FlyBase Gene Report: Dmel\eIF5B

CYTOPLASMIC TRANSLATION INITIATION FACTORS -: Cytoplasmic (or eukaryotic) translation initiation factors function in the initiation stage of ribosome-mediated translation in the cytoplasm. (Adapted from FBrf0233552 and PMID:20094052).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\eIF5B or the JBrowse view of Dmel\eIF5B for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.41

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.50

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

eIF5B-RB

FBtr0073144

NM_143717

4107

1144

eIF5B-RC

FBtr0309836

NM_001259670

4378

1144

eIF5B-RD

FBtr0309837

NM_001259671

3952

1090

eIF5B-RE

FBtr0309838

NM_001259672

4006

1108

eIF5B-RF

FBtr0309839

NM_001259673

4403

1144

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

eIF5B-PB

FBpp0073003

127.2

1144

5.17

NP_651974

AAF47774

eIF5B-PC

FBpp0301570

127.2

1144

5.17

NP_001246599

AFH04270

eIF5B-PD

FBpp0301571

121.1

1090

5.15

NP_001246600

AFH04271

eIF5B-PE

FBpp0301572

123.3

1108

5.16

NP_001246601

AFH04272

eIF5B-PF

FBpp0301573

127.2

1144

5.17

NP_001246602

AFH04273

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1144 aa isoforms: eIF5B-PB, eIF5B-PC, eIF5B-PF

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eIF5B using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Gene Ontology (8 terms)

Molecular Function (5 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

protein binding

inferred from physical interaction with UniProtKB:P09052

(assigned by UniProt )

(Carrera et al., 2000)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

DEAD/H-box RNA helicase binding

traceable author statement

(Johnstone and Lasko, 2001)

GTP binding

inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

GTPase activity

inferred from electronic annotation with InterPro:IPR000795

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

translation initiation factor activity

inferred from biological aspect of ancestor with PANTHER:PTN000561881

(assigned by GO_Central )

(Gaudet et al., 2011)

inferred from sequence or structural similarity

(Lasko, 2000)

Biological Process (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

translational initiation

inferred from sequence or structural similarity

(Lasko, 2000)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

cytoplasm

inferred from sequence or structural similarity

(Lasko, 2000)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Expression Deduced from Reporters

Reporter: PBac{768.FSVS-0}eIF5B^CPTI003501

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult brain cell body rind

Comment: punctate expression in adult brain cortex

(Knowles-Barley, 2011.8.24)

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\eIF5B in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\eIF5B

View exonic expression by tissue for Dmel\eIF5B

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0026259

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG10840-RB

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10840

Flygut - An atlas of the Drosophila adult midgut

FBgn0026259

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 14 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of eIF5B

Transgenic constructs containing regulatory region of eIF5B

Deletions and Duplications ( 6 )

Disrupted in

Df(3L)ED208

(Marygold et al., 2007)

Df(3L)Exel6094

(Marygold et al., 2007)

Df(3L)G5

(Carrera et al., 2000)

Df(3L)HR119

(Carrera et al., 2000)

Df(3L)HR232

(Carrera et al., 2000)

Not disrupted in

Df(3L)armi^Δ1

(Olivieri et al., 2010)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

eIF5B^GD7105

lethal | pupal stage, with Scer\GAL4^pnr-MD237

eIF5B^GD7105

lethal | recessive

lethal - all die before end of larval stage | recessive

eIF5B^unspecified

lethal - all die during larval stage, with Scer\GAL4^Mef2.PR

eIF5B^GD7105

partially lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

eIF5B^GD7105

partially lethal, with Scer\GAL4^tin.CΔ4

eIF5B^GD7105

viable

eIF5B^EY01401

Sterility

Allele

fertile

eIF5B^EY01401

Other Phenotypes

Allele

some die during larval stage | recessive

eIF5B^unspecified

some die during pupal stage, with Scer\GAL4^tin.CΔ4

eIF5B^GD7105

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\EIF5B

12 of 15

Yes

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Eif5b

12 of 15

Yes

Rattus norvegicus (Norway rat) (1)

Rnor\Eif5b

10 of 13

Yes

Xenopus tropicalis (Western clawed frog) (2)

Xtro\eif5b

4 of 12

Yes

Xtro\hbs1l

1 of 12

Danio rerio (Zebrafish) (1)

Drer\eif5b

10 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\iffb-1

12 of 15

Yes

Arabidopsis thaliana (thale-cress) (5)

Atha\AT1G21160

8 of 9

Yes

Atha\AT1G76720

8 of 9

Yes

Atha\AT1G76810

6 of 9

Yes

Atha\AT1G76820

6 of 9

Yes

Atha\AT2G27700

5 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\FUN12

12 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC56F8.03

9 of 12

Yes

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091903ZC )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\eIF5B

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA10589

Drosophila persimilis

Dper\GL13259

Drosophila willistoni

Dwil\GK20375

Drosophila virilis

Dvir\GJ13104

Drosophila mojavensis

Dmoj\GI12960

Drosophila grimshawi

Dgri\GH15356

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915040X )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17006465

Musca domestica

House fly

Mdoa\17006832

Glossina morsitans

Tsetse fly

Gmor\GMOY002327

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_10990

Mayetiola destructor

Hessian fly

Mdes\Mdes002744

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL009241

Anopheles darlingi

American malaria mosquito

Adar\ADAC010464

Anopheles gambiae

Malaria mosquito

Agam\AGAP004824

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ015682

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0MPA )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA001265

Danaus plexippus

Monarch butterfly

Dple\DPOGS205159-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL003611

Heliconius melpomene

Postman butterfly

Hmel\HMEL009831

Apis florea

Little honeybee

Aflo\2262004036

Apis mellifera

Western honey bee

Amel\GB51257

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP20106

Bombus terrestris

Buff-tailed bumblebee

Bter\15205929

Linepithema humile

Argentine ant

Lhum\LH26135

Linepithema humile

Argentine ant

Lhum\LH14933

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:00068f

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG012245

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_04484

Tribolium castaneum

Red flour beetle

Tcas\GLEAN_07444

Pediculus humanus

Human body louse

Phum\PHUM409240

Pediculus humanus

Human body louse

Phum\PHUM506500

Rhodnius prolixus

Kissing bug

Rpro\RPRC001448

Cimex lectularius

Bed bug

Clec\CLEC012286

Cimex lectularius

Bed bug

Clec\CLEC012285

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI007156

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_07251

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0EG1 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR015134

Strigamia maritima

European centipede

Smar\SMAR004680

Ixodes scapularis

Black-legged tick

Isca\ISCW009538

Stegodyphus mimosarum

African social velvet spider

Smim\KFM78349.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM66345.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur21g00400

Tetranychus urticae

Two-spotted spider mite

Turt\tetur21g00390

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_205517

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G114V )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Eif5B_1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Eif5bL

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Eif5B_2

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Eif5B

Gallus gallus

Domestic chicken

Ggal\EIF5B

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (1)

Gene Symbol

Score

Source

Alignment

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

EIF5B; eukaryotic translation initiation factor 5B

12 of 15

606086

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

eIF5B - rictor

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

eIF5B - vas

two hybrid, pull down, anti tag western blot

(Dehghani and Lasko, 2016, Johnstone and Lasko, 2004, Carrera et al., 2000)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

vas

enhanceable

eIF5B

(Carrera et al., 2000)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

68928

DroID - A comprehensive database of gene and protein interactions.

FBgn0026259

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

44261

MIST (protein-protein) - An integrated Molecular Interaction Database

eIF5B

Pathways

Gene Group - Pathway Membership (FlyBase)

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-8

Cytogenetic map

63E1-63E1

Sequence location

3L:3,428,658..3,460,977 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

63E1-63E1

Limits computationally determined from genome sequence between P{PZ}kst⁰¹³¹⁸ and P{PZ}Sc2⁰⁵⁶³⁴

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

63D-63D

(Carrera, 1999.4.14)

63D2-63D3

(Lasko, 1999.3.3)

Experimentally Determined Recombination Data

Location

3-8

(FlyBase, 2016)

3-6.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (15)

Bloomington

81463

y¹ v¹; P{TKO.GS04711}attP40

30626

y¹ w^*; Mi{MIC}eIF5B^MI00125

19641

y¹ w^67c23; P{EPgy2}eIF5B^EY01401/TM3, Sb¹

37333

y¹ w^*; Mi{MIC}eIF5B^MI02930/TM3, Sb¹ Ser¹

44179

y¹ w^*; Mi{MIC}eIF5B^MI07293/TM3, Sb¹ Ser¹

44418

y¹ sc^* v¹ sev²¹; P{TRiP.GL01593}attP2/TM3, Sb¹

64446

y¹ w^*; Mi{PT-GFSTF.0}eIF5B^{MI05586-GFSTF.0}/TM3, Sb¹ Ser¹

Harvard

c02932

PBac{PB}eIF5B^c02932

Kyoto

115412

w¹¹¹⁸; PBac{768.FSVS-0}eIF5B^CPTI003501

VDRC

v109782

P{KK105498}VIE-260B

v31365

w¹¹¹⁸; P{GD7105}v31365

v31366

w¹¹¹⁸; P{GD7105}v31366/CyO

More stocks available...

Genomic Clones (30)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (77)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0026259

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0026259

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

44261

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: cIF2 CG10840

(Bayraktaroglu, 2000.8.7)

Source for merge of: eIF5B anon-WO0118547.362

(FlyBase, 1996-)

Source for merge of: cIF2 CG14970

(FlyBase Genome Annotators, 2002-2003)

Additional comments

Annotations CG10840 and CG14970 merged as CG10840 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Source for merge of eIF5B anon-WO0118547.362 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Other Comments

Area matching Drosophila EST AA803203. Probable intron in gene represented by EST AA803203.

(Davies, 2001.3.15)

Identification: Protein that interacts with vas protein in a yeast two-hybrid assay.

(Johnstone et al., 1999)

Mutations in eIF5B are recessive lethal. Ovaries derived from homozygous germ line clones contain fewer egg chambers than normal, and those egg chambers that do form often have too many nurse cells and two oocytes.

(Johnstone et al., 1999)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 57 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

44261

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0026259

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10840

Flygut - An atlas of the Drosophila adult midgut

FBgn0026259

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

44261

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG10840

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

modMine - A data warehouse for the modENCODE project

FBgn0026259

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

GTP hydrolysis and joining of the 60S ribosomal subunit

Linkouts

BioGRID - A database of protein and genetic interactions.

68928

DroID - A comprehensive database of gene and protein interactions.

FBgn0026259

DRSC - Results frm RNAi screens

FBgn0026259

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0026259

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG10840-RB

FlyMine - An integrated database for Drosophila genomics

FBgn0026259

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

44261

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

RNA transport

MIST (protein-protein) - An integrated Molecular Interaction Database

eIF5B

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

GTP hydrolysis and joining of the 60S ribosomal subunit

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

(Johnstone et al., 1999)

CG10840

(Marygold et al., 2017, Hosono et al., 2015, Bridon et al., 2012, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Bayraktaroglu, 2000.8.7, Lasko, 2000)

CG14970

Eif5b

(Bridon et al., 2012)

IF2

(Brogna et al., 2002, Macdonald, 2001)

anon-WO0118547.362

cIF2

(Mukherjee et al., 2014, Foley and O'Farrell, 2004, Giot et al., 2003, Bayraktaroglu, 2000.8.7, Lasko, 1999.3.3)

dIF2

(Johnstone and Lasko, 2001, Carrera et al., 2000, Lasko, 2000)

yIF2

(Carrera, 1999.4.14)

Name Synonyms

cytoplasmic Initiation Factor 2

(Lasko, 1999.3.3)

eIF5B

(Davis et al., 2011)

eukaryotic initiation factor 5B

(Bridon et al., 2012, Pek and Kai, 2011)

eukaryotic translation initiation factor 5B

Secondary FlyBase IDs

FBgn0035446
FBgn0035447
FBgn0062068

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (81)

Report Sections

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