FlyBase Gene Report: Dmel\tacc

General Information

Symbol

Dmel\tacc

Species

D. melanogaster

Name

transforming acidic coiled-coil protein

Annotation Symbol

CG9765

Feature Type

protein_coding_gene

FlyBase ID

FBgn0026620

Gene Model Status

Stock Availability

17 publicly available

Gene Snapshot

transforming acidic coiled-coil protein (tacc) encodes a centrosomal protein that helps to stabilize microtubules. It seems to influence microtubules indirectly, primarily through its interaction with the product of msps. It is also phosphorylated by the product of aurA, and this activates its ability to stabilize microtubules. [Date last reviewed: 2019-03-14]

Other Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

D-TACC, dTACC

Key Links

Genomic Location

Cytogenetic map

Sequence location

3R:4,733,654..4,749,056 [-]

Recombination map

3-47.1

RefSeq locus

NT_033777 REGION:4733654..4749056

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (18 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with FLYBASE:msps; FB:FBgn0027948

(Lee et al., 2001)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables microtubule binding

traceable author statement

(Gergely, 2002)

Biological Process (11 terms)

Terms Based on Experimental Evidence (6 terms)

CV Term

Evidence

References

involved_in microtubule cytoskeleton organization

inferred from mutant phenotype

(Gergely et al., 2000)

involved_in mitotic cell cycle

inferred from mutant phenotype

(Gergely et al., 2000)

involved_in nuclear migration

inferred from mutant phenotype

(Gergely et al., 2000)

involved_in pole cell formation

inferred from mutant phenotype

(Lerit and Gavis, 2011)

involved_in pronuclear migration

inferred from mutant phenotype

(Gergely et al., 2000)

involved_in protein localization

inferred from mutant phenotype

(Lee et al., 2001)

Terms Based on Predictions or Assertions (6 terms)

CV Term

Evidence

References

involved_in cell population proliferation

inferred from biological aspect of ancestor with PANTHER:PTN001016925

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in female meiotic nuclear division

traceable author statement

(Gergely, 2002)

involved_in microtubule cytoskeleton organization

inferred from biological aspect of ancestor with PANTHER:PTN001016925

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in mitotic spindle organization

inferred from electronic annotation with InterPro:IPR039915

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

traceable author statement

(Gergely, 2002)

involved_in negative regulation of microtubule depolymerization

traceable author statement

(Gergely, 2002)

involved_in pronuclear fusion

traceable author statement

(Gergely, 2002, Lee et al., 2001)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

located_in astral microtubule

inferred from direct assay

(Gergely et al., 2000)

colocalizes_with centrosome

inferred from direct assay

(Sabino et al., 2011)

located_in centrosome

inferred from direct assay

(Barros et al., 2005, Giet et al., 2002, Gergely et al., 2000)

located_in spindle microtubule

inferred from direct assay

(Giet et al., 2002, Gergely et al., 2000)

located_in spindle pole

inferred from direct assay

(Meireles et al., 2009)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in astral microtubule

traceable author statement

(Gergely, 2002)

located_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN001016925

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

Protein Family (UniProt)

-

Protein Signatures (InterPro)

Summaries

Summary (Interactive Fly)

centrosomal protein that stabilizes microtubules during mitosis by recruiting the microtubule plus end binding protein Minispindles

Interactive Fly

Gene Model and Products

Number of Transcripts

13

Number of Unique Polypeptides

9

Please see the JBrowse view of Dmel\tacc for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.45

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.46

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Sequence Ontology: Class of Gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0089955

4593

1226

FBtr0089953

4906

1308

FBtr0089952

4861

1293

FBtr0089949

1799

245

FBtr0089951

1792

245

FBtr0089950

1834

245

FBtr0302613

2599

245

FBtr0302614

4596

1227

FBtr0302615

4554

1213

FBtr0302616

5706

1322

FBtr0306654

4475

1225

FBtr0332445

4637

1320

FBtr0332446

4789

1225

Additional Transcript Data and Comments

Reported size (kB)

4.626 (longest cDNA)

(Gergely et al., 2000)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

FBpp0088894

136.6

1226

4.67

FBpp0088892

145.6

1308

4.64

FBpp0088891

144.0

1293

4.66

FBpp0088888

28.6

245

5.34

FBpp0088890

28.6

245

5.34

FBpp0088889

28.6

245

5.34

FBpp0291769

28.6

245

5.34

FBpp0291770

136.7

1227

4.68

FBpp0291771

135.1

1213

4.70

FBpp0291772

147.2

1322

4.62

FBpp0297609

136.5

1225

4.81

FBpp0304718

147.1

1320

4.61

FBpp0304719

136.5

1225

4.81

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

245 aa isoforms: tacc-PE, tacc-PF, tacc-PG, tacc-PH

1225 aa isoforms: tacc-PL, tacc-PN

Additional Polypeptide Data and Comments

Reported size (kDa)

1190 (aa); 220 (kD observed)

(Gergely et al., 2000)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tacc using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

No Assay Recorded

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

• spindle

(Giet et al., 2002)

• centrosome

(Giet et al., 2002)

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

• astral microtubule & spindle microtubule

(Gergely et al., 2000)

• centrosome

(Gergely et al., 2000)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Staining of embryos with antibodies against tacc reveals strong staining of the centrosomes and weak staining of the spindle microtubules.

(Giet et al., 2002)

Protein was highly concentrated at centrosomes throughout the cell cycle and low levels of staining were observed in astral microtubules and spindle microtubules.

(Gergely et al., 2000)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in astral microtubule

inferred from direct assay

(Gergely et al., 2000)

colocalizes_with centrosome

inferred from direct assay

(Sabino et al., 2011)

located_in centrosome

inferred from direct assay

(Barros et al., 2005, Giet et al., 2002, Gergely et al., 2000)

located_in spindle microtubule

inferred from direct assay

(Giet et al., 2002, Gergely et al., 2000)

located_in spindle pole

inferred from direct assay

(Meireles et al., 2009)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\tacc in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\tacc

View exonic expression by tissue for Dmel\tacc

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0026620

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG9765-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9765

Flygut - An atlas of the Drosophila adult midgut

FBgn0026620

Images

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 28 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 13 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of tacc

Transgenic constructs containing regulatory region of tacc

Deletions and Duplications ( 3 )

Disrupted in

(Gergely et al., 2000)

(Ryder, 2004.4.26)

(Gergely et al., 2000)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal - all die before end of embryonic stage

tacc^stella592

lethal - all die before end of embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

tacc^{TD.UASp.Tag:GST}

Sterility

Allele

tacc¹

Other Phenotypes

Allele

mitotic cell cycle defective

tacc^stella592

some die during embryonic stage

tacc^stella592

some die during embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

tacc^{TD.UASp.Tag:GST}

Phenotype manifest in

Allele

astral microtubule

tacc^{S863L.Ubi-p63E.GFP}

tacc¹

centrosome | ectopic

tacc^stella592

embryonic/larval salivary gland, with Scer\GAL4^fkh.PH

tacc^EP341

tacc¹

mitotic cell cycle

tacc¹

nucleus | embryonic stage

tacc¹

oocyte & spindle (with Df(3R)110)

tacc¹

pericentriolar material

tacc¹

primordial germ cell (with Df(3R)110)

tacc¹

tacc¹

spindle & oocyte

tacc^stella592

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

7 of 15

Yes

Yes

7 of 15

Yes

Yes

1

6 of 15

No

Yes

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (4)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

6 of 15

Yes

Yes

5 of 15

No

Yes

5 of 15

No

Yes

1 of 15

No

Yes

Rattus norvegicus (Norway rat) (3)

5 of 13

Yes

Yes

4 of 13

No

Yes

2 of 13

No

Yes

Xenopus tropicalis (Western clawed frog) (3)

4 of 12

Yes

Yes

3 of 12

No

Yes

1 of 12

No

Yes

Danio rerio (Zebrafish) (3)

6 of 15

Yes

Yes

5 of 15

No

Yes

3 of 15

No

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

1 of 15

Yes

Yes

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG0919017Q )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00008596

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Drosophila persimilis

Drosophila willistoni

Drosophila virilis

Drosophila mojavensis

Drosophila grimshawi

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091504EE )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Glossina morsitans

Tsetse fly

Gmor\GMOY007379

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_04149

Mayetiola destructor

Hessian fly

Mdes\Mdes001918

Anopheles darlingi

American malaria mosquito

Adar\ADAC000150

Anopheles gambiae

Malaria mosquito

Agam\AGAP010297

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ007378

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0HE0 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA005040

Bombyx mori

Silkmoth

Bmor\BGIBMGA004787

Danaus plexippus

Monarch butterfly

Dple\DPOGS204157-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL004121

Apis florea

Little honeybee

Aflo\2669752452

Apis mellifera

Western honey bee

Bombus impatiens

Common eastern bumble bee

Bombus terrestris

Buff-tailed bumblebee

Linepithema humile

Argentine ant

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0004b8

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG020754

Dendroctonus ponderosae

Mountain pine beetle

Dendroctonus ponderosae

Mountain pine beetle

Tribolium castaneum

Red flour beetle

Tribolium castaneum

Red flour beetle

Pediculus humanus

Human body louse

Phum\PHUM174950

Pediculus humanus

Human body louse

Phum\PHUM467120

Rhodnius prolixus

Kissing bug

Rpro\RPRC009952

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI006083

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_02770

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0HFV )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR000774

Ixodes scapularis

Black-legged tick

Isca\ISCW017142

Ixodes scapularis

Black-legged tick

Isca\ISCW017143

Stegodyphus mimosarum

African social velvet spider

Smim\KFM72172.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM72183.1

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_304681

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )

No non-Arthropod Metazoa orthologies identified

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (0)

No records found.

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TACC1; transforming acidic coiled-coil containing protein 1

7 of 15

TACC3; transforming acidic coiled-coil containing protein 3

7 of 15

TACC2; transforming acidic coiled-coil containing protein 2

6 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

experimental knowledge based

(Guruharsha et al., 2011)

(Galletta et al., 2016)

(Galletta et al., 2016)

pull down, peptide massfingerprinting

(Gillingham et al., 2014)

(Galletta et al., 2016)

(Galletta et al., 2016)

(Galletta et al., 2016)

two hybrid, enzymatic study, autoradiography, anti tag coimmunoprecipitation, western blot, anti bait coimmunoprecipitation

(Galletta et al., 2016, Giet et al., 2002)

(Galletta et al., 2016)

anti bait coimmunoprecipitation, western blot

(Bucciarelli et al., 2009)

anti bait coimmunoprecipitation, western blot, peptide massfingerprinting

(Sato et al., 2011)

anti tag coimmunoprecipitation, western blot

(Tan et al., 2008)

anti bait coimmunoprecipitation, western blot, coimmunoprecipitation, pull down, Identification by mass spectrometry, anti tag coimmunoprecipitation, anti tag western blot, experimental knowledge based

(Tang et al., 2020, Guruharsha et al., 2011, Barros et al., 2005, Lee et al., 2001)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Jang et al., 2005)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Tan et al., 2008)

enhanceable

(Jang et al., 2005)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

65806

DroID - A comprehensive database of gene and protein interactions.

FBgn0026620

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

40589

MIST (protein-protein) - An integrated Molecular Interaction Database

tacc

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

RNA transport

Genomic Location and Detailed Mapping Data

Chromosome (arm)

3R

Recombination map

3-47.1

Cytogenetic map

Sequence location

3R:4,733,654..4,749,056 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

82D2-82D2

Limits computationally determined from genome sequence between P{PZ}l(3)02733⁰²⁷³³ and P{EP}EP974

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

82D-82D

(Kramer, 1999.4.29)

82C-82C

(Raff, 1999.4.29)

Experimentally Determined Recombination Data

Location

3-47.1

(FlyBase, 2016)

3-44.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (17)

7066

P{Ubi-tacc.GFP}1, y¹ w^*

63294

w¹¹¹⁸; PBac{IT.GAL4}tacc^0402-G4

59549

y¹ w^*; Mi{MIC}tacc^MI14623

60198

y¹ w^*; Mi{PT-GFSTF.0}tacc^{MI03410-GFSTF.0}

65982

y¹ sc^* v¹ sev²¹; P{TRiP.HMC06268}attP2

104411

w^*; P{GawB}tacc^NP3204

123563

w¹¹¹⁸; P{RS3}tacc^CB-5315-3

125939

w¹¹¹⁸; P{RS5}tacc^5-SZ-3192

126081

w¹¹¹⁸; P{RS5}tacc^5-SZ-3472

v101439

P{KK109162}VIE-260B

v110633

P{KK108100}VIE-260B

v342490

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01794}attP40/CyO-GFP

More stocks available...

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (113)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0026620

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0026620

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40589

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Chou et al., 2020)

polyclonal

(Kao and Megraw, 2009, Giet et al., 2002, Gergely et al., 2000)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Additional comments

Other Comments

sub mutants do not interact with alleles of γTub37C, αTub67C, msps, tacc or wisp.

(Giunta et al., 2002)

tacc is essential for mitotic spindle function in the early embryo.

(Gergely et al., 2000)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 103 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40589

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0026620

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9765

Flygut - An atlas of the Drosophila adult midgut

FBgn0026620

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40589

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG9765

modMine - A data warehouse for the modENCODE project

FBgn0026620

Linkouts

BioGRID - A database of protein and genetic interactions.

65806

DroID - A comprehensive database of gene and protein interactions.

FBgn0026620

DRSC - Results frm RNAi screens

FBgn0026620

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0026620

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG9765-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0026620

FlyMine - An integrated database for Drosophila genomics

FBgn0026620

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

40589

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

RNA transport

MIST (protein-protein) - An integrated Molecular Interaction Database

tacc

Synonyms and Secondary IDs (16)

Reported As

Symbol Synonym

CG9765

(Müller et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009, Hughes et al., 2008, Brown and Feder, 2005)

D-TACC

(Loh et al., 2012, Reschen et al., 2012, Hughes et al., 2011, Sato et al., 2011, Wang et al., 2011, Wang et al., 2011, Conduit et al., 2010, Bucciarelli et al., 2009, Kao and Megraw, 2009, Meireles et al., 2009, Colombié et al., 2008, Ducat et al., 2008, Fisher et al., 2008, Hughes et al., 2008, Megraw et al., 2008, Mottier et al., 2008, Basto et al., 2007, Garcia et al., 2007, Lucas and Raff, 2007, Pandey et al., 2007, Zhang and Megraw, 2007, Basto et al., 2006, Hutterer et al., 2006, Barros et al., 2005, Brittle and Ohkura, 2005, Brittle and Ohkura, 2005, Cullen and Ohkura, 2005, Cullen et al., 2005, Pearson et al., 2005, Fischer et al., 2004, Martinez-Campos et al., 2004, Blagden and Glover, 2003, Kramer and Hawley, 2003, Bolivar et al., 2001, de Carcer et al., 2001, Kramer et al., 2001, Ohkura, 2001, Ohkura et al., 2001, Scholey et al., 2001, Wells, 2001, Gergely et al., 2000, Gonzalez and Bornens, 2000, Gergely et al., 1999)

D-tacc

(Kramer et al., 2004)

DTACC

(Lattao et al., 2017, Zhang et al., 2009, Martins et al., 2007, Stevenson et al., 2001)

TACC

(Rui et al., 2020, Costa and Ohkura, 2019, Galletta et al., 2016, Richens et al., 2015, Cesario and McKim, 2011, Ma and Jarman, 2011, Anderson et al., 2009, Kao and Megraw, 2009, McCleland et al., 2009, Moshkin et al., 2009, Wen et al., 2008, Jang et al., 2007, Pandey et al., 2007, Danchin and Pontarotti, 2004, Gergely et al., 2000)

TACCdm

(Still et al., 2004)

acc

(Coulier et al., 2000)

d-tacc

(Hughes et al., 2018, Giansanti et al., 2008, Barros et al., 2005, Cullen et al., 2005, Cullen et al., 2005, Kwon and Scholey, 2004, Moon and Hazelrigg, 2004, Gergely, 2002, Giet et al., 2002, Giunta et al., 2002, McKim et al., 2002, Cullen and Ohkura, 2001, Lee et al., 2001, Lee et al., 2001, Theurkauf, 2001)

dTACC

(Chou et al., 2020, Tan et al., 2008, Tan et al., 2007, Still et al., 2004, Hafer and Schedl, 2003)

dtacc

(Lerit and Gavis, 2011, Raff, 2002)

tacc

(Tang et al., 2020, Zheng et al., 2020, Blake-Hedges and Megraw, 2019, Myat et al., 2019, Clandinin and Owens, 2016-, Gene Disruption Project members, 2015-, Ashwal-Fluss et al., 2014, Moshkin et al., 2013, Abruzzi et al., 2011, Sabino et al., 2011, Müller et al., 2010, Maybeck and Röper, 2009, McCleland and O'Farrell, 2008, Lucas and Raff, 2007, Mukai et al., 2006, Brown and Feder, 2005, Jang et al., 2005)

Name Synonyms

D. melanogaster transforming acidic coiled coil

(Meireles et al., 2009)

Drosophila Transforming Acidic Coiled-Coil protein

(Tan et al., 2007)

Drosophila transforming acidic coiled-coil

(Tan et al., 2008)

transforming acidic coiled-coil

(McCleland et al., 2009)

transforming acidic coiled-coil protein

(Sabino et al., 2011, Mukai et al., 2006, Kramer, 1999.4.29)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (138)