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Gene Dmel\RpL23A

General Information
Symbol	Dmel\RpL23A	Species	D. melanogaster
Name	Ribosomal protein L23A	Annotation symbol	CG7977
Feature type	protein_coding_gene	FlyBase ID	FBgn0026372
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	L23a
Genomic Location
Chromosome (arm)	3L	Recombination map	3-
Cytogenetic map	62A10-62A10	Sequence location	3L:1,667,192..1,668,677 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein L23A is referred to in FlyBase by the symbol Dmel\RpL23A (CG7977, FBgn0026372). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: centrosome duplication. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nucleotide-binding, alpha-beta plait; Ribosomal protein L23/L15e; Ribosomal protein L23/L25, N-terminal; Ribosomal protein L23/L25, conserved site; Ribosomal protein L25/L23. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634917_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of RpL23A. Gene sequence location is 3L:1667192..1668677.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Clones FGM004A04 EK173949 Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood ribosome day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood References Alonso and Santaren, 2006, J. Proteome Res. 5(8): 2025--2032
FB2012_01	References Müller et al., 2010, EMBO J. 29(19): 3344--3357 Controlled Vocabulary Terms centrosome duplication Sequence features HFA08694
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 62A10-62A10   Limits computationally determined from genome sequence between P{EP}rhoEP3704&P{PZ}l(3)0622606226 and P{PZ}dlt04276
Experimentally Determined Cytological Location
Cytogenetic map Notes References 62C-62C   (determined by in situ hybridisation)   (Hursh, 1995.7.5)
Experimentally Determined Recombination Data
Location	3- (Hursh, 1995.7.5)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpL23A for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpL23A-RA FBtr0072805  NM_079162   1039   277
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpL23A-PA   FBpp0072687   29.5   277   11.66     NP_523886   AAF47545
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L23/L25, conserved site (IPR001014) Ribosomal protein L23/L25, N-terminal (IPR005633) Nucleotide-binding, alpha-beta plait (IPR012677) Ribosomal protein L23/L15e (IPR012678) Ribosomal protein L25/L23 (IPR013025)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201320   AA201424   AA201930   AA202764   AA246509   AA246985   AA263201   AA391933   AA392363   AA433249   AA438404   AA439272   AA538588   AA541024   AA567050   AA567086   AA694866   AA694878   AA695004   AA695035   AA695159   AA695387   AA695629   AA695636   AA695737   AA695750   AA696021   AA696067   AA696549   AA696810   AA696825   AA696944   AA696978   AA697163   AA698761   AA735293   AA735319   AA735519   AA735770   AA736184   AA736224   AA801686   AA801712   AA801765   AA801775   AA801834   AA801920   AA802034   AA802103   AA802257   AA802287   AA802319   AA802384   AA802587   AA802706   AA802847   AA802946   AA802956   AA802965   AA802966   AA803057   AA803147   AA803204   AA803348   AA803425   AA803581   AA803589   AA803591   AA803699   AA803748   AA803763   AA803840   AA803857   AA803881   AA804006   AA816826   AA820225   AA820544   AA820811   AA820894   AA821129   AA821156   AA821159   AA821205   AA938848   AA940606   AA940858   AA940939   AA941272   AA941541   AA941553   AA942202   AA942504   AA949012   AA949306   AA949380   AA949450   AA950149   AA950201   AA950373   AA950823   AA951307   AA951309   AA951894   AA952127   AA952287   AA978407   AA978813   AA978890   AA979297   AA979301   AA979317   AA979537   AA979540   AA979661   AE014296 AAF47545   AF080130 AAD19340   AI061695   AI061957   AI062000   AI062296   AI063723   AI063995   AI064033   AI064150   AI064517   AI106784   AI107029   AI107233   AI107367   AI107432   AI107461   AI108013   AI108125   AI108198   AI108323   AI108799   AI108815   AI109078   AI110148   AI113587   AI113691   AI114189   AI124251   AI134256   AI134459   AI134525   AI134532   AI134849   AI135197   AI135220   AI135397   AI135438   AI135612   AI136000   AI238379   AI238534   AI238913   AI239216   AI257010   AI257260   AI257375   AI257412   AI257452   AI257454   AI258009   AI258066   AI258177   AI258577   AI258854   AI259095   AI259201   AI259601   AI259675   AI259691   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BI632775   BI632916   BI632998   BI633024   BI633047   BI633110   BI633283   BI633345   BI633428   BI633633   BI633639   BI633755   BI633763   BI633874   BI633910   BI633941   BI634013   BI634731   BI634860   BI634951   BI634975   BI635129   BI635229   BI635238   BI635252   BI635307   BI635396   BI635470   BI635717   BI635737   BI635795   BI635853   BI635935   BI635959   BI635988   BI636050   BI636069   BI636093   BI636166   BI636176   BI636210   BI636218   BI636261   BI636296   BI636376   BI636519   BI636587   BI636703   BI636719   BI636817   BI636907   BI636980   BI637003   BI637086   BI637112   BI637315   BI637331   BI637337   BI637423   BI637576   BI637588   BI637591   BI637669   BI637691   BI637738   BI637739   BI637747   BI637936   BI637941   BI638137   BI638164   BI638247   BI638303   BI638339   BI638393   BI638504   BI638510   BI638527   BI638609   BI638694   BI638744   BI639014   BI639082   BI639137   BI639162   BI639350   BI639512   BI639631   BI639637   BI639892   BI640397   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CK605213   CK657304   CK657572   CK657630   CK657848   CK657941   CK658379   CK658512   CK658606   CK658717   CK658753   CK659318   CK659460   CK659669   CK660055   CK660262   CK660514   CK660554   CK660933   CK660996   CK661182   CK661357   CK662208   CO153101   CO153636   CO154899   CO154934   CO155453   CO155608   CO156016   CO156838   CO156892   CO156951   CO156993   CO157058   CO181957   CO184348   CO187306   CO191627   CO193634   CO195267   CO272437   CO298839   CO303695   CO320339   CO326890   CO332645   CO335989   CO336123   CO336483   CO336535   CO336813   CO336971   CO336988   CO337458   CO338398   CO338430   CO338587   DQ450529 ABE27283   EC052775   EC053569   EC056837   EC069253   EC069659   EC070330   EC070599   EC195063   EC206637   EC239759   EC249761   EC253151   EC261277   EC261456   EC261497   EC261548   EC261964   EC262291   EC262576   EC263085   EC263104   EC263622   EC263931   EC265144   EC265752   EC265850   EC265953   EC266588   EC266876   EC267130   EC267135   EC267434   EC267491   EC267662   EL870749   EL870818   EL870901   EL870971   EL871731   EL872554   EL876800   EL876960   EL878160   EL878401   EL882356   EL882857   EL883967   ES688494   ES689331   ES693430   EV576434   EV577807   EV578053   EV578345   EV578920   EV579013   EV579286   EV579584   EV580296   EV580431   EV581110   EV581164   EV581312   EV581400   EV581708   EV581756   EV582247   EV584250   EV584870   EV584880   EV585543   EV586013   EV586247   EV586283   EV586305   EV586632   EV587415   EV587587   EV587890   EV588039   EV588150   EV588215   EV588343   EV588490   EV588588   EV588675   EV588845   EV589279   EV589436   EV589495   EV589616   EV589663   EV590042   EV590192   EV590663   EV590770   EV590921   EV591194   EV591210   EV591518   EV591699   EV591892   EV592066   EV592676   EV592708   EV593477   EV593703   EV594367   EV595426   EV596699   EV597250   EV597314   EV598165   EV598806   EV599589   EV599642   EV600029   EV600130   GH754149   GH789975   GH796266   GH810746   GH820792   GH867782   GH924319
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O97118 Q5BHZ4 Q8SX05 Q9W0A8 Q0ZHI2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0026372    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0026372 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0026372 expression level Developmental Stage   Expression Level embryo 00-02hr    142297 embryo 02-04hr    212901 embryo 04-06hr    202278 embryo 06-08hr    214610 embryo 08-10hr    221355 embryo 10-12hr    241134 embryo 12-14hr    167693 embryo 14-16hr    209205 embryo 16-18hr    189226 embryo 18-20hr    243356 embryo 20-22hr    199533 embryo 22-24hr    185121 larva L1    261030 larva L2    220035 larva L3 12hr old    178252 larva L3 puffstage 1-2    138910 larva L3 puffstage 3-6    134961 larva L3 puffstage 7-9    137209 white prepupae new    119291 white prepupae 12hr    111097 white prepupae 24hr    115626 pupae 2d postWPP    110813 pupae 3d postWPP    91905 pupae 4d postWPP    102547 adult male 01day    75549 adult male 05day    74918 adult male 30day    86243 adult female 01day    171355 adult female 05day    154394 adult female 30day    169652 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (142297) embryo 02-04hr  (212901) embryo 04-06hr  (202278) embryo 06-08hr  (214610) embryo 08-10hr  (221355) embryo 10-12hr  (241134) embryo 12-14hr  (167693) embryo 14-16hr  (209205) embryo 16-18hr  (189226) embryo 18-20hr  (243356) embryo 20-22hr  (199533) embryo 22-24hr  (185121) larva L1  (261030) larva L2  (220035) larva L3 12hr old  (178252) larva L3 puffstage 1-2  (138910) larva L3 puffstage 3-6  (134961) larva L3 puffstage 7-9  (137209) white prepupae new  (119291) white prepupae 12hr  (111097) white prepupae 24hr  (115626) pupae 2d postWPP  (110813) pupae 3d postWPP  (91905) pupae 4d postWPP  (102547) adult male 01day  (75549) adult male 05day  (74918) adult male 30day  (86243) adult female 01day  (171355) adult female 05day  (154394) adult female 30day  (169652) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (142297) embryo 02-04hr  (212901) embryo 04-06hr  (202278) embryo 06-08hr  (214610) embryo 08-10hr  (221355) embryo 10-12hr  (241134) embryo 12-14hr  (167693) embryo 14-16hr  (209205) embryo 16-18hr  (189226) embryo 18-20hr  (243356) embryo 20-22hr  (199533) embryo 22-24hr  (185121) larva L1  (261030) larva L2  (220035) larva L3 12hr old  (178252) larva L3 puffstage 1-2  (138910) larva L3 puffstage 3-6  (134961) larva L3 puffstage 7-9  (137209) white prepupae new  (119291) white prepupae 12hr  (111097) white prepupae 24hr  (115626) pupae 2d postWPP  (110813) pupae 3d postWPP  (91905) pupae 4d postWPP  (102547) adult male 01day  (75549) adult male 05day  (74918) adult male 30day  (86243) adult female 01day  (171355) adult female 05day  (154394) adult female 30day  (169652) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (142297) embryo 02-04hr  (212901) embryo 04-06hr  (202278) embryo 06-08hr  (214610) embryo 08-10hr  (221355) embryo 10-12hr  (241134) embryo 12-14hr  (167693) embryo 14-16hr  (209205) embryo 16-18hr  (189226) embryo 18-20hr  (243356) embryo 20-22hr  (199533) embryo 22-24hr  (185121) larva L1  (261030) larva L2  (220035) larva L3 12hr old  (178252) larva L3 puffstage 1-2  (138910) larva L3 puffstage 3-6  (134961) larva L3 puffstage 7-9  (137209) white prepupae new  (119291) white prepupae 12hr  (111097) white prepupae 24hr  (115626) pupae 2d postWPP  (110813) pupae 3d postWPP  (91905) pupae 4d postWPP  (102547) adult male 01day  (75549) adult male 05day  (74918) adult male 30day  (86243) adult female 01day  (171355) adult female 05day  (154394) adult female 30day  (169652) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    142297 embryo 02-04hr    212901 embryo 04-06hr    202278 embryo 06-08hr    214610 embryo 08-10hr    221355 embryo 10-12hr    241134 embryo 12-14hr    167693 embryo 14-16hr    209205 embryo 16-18hr    189226 embryo 18-20hr    243356 embryo 20-22hr    199533 embryo 22-24hr    185121 larva L1    261030 larva L2    220035 larva L3 12hr old    178252 larva L3 puffstage 1-2    138910 larva L3 puffstage 3-6    134961 larva L3 puffstage 7-9    137209 white prepupae new    119291 white prepupae 12hr    111097 white prepupae 24hr    115626 pupae 2d postWPP    110813 pupae 3d postWPP    91905 pupae 4d postWPP    102547 adult male 01day    75549 adult male 05day    74918 adult male 30day    86243 adult female 01day    171355 adult female 05day    154394 adult female 30day    169652 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0026372 expression level Developmental Stage   Expression Level embryo 00-02hr    142297 embryo 02-04hr    212901 embryo 04-06hr    202278 embryo 06-08hr    214610 embryo 08-10hr    221355 embryo 10-12hr    241134 embryo 12-14hr    167693 embryo 14-16hr    209205 embryo 16-18hr    189226 embryo 18-20hr    243356 embryo 20-22hr    199533 embryo 22-24hr    185121 larva L1    261030 larva L2    220035 larva L3 12hr old    178252 larva L3 puffstage 1-2    138910 larva L3 puffstage 3-6    134961 larva L3 puffstage 7-9    137209 white prepupae new    119291 white prepupae 12hr    111097 white prepupae 24hr    115626 pupae 2d postWPP    110813 pupae 3d postWPP    91905 pupae 4d postWPP    102547 adult male 01day    75549 adult male 05day    74918 adult male 30day    86243 adult female 01day    171355 adult female 05day    154394 adult female 30day    169652 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (142297) embryo 02-04hr  (212901) embryo 04-06hr  (202278) embryo 06-08hr  (214610) embryo 08-10hr  (221355) embryo 10-12hr  (241134) embryo 12-14hr  (167693) embryo 14-16hr  (209205) embryo 16-18hr  (189226) embryo 18-20hr  (243356) embryo 20-22hr  (199533) embryo 22-24hr  (185121) larva L1  (261030) larva L2  (220035) larva L3 12hr old  (178252) larva L3 puffstage 1-2  (138910) larva L3 puffstage 3-6  (134961) larva L3 puffstage 7-9  (137209) white prepupae new  (119291) white prepupae 12hr  (111097) white prepupae 24hr  (115626) pupae 2d postWPP  (110813) pupae 3d postWPP  (91905) pupae 4d postWPP  (102547) adult male 01day  (75549) adult male 05day  (74918) adult male 30day  (86243) adult female 01day  (171355) adult female 05day  (154394) adult female 30day  (169652) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (142297) embryo 02-04hr  (212901) embryo 04-06hr  (202278) embryo 06-08hr  (214610) embryo 08-10hr  (221355) embryo 10-12hr  (241134) embryo 12-14hr  (167693) embryo 14-16hr  (209205) embryo 16-18hr  (189226) embryo 18-20hr  (243356) embryo 20-22hr  (199533) embryo 22-24hr  (185121) larva L1  (261030) larva L2  (220035) larva L3 12hr old  (178252) larva L3 puffstage 1-2  (138910) larva L3 puffstage 3-6  (134961) larva L3 puffstage 7-9  (137209) white prepupae new  (119291) white prepupae 12hr  (111097) white prepupae 24hr  (115626) pupae 2d postWPP  (110813) pupae 3d postWPP  (91905) pupae 4d postWPP  (102547) adult male 01day  (75549) adult male 05day  (74918) adult male 30day  (86243) adult female 01day  (171355) adult female 05day  (154394) adult female 30day  (169652) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (142297) embryo 02-04hr  (212901) embryo 04-06hr  (202278) embryo 06-08hr  (214610) embryo 08-10hr  (221355) embryo 10-12hr  (241134) embryo 12-14hr  (167693) embryo 14-16hr  (209205) embryo 16-18hr  (189226) embryo 18-20hr  (243356) embryo 20-22hr  (199533) embryo 22-24hr  (185121) larva L1  (261030) larva L2  (220035) larva L3 12hr old  (178252) larva L3 puffstage 1-2  (138910) larva L3 puffstage 3-6  (134961) larva L3 puffstage 7-9  (137209) white prepupae new  (119291) white prepupae 12hr  (111097) white prepupae 24hr  (115626) pupae 2d postWPP  (110813) pupae 3d postWPP  (91905) pupae 4d postWPP  (102547) adult male 01day  (75549) adult male 05day  (74918) adult male 30day  (86243) adult female 01day  (171355) adult female 05day  (154394) adult female 30day  (169652) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    142297 embryo 02-04hr    212901 embryo 04-06hr    202278 embryo 06-08hr    214610 embryo 08-10hr    221355 embryo 10-12hr    241134 embryo 12-14hr    167693 embryo 14-16hr    209205 embryo 16-18hr    189226 embryo 18-20hr    243356 embryo 20-22hr    199533 embryo 22-24hr    185121 larva L1    261030 larva L2    220035 larva L3 12hr old    178252 larva L3 puffstage 1-2    138910 larva L3 puffstage 3-6    134961 larva L3 puffstage 7-9    137209 white prepupae new    119291 white prepupae 12hr    111097 white prepupae 24hr    115626 pupae 2d postWPP    110813 pupae 3d postWPP    91905 pupae 4d postWPP    102547 adult male 01day    75549 adult male 05day    74918 adult male 30day    86243 adult female 01day    171355 adult female 05day    154394 adult female 30day    169652 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0026372    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0026372 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0026372 expression level Tissue   Expression Level Larval Central Nervous System    2604.45 Larval Midgut    4326 Larval Hindgut    4017.6 Larval Malpighian Tubules    4034.5 Larval Fat Body    6923 Larval Salivary Gland    7317.7 Larval Trachea    5859.65 Larval Carcass    4493.325 Adult Head    4388.7 Adult Eye    5285.675 Adult Brain    2961.5 Adult Thoracic-Abdominal Ganglion    3942.3 Adult Crop    5530 Adult Midgut    4963 Adult Hindgut    4702.3 Adult Malpighian Tubules    5493.8 Adult Fat Body    5293.1 Adult Salivary Gland    12204.1 Adult Heart    6288.05 Adult VirginFemale Spermatheca    5032.4 Adult InseminatedFemale Spermatheca    5292.4 Adult Ovary    3165.5 Adult Testis    1065.2 Adult Male Accessory Gland    8782.3 Adult Carcass    5287.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2604.45) Larval Midgut  (4326) Larval Hindgut  (4017.6) Larval Malpighian Tubules  (4034.5) Larval Fat Body  (6923) Larval Salivary Gland  (7317.7) Larval Trachea  (5859.65) Larval Carcass  (4493.325) Adult Head  (4388.7) Adult Eye  (5285.675) Adult Brain  (2961.5) Adult Thoracic-Abdominal Ganglion  (3942.3) Adult Crop  (5530) Adult Midgut  (4963) Adult Hindgut  (4702.3) Adult Malpighian Tubules  (5493.8) Adult Fat Body  (5293.1) Adult Salivary Gland  (12204.1) Adult Heart  (6288.05) Adult VirginFemale Spermatheca  (5032.4) Adult InseminatedFemale Spermatheca  (5292.4) Adult Ovary  (3165.5) Adult Testis  (1065.2) Adult Male Accessory Gland  (8782.3) Adult Carcass  (5287.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2604.45) Larval Midgut  (4326) Larval Hindgut  (4017.6) Larval Malpighian Tubules  (4034.5) Larval Fat Body  (6923) Larval Salivary Gland  (7317.7) Larval Trachea  (5859.65) Larval Carcass  (4493.325) Adult Head  (4388.7) Adult Eye  (5285.675) Adult Brain  (2961.5) Adult Thoracic-Abdominal Ganglion  (3942.3) Adult Crop  (5530) Adult Midgut  (4963) Adult Hindgut  (4702.3) Adult Malpighian Tubules  (5493.8) Adult Fat Body  (5293.1) Adult Salivary Gland  (12204.1) Adult Heart  (6288.05) Adult VirginFemale Spermatheca  (5032.4) Adult InseminatedFemale Spermatheca  (5292.4) Adult Ovary  (3165.5) Adult Testis  1065.2 Adult Male Accessory Gland  (8782.3) Adult Carcass  (5287.9) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2604.45 Larval Midgut    4326 Larval Hindgut    4017.6 Larval Malpighian Tubules    4034.5 Larval Fat Body    6923 Larval Salivary Gland    7317.7 Larval Trachea    5859.65 Larval Carcass    4493.325 Adult Head    4388.7 Adult Eye    5285.675 Adult Brain    2961.5 Adult Thoracic-Abdominal Ganglion    3942.3 Adult Crop    5530 Adult Midgut    4963 Adult Hindgut    4702.3 Adult Malpighian Tubules    5493.8 Adult Fat Body    5293.1 Adult Salivary Gland    12204.1 Adult Heart    6288.05 Adult VirginFemale Spermatheca    5032.4 Adult InseminatedFemale Spermatheca    5292.4 Adult Ovary    3165.5 Adult Testis    1065.2 Adult Male Accessory Gland    8782.3 Adult Carcass    5287.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0026372 expression level Tissue   Expression Level Larval Central Nervous System    2604.45 Larval Midgut    4326 Larval Hindgut    4017.6 Larval Malpighian Tubules    4034.5 Larval Fat Body    6923 Larval Salivary Gland    7317.7 Larval Trachea    5859.65 Larval Carcass    4493.325 Adult Head    4388.7 Adult Eye    5285.675 Adult Brain    2961.5 Adult Thoracic-Abdominal Ganglion    3942.3 Adult Crop    5530 Adult Midgut    4963 Adult Hindgut    4702.3 Adult Malpighian Tubules    5493.8 Adult Fat Body    5293.1 Adult Salivary Gland    12204.1 Adult Heart    6288.05 Adult VirginFemale Spermatheca    5032.4 Adult InseminatedFemale Spermatheca    5292.4 Adult Ovary    3165.5 Adult Testis    1065.2 Adult Male Accessory Gland    8782.3 Adult Carcass    5287.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2604.45) Larval Midgut  (4326) Larval Hindgut  (4017.6) Larval Malpighian Tubules  (4034.5) Larval Fat Body  (6923) Larval Salivary Gland  (7317.7) Larval Trachea  (5859.65) Larval Carcass  (4493.325) Adult Head  (4388.7) Adult Eye  (5285.675) Adult Brain  (2961.5) Adult Thoracic-Abdominal Ganglion  (3942.3) Adult Crop  (5530) Adult Midgut  (4963) Adult Hindgut  (4702.3) Adult Malpighian Tubules  (5493.8) Adult Fat Body  (5293.1) Adult Salivary Gland  (12204.1) Adult Heart  (6288.05) Adult VirginFemale Spermatheca  (5032.4) Adult InseminatedFemale Spermatheca  (5292.4) Adult Ovary  (3165.5) Adult Testis  (1065.2) Adult Male Accessory Gland  (8782.3) Adult Carcass  (5287.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2604.45) Larval Midgut  (4326) Larval Hindgut  (4017.6) Larval Malpighian Tubules  (4034.5) Larval Fat Body  (6923) Larval Salivary Gland  (7317.7) Larval Trachea  (5859.65) Larval Carcass  (4493.325) Adult Head  (4388.7) Adult Eye  (5285.675) Adult Brain  (2961.5) Adult Thoracic-Abdominal Ganglion  (3942.3) Adult Crop  (5530) Adult Midgut  (4963) Adult Hindgut  (4702.3) Adult Malpighian Tubules  (5493.8) Adult Fat Body  (5293.1) Adult Salivary Gland  (12204.1) Adult Heart  (6288.05) Adult VirginFemale Spermatheca  (5032.4) Adult InseminatedFemale Spermatheca  (5292.4) Adult Ovary  (3165.5) Adult Testis  1065.2 Adult Male Accessory Gland  (8782.3) Adult Carcass  (5287.9) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2604.45 Larval Midgut    4326 Larval Hindgut    4017.6 Larval Malpighian Tubules    4034.5 Larval Fat Body    6923 Larval Salivary Gland    7317.7 Larval Trachea    5859.65 Larval Carcass    4493.325 Adult Head    4388.7 Adult Eye    5285.675 Adult Brain    2961.5 Adult Thoracic-Abdominal Ganglion    3942.3 Adult Crop    5530 Adult Midgut    4963 Adult Hindgut    4702.3 Adult Malpighian Tubules    5493.8 Adult Fat Body    5293.1 Adult Salivary Gland    12204.1 Adult Heart    6288.05 Adult VirginFemale Spermatheca    5032.4 Adult InseminatedFemale Spermatheca    5292.4 Adult Ovary    3165.5 Adult Testis    1065.2 Adult Male Accessory Gland    8782.3 Adult Carcass    5287.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4388.7   NA  Eye    5285.675   NA  Brain    2961.5   2604.45  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3942.3   NA  Crop    5530   4326  Midgut    4963   4017.6  Hindgut    4702.3   4034.5  Malpighian Tubules    5493.8   6923  Fat Body    5293.1   7317.7  Salivary Gland    12204.1   NA  Heart    6288.05   5859.65  Trachea    NA   NA  VirginFemale Spermatheca    5032.4   NA  InseminatedFemale Spermatheca    5292.4   NA  Ovary    3165.5   NA  Testis    1065.2   NA  Male Accessory Gland    8782.3   4493.325  Carcass    5287.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_22
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026372 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7977-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable RpL23Af02629 Sterility Allele fertile RpL23Af02629 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of RpL23A Class Mutagen Stocks Known lesion RpL23Af02629 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpL23A Class Mutagen Stocks Known lesion RpL23AKK107646 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpL23AGD12339 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12339} NA P{KK107646} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}RpL23Af02629 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
centrosome duplication inferred from mutant phenotype (Müller et al., 2010)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006) ribosome inferred from direct assay (Alonso and Santaren, 2006)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
nucleotide binding inferred from electronic annotation with InterPro:IPR012677 (FlyBase Curators et al., 2004-) RNA binding inferred from electronic annotation with InterPro:IPR001014 (FlyBase Curators et al., 2004-) structural constituent of ribosome inferred from sequence or structural similarity (Hursh, 1995.7.5) inferred from sequence or structural similarity with Saccharomyces RPL25 (FlyBase, 1992-) non-traceable author statement (Koyama, 1998.7.24)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity (Hursh, 1995.7.5) inferred from sequence or structural similarity with Saccharomyces RPL25 (FlyBase, 1992-) non-traceable author statement (Koyama, 1998.7.24)
Cellular Component
CV term Evidence References
cytosolic large ribosomal subunit inferred from sequence or structural similarity (Hursh, 1995.7.5) inferred from sequence or structural similarity with Saccharomyces RPL25 (FlyBase, 1992-) non-traceable author statement (Koyama, 1998.7.24)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpL23A allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63742 DroID - A comprehensive database of gene and protein interactions. • FBgn0026372 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38208
Orthologs
Genome-wide drosophilid orthologs	Dgri\GH15515 Dmoj\GI16793 Dper\GL12432 Dpse\GA20736 Dsec\GM14186 Dsim\GD13453 Dvir\GJ12535 Dwil\GK17068 Dyak\RpL23A
Curated drosophilid orthologs	Dpse\GA20736   Dsim\RpL23A (Swanson et al., 2001) Dyak\RpL23A
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP006037-PA Anopheles gambiae (mosquito) XP_393135.2 Apis mellifera (honey bee) XP_001942614.1 Acyrthosiphon pisum (pea aphid) At3g55280.1 Arabidopsis thaliana (wall cress) 24589 Batrachochytrium dendrobatidis (chytrid fungus) 121811 Branchiostoma floridae (lancelet) 128223 Branchiostoma floridae (lancelet) XP_001892438.1 Brugia malayi (roundworm nematode) ENSBTAP00000030092 Bos taurus (bovine) ENSBTAP00000037041 Bos taurus (bovine) ENSBTAP00000042806 Bos taurus (bovine) ENSBTAP00000050293 Bos taurus (bovine) ENSBTAP00000051846 Bos taurus (bovine) CBP03565 Caenorhabditis briggsae (nematode) CE02777 Caenorhabditis elegans (worm) ENSCAFP00000027708 Canis familiaris (dog) ENSCINP00000020870 Ciona intestinalis (sea squirt) JA13564 Caenorhabditis japonica (nematode) CMK273C Cyanidioschyzon merolae (red alga) cn03699 Cryptococcus neoformans (yeast-like fungus) cgd8_650 Cryptosporidium parvum (protozoan parasite) CPIJ000279 Culex pipens (mosquito) ENSCPOP00000001312 Cavia porcellus (guinea pig) 174711 Chlamidomonas reinhardtii (green alga) RP39566 Caenorhabditis remanei (nematode) 158372 Capitella spl (polychaete worm) DDB0230149 Dictyostelium discoideum (amoeba) 314559 Daphnia pulex (daphnia) ENSDARP00000006624 Danio rerio (zebra fish) ENSECAP00000001545 Equus caballus (horse) ENSECAP00000006994 Equus caballus (horse) ENSGACP00000027282 Gymnopilus aculeatus (mushroom) ENSGALP00000006308 Gallus gallus (chicken) 101069 Hypsipyla robusta (cedar shoot borer) ENSP00000378396 Homo sapiens (human) ISCW024803-PA Ixodes scapularis (deer tick) 127930 Lottia gigantea (owl limpet) LmjF06.0570 Leishmania major (virus) LmjF06.0580 Leishmania major (virus) ENSMODP00000020505 Monodelphis domestica (gray opossum) ENSMMUP00000009522 Macaca mulatta (rhesus monkey) ENSMMUP00000010107 Macaca mulatta (rhesus monkey) ENSMMUP00000034588 Macaca mulatta (rhesus monkey) ENSMMUP00000035786 Macaca mulatta (rhesus monkey) ENSMMUP00000039495 Macaca mulatta (rhesus monkey) ENSMUSP00000078397 Mus musculus (house mouse) ENSMUSP00000093719 Mus musculus (house mouse) ENSMUSP00000099541 Mus musculus (house mouse) ENSMUSP00000100528 Mus musculus (house mouse) 160446 Nematostella vectensis (starlet anemone) XP_001604487.1 Nasonia vitripennis (wasp) ENSOANP00000015173 Ornithorynchus anatinus (platypus) ENSORLP00000006953 Oryzias latipes (japanese killifish) LOC_Os04g42270.1 Oryza sativa (asian rice) 26182 Ostreococcus tauri (green alga) PF13_0132 Plasmodium falciparum (protozoal parasite) PHUM008891-PA Pediculus humanus (human body louse) PP04054 Pristionchus pacificus (nematode) 190449 Physcomitrella patens (moss) 208348 Physcomitrella patens (moss) ENSPPYP00000009116 Pongo pygmaeus (orangutan) 79226 Phytophthora ramorum (sudden oak death pathogen) 95330 Phytophthora ramorum (sudden oak death pathogen) 822509 Populus trichocarpa (black cottonwood) ENSPTRP00000058561 Pan troglodytes (chimpanzee) PVX_116700 Plasmodium vivax (protozoal parasite) ENSRNOP00000036391 Rattus norvegicus (norway rat) ENSRNOP00000043004 Rattus norvegicus (norway rat) ENSRNOP00000049652 Rattus norvegicus (norway rat) 146683 Sorghum bicolor (sorghum) Smp_003410 Schistosoma mansoni (trematode parasite) SPBC106.18 Schizosaccharomyces pombe (fission yeast) XP_792948.2 Strongylocentrotus purpuratus (purple sea urchin) 36440 Trichoplax adhaerens (metazoa) TA17715 Theileria annulata (apicomplexan parasite) XP_967229.1 Tribolium castaneum (red flour beetle) Tc00.1047053509151.140 Trypanosoma cruzi (parasitic trypanosome) 6363 Thalassiosira pseudonana (marine diatom) ENSTRUP00000043745 Takifugu rubripes (pufferfish Takifugu) 3698.m00088 Tetrahymena thermophila (ciliate protozoa) 83472.m00427 Trichomonas vaginalis (parasitic flagellated protozoan) 85746.m00167 Trichomonas vaginalis (parasitic flagellated protozoan) 86319.m00318 Trichomonas vaginalis (parasitic flagellated protozoan) 87835.m00286 Trichomonas vaginalis (parasitic flagellated protozoan) 95287.m00218 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000055350 Xenopus tropicalis (frog) YALI0F25531g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15360 NV13579 LH22940 ISCW024803 FBgn0068075 FBgn0219067 FBgn0199775 FBgn0185165 FBgn0169112 JGI_V11_314559 FBgn0080727 FBgn0150038 FBgn0139540 FBgn0122987 CPIJ000279 BGIBMGA006835 ACYPI007628 GB12508 AGAP006037 AAEL017516 PHUM361800 GLEAN_12708
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	18568 w1118; PBac{WH}RpL23Af02629
Harvard	- PBac{WH}RpL23Af02629
VDRC	v101337 P{KK107646}VIE-260B
Genomic Clones ( 2 )
	BACR14O14 BACR17K18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 1220 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM06171 IP17216 RH35480
Other clones	FI01658 yak-ad_RpL23a yak-em_RpL23a
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT07757 AT08883 AT11394 AT13712 AT14108 AT27868 AT29431 AT31171 GH05936 GH06314 GH08106 GH10904 GH11665 GH13106 GH13432 GH13991 GH15051 GH15795 GH16239 GH17004 GH17363 GH18110 GH20039 GH20446 GH21633 GH21831 GH21925 GH22877 GH23024 GH23090 GH24231 GH24250 GH24690 GH26787 GH27173 GH27638 GH27830 GH28805 GM03371 GM04092 GM07866 GM14415 GM14867 GM15391 GM15755 GM16496 GM19681 GM19691 GM20269 GM21029 GM22626 GM22646 GM28578 GM29169 GM29424 GM29445 GM32119 GM32151 GM32794 LD04258 LD12678 LD13791 LD18153 LD21856 LD23283 LD24332 LD24713 LD25278 LD29462 LD30154 LD30963 LD33077 LD33680 LD35064 LD35144 LD37001 LD37606 LD37639 LD37691 LD38012 LD38022 LD38912 LD39412 LD40722 LD41057 LD41840 LD42017 LD43084 LD43418 LD44434 LD45610 LD46182 LD46717 LD46801 LD46889 LD47126 LD47375 LD48083 LP01309 LP02150 LP03314 LP05208 LP05571 LP05717 LP05769 LP05826 LP06509 LP06565 LP08924 LP09522 LP10026 LP10029 LP10684 LP11535 LP13893 LP13980 LP13985 LP15475 LP15888 LP16996 LP18285 LP19142 LP19196 LP19907 LP20394 LP20806 LP22246 LP24465 RE43789 RE47216 SD01154 SD01392 SD03154 SD04504 SD04589 SD04695 SD04765 SD04812 SD05852 SD10523 SD11142 SD11294 SD11310 SD11523 SD12009 SD13495 SD13590 SD14125 SD14444 SD14505 SD14841 SD15495 SD15633 SD15920 SD16167 SD16187 SD17157 SD17280 SD17541 SD17615 SD17661 SD17756 SD17773 SD17823 SD18223 SD18504 SD18524 SD18844 SD19001 SD19314 SD19320 SD19622 SD20127 SD20604 SD20812 SD20832 SD21114 SD22264 SD22595 SD23539 SD25593 SD26087 SD26159 SD26448 SD26642 SD27335 SD27415 SD27512
Other clones	159960 214503.20 277003 522056 524231 524264 524870 525046 525727 527058 528293 533433 533503 533541 533610 556875 557029 557900 557959 562032 562046 569050 571360 571401 572820 AT05576 AT07843 AT08013 AT19751 AT22019 AT28273 AT31351 AT31770 CK01.32C.H5 CK01.40B.E10 CK01.45A.D1 CK01.65B.G12 CK01.92B.E7 CK01.98C.H11 CK01.117C.C3 Dmel_dig_005241_0593_1373 Dmel_dig_005820_0666_0591 Dmel_dig_007512_0640_3522 Dmel_dig_007854_0597_0608 Dmel_dig_009810_0639_0435 Dmel_dig_010153_0583_3354 Dmel_dig_010163_0710_2426 Dmel_dig_010201_0638_1919 Dmel_dig_011872_0595_0966 Dmel_dig_012921_0707_2822 Dmel_dig_013689_0672_3671 Dmel_dig_014373_0639_2036 Dmel_dig_016654_0593_1893 Dmel_dig_016963_0586_2899 Dmel_dig_018019_0682_1548 Dmel_dig_018166_0594_3596 Dmel_dig_018396_0615_0992 Dmel_dig_018536_0660_2548 Dmel_dig_019449_0641_2558 Dmel_dig_019609_0662_1213 Dmel_dig_019905_0597_0710 Dmel_dig_020483_0604_2848 Dmel_neb_005498_0142_0675 Dmel_neb_006514_0079_1606 Dmel_neb_007853_0566_2482 Dmel_neb_007859_0362_3601 Dmel_neb_007973_0096_2235 Dmel_neb_008223_0395_3638 Dmel_neb_008862_0380_2521 Dmel_neb_009764_0695_3707 Dmel_neb_009780_0169_0770 Dmel_neb_010120_0870_1829 Dmel_neb_010220_0429_1948 Dmel_neb_010269_0155_1535 Dmel_neb_010628_0327_1025 Dmel_neb_010659_0396_1087 Dmel_neb_010709_0165_3193 Dmel_neb_011090_0328_3294 Dmel_neb_011345_0398_0550 Dmel_neb_011359_0687_1419 Dmel_neb_011560_0950_1104 Dmel_neb_011662_0436_2792 Dmel_neb_011789_0150_0792 Dmel_neb_011804_0128_2818 Dmel_neb_012075_0141_0622 Dmel_neb_012336_0081_3005 Dmel_neb_012433_0389_3273 Dmel_neb_012550_0830_1074 Dmel_neb_012693_0892_1531 Dmel_neb_012726_0082_2010 Dmel_neb_012897_0450_3703 Dmel_neb_012978_0083_2323 Dmel_neb_013167_0611_2935 Dmel_neb_013366_0677_1445 Dmel_neb_013579_0943_3455 Dmel_neb_013760_0078_2658 Dmel_neb_013763_0634_0696 Dmel_neb_013917_0170_3532 Dmel_neb_014183_0450_1084 Dmel_neb_014265_0904_2787 Dmel_neb_014332_0874_2597 Dmel_neb_014515_0153_1678 Dmel_neb_014947_0339_1122 Dmel_neb_015060_0375_2312 Dmel_neb_015305_0334_1145 Dmel_neb_015359_0935_3230 Dmel_neb_015439_0580_3514 Dmel_neb_015972_0824_3338 EC17557 EC27950 EC31551 EC36525 EC39955 EC052775 EC053569 EK027931 EK107205 EK173949 EK242552 EK284207 EK304132 EN01261 EN02502 EN05011 EN05047 EN06056 EN06420 EN07212 EN09415 EN09518 EN09636 EN09722 EN09845 EN11616 EN11863 EN12626 EN12727 EN13304 EN13562 EN13619 EN14606 EN16717 EN16763 EN17134 EP04921 EST63 FGH108B03 FGH113H05 FGH123D01 FGM001E06 FGM001E09 FGM002A06 FGM002C05 FGM002H07 FGM004A04 FGM208A08 FGM210E03 FGM219F02 FGM221G02 FGM225A12 FGM233A04 FGM234H09 FGM237F05 FGM238C01 FGM313H01 GH01035 GH01452 GH03688 GH04177 GH04237 GH04280 GH04423 GH04966 GH05114 GH05156 GH06002 GH06567 GH06872 GH06972 GH07138 GH07594 GH08072 GH09633 GH09942 GH10121 GH11933 GH12013 GH12020 GH12417 GH12855 GH12881 GH13211 GH14414 GH14590 GH15569 GH15588 GH16830 GH16992 GH17343 GH17418 GH17614 GH18339 GH18420 GH18446 GH18482 GH18626 GH19494 GH19641 GH21833 GH22677 GH22910 GH25373 GH25374 GH26518 GH26619 GH27604 GH27677 GH28393 GM01018 GM01023 GM01693 GM01718 GM01928 GM01977 GM02333 GM02736 GM03150 GM03158 GM03289 GM03585 GM03757 GM03856 GM04143 GM04194 GM04401 GM04420 GM04625 GM04920 GM04994 GM05869 GM06409 GM06617 GM06641 GM06663 GM06664 GM06910 GM07916 GM08444 GM08469 GM08753 GM08834 GM09234 GM09820 GM10310 GM10391 GM10716 GM12510 GM12939 GM12968 GM13114 GM13143 GM13552 GM13568 GM13577 GM13927 GM14022 GM14178 GM14210 GM14449 GM14515 GM14652 GM14725 GM14738 GM15128 GM15582 GM15789 GM16761 GM16852 GM17176 GM17238 GM17258 GM17532 GM18665 GM18853 GM19267 GM19635 GM22466 GM22972 GM23861 GM24803 GM24805 GM25029 GM25260 GM25340 GM25522 GM26301 GM26664 GM26722 GM27081 GM27461 GM27528 GM27639 GM28071 GM28133 GM29060 GM29134 GM29368 GM29427 GM29587 GM29711 GM29919 GM30167 GM30852 GM32075 GM32139 GM32223 HL05653 HL08131 HL08188 IP02818 IP02918 IP03018 IP03118 IP03788 IP04458 IP06718 IP06882 IP08056 IP08256 IP12131 IP12542 IP13606 LD03043 LD04079 LD04490 LD05446 LD06107 LD06312 LD06788 LD10856 LD11382 LD16680 LD20801 LD21106 LD21449 LD23139 LD23727 LD24825 LD25325 LD25726 LD25745 LD26278 LD26756 LD27744 LD28148 LD28253 LD28908 LD29195 LD29410 LD30071 LD30504 LD31710 LD31712 LD32781 LD32981 LD33687 LD33774 LD33810 LD34153 LD34156 LD34371 LD35612 LD35614 LD36803 LD37540 LD37836 LD38833 LD40402 LD41283 LD41847 LD42316 LD42491 LD43405 LD43504 LD45639 LD46843 LP01156 LP01805 LP02425 LP02559 LP03053 LP03144 LP03162 LP04309 LP04869 LP04963 LP05829 LP07227 LP07958 LP08090 LP08111 LP08410 LP08841 LP09257 LP09563 LP09896 LP10141 LP10552 LP11511 LP11740 LP11968 LP12404 LP12909 LP13691 LP15262 LP15660 LP15973 LP17235 LP17586 LP18679 LP20037 LP23490 LP23980 LP24088 RE01116 RE01141 RE01173 RE02015 RE02158 RE02956 RE03180 RE03389 RE03669 RE04285 RE04316 RE04936 RE05094 RE05541 RE05781 RE06568 RE06974 RE07424 RE07858 RE08917 RE09549 RE09761 RE10225 RE11331 RE11763 RE13745 RE14576 RE15904 RE16054 RE17591 RE18725 RE18825 RE19286 RE20651 RE20712 RE22026 RE22446 RE22891 RE24441 RE25693 RE27488 RE28626 RE29179 RE29386 RE31144 RE31311 RE33374 RE35251 RE36269 RE37708 RE38241 RE39902 RE41543 RE42254 RE44205 RE44237 RE46384 RE46450 RE46855 RE47025 RE51553 RE52065 RE52517 RE53418 RE53740 RE54072 RE54549 RE56248 RE57515 RE57579 RE58053 RE58067 RE58691 RE62174 RE62231 RE62257 RE63104 RE63278 RE63484 RE63966 RE64163 RE64341 RE64735 RE65008 RE65453 RE65537 RE65562 RE66770 RE67137 RE67344 RE67871 RE68159 RE68994 RE69803 RE70583 RE71012 RE71034 RE71079 RE71122 RE71869 RE74229 RE74420 RE74553 RE74648 RE74870 RE75043 RH01546 RH01809 RH01941 RH01945 RH02082 RH02647 RH03456 RH03613 RH03655 RH03672 RH03739 RH03979 RH04176 RH04259 RH05053 RH05117 RH05136 RH05561 RH05767 RH05810 RH06012 RH06080 RH06096 RH06243 RH06625 RH07041 RH07135 RH07211 RH07283 RH07303 RH07347 RH07448 RH07486 RH07608 RH07756 RH07884 RH08061 RH08102 RH08229 RH08238 RH08485 RH08531 RH08771 RH08776 RH09166 RH09556 RH09569 RH09645 RH09747 RH09966 RH10072 RH10738 RH10803 RH10885 RH10987 RH11318 RH11357 RH11358 RH12061 RH12080 RH12206 RH12759 RH13077 RH13094 RH13842 RH13855 RH14114 RH14511 RH14823 RH14887 RH15012 RH15420 RH15994 RH16328 RH16943 RH16953 RH17442 RH17466 RH17641 RH17644 RH18022 RH18375 RH19644 RH19720 RH19744 RH20019 RH21369 RH21438 RH21711 RH22069 RH22213 RH22481 RH23110 RH23363 RH23452 RH23646 RH23724 RH24185 RH24418 RH24582 RH24650 RH24852 RH25079 RH25463 RH25625 RH26335 RH26806 RH26869 RH26904 RH27021 RH27134 RH27330 RH27359 RH27452 RH27719 RH27723 RH27967 RH28114 RH28137 RH28317 RH28405 RH28443 RH28809 RH29695 RH29771 RH30037 RH30166 RH30210 RH30273 RH31047 RH31194 RH31553 RH32050 RH32447 RH33434 RH33932 RH34360 RH34393 RH34588 RH34728 RH34921 RH35041 RH35071 RH35233 RH35343 RH35803 RH35850 RH36013 RH36071 RH36206 RH36422 RH36544 RH36857 RH37815 RH37822 RH37946 RH38543 RH38949 RH39111 RH39535 RH39546 RH39686 RH39931 RH39963 RH40003 RH40103 RH40346 RH40568 RH40839 RH40855 RH41420 RH41507 RH41536 RH41756 RH41875 RH42133 RH42406 RH42740 RH42839 RH43195 RH43594 RH43642 RH44192 RH44764 RH44836 RH45034 RH45284 RH45420 RH45753 RH46882 RH47131 RH47261 RH47872 RH47931 RH48139 RH48284 RH48540 RH48621 RH48629 RH49664 RH49783 RH49930 RH50555 RH50632 RH51291 RH51419 RH51467 RH51560 RH51961 RH52095 RH52119 RH52203 RH52340 RH52585 RH52610 RH52629 RH52787 RH52903 RH53059 RH53153 RH53754 RH53978 RH53988 RH54292 RH54534 RH55085 RH55363 RH55781 RH55879 RH56004 RH56084 RH56303 RH56363 RH56451 RH56459 RH56621 RH56769 RH57290 RH57512 RH57545 RH57559 RH58102 RH58114 RH58687 RH59161 RH59337 RH59345 RH59409 RH59502 RH59517 RH59824 RH60205 RH60362 RH60541 RH60707 RH60975 RH61283 RH61409 RH61529 RH61545 RH61640 RH61681 RH61767 RH62024 RH62052 RH62203 RH62207 RH62229 RH62361 RH62565 RH62675 RH62987 RH63153 RH63420 RH63704 RH63861 RH63970 RH64909 RH65103 RH65142 RH65458 RH65495 RH65516 RH65923 RH66181 RH66326 RH66370 RH66575 RH66611 RH66850 RH67041 RH67332 RH67426 RH67593 RH67927 RH67955 RH68033 RH68193 RH68547 RH68637 RH68784 RH69192 RH69550 RH69780 RH69917 RH69983 RH70138 RH70278 RH70294 RH70355 RH70356 RH71102 RH71364 RH71527 RH71611 RH71654 RH71747 RH71772 RH71774 RH71782 RH71841 RH71872 RH71943 RH72185 RH72884 RH73144 RH73261 RH73275 RH73576 RH73629 RH73724 RH74091 RH74393 RH74628 RH74660 RH74676 RH74760 RP003098332 RP003191389 RP003237734 RP003241739 RP003345627 RP003473081 RP003571632 SD01304 SD01358 SD01696 SD02496 SD02760 SD02884 SD03037 SD03869 SD04618 SD04632 SD05007 SD05106 SD05695 SD05928 SD06582 SD06850 SD07007 SD07379 SD09003 SD09515 SD10006 SD10184 SD10725 SD10867 SD11042 SD11138 SD11277 SD11354 SD11369 SD11413 SD11701 SD11757 SD12048 SD12337 SD12356 SD12524 SD12592 SD12662 SD13060 SD13280 SD13333 SD13453 SD13515 SD13570 SD13685 SD13944 SD14065 SD14212 SD14612 SD14704 SD14725 SD14740 SD15093 SD15161 SD15162 SD15318 SD15542 SD15701 SD15755 SD15775 SD15955 SD16050 SD16124 SD16375 SD16516 SD16528 SD16547 SD16614 SD16737 SD16835 SD17188 SD17373 SD17477 SD17508 SD17636 SD17832 SD17885 SD17932 SD18030 SD18321 SD18642 SD18752 SD18876 SD19032 SD19289 SD19439 SD19638 SD19641 SD19728 SD19750 SD19806 SD19807 SD19815 SD20112 SD20352 SD20384 SD20487 SD20556 SD20670 SD20806 SD20943 SD21049 SD21443 SD21531 SD21591 SD21638 SD21914 SD22102 SD22271 SD23240 SD23241 SD23435 SD23510 SD23587 SD23649 SD23652 SD24013 SD24524 SD24561 SD24578 SD24879 SD25008 SD25419 SD25526 SD25532 SD26462 SD26468 SD26577 SD26590 SD26818 SD26928 SD26977 SD27015 SD27094 SD27770 SD27777 SD27910 SD27920 SD28050 SD28108 SD28148 SD28241 UT01079 UT01159 UT01172 UT01340 UT01395 UT01459 UT01637 UT01645 UT01759 UUGC0159
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0026372 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38208
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: RpL23a anon-EST:fe2D1 (Bayraktaroglu, 2000.11.2) Source for merge of: RpL23A anon-EST:Liang-1.4 (Ashburner, 2004.6.30) Source for merge of: RpL23a RpL25 (Luschnig, 2003.6.11)
Additional comments	"RpL23A" likely corresponds to "M(3)62A". (Marygold et al., 2007) FlyBase curator comment: the insertion in the "e04143" Exelixis line (PBac{RB}RabX5e04143) was originally assigned to the RpL23A gene in FBrf0179797, resulting in the "RpL23Ae04143" (FBal0159876) allele. However, FBrf0184340 shows that the insertion is actually within RabX5. (Bloomington Drosophila Stock Center, 2004.11.6)
Other Comments
	Likely Minute gene. (Marygold et al., 2007) Deletions removing RpL23A but no other cytoplasmic ribosomal protein-encoding genes show Minute phenotypes. (Marygold et al., 2007) Identification: Protein that interacts with the AM domain of Parp protein. (Koyama et al., 1999)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079162 RefSeq (Proteins) • NP_523886 DDBJ / EMBL / GenBank • AA433249 AA695737 AA802706 AAD19340 AAF47545 AAM11274 AAX33578 ABE27283 AF080130 AI124251 AW941956 AY094921 BI566274 BT021430 DQ450529 Entrez Gene - A searchable database of RefSeq genes. • 38208 UniProtKB/TrEMBL • O97118 Q0ZHI2 Q5BHZ4 Q8SX05 Q9W0A8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L23/L25, conserved site (IPR001014) Ribosomal protein L23/L25, N-terminal (IPR005633) Nucleotide-binding, alpha-beta plait (IPR012677) Ribosomal protein L23/L15e (IPR012678) Ribosomal protein L25/L23 (IPR013025)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63742 DroID - A comprehensive database of gene and protein interactions. • FBgn0026372 DRSC - Results from RNAi screens. • FBgn0026372 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026372 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7977-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0026372 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38208 InParanoid A subset of ortholog calls from InParanoid. • AGAP006037-PA Anopheles gambiae (mosquito) XP_393135.2 Apis mellifera (honey bee) XP_001942614.1 Acyrthosiphon pisum (pea aphid) At3g55280.1 Arabidopsis thaliana (wall cress) 24589 Batrachochytrium dendrobatidis (chytrid fungus) 121811 Branchiostoma floridae (lancelet) 128223 Branchiostoma floridae (lancelet) XP_001892438.1 Brugia malayi (roundworm nematode) ENSBTAP00000030092 Bos taurus (bovine) ENSBTAP00000037041 Bos taurus (bovine) ENSBTAP00000042806 Bos taurus (bovine) ENSBTAP00000050293 Bos taurus (bovine) ENSBTAP00000051846 Bos taurus (bovine) CBP03565 Caenorhabditis briggsae (nematode) CE02777 Caenorhabditis elegans (worm) ENSCAFP00000027708 Canis familiaris (dog) ENSCINP00000020870 Ciona intestinalis (sea squirt) JA13564 Caenorhabditis japonica (nematode) CMK273C Cyanidioschyzon merolae (red alga) cn03699 Cryptococcus neoformans (yeast-like fungus) cgd8_650 Cryptosporidium parvum (protozoan parasite) CPIJ000279 Culex pipens (mosquito) ENSCPOP00000001312 Cavia porcellus (guinea pig) 174711 Chlamidomonas reinhardtii (green alga) RP39566 Caenorhabditis remanei (nematode) 158372 Capitella spl (polychaete worm) DDB0230149 Dictyostelium discoideum (amoeba) 314559 Daphnia pulex (daphnia) ENSDARP00000006624 Danio rerio (zebra fish) ENSECAP00000001545 Equus caballus (horse) ENSECAP00000006994 Equus caballus (horse) ENSGACP00000027282 Gymnopilus aculeatus (mushroom) ENSGALP00000006308 Gallus gallus (chicken) 101069 Hypsipyla robusta (cedar shoot borer) ENSP00000378396 Homo sapiens (human) ISCW024803-PA Ixodes scapularis (deer tick) 127930 Lottia gigantea (owl limpet) LmjF06.0570 Leishmania major (virus) LmjF06.0580 Leishmania major (virus) ENSMODP00000020505 Monodelphis domestica (gray opossum) ENSMMUP00000009522 Macaca mulatta (rhesus monkey) ENSMMUP00000010107 Macaca mulatta (rhesus monkey) ENSMMUP00000034588 Macaca mulatta (rhesus monkey) ENSMMUP00000035786 Macaca mulatta (rhesus monkey) ENSMMUP00000039495 Macaca mulatta (rhesus monkey) ENSMUSP00000078397 Mus musculus (house mouse) ENSMUSP00000093719 Mus musculus (house mouse) ENSMUSP00000099541 Mus musculus (house mouse) ENSMUSP00000100528 Mus musculus (house mouse) 160446 Nematostella vectensis (starlet anemone) XP_001604487.1 Nasonia vitripennis (wasp) ENSOANP00000015173 Ornithorynchus anatinus (platypus) ENSORLP00000006953 Oryzias latipes (japanese killifish) LOC_Os04g42270.1 Oryza sativa (asian rice) 26182 Ostreococcus tauri (green alga) PF13_0132 Plasmodium falciparum (protozoal parasite) PHUM008891-PA Pediculus humanus (human body louse) PP04054 Pristionchus pacificus (nematode) 190449 Physcomitrella patens (moss) 208348 Physcomitrella patens (moss) ENSPPYP00000009116 Pongo pygmaeus (orangutan) 79226 Phytophthora ramorum (sudden oak death pathogen) 95330 Phytophthora ramorum (sudden oak death pathogen) 822509 Populus trichocarpa (black cottonwood) ENSPTRP00000058561 Pan troglodytes (chimpanzee) PVX_116700 Plasmodium vivax (protozoal parasite) ENSRNOP00000036391 Rattus norvegicus (norway rat) ENSRNOP00000043004 Rattus norvegicus (norway rat) ENSRNOP00000049652 Rattus norvegicus (norway rat) 146683 Sorghum bicolor (sorghum) Smp_003410 Schistosoma mansoni (trematode parasite) SPBC106.18 Schizosaccharomyces pombe (fission yeast) XP_792948.2 Strongylocentrotus purpuratus (purple sea urchin) 36440 Trichoplax adhaerens (metazoa) TA17715 Theileria annulata (apicomplexan parasite) XP_967229.1 Tribolium castaneum (red flour beetle) Tc00.1047053509151.140 Trypanosoma cruzi (parasitic trypanosome) 6363 Thalassiosira pseudonana (marine diatom) ENSTRUP00000043745 Takifugu rubripes (pufferfish Takifugu) 3698.m00088 Tetrahymena thermophila (ciliate protozoa) 83472.m00427 Trichomonas vaginalis (parasitic flagellated protozoan) 85746.m00167 Trichomonas vaginalis (parasitic flagellated protozoan) 86319.m00318 Trichomonas vaginalis (parasitic flagellated protozoan) 87835.m00286 Trichomonas vaginalis (parasitic flagellated protozoan) 95287.m00218 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000055350 Xenopus tropicalis (frog) YALI0F25531g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38208 modMine - Data generated by the modENCODE project. • FBgn0026372 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15360 NV13579 LH22940 ISCW024803 FBgn0068075 FBgn0219067 FBgn0199775 FBgn0185165 FBgn0169112 JGI_V11_314559 FBgn0080727 FBgn0150038 FBgn0139540 FBgn0122987 CPIJ000279 BGIBMGA006835 ACYPI007628 GB12508 AGAP006037 AAEL017516 PHUM361800 GLEAN_12708
Synonyms & Secondary IDs ( 21 )
Reported As
Symbol Synonym	153215_at (Kristensen et al., 2005) anon-EST:fe2D1   anon-EST:Liang-1.4   CG7977 (Ashburner, 2004.6.30, Marygold et al., 2007, Keleman et al., 2009.8.5, Cammarato et al., 2011) clone 1.4 (Liang and Biggin, 1998) L23a (Eastman and Ware, 2001, Ross et al., 2007) L23A (Carpenter et al., 2009) PBP-3 (Koyama et al., 1999) RpL23a (Wang et al., 2004, Luschnig, 2003.6.11, Koyama et al., 1999, ) rpl23a (Koyama, 1998.7.24) RpL23A (Beller et al., 2006, Isogai et al., 2007, Tortoriello et al., 2009, Marygold et al., 2007) RPL23a (Pinnola et al., 2007) Rp L23A (Alonso and Santaren, 2006) rpL25 (Dooijes et al., 1998) RpL25   unnamed (Schmid and Tautz, 1997)
Name Synonym	anon-fast-evolving-2D1   PARP-binding protein-3 (Koyama et al., 1999) Ribosomal protein L23A (Ashburner and Marygold, 2004.7.2, Cammarato et al., 2011) Ribosomal protein L23a (Koyama et al., 1999) Ribosomal protein L25
Secondary FlyBase IDs
	FBgn0014878 FBgn0025226 FBgn0025992
References ( 36 )
Generate a list of	All references relating to this gene ( 36 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 1 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 2 )
	Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Müller et al., 2010, EMBO J. 29(19): 3344--3357 Proteomic and functional analysis of the mitotic Drosophila centrosome. [FBrf0212030] Show all research papers ...