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Gene Dmel\Or43a

General Information
Symbol	Dmel\Or43a	Species	D. melanogaster
Name	Odorant receptor 43a	Annotation symbol	CG1854
Feature type	protein_coding_gene	FlyBase ID	FBgn0026389
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	DOR87, AN14
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	43A1-43A1	Sequence location	2R:3,120,344..3,122,418 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Odorant receptor 43a is referred to in FlyBase by the symbol Dmel\Or43a (CG1854, FBgn0026389). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; olfactory receptor activity. It is reported to be involved in the biological process: sensory perception of smell. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Olfactory receptor, Drosophila. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1629154_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Or43a. Gene sequence location is 2R:3120344..3122418.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	References Rollmann et al., 2010, Genetics 186(2): 687--697 Sequence features HFA07485 BKN23455
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 43A1-43A1   Limits computationally determined from genome sequence between P{lacW}vimark16722 and P{lacW}cosk16101
Experimentally Determined Cytological Location
Cytogenetic map Notes References 43B1-43B2     (Vosshall, 1999.2.9)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Or43a for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	<new comment>5' and 3' ends from GB:AF127926.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Or43a-RA FBtr0089051  NM_078923   1532   376
Additional Transcript Data & Comments
Reported size (kB)	1.556 (longest cDNA) (Vosshall et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Or43a-PA   FBpp0088122   43.1   376   9.00     NP_523647   AAF59280
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Olfactory receptor, Drosophila (IPR004117)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF59280   AC005198   AC005425   AF127926 AAD26361   BD268273   BD268322
UniProtKB/Swiss-Prot	P81917
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference adult stage   sensory neuron of third segment of antenna   (Vosshall et al., 1999) adult olfactory receptor neuron Or43a   (Couto et al., 2005)
Additional Descriptive Data
	The transcript is expressed in about 20 cells at the distal edge of the antenna. (Vosshall et al., 1999)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0026389    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0026389 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0026389 expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0026389 expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    2 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    3 embryo 16-18hr    0 embryo 18-20hr    2 embryo 20-22hr    1 embryo 22-24hr    2 larva L1    1 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    1 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    1 white prepupae 12hr    3 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    4 adult male 01day    1 adult male 05day    4 adult male 30day    12 adult female 01day    0 adult female 05day    0 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0026389    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0026389 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0026389 expression level Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0026389 expression level Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut no informative data Larval Hindgut    11.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head    17.4 Adult Eye    8.275 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain no informative data Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    17.4   NA  Eye    8.275   NA  Brain    no informative data   8.425  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    9.1   NA  Crop    12.7   no informative data  Midgut    7.4   11.7  Hindgut    no informative data   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    no informative data   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    7   NA  Testis    5.2   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026389 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1854-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Or43aGD598 Other Phenotypes Allele neurophysiology defective, with Scer\GAL4GH320 Or43aScer\UAS.cSa Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Or43a Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Or43a Class Mutagen Stocks Known lesion Or43aGD598 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Or43aJF02064 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Or43aKK103263 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.cSa in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.cWa in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.T:Avic\GFP-YFP(1) in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.T:Avic\GFP-YFP(2) in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.YFP(1).ZIP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.YFP(2).ZIP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD598} NA P{KK103263} NA P{TRiP.JF02064} NA P{UAS-Or43a.EGFP} NA P{UAS-Or43a.MYC} NA P{UAS-Or43a.S} NA P{UAS-Or43a.W} NA P{UAS-Or43a.YFP(1).ZIP} NA P{UAS-Or43a.YFP(1)} NA P{UAS-Or43a.YFP(2).ZIP} NA P{UAS-Or43a.YFP(2)} NA characterization construct P{Or43a-GAL4.W} NA P{Or43a-Mmus\Cd8a.GFP} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}l(2)SH0301SH0301 No
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function
CV term Evidence References
olfactory receptor activity inferred from direct assay (Hallem and Carlson, 2006, Benton et al., 2006) protein binding inferred from physical interaction with Orco (Benton et al., 2006)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
odorant binding inferred from electronic annotation with InterPro:IPR004117 (FlyBase Curators et al., 2004-) traceable author statement (Keller and Vosshall, 2003) olfactory receptor activity non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1) traceable author statement (Carlson, 2001, Keller and Vosshall, 2003)
Biological Process
CV term Evidence References
sensory perception of smell inferred from electronic annotation with InterPro:IPR004117 (FlyBase Curators et al., 2004-) non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1) traceable author statement (Carlson, 2001)
Cellular Component
CV term Evidence References
integral to membrane non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1, Carlson, 2001) membrane inferred from electronic annotation with InterPro:IPR004117 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Or43a allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0026389 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35644
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12239 Dere\GG10763 Dgri\GH20371 Dmoj\GI20046 Dper\GL10945 Dpse\Or43a Dsec\GM20811 Dsim\GD10268 Dvir\GJ21288 Dwil\GK21525 Dyak\GE24158
Curated drosophilid orthologs	Dpse\Or43a
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV30433 FBgn0241291 FBgn0223517 FBgn0208420 FBgn0182042 FBgn0175692 FBgn0075006 FBgn0148555 FBgn0142782 FBgn0127834 FBgn0103068 FBgn0089277 GB30443 GB30442 GB30441 GB30440 GB30183 GB30182 GB30181 GB19697 GB18980 GB18711 GB18400 GB15842 GB14045 GB13632 GB13305
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	26295 y1 v1; P{TRiP.JF02064}attP2
VDRC	v9346 w1118; P{GD598}v9346
Genomic Clones ( 1 )
	BACR12F04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0026389 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35644
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Or43a Or43B.1 (Warr and Vosshall, 2000.5.19) Source for identity of: Or43B.1 CG1854 (Gabrielian, 1999.11)
Source for database merge of
Additional comments
Other Comments
	Cyclohexanol, cyclohexanone, benzaldehyde and benzyl alcohol are ligands for the Or43a olfactory receptor. (Stortkuhl and Kettler, 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078923 RefSeq (Proteins) • NP_523647 DDBJ / EMBL / GenBank • AAD26361 AAF59280 AC005198 AC005425 AF127926 BD268273 BD268322 Entrez Gene - A searchable database of RefSeq genes. • 35644 UniProtKB/Swiss-Prot • P81917
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Olfactory receptor, Drosophila (IPR004117)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0026389 DRSC - Results from RNAi screens. • FBgn0026389 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026389 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1854-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0026389 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35644 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35644 modMine - Data generated by the modENCODE project. • FBgn0026389 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV30433 FBgn0241291 FBgn0223517 FBgn0208420 FBgn0182042 FBgn0175692 FBgn0075006 FBgn0148555 FBgn0142782 FBgn0127834 FBgn0103068 FBgn0089277 GB30443 GB30442 GB30441 GB30440 GB30183 GB30182 GB30181 GB19697 GB18980 GB18711 GB18400 GB15842 GB14045 GB13632 GB13305
Synonyms & Secondary IDs ( 20 )
Reported As
Symbol Synonym	43a (Vogt et al., 2002) 43B1   43B.1 (Warr and Vosshall, 2000.5.19) AN14 (Warr and Vosshall, 2000.5.19, Gao and Chess, 1999, ) CG1854 (Warr and Vosshall, 2000.5.19, Perkins et al., 2009.3.31, Robertson, 2009, Keleman et al., 2009.8.5) DOR43a (Neuhaus et al., 2005) DOR43B.1 (Clyne et al., 1999) DOR87 (Warr and Vosshall, 2000.5.19, ) Dor87 (Vosshall, 1999.2.9) dor87 (Vosshall et al., 1999) Or (Stortkuhl et al., 2001) Or43A (Bartolome and Maside, 2004) or43a (Roman, 2004) Or43a (Hallem and Carlson, 2006, de Bruyne and Warr, 2006, Komiyama et al., 2004, McBride et al., 2007, van der Goes van Naters and Carlson, 2007, Lattemann et al., 2007, Sachse et al., 2007, Gardiner et al., 2009, Guo and Kim, 2007, Robertson, 2009, Zhou et al., 2009, Galizia et al., 2010, Rollmann et al., 2010) OR43a (Benton et al., 2006) Or43B.1   Or87
Name Synonym	Odorant receptor 43a   Odorant receptor 87   Olfactory receptor 43B.1 (Clyne et al., 1999)
Secondary FlyBase IDs
References ( 54 )
Generate a list of	All references relating to this gene ( 54 )
List References by type	Research paper  ( 29 ) Supplementary material  ( 3 ) Review  ( 6 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 2 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 ) Patent  ( 1 ) Protein sequence record  ( 1 ) Automatic genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 2 )
	Galizia et al., 2010, Chem. Senses 35(7): 551--563 Integrating heterogeneous odor response data into a common response model: A DoOR to the complete olfactome. [FBrf0211579] Rollmann et al., 2010, Genetics 186(2): 687--697 Odorant receptor polymorphisms and natural variation in olfactory behavior in Drosophila melanogaster. [FBrf0212096] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...