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Gene Dmel\tacc

General Information
Symbol	Dmel\tacc	Species	D. melanogaster
Name	transforming acidic coiled-coil protein	Annotation symbol	CG9765
Feature type	protein_coding_gene	FlyBase ID	FBgn0026620
Gene Model Status	Current	Stock availability	15 publicly available
Also Known As	D-TACC, dtacc
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	82D2-82D2	Sequence location	3R:560,134..574,777 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene transforming acidic coiled-coil protein is referred to in FlyBase by the symbol Dmel\tacc (CG9765, FBgn0026620). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: protein localization; pronuclear migration; mitosis; pole cell formation; microtubule cytoskeleton organization; nuclear migration. 31 alleles are reported. The phenotypes of these alleles are annotated with: pronucleus; mitotic cell cycle; pole cell; centrosome; spindle; microtubule; astral microtubule; pericentriolar material; aster. It has 11 annotated transcripts and 11 annotated polypeptides. Protein features are: Transforming acidic coiled-coil. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval salivary gland, larval trachea, adult ovary, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625034_s_at completely aligns to an exonic region common to each of the 10 FlyBase-annotated transcript isoforms of tacc. Gene sequence location is 3R:560134..574777.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Wang et al., 2011, PLoS Genet. 7(8): e1002227
FB2012_01	Sequence features HFA12019 BKN28100 HFA12388 BKN29162
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 82D2-82D2   Limits computationally determined from genome sequence between P{PZ}l(3)0273302733 and P{EP}EP974
Experimentally Determined Cytological Location
Cytogenetic map Notes References 82D-82D     (Kramer, 1999.4.29) 82C-82C     (Raff, 1999.4.29)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\tacc for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) tacc-RA FBtr0089955  NM_058086   4592   1226 tacc-RC FBtr0089953  NM_058085   4906   1308 tacc-RD FBtr0089952  NM_176401   4861   1293 tacc-RE FBtr0089949  NM_176402   1827   245 tacc-RF FBtr0089951  NM_176403   1792   245 tacc-RG FBtr0089950  NM_176404   1834   245 tacc-RH FBtr0302613  NM_001202238   1869   245 tacc-RI FBtr0302614  NM_169016   4595   1227 tacc-RJ FBtr0302615  NM_001202239   4553   1213 tacc-RK FBtr0302616  NM_001202240   4948   1322 tacc-RL FBtr0306654     4475   1225
Additional Transcript Data & Comments
Reported size (kB)	4.626 (longest cDNA) (Gergely et al., 2000)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein tacc-PA   FBpp0088894   136.6   1226   4.67     NP_477434   AAN13287 tacc-PC   FBpp0088892   145.6   1308   4.64     NP_477433   AAN13288 tacc-PD   FBpp0088891   144.0   1293   4.66     NP_788578   AAO41502 tacc-PE   FBpp0088888   28.6   245   5.34     NP_788579   AAO41503 tacc-PF   FBpp0088890   28.6   245   5.34     NP_788580   AAO41504 tacc-PG   FBpp0088889   28.6   245   5.34     NP_788581   AAO41505 tacc-PH   FBpp0291769   28.6   245   5.34     NP_001189167   ADV37259 tacc-PI   FBpp0291770   136.7   1227   4.68     NP_730867   AAF52099 tacc-PJ   FBpp0291771   135.1   1213   4.70     NP_001189168   ADV37260 tacc-PK   FBpp0291772   147.2   1322   4.62     NP_001189169   ADV37261 tacc-PL   FBpp0297609   136.5   1225   4.81
Additional Polypeptide Data & Comments
Reported size (kDa)	1190 (aa); 220 (kD observed) (Gergely et al., 2000)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Transforming acidic coiled-coil (IPR007707)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA440629   AA801991   AE014297 AAF52099   AE014297 AAN13287   AE014297 AAN13288   AE014297 AAO41502   AE014297 AAO41503   AE014297 AAO41504   AE014297 AAO41505   AC008189   AE014297 ADV37259   AE014297 ADV37260   AE014297 ADV37261   AF146700 AAD30171   AF146756 AAF66735   AI108468   AI238367   AI388378   AI517361   AI534544   AI542041   AQ025066   AW942358   AY058499 AAL13728   AY231679   BF488332   BF491339   BF496322   BG633615   BG639840   BI164573   BI167042   BI215686   BI242859   BI356541   BI371538   BI483411   BI639665   BT099701   BT122068   BT126053   CL528090   CO154337   CO177051   CO179063   CO181149   CO195366   CO262291   CO262459   CO264040   CO266728   CO271088   CO271108   CO272193   CO272614   CO272795   CO274047   CO278899   CO279660   CO281211   CO283970   CO285526   CO286063   CO287159   CO288225   CO294140   CO298168   CO298234   CO298978   CO300355   CO301320   CO302225   CO303758   CO307688   CO310683   CO311657   CO313721   CO314102   CO315119   CO316757   CO320350   CO322574   CO323530   CO323585   CO324186   CO326331   CO326962   CO339458   CZ473513   CZ473764   CZ473880   CZ473881   CZ477479   CZ484410   CZ484411   CZ485696   CZ488522   CZ488523   DQ017404 AAY82186   DQ017405 AAY82187   EC058232   EC060314   EC062635   EC070127   EC072043   EC078672   EC084709   EC088431   EC088964   EC195721   EC196603   EC199093   EC199491   EC199945   EC200010   EC200584   EC202677   EC212048   EC218747   EC220235   EC223633   EC230363   EC230987   EC232382   EC232882   EC233245   EC237333   EC241733   EC243774   EC246916   EC247897   EC248032   EC252998   EC254137   EC256538   EC265568   EV594527   EV594627   GH941417   GH945479   GH945829   GH946232   GH948223   GH958337   GH958450   GH959187   GH960962   GH961460   GH962277   GH963120   GH964001   GH965001   GH965916   GH966003   GH966054   GH969856   GH976191
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q3YNE8 Q86BB4 Q86BB5 Q8IPN1 Q95TU9 Q9NJH5 Q9VN51 Q9XZL7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference embryonic stage     • spindle (Giet et al., 2002)   • centrosome (Giet et al., 2002) immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism   • astral microtubule & spindle microtubule (Gergely et al., 2000) organism   • centrosome (Gergely et al., 2000)
Additional Descriptive Data
	Staining of embryos with antibodies against tacc reveals strong staining of the centrosomes and weak staining of the spindle microtubules. (Giet et al., 2002) Protein was highly concentrated at centrosomes throughout the cell cycle and low levels of staining were observed in astral microtubules and spindle microtubules. (Gergely et al., 2000)
Marker for
Subcellular Localization
CV Term	centrosome ; GO:0005813 (Gergely et al., 2000)
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0026620    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0026620 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0026620 expression level Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1263 embryo 04-06hr    2893 embryo 06-08hr    3042 embryo 08-10hr    3028 embryo 10-12hr    3352 embryo 12-14hr    3854 embryo 14-16hr    1772 embryo 16-18hr    1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr    1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6    2856 larva L3 puffstage 7-9    3968 white prepupae new    3586 white prepupae 12hr    3307 white prepupae 24hr    3179 pupae 2d postWPP    3006 pupae 3d postWPP    3730 pupae 4d postWPP    1493 adult male 01day    2714 adult male 05day    2461 adult male 30day    1933 adult female 01day    1696 adult female 05day    2827 adult female 30day    2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr  (1263) embryo 04-06hr  (2893) embryo 06-08hr  (3042) embryo 08-10hr  (3028) embryo 10-12hr  (3352) embryo 12-14hr  (3854) embryo 14-16hr  (1772) embryo 16-18hr  (1900) embryo 18-20hr  (1225) embryo 20-22hr  (1055) embryo 22-24hr  (1494) larva L1  (923) larva L2  (1048) larva L3 12hr old  (973) larva L3 puffstage 1-2  (1360) larva L3 puffstage 3-6  (2856) larva L3 puffstage 7-9  (3968) white prepupae new  (3586) white prepupae 12hr  (3307) white prepupae 24hr  (3179) pupae 2d postWPP  (3006) pupae 3d postWPP  (3730) pupae 4d postWPP  (1493) adult male 01day  (2714) adult male 05day  (2461) adult male 30day  (1933) adult female 01day  (1696) adult female 05day  (2827) adult female 30day  (2416) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr    1263 embryo 04-06hr  (2893) embryo 06-08hr  (3042) embryo 08-10hr  (3028) embryo 10-12hr  (3352) embryo 12-14hr  (3854) embryo 14-16hr  (1772) embryo 16-18hr  (1900) embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr  1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6  (2856) larva L3 puffstage 7-9  (3968) white prepupae new  (3586) white prepupae 12hr  (3307) white prepupae 24hr  (3179) pupae 2d postWPP  (3006) pupae 3d postWPP  (3730) pupae 4d postWPP  1493 adult male 01day  (2714) adult male 05day  (2461) adult male 30day  (1933) adult female 01day  (1696) adult female 05day  (2827) adult female 30day  (2416) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1263 embryo 04-06hr    2893 embryo 06-08hr    3042 embryo 08-10hr    3028 embryo 10-12hr    3352 embryo 12-14hr    3854 embryo 14-16hr    1772 embryo 16-18hr    1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr    1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6    2856 larva L3 puffstage 7-9    3968 white prepupae new    3586 white prepupae 12hr    3307 white prepupae 24hr    3179 pupae 2d postWPP    3006 pupae 3d postWPP    3730 pupae 4d postWPP    1493 adult male 01day    2714 adult male 05day    2461 adult male 30day    1933 adult female 01day    1696 adult female 05day    2827 adult female 30day    2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1263 embryo 04-06hr    2893 embryo 06-08hr    3042 embryo 08-10hr    3028 embryo 10-12hr    3352 embryo 12-14hr    3854 embryo 14-16hr    1772 embryo 16-18hr    1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr    1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6    2856 larva L3 puffstage 7-9    3968 white prepupae new    3586 white prepupae 12hr    3307 white prepupae 24hr    3179 pupae 2d postWPP    3006 pupae 3d postWPP    3730 pupae 4d postWPP    1493 adult male 01day    2714 adult male 05day    2461 adult male 30day    1933 adult female 01day    1696 adult female 05day    2827 adult female 30day    2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0026620 expression level Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1263 embryo 04-06hr    2893 embryo 06-08hr    3042 embryo 08-10hr    3028 embryo 10-12hr    3352 embryo 12-14hr    3854 embryo 14-16hr    1772 embryo 16-18hr    1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr    1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6    2856 larva L3 puffstage 7-9    3968 white prepupae new    3586 white prepupae 12hr    3307 white prepupae 24hr    3179 pupae 2d postWPP    3006 pupae 3d postWPP    3730 pupae 4d postWPP    1493 adult male 01day    2714 adult male 05day    2461 adult male 30day    1933 adult female 01day    1696 adult female 05day    2827 adult female 30day    2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr  (1263) embryo 04-06hr  (2893) embryo 06-08hr  (3042) embryo 08-10hr  (3028) embryo 10-12hr  (3352) embryo 12-14hr  (3854) embryo 14-16hr  (1772) embryo 16-18hr  (1900) embryo 18-20hr  (1225) embryo 20-22hr  (1055) embryo 22-24hr  (1494) larva L1  (923) larva L2  (1048) larva L3 12hr old  (973) larva L3 puffstage 1-2  (1360) larva L3 puffstage 3-6  (2856) larva L3 puffstage 7-9  (3968) white prepupae new  (3586) white prepupae 12hr  (3307) white prepupae 24hr  (3179) pupae 2d postWPP  (3006) pupae 3d postWPP  (3730) pupae 4d postWPP  (1493) adult male 01day  (2714) adult male 05day  (2461) adult male 30day  (1933) adult female 01day  (1696) adult female 05day  (2827) adult female 30day  (2416) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr    1263 embryo 04-06hr  (2893) embryo 06-08hr  (3042) embryo 08-10hr  (3028) embryo 10-12hr  (3352) embryo 12-14hr  (3854) embryo 14-16hr  1772 embryo 16-18hr  1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr  1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6  (2856) larva L3 puffstage 7-9  (3968) white prepupae new  (3586) white prepupae 12hr  (3307) white prepupae 24hr  (3179) pupae 2d postWPP  (3006) pupae 3d postWPP  (3730) pupae 4d postWPP  1493 adult male 01day  (2714) adult male 05day  2461 adult male 30day  1933 adult female 01day  1696 adult female 05day  (2827) adult female 30day  2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1263 embryo 04-06hr    2893 embryo 06-08hr    3042 embryo 08-10hr    3028 embryo 10-12hr    3352 embryo 12-14hr    3854 embryo 14-16hr    1772 embryo 16-18hr    1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr    1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6    2856 larva L3 puffstage 7-9    3968 white prepupae new    3586 white prepupae 12hr    3307 white prepupae 24hr    3179 pupae 2d postWPP    3006 pupae 3d postWPP    3730 pupae 4d postWPP    1493 adult male 01day    2714 adult male 05day    2461 adult male 30day    1933 adult female 01day    1696 adult female 05day    2827 adult female 30day    2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1263 embryo 04-06hr    2893 embryo 06-08hr    3042 embryo 08-10hr    3028 embryo 10-12hr    3352 embryo 12-14hr    3854 embryo 14-16hr    1772 embryo 16-18hr    1900 embryo 18-20hr    1225 embryo 20-22hr    1055 embryo 22-24hr    1494 larva L1    923 larva L2    1048 larva L3 12hr old    973 larva L3 puffstage 1-2    1360 larva L3 puffstage 3-6    2856 larva L3 puffstage 7-9    3968 white prepupae new    3586 white prepupae 12hr    3307 white prepupae 24hr    3179 pupae 2d postWPP    3006 pupae 3d postWPP    3730 pupae 4d postWPP    1493 adult male 01day    2714 adult male 05day    2461 adult male 30day    1933 adult female 01day    1696 adult female 05day    2827 adult female 30day    2416 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0026620    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0026620 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval salivary gland, larval trachea, adult ovary, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male reproductive system, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0026620 expression level Tissue   Expression Level Larval Central Nervous System    564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland    537.5 Larval Trachea    568.725 Larval Carcass    672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain    590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary    550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (564.225) Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland  537.5 Larval Trachea  (568.725) Larval Carcass  (672.8) Adult Head    403.4 Adult Eye    391.675 Adult Brain  (590.7) Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary  (550.5) Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland    537.5 Larval Trachea    568.725 Larval Carcass    672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain    590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary    550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland    537.5 Larval Trachea    568.725 Larval Carcass    672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain    590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary    550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0026620 expression level Tissue   Expression Level Larval Central Nervous System    564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland    537.5 Larval Trachea    568.725 Larval Carcass    672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain    590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary    550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland  537.5 Larval Trachea  568.725 Larval Carcass  672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain  590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary  550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland    537.5 Larval Trachea    568.725 Larval Carcass    672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain    590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary    550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    564.225 Larval Midgut    268.4 Larval Hindgut    372.9 Larval Malpighian Tubules    224.5 Larval Fat Body    256.1 Larval Salivary Gland    537.5 Larval Trachea    568.725 Larval Carcass    672.8 Adult Head    403.4 Adult Eye    391.675 Adult Brain    590.7 Adult Thoracic-Abdominal Ganglion    477.7 Adult Crop    300.2 Adult Midgut    290 Adult Hindgut    291.4 Adult Malpighian Tubules    276.1 Adult Fat Body    224.1 Adult Salivary Gland    395.6 Adult Heart    389.575 Adult VirginFemale Spermatheca    219.2 Adult InseminatedFemale Spermatheca    283.6 Adult Ovary    550.5 Adult Testis    236.2 Adult Male Accessory Gland    251.6 Adult Carcass    477 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    403.4   NA  Eye    391.675   NA  Brain    590.7   564.225  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    477.7   NA  Crop    300.2   268.4  Midgut    290   372.9  Hindgut    291.4   224.5  Malpighian Tubules    276.1   256.1  Fat Body    224.1   537.5  Salivary Gland    395.6   NA  Heart    389.575   568.725  Trachea    NA   NA  VirginFemale Spermatheca    219.2   NA  InseminatedFemale Spermatheca    283.6   NA  Ovary    550.5   NA  Testis    236.2   NA  Male Accessory Gland    251.6   672.8  Carcass    477 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_23
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026620 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9765-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage taccstella592 lethal | embryonic stage, with Scer\GAL4mat.αTub67C.T:Hsim\VP16 taccTD.Scer\UAS.P\T.T:Sjap\GST Sterility Allele female sterile tacc1 Other Phenotypes Allele mitotic cell cycle defective taccstella592 wild-type taccUbi-p63E.PG taccUbi-p63E.T:Avic\GFP-m6 Phenotype manifest in Allele aster tacc1 taccUbi-p63E.PG astral microtubule taccS863L.Ubi-p63E.T:Avic\GFP centrosome tacc1 centrosome | ectopic taccstella592 microtubule tacc1 mitotic cell cycle tacc1 nucleus | embryonic stage tacc1 oocyte & spindle (with Df(3R)110) tacc1 pericentriolar material tacc1 pole cell (with Df(3R)110) tacc1 pronucleus tacc1 spindle tacc1 taccUbi-p63E.PG spindle & oocyte taccstella592
Classical Alleles ( 21 )
For All Classical Alleles Show
Allele of tacc Class Mutagen Stocks Known lesion tacc5-SZ-3192 1 -- tacc5-SZ-3472 1 -- taccCB-5315-3 1 -- taccd04158 P-element activity 1 -- taccd04491 1 -- taccd10872 P-element activity 1 -- tacce01011 1 -- taccEY01597b 1 -- taccEY08225 P-element activity 1 -- taccf01914 piggyBac transposase 1 -- taccf05899 piggyBac transposase 1 -- taccNP3204 1 -- taccNP5319 1 -- tacc1 ethyl methanesulfonate 0 -- taccd02911 0 -- taccd03702 P-element activity 0 -- taccd04348 P-element activity 0 -- taccEP341 P-element activity 0 -- taccf03149 piggyBac transposase 0 -- taccNP4484 0 -- taccstella592 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Allele of tacc Class Mutagen Stocks Known lesion taccKK109162 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes taccUbi-p63E.T:Avic\GFP-m6 in vitro construct - regulatory fusion 1 Yes taccGD14304 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes taccKK108100 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes taccS863L.Ubi-p63E.T:Avic\GFP in vitro construct - amino acid replacement 0 Yes taccTD.Scer\UAS.P\T.T:Sjap\GST in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes taccUbi-p63E.PG in vitro construct - regulatory fusion 0 Yes taccUbi-p63E.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes taccUbi-p63E.T:Disc\RFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes taccUbi-p63E.T:Sjap\GST in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)110 (Gergely et al., 2000) Df(3R)Exel6142 (Ryder, 2004.4.26) Df(3R)ME15 (Gergely et al., 2000)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14304} NA P{KK108100} NA P{KK109162} NA P{UASp-tacc.GST-TD} NA characterization construct P{Ubi-GFP-tacc.S863L} NA P{Ubi-GFP-tacc} NA P{Ubi-GST-tacc} NA P{Ubi-tacc.GFP} NA P{Ubi-tacc.RFP} NA P{Ubi-tacc} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}taccEP341 NA P{EPgy2}taccEY01597b NA P{EPgy2}taccEY08225 NA P{XP}taccd02911 NA P{XP}taccd03702 NA P{XP}taccd04158 NA P{XP}taccd04348 NA P{XP}taccd04491 NA P{XP}taccd10872 NA miscellaneous insertions P{}taccstella592 NA P{RS3}taccCB-5315-3 NA P{RS5}tacc5-SZ-3192 NA P{RS5}tacc5-SZ-3472 NA PBac{RB}tacce01011 NA PBac{WH}taccf01914 NA PBac{WH}taccf03149 NA PBac{WH}taccf05899 NA insertion of enhancer trap binary system P{GawB}taccNP3204 No P{GawB}taccNP4484 No P{GawB}taccNP5319 No
Gene Ontology: Function, Process & Cellular Component ( 18 unique terms )
Terms Based on Experimental Evidence ( 10 terms )
Molecular Function
CV term Evidence References
protein binding inferred from physical interaction with msps (Lee et al., 2001)
Biological Process
CV term Evidence References
microtubule cytoskeleton organization inferred from mutant phenotype (Gergely et al., 2000) mitosis inferred from mutant phenotype (Gergely et al., 2000) nuclear migration inferred from mutant phenotype (Gergely et al., 2000) pole cell formation inferred from mutant phenotype (Lerit and Gavis, 2011) pronuclear migration inferred from mutant phenotype (Gergely et al., 2000) protein localization inferred from mutant phenotype (Lee et al., 2001)
Cellular Component
CV term Evidence References
centrosome inferred from direct assay (Gergely et al., 2000, Barros et al., 2005) microtubule associated complex inferred from direct assay (Hughes et al., 2008) spindle pole inferred from direct assay (Meireles et al., 2009)
Terms Based on Predictions or Assertions ( 11 terms )
Molecular Function
CV term Evidence References
microtubule binding traceable author statement (Gergely, 2002)
Biological Process
CV term Evidence References
female meiosis traceable author statement (Gergely, 2002) mitosis non-traceable author statement (Kramer, 1999.4.29) mitotic spindle organization traceable author statement (Gergely, 2002) negative regulation of microtubule depolymerization non-traceable author statement (Raff, 1999.4.29, Gonzalez and Bornens, 2000) traceable author statement (Gergely, 2002) pronuclear fusion traceable author statement (Gergely, 2002, Lee et al., 2001) protein localization traceable author statement (Gergely, 2002)
Cellular Component
CV term Evidence References
astral microtubule traceable author statement (Gergely, 2002) centrosome traceable author statement (Gergely, 2002, Lee et al., 2001) pericentriolar material non-traceable author statement (Gonzalez and Bornens, 2000) spindle microtubule traceable author statement (Gergely, 2002)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions tacc allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65806 DroID - A comprehensive database of gene and protein interactions. • FBgn0026620 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40589
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16093 Dere\GG11411 Dgri\GH17506 Dmoj\GI22520 Dper\GL21486 Dpse\GA22018 Dsec\GM10686 Dsim\GD19661 Dvir\GJ10123 Dwil\GK14428 Dyak\tacc
Curated drosophilid orthologs	Dpse\GA22018   Dyak\tacc
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • XP_394801.3 Apis mellifera (honey bee) 126155 Branchiostoma floridae (lancelet) BGIBMGA004787-PA Bombyx mori (silk worm) ENSBTAP00000014288 Bos taurus (bovine) ENSCPOP00000015048 Cavia porcellus (guinea pig) ENSDARP00000022481 Danio rerio (zebra fish) ENSGACP00000010965 Gymnopilus aculeatus (mushroom) ENSGALP00000025287 Gallus gallus (chicken) ENSMUSP00000110069 Mus musculus (house mouse) XP_001599707.1 Nasonia vitripennis (wasp) ENSOANP00000012137 Ornithorynchus anatinus (platypus) ENSORLP00000020987 Oryzias latipes (japanese killifish) PHUM007293-PA Pediculus humanus (human body louse) 61433 Trichoplax adhaerens (metazoa) ENSTNIP00000019728 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000022093 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15755 NV18077 LH16642 ISCW017142 FBgn0067922 FBgn0216434 FBgn0197411 FBgn0191152 FBgn0165632 JGI_V11_304681 FBgn0247667 FBgn0159079 FBgn0145248 FBgn0124976 FBgn0103711 FBgn0093115 CPIJ007378 BGIBMGA005040 BGIBMGA005038 BGIBMGA004787 ACYPI006083 GB13497 AGAP010297 PHUM467120 GLEAN_13569
Stocks & Reagents
Stocks Listed in FlyBase ( 15 )
Bloomington	7066 P{Ubi-tacc.GFP}1, y1 w*
Harvard	- P{XP}taccd04158 - P{XP}taccd04491 - P{XP}taccd10872 - PBac{RB}tacce01011 - PBac{WH}taccf01914 - PBac{WH}taccf05899
Kyoto	104411 w*; P{GawB}taccNP3204 123563 w1118; P{RS3}taccCB-5315-3 125939 w1118; P{RS5}tacc5-SZ-3192 126081 w1118; P{RS5}tacc5-SZ-3472
VDRC	v101439 P{KK109162}VIE-260B
	More stocks available...
Genomic Clones ( 1 )
	BACR02C19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 123 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT30379 LD15470
Other clones	LD14115 MIP19445
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT10088 AT23573 AT28057 GH07311 GH14396 GH19268 GH28083 RE04273 RE07321 RE22271 RE40322 RE42718 RE58452 RE66308 SD08089 SD22310
Other clones	7771 9160 9544 12198 19079 29467 36575 39247 43094 53872 54693 56507 62689 63868 64753 70276 97372 99846 106867 108692 119470 148752 179642 214277.65 214277.68 214347.65 523451 CK01.64B.G4 CK01.74A.E11 CK01.79B.E1 CK01.79D.G12 CK01.86A.E3 CK01.100C.E6 CK01.133B.A6 Dmel_neb_008753_0626_2204 Dmel_neb_015478_0650_0661 EC13638 EC40209 EK052244 EK058318 EK061617 EK065058 EK068018 EK084951 EK085406 EK101935 EK102002 EK106157 EK107823 EK108423 EK112952 EK132132 EK135601 EK137240 EK147347 EK156215 EK164926 EK169159 EK171632 EK172564 EK174228 EK178021 EK180717 EK183702 EK188419 EK190719 EK190909 EK192933 EK206202 EK222263 EK225704 EK233907 EK235112 EK239155 EK242709 EK255246 EK265808 EK284412 EN03938 EP02039 EP03657 EP05049 GM03685 RP004010032 RP004033356 RP004036005 RP004199025 RP004222011 RP004225893 RP004230022 RP004269070 RP004325203 RP004434492 RP004484073 RP004485394 RP004486272 RP004496856 RP004509660 RP004517883 RP004527694 RP004535302 RP004538962 SD07434
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0026620 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40589
Antibody Information
	polyclonal (Gergely et al., 2000, Giet et al., 2002, Kao and Megraw, 2009)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	sub mutants do not interact with alleles of γTub37C, αTub67C, msps, tacc or wisp. (Giunta et al., 2002) tacc is essential for mitotic spindle function in the early embryo. (Gergely et al., 2000)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_058085 NM_058086 NM_169016 NM_176401 NM_176402 NM_176403 NM_176404 NM_001202238 NM_001202239 NM_001202240 RefSeq (Proteins) • NP_477433 NP_477434 NP_730867 NP_788578 NP_788579 NP_788580 NP_788581 NP_001189167 NP_001189168 NP_001189169 DDBJ / EMBL / GenBank • AA440629 AAD30171 AAF52099 AAF66735 AAL13728 AAN13287 AAN13288 AAO41502 AAO41503 AAO41504 AAO41505 AAY82186 AAY82187 AC008189 ADV37259 ADV37260 ADV37261 AF146700 AF146756 AQ025066 AW942358 AY058499 CL528090 CZ473513 CZ473764 CZ473880 CZ473881 CZ477479 CZ484410 CZ484411 CZ485696 CZ488522 CZ488523 DQ017404 DQ017405 Entrez Gene - A searchable database of RefSeq genes. • 40589 UniProtKB/TrEMBL • Q3YNE8 Q8IPN1 Q9NJH5 Q9VN51 Q9XZL7 Q86BB4 Q86BB5 Q95TU9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Transforming acidic coiled-coil (IPR007707)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65806 DroID - A comprehensive database of gene and protein interactions. • FBgn0026620 DRSC - Results from RNAi screens. • FBgn0026620 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026620 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9765-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0026620 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40589 InParanoid A subset of ortholog calls from InParanoid. • XP_394801.3 Apis mellifera (honey bee) 126155 Branchiostoma floridae (lancelet) BGIBMGA004787-PA Bombyx mori (silk worm) ENSBTAP00000014288 Bos taurus (bovine) ENSCPOP00000015048 Cavia porcellus (guinea pig) ENSDARP00000022481 Danio rerio (zebra fish) ENSGACP00000010965 Gymnopilus aculeatus (mushroom) ENSGALP00000025287 Gallus gallus (chicken) ENSMUSP00000110069 Mus musculus (house mouse) XP_001599707.1 Nasonia vitripennis (wasp) ENSOANP00000012137 Ornithorynchus anatinus (platypus) ENSORLP00000020987 Oryzias latipes (japanese killifish) PHUM007293-PA Pediculus humanus (human body louse) 61433 Trichoplax adhaerens (metazoa) ENSTNIP00000019728 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000022093 Takifugu rubripes (pufferfish Takifugu) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/tacc.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40589 modMine - Data generated by the modENCODE project. • FBgn0026620 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15755 NV18077 LH16642 ISCW017142 FBgn0067922 FBgn0216434 FBgn0197411 FBgn0191152 FBgn0165632 JGI_V11_304681 FBgn0247667 FBgn0159079 FBgn0145248 FBgn0124976 FBgn0103711 FBgn0093115 CPIJ007378 BGIBMGA005040 BGIBMGA005038 BGIBMGA004787 ACYPI006083 GB13497 AGAP010297 PHUM467120 GLEAN_13569
Synonyms & Secondary IDs ( 16 )
Reported As
Symbol Synonym	acc (Coulier et al., 2000) CG9765 (Keleman et al., 2009.8.5, Hughes et al., 2008) D-TACC (Brittle, 2005, Martinez-Campos et al., 2004, Brittle and Ohkura, 2005, Fischer et al., 2004, Gonzalez and Bornens, 2000, Kramer and Hawley, 2003, Ohkura et al., 2001, Ohkura, 2001, Scholey et al., 2001, Wells, 2001, de Carcer et al., 2001, Bolivar et al., 2001, Kramer et al., 2001, Gergely et al., 1999, Gergely et al., 2000, Cullen and Ohkura, 2005, Basto et al., 2006, Garcia et al., 2007, Barros et al., 2005, Cullen et al., 2005, Mottier et al., 2008, Megraw et al., 2008, Hutterer et al., 2006, Blagden and Glover, 2003, Lucas and Raff, 2007, Zhang and Megraw, 2007, Hughes et al., 2008, Pandey et al., 2007, Basto et al., 2007, Meireles et al., 2009, Ducat et al., 2008, Colombié et al., 2008, Pearson et al., 2005, Bucciarelli et al., 2009, Conduit et al., 2010, Kao and Megraw, 2009, Hughes et al., 2011, Wang et al., 2011) d-tacc (Moon and Hazelrigg, 2004, Kwon and Scholey, 2004, Giet et al., 2002, Theurkauf, 2001, Lee et al., 2001, Cullen and Ohkura, 2001, Gergely, 2002, McKim et al., 2002, Lee et al., 2001, Giunta et al., 2002, Cullen et al., 2005, Barros et al., 2005, Cullen et al., 2005, Giansanti et al., 2008) dtacc (Raff, 2002, Lerit and Gavis, 2011) D-tacc (Kramer et al., 2004) DTACC (Stevenson et al., 2001, Martins et al., 2007, Zhang et al., 2009) dTACC (Hafer and Schedl, 2003, Tan et al., 2007, Tan et al., 2008, Still et al., 2004) TACC (Gergely et al., 2000, Jang et al., 2007, Pandey et al., 2007, McCleland et al., 2009, Anderson et al., 2009, Wen et al., 2008, Moshkin et al., 2009, Kao and Megraw, 2009, Ma and Jarman, 2011) tacc (Mukai et al., 2006, Jang et al., 2005, McCleland and O'Farrell, 2008, Lucas and Raff, 2007) TACCdm (Still et al., 2004)
Name Synonym	D. melanogaster transforming acidic coiled coil (Meireles et al., 2009) Drosophila transforming acidic coiled-coil (Tan et al., 2008) Drosophila Transforming Acidic Coiled-Coil protein (Tan et al., 2007) transforming acidic coiled-coil (McCleland et al., 2009) transforming acidic coiled-coil protein (Kramer, 1999.4.29, Mukai et al., 2006)
Secondary FlyBase IDs
References ( 89 )
Generate a list of	All references relating to this gene ( 89 )
List References by type	Research paper  ( 49 ) Supplementary material  ( 3 ) Review  ( 10 ) Personal communication to FlyBase  ( 2 ) Abstract  ( 14 ) FlyBase analysis  ( 3 ) Conference report  ( 2 ) DNA/RNA sequence record  ( 2 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 5 )
	Hughes et al., 2011, PLoS Genet. 7(8): e1002209 Gamma-Tubulin Is Required for Bipolar Spindle Assembly and for Proper Kinetochore Microtubule Attachments during Prometaphase I in Drosophila Oocytes. [FBrf0214729] Lerit and Gavis, 2011, Curr. Biol. 21(6): 439--448 Transport of germ plasm on astral microtubules directs germ cell development in Drosophila. [FBrf0213255] Ma and Jarman, 2011, J. Cell Sci. 124(15): 2622--2630 Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation. [FBrf0214370] Wang et al., 2011, PLoS Genet. 7(8): e1002227 PP2A-Twins Is Antagonized by Greatwall and Collaborates with Polo for Cell Cycle Progression and Centrosome Attachment to Nuclei in Drosophila Embryos. [FBrf0214683] Conduit et al., 2010, Curr. Biol. 20(24): 2178--2186 Centrioles Regulate Centrosome Size by Controlling the Rate of Cnn Incorporation into the PCM. [FBrf0212603] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...