FB2019_05, released Oct 15, 2019

Gene: Dmel\drosha

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General Information
Symbol
Dmel\drosha
Species
D. melanogaster
Name
drosha
Annotation Symbol
CG8730
Feature Type
protein_coding_gene
FlyBase ID
FBgn0026722
Gene Model Status
Current
Stock Availability
5 publicly available
Enzyme Name (EC)
Ribonuclease III (3.1.26.3)
Gene Snapshot
drosha (drosha) encodes a protein that contributes to miRNA processing. It is involved in salivary gland histolysis and oocyte development. [Date last reviewed: 2019-09-19]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
43F2-43F3
Sequence location
2R:7,932,429..7,936,840 [+]
Recombination map
2-57
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
-
Predictions / Assertions
double-stranded RNA binding; ribonuclease III activity
Catalytic Activity (EC)
Experimental Evidence
-
Predictions / Assertions
Endonucleolytic cleavage to 5'-phosphomonoester (3.1.26.3)
Summaries
Summary (Interactive Fly)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\drosha or the JBrowse view of Dmel\drosha for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.49
Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
drosha-RA
FBtr0088850
NM_058088
4290
1327
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
drosha-PA
FBpp0087926
152.8
1327
7.35
NP_477436
AAF59169
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\drosha using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (12 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
double-stranded RNA binding
inferred from sequence or structural similarity
(Lasko, 2000)
inferred from biological aspect of ancestor with PANTHER:PTN000129453
(assigned by GO_Central )
(Gaudet et al., 2011)
ribonuclease III activity
inferred from biological aspect of ancestor with PANTHER:PTN000129453
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (9 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
germarium-derived female germ-line cyst formation
inferred from mutant phenotype
(Azzam et al., 2012)
germarium-derived oocyte fate determination
inferred from mutant phenotype
(Azzam et al., 2012)
mushroom body development
inferred from mutant phenotype
(Luhur et al., 2014)
primary miRNA processing
inferred from mutant phenotype
(Smibert et al., 2011, Landthaler et al., 2004)
salivary gland histolysis
inferred from mutant phenotype
(Nelson et al., 2014)
Terms Based on Predictions or Assertions (5 terms)
CV Term
Evidence
References
pre-miRNA processing
inferred from biological aspect of ancestor with PANTHER:PTN000129454
(assigned by GO_Central )
(Gaudet et al., 2011)
primary miRNA processing
inferred from biological aspect of ancestor with PANTHER:PTN000129454
(assigned by GO_Central )
(Gaudet et al., 2011)
production of siRNA involved in RNA interference
inferred from biological aspect of ancestor with PANTHER:PTN000129454
(assigned by GO_Central )
(Gaudet et al., 2011)
RNA processing
inferred from biological aspect of ancestor with PANTHER:PTN000129453
(assigned by GO_Central )
(Gaudet et al., 2011)
rRNA catabolic process
inferred from electronic annotation with InterPro:IPR011907
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
nucleus
inferred from biological aspect of ancestor with PANTHER:PTN000129454
(assigned by GO_Central )
(Gaudet et al., 2011)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\drosha in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 8 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 14 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of drosha
Transgenic constructs containing regulatory region of drosha
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal | embryonic stage (with droshaQ884X)
lethal | embryonic stage (with droshaW1123X)
lethal | larval stage (with droshaQ884X)
lethal | larval stage (with droshaW1123X)
lethal | pupal stage (with droshaQ884X)
lethal | pupal stage (with droshaW1123X)
lethal | recessive
lethal - all die before end of P-stage (with Df(2R)Exel6055)
partially lethal, with Scer\GAL4tin.CΔ4
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
Other Phenotypes
Allele
majority die during larval stage (with Df(2R)Exel6055)
majority die during prepupal stage (with Df(2R)Exel6055)
neuroanatomy defective
neuroanatomy defective, with Scer\GAL4ey-OK107
neuroanatomy defective | larval stage
neurophysiology defective | adult stage | somatic clone
some die during pharate adult stage (with Df(2R)Exel6055)
visible, with Scer\GAL4nub-AC-62
visible, with Scer\GAL4pnr-MD237
visible | somatic clone
Phenotype manifest in
Allele
adult antennal lobe projection neuron adPN | somatic clone
adult antennal lobe projection neuron DL1 adPN | somatic clone
alpha/beta Kenyon cell | somatic clone
alpha'/beta' Kenyon cell, with Scer\GAL4ey-OK107
alpha'/beta' Kenyon cell | somatic clone
embryonic/larval central nervous system (with Df(2R)Exel6055)
eye | somatic clone
eye disc | third instar larval stage
gamma Kenyon cell | somatic clone
imaginal disc (with Df(2R)Exel6055)
imaginal disc | third instar larval stage
larval neuroblast | larval stage
mesothoracic tergum, with Scer\GAL4pnr-MD237
mushroom body | somatic clone
mushroom body gamma-lobe
oocyte | germline clone
salivary gland | pupal stage, with Scer\GAL4fkh.PU
trichogen cell, with Scer\GAL4pnr-MD237
wing, with Scer\GAL4nub-AC-62
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\DROSHA
13 of 15
Yes
Yes
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Drosha
13 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (1)
Rnor\Drosha
12 of 13
Yes
Yes
Xenopus tropicalis (Western clawed frog) (1)
Xtro\drosha
5 of 12
Yes
Yes
Danio rerio (Zebrafish) (1)
Drer\rnasen
9 of 15
Yes
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\drsh-1
14 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (5)
Atha\AT4G37510
1 of 9
Yes
Yes
Atha\DCL2
1 of 9
Yes
No
Atha\HYL1
1 of 9
Yes
Yes
Atha\NFD2
1 of 9
Yes
Yes
Atha\RTL1
1 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\RNT1
5 of 15
Yes
Yes
Scer\MRPL3
1 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\pac1
4 of 12
Yes
Yes
Spom\mrpl3
1 of 12
No
No
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091900SI )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\drosha
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00006679
Drosophila simulans
Dsim\GD10519
Drosophila sechellia
Dsec\GM20991
Drosophila erecta
Dere\GG23313
Drosophila yakuba
Dyak\GE19158
Drosophila ananassae
Dana\GF13644
Drosophila pseudoobscura pseudoobscura
Dpse\GA21287
Drosophila persimilis
Dper\GL11697
Drosophila willistoni
Dwil\GK23200
Drosophila virilis
Dvir\GJ15113
Drosophila mojavensis
Dmoj\GI19789
Drosophila grimshawi
Dgri\GH21300
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500ZL )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17012363
Glossina morsitans
Tsetse fly
Gmor\GMOY008669
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_10219
Mayetiola destructor
Hessian fly
Mdes\Mdes002849
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL008592
Anopheles darlingi
American malaria mosquito
Adar\ADAC002334
Anopheles gambiae
Malaria mosquito
Agam\AGAP008087
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ001734
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0103 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Danaus plexippus
Monarch butterfly
Dple\DPOGS206644-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL011141
Apis florea
Little honeybee
Aflo\3251671876
Apis mellifera
Western honey bee
Amel\Ame.16452
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP25827
Bombus terrestris
Buff-tailed bumblebee
Bter\15215425
Linepithema humile
Argentine ant
Lhum\LH13451
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:000363
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG019932
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04998
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04999
Tribolium castaneum
Red flour beetle
Tcas\TC031425
Pediculus humanus
Human body louse
Phum\PHUM524860
Rhodnius prolixus
Kissing bug
Rpro\RPRC013112
Cimex lectularius
Bed bug
Clec\CLEC025177
Cimex lectularius
Bed bug
Clec\CLEC011511
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001907
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_12973
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X00YB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR002320
Ixodes scapularis
Black-legged tick
Isca\ISCW023600
Stegodyphus mimosarum
African social velvet spider
Smim\KFM76178.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur12g00910
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_442
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02A9 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Rnase3l_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Rnase3l
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000001525
Gallus gallus
Domestic chicken
Ggal\RNASEN
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (1)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
mRpL44
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    DROSHA; drosha ribonuclease III
    13 of 15
    608828
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Show neighbor-neighbor interactions:
        Select Layout:
        Legend:
        Protein
        RNA
        Selected Interactor(s)
        Interactions Browser
        View in Interactions Browser
        Please see the Physical Interaction reports below for full details
        RNA-protein
        Physical Interaction
        Assay
        References
        drosha - mir-ban
        enzymatic study, northern blot
        (Denli et al., 2004)
        protein-protein
        Physical Interaction
        Assay
        References
        drosha
        anti tag coimmunoprecipitation, anti tag western blot
        (Luhur et al., 2014)
        drosha - pasha
        anti tag coimmunoprecipitation, western blot, ion exchange chromatography, molecular sieving, anti bait coimmunoprecipitation, anti tag western blot
        (Mugat et al., 2015, Xiong et al., 2015, Luhur et al., 2014, Denli et al., 2004)
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        w
        suppressible
        drosha
        (Smibert et al., 2011)
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Gene Group - Pathway Membership (FlyBase)
        External Data
        Linkouts
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2R
        Recombination map
        2-57
        Cytogenetic map
        43F2-43F3
        Sequence location
        2R:7,932,429..7,936,840 [+]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        43F2-43F3
        Limits computationally determined from genome sequence between P{lacW}lin19k01207&P{lacW}rnh1k07624 and P{lacW}CSN4k08018&P{lacW}l(2)k08504k08504
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        Experimentally Determined Recombination Data
        Location
        2-57
        (FlyBase, 2016)
        2-57.2
        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (5)
        Genomic Clones (12)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (54)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequences
        BDGP DGC clones
        Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           
          monoclonal
          (Na et al., 2016)
          polyclonal
          (Denli et al., 2004)
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of
          Source for database merge of
          Additional comments
          Other Comments
          drosha is required for the production of later born α/β and α/β neurons and suggests that drosha processing of RNAs in addition to let-7 and mir-125 promotes neuroblast maintenance.
          (Luhur et al., 2014)
          RNAi knockdown of drosha function in S2 cells results in an accumulation of pri-miRNAs and a reduction of pre-miRNAs and mature miRNAs.
          (Landthaler et al., 2004)
          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 36 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          modMine - A data warehouse for the modENCODE project
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyMine - An integrated database for Drosophila genomics
          Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Synonyms and Secondary IDs (4)
          Reported As
          Symbol Synonym
          CG8730
          (Na et al., 2016, Hosono et al., 2015, Ding et al., 2014, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009)
          DROSHA
          (Kolaczkowski et al., 2011)
          Drosha
          (Liu et al., 2019, Swevers et al., 2018, Yamashiro and Siomi, 2018, Azlan et al., 2016, Brewer-Jensen et al., 2016, Truscott et al., 2016, Yang et al., 2016, Chak et al., 2015, Mugat et al., 2015, Xiong et al., 2015, Barrio et al., 2014, Chawla and Sokol, 2014, Luhur et al., 2014, Carré et al., 2013, Hu et al., 2013, Meister, 2013, Okamura et al., 2013, Sabin et al., 2013, Xiong et al., 2013, Pressman et al., 2012, Pushpavalli et al., 2012, Westholm et al., 2012, Liu et al., 2011, Ni et al., 2011, Qian et al., 2011, Flynt et al., 2010, Swami, 2010, Hartig et al., 2009, Hu et al., 2009, Hwang et al., 2009, Okamura et al., 2009, Zhou et al., 2009, Chung et al., 2008, Kawamura et al., 2008, Okamura et al., 2008, Okamura et al., 2008, Zhou et al., 2008, Eulalio et al., 2007, Okamura et al., 2007, Yu et al., 2007, Dorner et al., 2006, Valencia-Sanchez et al., 2006, Pearson et al., 2005, Denli et al., 2004)
          drosha
          (Liu et al., 2019, Mohorianu et al., 2018, Gerstberger et al., 2017, Funikov et al., 2016, Na et al., 2016, Sanfilippo et al., 2016, Faisal et al., 2014, Nelson et al., 2014, Smibert et al., 2013, Azzam et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Lindquist et al., 2011, Smibert et al., 2011, Czech et al., 2009, Förstemann et al., 2007, Ruby et al., 2007, Ruby et al., 2007, Han et al., 2006)
          Name Synonyms
          Drosha
          (Xiong et al., 2016, Besnard-Guérin et al., 2015, Lucas et al., 2015, Sabin et al., 2009, Czech et al., 2008, Jacquier et al., 2008, Eulalio et al., 2007, Yu et al., 2007, Rehwinkel et al., 2006, Denli et al., 2004, Schmittgen et al., 2004)
          drosha
          (Faisal et al., 2014, Kadener et al., 2009, Kadener et al., 2009)
          Secondary FlyBase IDs
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            References (133)