D-TACC, dTACC
centrosomal protein that stabilizes microtubules during mitosis by recruiting the microtubule plus end binding protein Minispindles
Please see the GBrowse view of Dmel\tacc or the JBrowse view of Dmel\tacc for information on other features
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Gene model reviewed during 5.45
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
4.626 (longest cDNA)
1190 (aa); 220 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tacc using the Feature Mapper tool.
Staining of embryos with antibodies against tacc reveals strong staining of the centrosomes and weak staining of the spindle microtubules.
Protein was highly concentrated at centrosomes throughout the cell cycle and low levels of staining were observed in astral microtubules and spindle microtubules.
GBrowse - Visual display of RNA-Seq signals
View Dmel\tacc in GBrowse 23-47.1
3-47.1
3-44.1
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
tacc is essential for mitotic spindle function in the early embryo.
