Gene Dmel\Trap1

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General Information

Symbol

Dmel\Trap1

Species

D. melanogaster

Name

Trap1

Annotation symbol

CG3152

Feature type

protein_coding_gene

FlyBase ID

FBgn0026761

Gene Model Status

Current

Stock availability

5 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

42B2-42B2

Sequence location

2R:2,521,152..2,523,767 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene Trap1 is referred to in FlyBase by the symbol Dmel\Trap1 (CG3152, FBgn0026761). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATPase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: protein folding; response to stress. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Heat shock protein Hsp90; Heat shock protein Hsp90, N-terminal; Histidine kinase-like ATPase, ATP-binding domain; Ribosomal protein S5 domain 2-type fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634173_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Trap1. Gene sequence location is 2R:2521152..2523767.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

Alleles

Trap1[Scer\UAS.cCa]

Trap1[4]

Transgenic Constructs

P{UAS-Trap1.C}

Controlled Vocabulary Terms

response to oxidative stress

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

42B2-42B2

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\Trap1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Gene model reviewed during 5.41

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Trap1-RA

FBtr0086149

NM_058091

2478

691

Trap1-RB

FBtr0336666

NM_001273797

2303

691

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Trap1-PA

FBpp0085482

78.0

691

7.68

NP_477439

AAF57362

Trap1-PB

FBpp0307647

78.0

691

7.68

NP_001260726

AGB93259

Additional Polypeptide Data & Comments

Reported size (kDa)

686 (aa)

(Felts et al., 2000)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Heat shock protein Hsp90 (IPR001404)

Histidine kinase-like ATPase, ATP-binding domain (IPR003594)

Ribosomal protein S5 domain 2-type fold (IPR020568)

Heat shock protein Hsp90, N-terminal (IPR020575)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 2

organism | ubiquitous & uniform

(Pflanz and Hoch, 2000)

Comment:maternally supplied

embryonic stage 3 -- 4

organism | 0-10% egg length

(Pflanz and Hoch, 2000)

Comment:localized to posterior pole

embryonic stage 7 -- 10

mesoderm

(Pflanz and Hoch, 2000)

Comment:zygotic expression

endoderm

(Pflanz and Hoch, 2000)

Comment:zygotic expression

embryonic stage 11 -- 13

fat body/gonad primordium

(Pflanz and Hoch, 2000)

embryonic stage 11 -- 14

embryonic/larval midgut primordium

(Pflanz and Hoch, 2000)

embryonic hindgut

(Pflanz and Hoch, 2000)

embryonic somatic muscle

(Pflanz and Hoch, 2000)

dorsal pharyngeal muscle primordium

(Pflanz and Hoch, 2000)

embryonic stage 14

fat body primordium

(Pflanz and Hoch, 2000)

embryonic stage 15

embryonic/larval somatic muscle

(Pflanz and Hoch, 2000)

embryonic stage 15 -- 17

embryonic/larval midgut | restricted

(Pflanz and Hoch, 2000)

Comment:3 expression domains

pharyngeal muscle

(Pflanz and Hoch, 2000)

lateral longitudinal muscle 1

• nucleus | vicinity of

(Pflanz and Hoch, 2000)

oogenesis stage S4 -- S14

oocyte

• cytoplasm

(Pflanz and Hoch, 2000)

Additional Descriptive Data

Expression in developing somatic muscles is ephemeral

(Pflanz and Hoch, 2000)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

lipid particle

inferred from direct assay

(Beller et al., 2006)

mitochondrion

inferred from direct assay

(Costa et al., 2013)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		163.55
Larval Midgut		123.5
Larval Hindgut		265.8
Larval Malpighian Tubules		95.6
Larval Fat Body		113.7
Larval Salivary Gland		197.5
Larval Trachea		200.975
Larval Carcass		167.725
Adult Head		142.4
Adult Eye		170.925
Adult Brain		237.8
Adult Thoracic-Abdominal Ganglion		408.6
Adult Crop		125.3
Adult Midgut		108.1
Adult Hindgut		163.4
Adult Malpighian Tubules		238.2
Adult Fat Body		160.6
Adult Salivary Gland		194.2
Adult Heart		192.75
Adult VirginFemale Spermatheca		179.7
Adult InseminatedFemale Spermatheca		190.2
Adult Ovary		201.6
Adult Testis		486.8
Adult Male Accessory Gland		120.9
Adult Carcass		177.8
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	142.4
NA	Eye	170.925
NA	Brain	237.8
163.55	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	408.6
NA	Crop	125.3
123.5	Midgut	108.1
265.8	Hindgut	163.4
95.6	Malpighian Tubules	238.2
113.7	Fat Body	160.6
197.5	Salivary Gland	no informative data
NA	Heart	192.75
200.975	Trachea	NA
NA	VirginFemale Spermatheca	179.7
NA	InseminatedFemale Spermatheca	190.2
NA	Ovary	201.6
NA	Testis	486.8
NA	Male Accessory Gland	120.9
167.725	Carcass	177.8

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		57
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		110
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(57)
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		(29)
ovary, mated 4-day female		22
testis, mated 4-day male		(110)
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		57
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		(110)
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		57
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		110
accessory gland, mated 4-day male		15
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		57
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		110
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(57)
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		(110)
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		57
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		110
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		57
central nervous system, larvae L3		13
central nervous system, pupae P8		14
head, virgin 1-day female		15
head, virgin 4-day female		12
head, virgin 20-day female		16
head, mated 1-day female		13
head, mated 4-day female		13
head, mated 20-day female		12
head, mated 1-day male		19
head, mated 4-day male		19
head, mated 20-day male		24
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		3
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		10
digestive system, 4-day adult		12
digestive system, 20-day adult		10
fat body, larvae L3 wandering		4
fat body, white prepupae		13
fat body, pupae P8		24
carcass, larvae L3 wandering		13
carcass, 1-day adult		11
carcass, 4-day adult		15
carcass, 20-day adult		17
ovary, virgin 4-day female		29
ovary, mated 4-day female		22
testis, mated 4-day male		110
accessory gland, mated 4-day male		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		45
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		36
embryo 08-10hr		45
embryo 10-12hr		67
embryo 12-14hr		58
embryo 14-16hr		58
embryo 16-18hr		53
embryo 18-20hr		43
embryo 20-22hr		42
embryo 22-24hr		40
larva L1		76
larva L2		71
larva L3 12hr old		51
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		34
pupae 2d postWPP		54
pupae 3d postWPP		39
pupae 4d postWPP		30
adult male 01day		47
adult male 05day		59
adult male 30day		56
adult female 01day		36
adult female 05day		41
adult female 30day		41
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(45)
embryo 02-04hr		15
embryo 04-06hr		(27)
embryo 06-08hr		(36)
embryo 08-10hr		(45)
embryo 10-12hr		(67)
embryo 12-14hr		(58)
embryo 14-16hr		(58)
embryo 16-18hr		(53)
embryo 18-20hr		(43)
embryo 20-22hr		(42)
embryo 22-24hr		(40)
larva L1		(76)
larva L2		(71)
larva L3 12hr old		(51)
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		(34)
pupae 2d postWPP		(54)
pupae 3d postWPP		(39)
pupae 4d postWPP		(30)
adult male 01day		(47)
adult male 05day		(59)
adult male 30day		(56)
adult female 01day		(36)
adult female 05day		(41)
adult female 30day		(41)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		45
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		36
embryo 08-10hr		45
embryo 10-12hr		67
embryo 12-14hr		58
embryo 14-16hr		58
embryo 16-18hr		53
embryo 18-20hr		43
embryo 20-22hr		42
embryo 22-24hr		40
larva L1		76
larva L2		71
larva L3 12hr old		51
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		34
pupae 2d postWPP		54
pupae 3d postWPP		39
pupae 4d postWPP		30
adult male 01day		47
adult male 05day		59
adult male 30day		56
adult female 01day		36
adult female 05day		41
adult female 30day		41
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		45
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		36
embryo 08-10hr		45
embryo 10-12hr		67
embryo 12-14hr		58
embryo 14-16hr		58
embryo 16-18hr		53
embryo 18-20hr		43
embryo 20-22hr		42
embryo 22-24hr		40
larva L1		76
larva L2		71
larva L3 12hr old		51
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		34
pupae 2d postWPP		54
pupae 3d postWPP		39
pupae 4d postWPP		30
adult male 01day		47
adult male 05day		59
adult male 30day		56
adult female 01day		36
adult female 05day		41
adult female 30day		41
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		45
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		36
embryo 08-10hr		45
embryo 10-12hr		67
embryo 12-14hr		58
embryo 14-16hr		58
embryo 16-18hr		53
embryo 18-20hr		43
embryo 20-22hr		42
embryo 22-24hr		40
larva L1		76
larva L2		71
larva L3 12hr old		51
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		34
pupae 2d postWPP		54
pupae 3d postWPP		39
pupae 4d postWPP		30
adult male 01day		47
adult male 05day		59
adult male 30day		56
adult female 01day		36
adult female 05day		41
adult female 30day		41
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(45)
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		(36)
embryo 08-10hr		(45)
embryo 10-12hr		(67)
embryo 12-14hr		(58)
embryo 14-16hr		(58)
embryo 16-18hr		(53)
embryo 18-20hr		(43)
embryo 20-22hr		(42)
embryo 22-24hr		(40)
larva L1		(76)
larva L2		(71)
larva L3 12hr old		(51)
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		(34)
pupae 2d postWPP		(54)
pupae 3d postWPP		(39)
pupae 4d postWPP		30
adult male 01day		(47)
adult male 05day		(59)
adult male 30day		(56)
adult female 01day		(36)
adult female 05day		(41)
adult female 30day		(41)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		45
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		36
embryo 08-10hr		45
embryo 10-12hr		67
embryo 12-14hr		58
embryo 14-16hr		58
embryo 16-18hr		53
embryo 18-20hr		43
embryo 20-22hr		42
embryo 22-24hr		40
larva L1		76
larva L2		71
larva L3 12hr old		51
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		34
pupae 2d postWPP		54
pupae 3d postWPP		39
pupae 4d postWPP		30
adult male 01day		47
adult male 05day		59
adult male 30day		56
adult female 01day		36
adult female 05day		41
adult female 30day		41
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		45
embryo 02-04hr		15
embryo 04-06hr		27
embryo 06-08hr		36
embryo 08-10hr		45
embryo 10-12hr		67
embryo 12-14hr		58
embryo 14-16hr		58
embryo 16-18hr		53
embryo 18-20hr		43
embryo 20-22hr		42
embryo 22-24hr		40
larva L1		76
larva L2		71
larva L3 12hr old		51
larva L3 puffstage 1-2		16
larva L3 puffstage 3-6		20
larva L3 puffstage 7-9		20
white prepupae new		20
white prepupae 12hr		25
white prepupae 24hr		34
pupae 2d postWPP		54
pupae 3d postWPP		39
pupae 4d postWPP		30
adult male 01day		47
adult male 05day		59
adult male 30day		56
adult female 01day		36
adult female 05day		41
adult female 30day		41
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		49
Schneider line 2 Sg4		29
embryonic 1182-4H		36
embryonic GM2		36
embryonic Kc167		32
embryonic S1		58
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		38
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		38
wing disc ML-DmD32		40
haltere disc ML-DmD17-c3		40
eye-antennal disc ML-DmD11		77
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		35
CNS ML-DmBG1-c1		49
CNS ML-DmBG2-c2		67
tumorous blood cells mbn2		34
ovary fGS/OSS		30
ovary OSC		54
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(49)
Schneider line 2 Sg4		(29)
embryonic 1182-4H		(36)
embryonic GM2		(36)
embryonic Kc167		(32)
embryonic S1		(58)
embryonic S3		(31)
leg disc CME L1		(27)
wing disc CME-W2		(28)
wing disc ML-DmD8		(27)
wing disc ML-DmD9		(38)
wing disc ML-DmD16-c3		(30)
wing disc ML-DmD21		(38)
wing disc ML-DmD32		(40)
haltere disc ML-DmD17-c3		(40)
eye-antennal disc ML-DmD11		(77)
antennal disc ML-DmD20-c5		(27)
mixed discs ML-DmD4-c1		(35)
CNS ML-DmBG1-c1		(49)
CNS ML-DmBG2-c2		(67)
tumorous blood cells mbn2		(34)
ovary fGS/OSS		(30)
ovary OSC		(54)
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		49
Schneider line 2 Sg4		29
embryonic 1182-4H		36
embryonic GM2		36
embryonic Kc167		32
embryonic S1		58
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		38
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		38
wing disc ML-DmD32		40
haltere disc ML-DmD17-c3		40
eye-antennal disc ML-DmD11		77
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		35
CNS ML-DmBG1-c1		49
CNS ML-DmBG2-c2		67
tumorous blood cells mbn2		34
ovary fGS/OSS		30
ovary OSC		54
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		49
Schneider line 2 Sg4		29
embryonic 1182-4H		36
embryonic GM2		36
embryonic Kc167		32
embryonic S1		58
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		38
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		38
wing disc ML-DmD32		40
haltere disc ML-DmD17-c3		40
eye-antennal disc ML-DmD11		77
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		35
CNS ML-DmBG1-c1		49
CNS ML-DmBG2-c2		67
tumorous blood cells mbn2		34
ovary fGS/OSS		30
ovary OSC		54
ovary OSS		13
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		49
Schneider line 2 Sg4		29
embryonic 1182-4H		36
embryonic GM2		36
embryonic Kc167		32
embryonic S1		58
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		38
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		38
wing disc ML-DmD32		40
haltere disc ML-DmD17-c3		40
eye-antennal disc ML-DmD11		77
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		35
CNS ML-DmBG1-c1		49
CNS ML-DmBG2-c2		67
tumorous blood cells mbn2		34
ovary fGS/OSS		30
ovary OSC		54
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(49)
Schneider line 2 Sg4		29
embryonic 1182-4H		(36)
embryonic GM2		(36)
embryonic Kc167		32
embryonic S1		(58)
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		(38)
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		(38)
wing disc ML-DmD32		(40)
haltere disc ML-DmD17-c3		(40)
eye-antennal disc ML-DmD11		(77)
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		(35)
CNS ML-DmBG1-c1		(49)
CNS ML-DmBG2-c2		(67)
tumorous blood cells mbn2		(34)
ovary fGS/OSS		30
ovary OSC		(54)
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		49
Schneider line 2 Sg4		29
embryonic 1182-4H		36
embryonic GM2		36
embryonic Kc167		32
embryonic S1		58
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		38
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		38
wing disc ML-DmD32		40
haltere disc ML-DmD17-c3		40
eye-antennal disc ML-DmD11		77
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		35
CNS ML-DmBG1-c1		49
CNS ML-DmBG2-c2		67
tumorous blood cells mbn2		34
ovary fGS/OSS		30
ovary OSC		54
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		49
Schneider line 2 Sg4		29
embryonic 1182-4H		36
embryonic GM2		36
embryonic Kc167		32
embryonic S1		58
embryonic S3		31
leg disc CME L1		27
wing disc CME-W2		28
wing disc ML-DmD8		27
wing disc ML-DmD9		38
wing disc ML-DmD16-c3		30
wing disc ML-DmD21		38
wing disc ML-DmD32		40
haltere disc ML-DmD17-c3		40
eye-antennal disc ML-DmD11		77
antennal disc ML-DmD20-c5		27
mixed discs ML-DmD4-c1		35
CNS ML-DmBG1-c1		49
CNS ML-DmBG2-c2		67
tumorous blood cells mbn2		34
ovary fGS/OSS		30
ovary OSC		54
ovary OSS		13
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		10
heat shock, 4-day adult		16
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		19
Cadmium 100 mM 48 hrs, 4-day adult		20
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		12
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		14
Ethanol 2.5% 3 hrs, larvae L3		24
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		13
Caffeine 1.5 mg/ml 4 hrs, larvae L3		11
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		21
Caffeine 25 mg/ml 48 hrs, 4-day adult		10
Paraquat 5 mM 48 hrs, 4-day adult		26
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		15
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010)

mE2_34_mRNA_expression_cluster_19

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0026761

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG3152-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

Sterility

Allele

fertile

Trap1^EY10238

Other Phenotypes

Allele

chemical resistant, with Scer\GAL4^da.G32

Trap1^Scer\UAS.cCa

chemical sensitive

Trap1⁴

heat stress response defective

Trap1⁴

locomotor behavior defective | adult stage | progressive

Trap1⁴

locomotor behavior defective | adult stage | progressive, with Scer\GAL4^da.G32

Trap1^Scer\UAS.cCa

oxidative stress response defective

Trap1⁴

oxidative stress response defective, with Scer\GAL4^da.G32

Trap1^Scer\UAS.cCa

short lived

Trap1⁴

Phenotype manifest in

Allele

Classical Alleles ( 8 )

For All Classical Alleles Show

Allele of Trap1	Class	Mutagen	Stocks	Known lesion
Trap1^c03329		piggyBac transposase	1	--
Trap1^EY10238		P-element activity	1	--
Trap1^EY21851		P-element activity	1	--
Trap1^KG06242		P-element activity	1	--
Trap1⁴	amorphic allele - molecular evidence	P-element activity	0	Yes
Trap1^EP2052		P-element activity	0	--
Trap1^Δ115		Delta2-3	0	Yes
Trap1^Δ135		Delta2-3	0	Yes

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Trap1	Mutagen	Stocks	Known lesion
Trap1^KK102212	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Trap1^GD10279	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
Trap1^NIG.3152R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
Trap1^Scer\UAS.cCa	in vitro construct - regulatory fusion	0	Yes