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Gene Dmel\Or43a

General Information
Symbol	Dmel\Or43a	Species	D. melanogaster
Name	Odorant receptor 43a	Annotation symbol	CG1854
Feature type	protein_coding_gene	FlyBase ID	FBgn0026389
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	DOR87, AN14
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	43A1-43A1	Sequence location	2R:3,120,345..3,122,418 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Odorant receptor 43a is referred to in FlyBase by the symbol Dmel\Or43a (CG1854, FBgn0026389). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: olfactory receptor activity. There is experimental evidence that it is involved in the biological process: protein heterooligomerization; sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Olfactory receptor, Drosophila. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1629154_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Or43a. Gene sequence location is 2R:3120345..3122418.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 43A1-43A1   Limits computationally determined from genome sequence between P{lacW}vimark16722 and P{lacW}cosk16101
Experimentally Determined Cytological Location
Cytogenetic map Notes References 43B1-43B2     (Vosshall, 1999.2.9)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Or43a for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Or43a-RA FBtr0089051  NM_078923   1531   376
Additional Transcript Data & Comments
Reported size (kB)	1.556 (longest cDNA) (Vosshall et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Or43a-PA   FBpp0088122   43.1   376   9.00     NP_523647   AAF59280
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Olfactory receptor, Drosophila (IPR004117)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF59280   AC005198   AC005425   AF127926 AAD26361   BD268273   BD268322
UniProtKB/Swiss-Prot	P81917
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference adult stage   sensory neuron of third segment of antenna   (Vosshall et al., 1999) adult olfactory receptor neuron Or43a   (Couto et al., 2005)
Additional Descriptive Data
	The transcript is expressed in about 20 cells at the distal edge of the antenna. (Vosshall et al., 1999)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
dendrite membrane inferred from direct assay (Benton et al., 2006) integral to membrane inferred from direct assay (Hallem and Carlson, 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    8.425 Larval Midgut    25 Larval Hindgut    11.7 Larval Malpighian Tubules    11.9 Larval Fat Body    13.2 Larval Salivary Gland    12.6 Larval Trachea    11.6 Larval Carcass    13.3 Adult Head    17.4 Adult Eye    8.275 Adult Brain    10.2 Adult Thoracic-Abdominal Ganglion    9.1 Adult Crop    12.7 Adult Midgut    7.4 Adult Hindgut    13.8 Adult Malpighian Tubules    11.3 Adult Fat Body    19.3 Adult Salivary Gland    25.5 Adult Heart    10.275 Adult VirginFemale Spermatheca    10.4 Adult InseminatedFemale Spermatheca    14.8 Adult Ovary    7 Adult Testis    5.2 Adult Male Accessory Gland    19.5 Adult Carcass    19.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    17.4   NA  Eye    8.275   NA  Brain    no informative data   8.425  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    9.1   NA  Crop    12.7   no informative data  Midgut    7.4   11.7  Hindgut    no informative data   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    no informative data   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    7   NA  Testis    5.2   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026389 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1854-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Or43aGD598 Other Phenotypes Allele neurophysiology defective, with Scer\GAL4GH320 Or43aScer\UAS.cSa Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of Or43a Class Mutagen Stocks Known lesion Or43aF333I natural population 0 Yes Or43aI170M natural population 0 Yes Or43aL287M natural population 0 Yes Or43aV254A natural population 0 Yes
Alleles Carried on Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Or43a Class Mutagen Stocks Known lesion Or43aGD598 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Or43aJF02064 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Or43aKK103263 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.cSa in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.cWa in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.T:Avic\GFP-YFP(1) in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.T:Avic\GFP-YFP(2) in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion 0 Yes Or43aScer\UAS.YFP(1).ZIP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Or43aScer\UAS.YFP(2).ZIP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD598} NA P{KK103263} NA P{TRiP.JF02064} NA P{UAS-Or43a.EGFP} NA P{UAS-Or43a.MYC} NA P{UAS-Or43a.S} NA P{UAS-Or43a.W} NA P{UAS-Or43a.YFP(1).ZIP} NA P{UAS-Or43a.YFP(1)} NA P{UAS-Or43a.YFP(2).ZIP} NA P{UAS-Or43a.YFP(2)} NA GAL4 construct P{Or43a-GAL4.C} No characterization construct P{Or43a-GAL4.W} NA P{Or43a-Mmus\Cd8a.GFP} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}l(2)SH0301SH0301 No
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function
CV term Evidence References
olfactory receptor activity inferred from direct assay (Hallem and Carlson, 2006, Benton et al., 2006)
Biological Process
CV term Evidence References
detection of chemical stimulus involved in sensory perception of smell inferred from direct assay (Hallem and Carlson, 2006) protein heterooligomerization inferred from physical interaction with Orco (Benton et al., 2006) sensory perception of smell inferred from expression pattern (Vosshall et al., 1999)
Cellular Component
CV term Evidence References
dendrite membrane inferred from direct assay (Benton et al., 2006) integral to membrane inferred from direct assay (Hallem and Carlson, 2006)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
odorant binding inferred from electronic annotation with InterPro:IPR004117 (FlyBase Curators et al., 2004-) traceable author statement (Keller and Vosshall, 2003) olfactory receptor activity inferred by curator from GO:0004888|GO:0007608 (Vosshall et al., 1999) non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1) traceable author statement (Carlson, 2001, Keller and Vosshall, 2003) transmembrane signaling receptor activity inferred from sequence model (Vosshall et al., 1999)
Biological Process
CV term Evidence References
sensory perception of smell non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1) traceable author statement (Carlson, 2001)
Cellular Component
CV term Evidence References
integral to membrane inferred from sequence model (Vosshall et al., 1999) non-traceable author statement (Vosshall, 1999.2.9, Swiss-Prot Project Members, 2000.10.1, Carlson, 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Or43a allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0026389 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35644
Orthologs
OrthoDB Orthologs (19) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG64F6W8 Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6H450K Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG64F6W8)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Or43a     Drosophila simulans   Dsim\GD10268 Y   Drosophila sechellia   Dsec\GM20811 Y   Drosophila erecta   Dere\GG10763 Y   Drosophila yakuba   Dyak\GE24158 Y   Drosophila ananassae   Dana\GF12239 Y   Drosophila pseudoobscura pseudoobscura   Dpse\Or43a Y   Drosophila persimilis   Dper\GL10945 Y   Drosophila willistoni   Dwil\GK21525 Y   Drosophila virilis   Dvir\GJ21288 Y   Drosophila mojavensis   Dmoj\GI20046 Y   Drosophila grimshawi   Dgri\GH20371 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6H450K)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB52364   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG036929   Atta cephalotes Leafcutter ant  Acep\ACEP18666   Atta cephalotes Leafcutter ant  Acep\ACEP18665   Camponotus floridanus Florida carpenter ant  Cflo\CFLO25109   Camponotus floridanus Florida carpenter ant  Cflo\CFLO25110   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11551
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD10268 Drosophila sechellia Dsec\GM20811 Drosophila erecta Dere\GG10763 Drosophila yakuba Dyak\GE24158 Drosophila ananassae Dana\GF12239 Drosophila pseudoobscura pseudoobscura Dpse\Or43a Drosophila persimilis Dper\GL10945 Drosophila willistoni Dwil\GK21525 Drosophila virilis Dvir\GJ21288 Drosophila mojavensis Dmoj\GI20046 Drosophila grimshawi Dgri\GH20371
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	26295 y1 v1; P{TRiP.JF02064}attP2
VDRC	v9346 w1118; P{GD598}v9346
Genomic Clones ( 1 )
	BACR12F04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0026389 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35644
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Or43a Or43B.1 (Warr and Vosshall, 2000.5.19) Source for identity of: Or43B.1 CG1854 (Gabrielian, 1999.11)
Source for database merge of
Additional comments
Other Comments
	Cyclohexanol, cyclohexanone, benzaldehyde and benzyl alcohol are ligands for the Or43a olfactory receptor. (Stortkuhl and Kettler, 2001)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078923 RefSeq (Proteins) • NP_523647 DDBJ / EMBL / GenBank • AAD26361 AAF59280 AC005198 AC005425 AF127926 BD268273 BD268322 Entrez Gene - A searchable database of RefSeq genes. • 35644 UniProtKB/Swiss-Prot • P81917
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Olfactory receptor, Drosophila (IPR004117)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0026389 DRSC - Results from RNAi screens. • FBgn0026389 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026389 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1854-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0026389 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35644 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35644 modMine - Data generated by the modENCODE project. • FBgn0026389
Synonyms & Secondary IDs ( 20 )
Reported As
Symbol Synonym	43a (Vogt et al., 2002) 43B1   43B.1 (Warr and Vosshall, 2000.5.19) AN14 (Warr and Vosshall, 2000.5.19, Gao and Chess, 1999, ) CG1854 (Warr and Vosshall, 2000.5.19, Perkins et al., 2009.3.31, Robertson, 2009, Keleman et al., 2009.8.5) DOR43a (Neuhaus et al., 2005) DOR43B.1 (Clyne et al., 1999) DOR87 (Warr and Vosshall, 2000.5.19, ) Dor87 (Vosshall, 1999.2.9) dor87 (Vosshall et al., 1999) Or (Stortkuhl et al., 2001) Or43A (Bartolome and Maside, 2004) or43a (Roman, 2004) Or43a (Hallem and Carlson, 2006, de Bruyne and Warr, 2006, Komiyama et al., 2004, Jafari et al., 2012, McBride et al., 2007, van der Goes van Naters and Carlson, 2007, Lattemann et al., 2007, Sachse et al., 2007, Tunstall et al., 2007, Gardiner et al., 2009, Guo and Kim, 2007, Immonen and Ritchie, 2012, Robertson, 2009, Zhou et al., 2009, Galizia et al., 2010, Stortkuhl et al., 2005, Rollmann et al., 2010, Endo et al., 2011, Richgels and Rollmann, 2012) OR43a (Benton et al., 2006) Or43B.1   Or87
Name Synonym	Odorant receptor 43a   Odorant receptor 87   Olfactory receptor 43B.1 (Clyne et al., 1999)
Secondary FlyBase IDs
References ( 62 )
Generate a list of	All references relating to this gene ( 62 )
List References by type	Research paper  ( 36 ) Supplementary material  ( 4 ) Review  ( 6 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 2 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 3 ) Patent  ( 1 ) Protein sequence record  ( 1 ) Letter  ( 1 )
Recent research papers ( 5 )
	Immonen and Ritchie, 2012, Proc. Biol. Sci. 279(1732): 1359--1365 The genomic response to courtship song stimulation in female Drosophila melanogaster. [FBrf0217554] Jafari et al., 2012, PLoS Biol. 10(3): e1001280 Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression. [FBrf0217822] Richgels and Rollmann, 2012, Chem. Senses 37(3): 229--240 Genetic Variation in Odorant Receptors Contributes to Variation in Olfactory Behavior in a Natural Population of Drosophila melanogaster. [FBrf0217489] Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Endo et al., 2011, Nat. Neurosci. 15(2): 224--233 Chromatin modification of Notch targets in olfactory receptor neuron diversification. [FBrf0217319] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...