l(2)ND3, dynamin-2, l(2)ND2, noodle, Drp-1
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Drp1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Drp1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Drp1 is required for the normal distribution of mitochondria in spermatocytes and the normal unfurling of the mitochondrial derivatives in early spermatids during sperm formation.
Drp1 is required for normal mitochondrial distribution and morphology in all cells tested.
Mutants show a defect in the formation and recruitment of the synaptic vesicle reserve pool.
dsRNA directed against this gene causes defects in cytokinesis when tested in an RNAi screen in S2 cells.
Required at the neuromuscular junction.
Mutants show a distinct temperature sensitive paralysis phenotype.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
The gene is named "fratboy" after the mutant phenotype; adult escaper flies are uncoordinated and show numerous neurological defects.