPLASMIC TRANSLATION INITIATION FACTORS

TRANSLATIONAL GTPASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

GTPase activity
RHEA 19669:

Summaries

Gene Group (FlyBase)

CYTOPLASMIC TRANSLATION INITIATION FACTORS -: Cytoplasmic (or eukaryotic) translation initiation factors function in the initiation stage of ribosome-mediated translation in the cytoplasm. (Adapted from FBrf0233552 and PMID:20094052).
TRANSLATIONAL GTPASES -: Translational GTPases are a family of GTPases that facilitate and control protein synthesis on the ribosome. (Adapted from PMID:26971860).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\eIF5B for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VZP5)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.41

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.50

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

eIF5B-RB

FBtr0073144

NM_143717

4107

1144

eIF5B-RC

FBtr0309836

NM_001259670

4378

1144

eIF5B-RD

FBtr0309837

NM_001259671

3952

1090

eIF5B-RE

FBtr0309838

NM_001259672

4006

1108

eIF5B-RF

FBtr0309839

NM_001259673

4403

1144

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

eIF5B-PB

FBpp0073003

127.2

1144

5.17

FBpp0301570

127.2

1144

5.17

FBpp0301571

121.1

1090

5.15

FBpp0301572

123.3

1108

5.16

FBpp0301573

127.2

1144

5.17

Q9VZP5

NP_001246602

AFH04273

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1144 aa isoforms: eIF5B-PB, eIF5B-PC, eIF5B-PF

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eIF5B using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

3.02

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Expression Deduced from Reporters

Reporter: PBac{768.FSVS-0}eIF5B^CPTI003501

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult brain cell body rind

Comment: punctate expression in adult brain cortex

(Knowles-Barley, 2011.8.24)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\eIF5B in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\eIF5B

View exonic expression by tissue for Dmel\eIF5B

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

44261/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0026259

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0026259

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0026259

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10840

Flygut - An atlas of the Drosophila adult midgut

FBgn0026259

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 15 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of eIF5B

Transgenic constructs containing regulatory region of eIF5B

Aberrations (Deficiencies and Duplications) ( 6 )

Inferred from experimentation ( 6 )

Gene disrupted in

Df(3L)ED208

(Marygold et al., 2007)

Df(3L)Exel6094

(Marygold et al., 2007)

Df(3L)G5

(Carrera et al., 2000)

Df(3L)HR119

(Carrera et al., 2000)

Df(3L)HR232

(Carrera et al., 2000)

Gene not disrupted in

Df(3L)armi^Δ1

(Olivieri et al., 2010)

Inferred from location ( 4 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

eIF5B^GD7105

lethal | pupal stage, with Scer\GAL4^pnr-MD237

eIF5B^GD7105

lethal | recessive

lethal - all die before end of larval stage | recessive

eIF5B^unspecified

lethal - all die during larval stage, with Scer\GAL4^Mef2.PR

eIF5B^GD7105

partially lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

eIF5B^GD7105

partially lethal, with Scer\GAL4^tin.CΔ4

eIF5B^GD7105

viable

eIF5B^EY01401

Sterility

Allele

fertile

eIF5B^EY01401

Other Phenotypes

Allele

some die during larval stage | recessive

eIF5B^unspecified

some die during pupal stage, with Scer\GAL4^tin.CΔ4

eIF5B^GD7105

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (8)

Hsap\EIF5B

12 of 14

Yes

3 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (8)

Rnor\Eif5b

12 of 14

Yes

Rnor\Mtif2

3 of 14

Rnor\Eif5b-ps1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (7)

Mmus\Eif5b

11 of 14

Yes

3 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (5)

Xtro\eif5b

10 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (9)

Drer\eif5b

13 of 14

Yes

3 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (9)

Cele\iffb-1

13 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (8)

Agam\AgaP_AGAP004824

12 of 12

Yes

3 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (14)

Atha\AT1G21160

12 of 13

Yes

Atha\AT1G76720

12 of 13

Yes

Atha\AT1G76810

12 of 13

Yes

Atha\AT1G76820

12 of 13

Yes

Atha\AT2G27700

9 of 13

Yes

Atha\AT4G11160

3 of 13

Atha\FUG1

3 of 13

Atha\AT2G37120

1 of 13

Yes

Atha\AT3G09735

1 of 13

Yes

Atha\AT3G53370

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (7)

Scer\FUN12

12 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (6)

Spom\SPAC56F8.03

11 of 12

Yes

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (2)

Ecol\infB

3 of 11

Yes

Ecol\selB

1 of 11

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:eIF5B. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (20)

mIF2

5 of 13

waw

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

eIF5B^KK105498

ameliorates frontotemporal dementia and/or amyotrophic lateral sclerosis 1

modeled by Zzzz\poly-GR^50.UAS.EGFP

(Lee et al., 2016)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

EIF5B; eukaryotic translation initiation factor 5B

12 of 14

606086

MTIF2; mitochondrial translational initiation factor 2

3 of 14

603766

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

eIF5B - rictor

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF5B - vas

two hybrid, pull down, anti tag western blot

(Dehghani and Lasko, 2016, Johnstone and Lasko, 2004, Carrera et al., 2000)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

vas

enhanceable

eIF5B

(Carrera et al., 2000)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

68928

DroID - A comprehensive database of gene and protein interactions.

FBgn0026259

MIST (protein-protein) - An integrated Molecular Interaction Database

44261

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

GTP hydrolysis and joining of the 60S ribosomal subunit

Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-8

Cytogenetic map

63E1-63E1

Sequence location

3L:3,428,658..3,460,977 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

63E1-63E1

Limits computationally determined from genome sequence between P{PZ}kst⁰¹³¹⁸ and P{PZ}Sc2⁰⁵⁶³⁴

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

63D-63D

(Carrera, 1999.4.14)

63D2-63D3

(Lasko, 1999.3.3)

Experimentally Determined Recombination Data

Location

3-8

(FlyBase, 2016)

3-6.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (16)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

81463

y¹ v¹; P{TKO.GS04711}attP40

30626

y¹ w^*; Mi{MIC}eIF5B^MI00125

19641

y¹ w^67c23; P{EPgy2}eIF5B^EY01401/TM3, Sb¹

37333

y¹ w^*; Mi{MIC}eIF5B^MI02930/TM3, Sb¹ Ser¹

44179

y¹ w^*; Mi{MIC}eIF5B^MI07293/TM3, Sb¹ Ser¹

44418

y¹ sc^* v¹ sev²¹; P{TRiP.GL01593}attP2/TM3, Sb¹

Kyoto

115412

w¹¹¹⁸; PBac{768.FSVS-0}eIF5B^CPTI003501

NIG-Fly

10840R-1

P{NIG.10840R}1

10840R-3

P{NIG.10840R}3

HMJ22212

y¹ v¹; P{TRiP.HMJ22212}attP40/CyO

VDRC

v109782

P{KK105498}VIE-260B

v31366

w¹¹¹⁸; P{GD7105}v31366/CyO

More stocks available...

Genomic Clones (30)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (68)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0026259

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0026259

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

New stable cell line derived from S2-unspecified : S2 cell lines expressing circCG32369, circMCPH1, circeIF5B, circrl, circPde11, circCG17715, circzfh2, circTao, circcrol, circdrn, circMeltrin, circpxb, circfru, circdati, circstw, circSarm, circStim, circCG2991, circPvr, circHil, circmub, circsxc, circbnl, and circCG9743 were created. The author reports new stable cell lines S2-circMCPH1, S2-circCG32369, S2-Flag-Ddx56 , and S2-Flag-gw.
(Su et al., 2024)

Other Comments

Area matching Drosophila EST AA803203. Probable intron in gene represented by EST AA803203.

(Davies, 2001.3.15)

Identification: Protein that interacts with vas protein in a yeast two-hybrid assay.

(Johnstone et al., 1999)

Mutations in eIF5B are recessive lethal. Ovaries derived from homozygous germ line clones contain fewer egg chambers than normal, and those egg chambers that do form often have too many nurse cells and two oocytes.

(Johnstone et al., 1999)

Relationship to Other Genes

Source for database merge of

Source for merge of: cIF2 CG10840

(Bayraktaroglu, 2000.8.7)

Source for merge of: eIF5B anon-WO0118547.362

(FlyBase, 1996-)

Source for merge of: cIF2 CG14970

(FlyBase Genome Annotators, 2002-2003)

Additional comments

Annotations CG10840 and CG14970 merged as CG10840 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Source for merge of eIF5B anon-WO0118547.362 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

(Johnstone et al., 1999)

CG10840

(National Institute of Genetics Fly Stocks, 2023-, Vasudevan et al., 2020, Marygold et al., 2017, Hosono et al., 2015, Bridon et al., 2012, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Bayraktaroglu, 2000.8.7, Lasko, 2000)

CG14970

EIF5B

(Linsalata et al., 2019)

Eif5b

(Bridon et al., 2012)

IF2

(Brogna et al., 2002, Macdonald, 2001)

anon-WO0118547.362

cIF2

(Mukherjee et al., 2014, Foley and O'Farrell, 2004, Giot et al., 2003, Bayraktaroglu, 2000.8.7, Lasko, 1999.3.3)

dIF2

(Johnstone and Lasko, 2001, Carrera et al., 2000, Lasko, 2000)

yIF2

(Carrera, 1999.4.14)

Name Synonyms

cytoplasmic Initiation Factor 2

(Lasko, 1999.3.3)

eIF5B

(Davis et al., 2011)

eukaryotic initiation factor 5B

(Bridon et al., 2012, Pek and Kai, 2011)

eukaryotic translation initiation factor 5B

Secondary FlyBase IDs

FBgn0035446
FBgn0035447
FBgn0062068

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 60 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

44261

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VZP5

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VZP5

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

44261/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0026259

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0026259

FlyMine - An integrated database for Drosophila genomics

FBgn0026259

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG10840

MARRVEL_MODEL - MARRVEL (model organism gene)

44261

Linkouts

BioGRID - A database of protein and genetic interactions.

68928

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0026259

DroID - A comprehensive database of gene and protein interactions.

FBgn0026259

DRSC - Results frm RNAi screens

FBgn0026259

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0026259

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0026259

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10840

Flygut - An atlas of the Drosophila adult midgut

FBgn0026259

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0026259

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC007444

MIST (protein-protein) - An integrated Molecular Interaction Database

44261

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

GTP hydrolysis and joining of the 60S ribosomal subunit

References (97)

The following external sites may use different assemblies or annotations than FlyBase.

3.02

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