FlyBase Gene Report: Dmel\drosha

General Information

Symbol

Dmel\drosha

Species

D. melanogaster

Name

drosha

Annotation Symbol

CG8730

Feature Type

protein_coding_gene

FlyBase ID

FBgn0026722

Gene Model Status

Stock Availability

5 publicly available

Gene Summary

drosha (drosha) encodes a protein that contributes to miRNA processing. It is involved in salivary gland histolysis and oocyte development. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:7,932,429..7,936,840 [+]

Recombination map

2-57

RefSeq locus

NT_033778 REGION:7932429..7936840

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (13 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables double-stranded RNA binding

inferred from sequence or structural similarity

(Lasko, 2000)

inferred from biological aspect of ancestor with PANTHER:PTN000129453

(assigned by GO_Central )

(Gaudet et al., 2011)

enables ribonuclease III activity

inferred from biological aspect of ancestor with PANTHER:PTN000129453

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (9 terms)

Terms Based on Experimental Evidence (6 terms)

CV Term

Evidence

References

involved_in germarium-derived female germ-line cyst formation

inferred from mutant phenotype

(Azzam et al., 2012)

involved_in germarium-derived oocyte fate determination

inferred from mutant phenotype

(Azzam et al., 2012)

involved_in mushroom body development

inferred from mutant phenotype

(Luhur et al., 2014)

involved_in pre-miRNA processing

inferred from mutant phenotype

(Mugat et al., 2015)

involved_in primary miRNA processing

inferred from mutant phenotype

(Smibert et al., 2011, Landthaler et al., 2004)

involved_in salivary gland histolysis

inferred from mutant phenotype

(Nelson et al., 2014)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

involved_in pre-miRNA processing

inferred from biological aspect of ancestor with PANTHER:PTN000129454

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in primary miRNA processing

inferred from biological aspect of ancestor with PANTHER:PTN000129454

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in production of siRNA involved in RNA interference

inferred from biological aspect of ancestor with PANTHER:PTN000129454

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in RNA processing

inferred from biological aspect of ancestor with PANTHER:PTN000129453

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in rRNA catabolic process

inferred from electronic annotation with InterPro:IPR011907

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

part_of microprocessor complex

inferred from direct assay

(Mugat et al., 2015)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

located_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000129454

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

RIBONUCLEASES III

Protein Family (UniProt)

-

Protein Signatures (InterPro)

Summaries

Gene Snapshot

drosha (drosha) encodes a protein that contributes to miRNA processing. It is involved in salivary gland histolysis and oocyte development. [Date last reviewed: 2019-09-19]

Gene Group (FlyBase)

RIBONUCLEASES III -: Ribonucleases III catalyze the endonucleolytic cleavage of RNA to generate 5'-phosphomonoesters and 3'-OH termini, by recognizing double-stranded RNA followed by two staggered cuts.

Summary (Interactive Fly)

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\drosha for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.49

Sequence Ontology: Class of Gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0088850

4290

1327

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

FBpp0087926

152.8

1327

7.35

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\drosha using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

drosha_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

part_of microprocessor complex

inferred from direct assay

(Mugat et al., 2015)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\drosha in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\drosha

View exonic expression by tissue for Dmel\drosha

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0026722

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG8730-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8730

Flygut - An atlas of the Drosophila adult midgut

FBgn0026722

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 8 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 14 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of drosha

Transgenic constructs containing regulatory region of drosha

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

(Smibert et al., 2011, Ryder, 2004.4.26)

Inferred from location ( 0 )

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | embryonic stage (with drosha^Q884X)

drosha^W1123X

lethal | embryonic stage (with drosha^W1123X)

drosha^Q884X

lethal | larval stage (with drosha^Q884X)

drosha^W1123X

lethal | larval stage (with drosha^W1123X)

drosha^Q884X

lethal | pupal stage (with drosha^Q884X)

drosha^W1123X

lethal | pupal stage (with drosha^W1123X)

drosha^Q884X

lethal | recessive

lethal - all die before end of P-stage (with Df(2R)Exel6055)

drosha^15N1

partially lethal, with Scer\GAL4^tin.CΔ4

drosha^GD13784

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

drosha^GD13784

viable, with Scer\GAL4^Mef2.PR

drosha^GD13784

viable, with Scer\GAL4^pnr-MD237

drosha^GD13784

Other Phenotypes

Allele

abnormal neuroanatomy

drosha^ΔE859K

abnormal neuroanatomy, with Scer\GAL4^ey-OK107

abnormal neuroanatomy | larval stage

drosha^GD13784

abnormal neurophysiology | adult stage | somatic clone

drosha^15N1

majority die during larval stage (with Df(2R)Exel6055)

drosha^R1113X

majority die during prepupal stage (with Df(2R)Exel6055)

some die during pharate adult stage (with Df(2R)Exel6055)

drosha^15N1

visible, with Scer\GAL4^nub-AC-62

drosha^HMS00064

visible, with Scer\GAL4^pnr-MD237

drosha^GD13784

visible | somatic clone

Phenotype manifest in

Allele

adult antennal lobe projection neuron adPN | somatic clone

drosha^21K11

adult antennal lobe projection neuron DL1 adPN | somatic clone

drosha^ΔE859K

adult mushroom body gamma-lobe

drosha^ΔE859K

alpha/beta Kenyon cell | somatic clone

drosha^21K11

alpha'/beta' Kenyon cell, with Scer\GAL4^ey-OK107

alpha'/beta' Kenyon cell | somatic clone

drosha^21K11

embryonic/larval central nervous system (with Df(2R)Exel6055)

eye | somatic clone

eye disc | third instar larval stage

drosha^6M1

gamma Kenyon cell | somatic clone

drosha^21K11

imaginal disc (with Df(2R)Exel6055)

imaginal disc | third instar larval stage

larval neuroblast | larval stage

drosha^GD13784

mesothoracic tergum, with Scer\GAL4^pnr-MD237

drosha^GD13784

mushroom body | somatic clone

drosha^21K11

oocyte | germline clone

drosha^21K11

salivary gland | pupal stage, with Scer\GAL4^fkh.PU

drosha^{dsRNA.UAS.cUa}

trichogen cell, with Scer\GAL4^pnr-MD237

drosha^GD13784

wing, with Scer\GAL4^nub-AC-62

drosha^HMS00064

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

14 of 15

Yes

Yes

1 of 15

No

No

1 of 15

No

No

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

14 of 15

Yes

Yes

1 of 15

No

No

1 of 15

No

No

Rattus norvegicus (Norway rat) (3)

13 of 13

Yes

Yes

1 of 13

No

No

1 of 13

No

No

Xenopus tropicalis (Western clawed frog) (3)

8 of 12

Yes

Yes

1 of 12

No

No

1 of 12

No

No

Danio rerio (Zebrafish) (4)

10 of 15

Yes

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Caenorhabditis elegans (Nematode, roundworm) (2)

14 of 15

Yes

Yes

1 of 15

No

No

Arabidopsis thaliana (thale-cress) (7)

2 of 9

Yes

Yes

1 of 9

No

Yes

1 of 9

No

No

1 of 9

No

Yes

1 of 9

No

Yes

1 of 9

No

Yes

1 of 9

No

Yes

Saccharomyces cerevisiae (Brewer's yeast) (2)

7 of 15

Yes

Yes

2 of 15

No

No

Schizosaccharomyces pombe (Fission yeast) (2)

5 of 12

Yes

Yes

1 of 12

No

No

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091900SI )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00006679

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Drosophila persimilis

Drosophila willistoni

Drosophila virilis

Drosophila mojavensis

Drosophila grimshawi

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500ZL )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Glossina morsitans

Tsetse fly

Gmor\GMOY008669

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_10219

Mayetiola destructor

Hessian fly

Mdes\Mdes002849

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008592

Anopheles darlingi

American malaria mosquito

Adar\ADAC002334

Anopheles gambiae

Malaria mosquito

Agam\AGAP008087

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ001734

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0103 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Danaus plexippus

Monarch butterfly

Dple\DPOGS206644-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL011141

Apis florea

Little honeybee

Aflo\3251671876

Apis mellifera

Western honey bee

Bombus impatiens

Common eastern bumble bee

Bombus terrestris

Buff-tailed bumblebee

Linepithema humile

Argentine ant

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:000363

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG019932

Dendroctonus ponderosae

Mountain pine beetle

Dendroctonus ponderosae

Mountain pine beetle

Tribolium castaneum

Red flour beetle

Pediculus humanus

Human body louse

Phum\PHUM524860

Rhodnius prolixus

Kissing bug

Rpro\RPRC013112

Cimex lectularius

Bed bug

Clec\CLEC025177

Cimex lectularius

Bed bug

Clec\CLEC011511

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI001907

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_12973

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X00YB )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR002320

Ixodes scapularis

Black-legged tick

Isca\ISCW023600

Stegodyphus mimosarum

African social velvet spider

Smim\KFM76178.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur12g00910

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_442

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02A9 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Rnase3l_1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Rnase3l

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000001525

Gallus gallus

Domestic chicken

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (3)

Gene Symbol

Score

Source

Alignment

2 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

DROSHA; drosha ribonuclease III

14 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

RNA-protein

Physical Interaction

Assay

References

drosha - mir-ban

enzymatic study, northern blot

(Denli et al., 2004)

protein-protein

Physical Interaction

Assay

References

anti tag coimmunoprecipitation, anti tag western blot

(Luhur et al., 2014)

anti tag coimmunoprecipitation, anti tag western blot, western blot, ion exchange chromatography, molecular sieving, anti bait coimmunoprecipitation

(Mugat et al., 2015, Xiong et al., 2015, Luhur et al., 2014, Denli et al., 2004)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Smibert et al., 2011)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

61611

DroID - A comprehensive database of gene and protein interactions.

FBgn0026722

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

35747

MIST (protein-protein) - An integrated Molecular Interaction Database

drosha

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Ribosome biogenesis in eukaryotes

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2R

Recombination map

2-57

Cytogenetic map

Sequence location

2R:7,932,429..7,936,840 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

43F2-43F3

Limits computationally determined from genome sequence between P{lacW}lin19^k01207&P{lacW}rnh1^k07624 and P{lacW}CSN4^k08018&P{lacW}l(2)k08504^k08504

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-57

(FlyBase, 2016)

2-57.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

27704

y¹ v¹; P{TRiP.JF02784}attP2

35233

y¹ sc^* v¹ sev²¹; P{TRiP.GL00118}attP2

33657

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00064}attP2/TM3, Sb¹

v108026

P{KK105813}VIE-260B

v23772

w¹¹¹⁸; P{GD13784}v23772

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (54)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0026722

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0026722

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35747

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Na et al., 2016)

polyclonal

(Denli et al., 2004)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Additional comments

Other Comments

drosha is required for the production of later born α/β and α/β neurons and suggests that drosha processing of RNAs in addition to let-7 and mir-125 promotes neuroblast maintenance.

(Luhur et al., 2014)

RNAi knockdown of drosha function in S2 cells results in an accumulation of pri-miRNAs and a reduction of pre-miRNAs and mature miRNAs.

(Landthaler et al., 2004)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 37 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35747

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0026722

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

drosha_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8730

Flygut - An atlas of the Drosophila adult midgut

FBgn0026722

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35747

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG8730

modMine - A data warehouse for the modENCODE project

FBgn0026722

Linkouts

BioGRID - A database of protein and genetic interactions.

61611

DroID - A comprehensive database of gene and protein interactions.

FBgn0026722

DRSC - Results frm RNAi screens

FBgn0026722

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0026722

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG8730-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0026722

FlyMine - An integrated database for Drosophila genomics

FBgn0026722

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

35747

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Ribosome biogenesis in eukaryotes

MIST (protein-protein) - An integrated Molecular Interaction Database

drosha

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG8730

(Na et al., 2016, Hosono et al., 2015, Ding et al., 2014, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009)

DROSHA

(Kolaczkowski et al., 2011)

Drosha

(Schneider and Imler, 2021, Liu et al., 2019, Swevers et al., 2018, Yamashiro and Siomi, 2018, Azlan et al., 2016, Brewer-Jensen et al., 2016, Truscott et al., 2016, Yang et al., 2016, Chak et al., 2015, Mugat et al., 2015, Xiong et al., 2015, Barrio et al., 2014, Chawla and Sokol, 2014, Luhur et al., 2014, Carré et al., 2013, Hu et al., 2013, Meister, 2013, Okamura et al., 2013, Sabin et al., 2013, Xiong et al., 2013, Pressman et al., 2012, Pushpavalli et al., 2012, Westholm et al., 2012, Liu et al., 2011, Ni et al., 2011, Qian et al., 2011, Flynt et al., 2010, Swami, 2010, Hartig et al., 2009, Hu et al., 2009, Hwang et al., 2009, Okamura et al., 2009, Zhou et al., 2009, Chung et al., 2008, Kawamura et al., 2008, Okamura et al., 2008, Okamura et al., 2008, Zhou et al., 2008, Eulalio et al., 2007, Okamura et al., 2007, Yu et al., 2007, Dorner et al., 2006, Valencia-Sanchez et al., 2006, Pearson et al., 2005, Denli et al., 2004)

drosha

(Liu et al., 2019, Xie et al., 2019, Mohorianu et al., 2018, Gerstberger et al., 2017, Funikov et al., 2016, Na et al., 2016, Sanfilippo et al., 2016, Faisal et al., 2014, Nelson et al., 2014, Smibert et al., 2013, Azzam et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Lindquist et al., 2011, Smibert et al., 2011, Czech et al., 2009, Förstemann et al., 2007, Ruby et al., 2007, Ruby et al., 2007, Han et al., 2006)

Name Synonyms

Drosha

(Xiong et al., 2016, Besnard-Guérin et al., 2015, Lucas et al., 2015, Sabin et al., 2009, Czech et al., 2008, Jacquier et al., 2008, Eulalio et al., 2007, Yu et al., 2007, Rehwinkel et al., 2006, Denli et al., 2004, Schmittgen et al., 2004)

drosha

(Faisal et al., 2014, Kadener et al., 2009, Kadener et al., 2009)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (137)