E-APC, dAPC2, D-APC2, APC
Gene model reviewed during 5.47
Supported by strand-specific RNA-Seq data.
Antisense (in part): overlaps CG5510 on opposite strand.
Gene model reviewed during 6.09
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Apc2 using the Feature Mapper tool.
Apc2 protein is expressed in all embryonic cells, and at low levels in most larval tissues. In syncyctial blastoderms, Apc2 protein is localized to cortical actin caps that lie above each nucleus; costaining with antibodies to tubulin indicates at Apc2 protein does not bind direction to microtubules. As embryos cellularize, Apc2 protein delocalizes from the actin caps to become associated with membranes.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Apc2 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Apc2 CG6193
dsRNA made from templates generated with primers directed against this gene.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identification: Isolated in a yeast two hybrid screen that used arm protein as the bait.