General Information Symbol Dmel\ fu12Species D. melanogaster Name fu12 Annotation symbol CG17608 Feature type protein_coding_gene FlyBase ID FBgn0026718 Gene Model Status Current Stock availability 8 publicly
available Genomic Location Chromosome (arm) 2L Recombination map Cytogenetic map 29C5-29D1 Sequence location 2L:8,449,691..8,463,994 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
fu12 is referred to in FlyBase by the symbol
Dmel\fu12 (CG17608, FBgn0026718). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : 1-acylglycerol-3-phosphate O-acyltransferase activity. There is experimental evidence that it is involved in the
biological process : behavioral response to ethanol.
9 alleles are reported . No phenotypic data is available. It has
4 annotated transcripts and
4 annotated polypeptides .
Protein features are: 1-acyl-sn-glycerol-3-phosphate acyltransferase; Phospholipid/glycerol acyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut, virgin spermatheca, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, larval midgut, adult hindgut, adult Malpighian tubules, adult fat body, adult female reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625344_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of fu12. Gene sequence location is
2L:8449691..8463994 .
User Contributed Data
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FB2013_03
FB2013_02
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
(542.6)
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
(542.8)
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
122.025
Larval Midgut
256.1
Larval Hindgut
54
Larval Malpighian Tubules
49.6
Larval Fat Body
94.3
Larval Salivary Gland
12.4
Larval Trachea
37.65
Larval Carcass
11.075
Adult Head
173.6
Adult Eye
99.475
Adult Brain
101.5
Adult Thoracic-Abdominal Ganglion
131.5
Adult Crop
92.2
Adult Midgut
542.6
Adult Hindgut
139.4
Adult Malpighian Tubules
416.3
Adult Fat Body
254.8
Adult Salivary Gland
33.3
Adult Heart
61.75
Adult VirginFemale Spermatheca
542.8
Adult InseminatedFemale Spermatheca
309.1
Adult Ovary
262.7
Adult Testis
511.9
Adult Male Accessory Gland
12.2
Adult Carcass
145.4
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
173.6
NA
Eye
99.475
NA
Brain
101.5
122.025
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
131.5
NA
Crop
92.2
256.1
Midgut
542.6
54
Hindgut
139.4
49.6
Malpighian Tubules
416.3
94.3
Fat Body
254.8
no informative data
Salivary Gland
no informative data
NA
Heart
61.75
37.65
Trachea
NA
NA
VirginFemale Spermatheca
542.8
NA
InseminatedFemale Spermatheca
309.1
NA
Ovary
262.7
NA
Testis
511.9
NA
Male Accessory Gland
no informative data
no informative data
Carcass
145.4
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
42
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
42
ovary, mated 4-day female
37
testis, mated 4-day male
68
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
(42)
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
(42)
ovary, mated 4-day female
(37)
testis, mated 4-day male
(68)
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
42
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
42
ovary, mated 4-day female
37
testis, mated 4-day male
68
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
42
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
42
ovary, mated 4-day female
37
testis, mated 4-day male
68
accessory gland, mated 4-day male
5
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
42
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
42
ovary, mated 4-day female
37
testis, mated 4-day male
68
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
(42)
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
(42)
ovary, mated 4-day female
(37)
testis, mated 4-day male
(68)
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
42
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
42
ovary, mated 4-day female
37
testis, mated 4-day male
68
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
17
central nervous system, larvae L3
4
central nervous system, pupae P8
4
head, virgin 1-day female
5
head, virgin 4-day female
7
head, virgin 20-day female
7
head, mated 1-day female
7
head, mated 4-day female
7
head, mated 20-day female
8
head, mated 1-day male
3
head, mated 4-day male
9
head, mated 20-day male
15
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
3
digestive system, larvae L3 wandering
42
digestive system, 1-day adult
22
digestive system, 4-day adult
15
digestive system, 20-day adult
17
fat body, larvae L3 wandering
10
fat body, white prepupae
5
fat body, pupae P8
2
carcass, larvae L3 wandering
2
carcass, 1-day adult
9
carcass, 4-day adult
10
carcass, 20-day adult
10
ovary, virgin 4-day female
42
ovary, mated 4-day female
37
testis, mated 4-day male
68
accessory gland, mated 4-day male
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
36
white prepupae new
64
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
(36)
white prepupae new
(64)
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
36
white prepupae new
64
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
36
white prepupae new
64
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
36
white prepupae new
64
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
(36)
white prepupae new
(64)
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
36
white prepupae new
64
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
19
embryo 02-04hr
4
embryo 04-06hr
1
embryo 06-08hr
1
embryo 08-10hr
3
embryo 10-12hr
8
embryo 12-14hr
10
embryo 14-16hr
8
embryo 16-18hr
8
embryo 18-20hr
7
embryo 20-22hr
19
embryo 22-24hr
24
larva L1
22
larva L2
17
larva L3 12hr old
15
larva L3 puffstage 1-2
11
larva L3 puffstage 3-6
14
larva L3 puffstage 7-9
36
white prepupae new
64
white prepupae 12hr
10
white prepupae 24hr
14
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
11
adult male 01day
18
adult male 05day
23
adult male 30day
22
adult female 01day
10
adult female 05day
21
adult female 30day
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
50
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
61
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
35
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
(50)
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
(61)
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
(35)
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
50
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
61
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
35
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
50
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
61
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
35
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
50
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
61
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
35
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
(50)
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
(61)
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
(35)
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
50
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
61
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
35
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
2
Schneider line 2 Sg4
11
embryonic 1182-4H
0
embryonic GM2
50
embryonic Kc167
8
embryonic S1
1
embryonic S3
6
leg disc CME L1
11
wing disc CME-W2
0
wing disc ML-DmD8
5
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
61
wing disc ML-DmD21
0
wing disc ML-DmD32
1
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
16
mixed discs ML-DmD4-c1
35
CNS ML-DmBG1-c1
1
CNS ML-DmBG2-c2
2
tumorous blood cells mbn2
2
ovary fGS/OSS
13
ovary OSC
4
ovary OSS
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
(27)
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
7
heat shock, 4-day adult
15
Cadmium 50 mM 6 hrs, larvae L3
14
Cadmium 50 mM 12 hrs, larvae L3
25
Cadmium 50 mM 48 hrs, 4-day adult
12
Cadmium 100 mM 48 hrs, 4-day adult
27
Copper 0.5 mM 12 hrs, larvae L3
9
Copper 15 mM 48 hrs, 4-day adult
21
Zinc 5 mM 12 hrs, larvae L3
6
Zinc 4.5 mM 48 hrs, 4-day adult
19
Ethanol 2.5% 3 hrs, larvae L3
25
Ethanol 5% 3 hrs, larvae L3
13
Ethanol 10% 3 hrs, larvae L3
10
Caffeine 1.5 mg/ml 4 hrs, larvae L3
12
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
20
Caffeine 25 mg/ml 48 hrs, 4-day adult
16
Paraquat 5 mM 48 hrs, 4-day adult
22
Paraquat 10 mM 48 hrs, 4-day adult
22
Rotenone 2 μg 12 hrs, larvae L3
15
Rotenone 8 μg 12 hrs, larvae L3
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 7 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 2 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
insertion of enhancer trap binary system
Gene Ontology: Function, Process
& Cellular Component ( 4 unique terms ) Terms Based on
Experimental Evidence ( 1 term ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function inferred from sequence or structural similarity with
EMBL:AF030001 non-traceable author statement
Biological Process Cellular Component Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (70)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG63JCQV )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6MSD73 )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6K3JSJ )
Apis mellifera
Western honey bee
Amel\GB43360
Y
Apis mellifera
Western honey bee
Amel\LOC552139
Y
Apis mellifera
Western honey bee
Amel\GB43362
Y
Apis mellifera
Western honey bee
Amel\GB43358
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG009854
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011292
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG003682
Y
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH19374
Y
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH23685
Y
Atta cephalotes
Leafcutter ant
Acep\ACEP12512
Y
Atta cephalotes
Leafcutter ant
Acep\ACEP26843
Y
Atta cephalotes
Leafcutter ant
Acep\ACEP12513
Y
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO18085
Y
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO15174
Y
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL13184
Y
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL23472
Y
Linepithema humile
Argentine ant
Lhum\LH13422
Y
Linepithema humile
Argentine ant
Lhum\LH21494
Y
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB18823
Y
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB14353
Y
Solenopsis invicta
Red fire ant
Sinv\SINV15462
Y
Solenopsis invicta
Red fire ant
Sinv\SINV11128
Y
Acyrthosiphon pisum
Pea aphid
Y
Pediculus humanus
Human body louse
Y
Pediculus humanus
Human body louse
Y
Tribolium castaneum
Red flour beetle
Y
Tribolium castaneum
Red flour beetle
Y
Orthologs in non-Insect Arthropods
(EOG631ZF8 )
Daphnia pulex
Water flea
Y
Ixodes scapularis
Deer tick
Y
Ixodes scapularis
Deer tick
Y
Orthologs in non-Arthropod Metazoa
(EOG66QKMV )
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (2)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 8 )Bloomington Harvard Kyoto VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 124 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 3 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 29 )Generate a list of List References by type
Recent research papers ( 1 )
Tian et al., 2011, PLoS Genet. 7(4): e1001364Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. [FBrf0213596]