• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\MED18

General Information
Symbol	Dmel\MED18	Species	D. melanogaster
Name	Mediator complex subunit 18	Annotation symbol	CG14802
Feature type	protein_coding_gene	FlyBase ID	FBgn0026873
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	p28/CG14802, dp28b, EG:63B12.13
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	2B13-2B13	Sequence location	X:1,759,942..1,760,920 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Mediator complex subunit 18 is referred to in FlyBase by the symbol Dmel\MED18 (CG14802, FBgn0026873). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA polymerase II transcription cofactor activity. There is experimental evidence that it is involved in the biological process: transcription from RNA polymerase II promoter. 8 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Mediator complex, subunit Med18, metazoa/fungi. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638834_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of MED18. Gene sequence location is X:1759942..1760920.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 2B13-2B13   Limits computationally determined from genome sequence between P{EP}brEP1515 and P{EP}EP1444&P{EP}CG14818EP1190
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\MED18 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) MED18-RA FBtr0070308  NM_130592   842   217 MED18-RC FBtr0114454  NM_001144673   865   50
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein MED18-PA   FBpp0070295   24.7   217   7.88     NP_569948   AAF45675 MED18-PC   FBpp0112946   5.5   50   5.39     NP_001138145   ACL82878
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Mediator complex, subunit Med18, metazoa/fungi (IPR019095)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF45675   AE014298 ACL82878   AI389118   AL021106 CAB41707   AY119167 AAM51027   BG633101   BI588512   BI632440   BT071807   CO178795   CO181687   CO268849   CO269031   CO303286   CO342267   CZ481604   EC071131   EC195861   EC203128   EC219989   EC252268   EC260725
UniProtKB/Swiss-Prot	Q9XZT1
UniProtKB/TrEMBL	B7Z116
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
mediator complex inferred from direct assay (Gu et al., 2002) inferred from direct assay (assigned by UniProtKB) (Park et al., 2001) nucleus inferred from direct assay (Gu et al., 2002)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    272.9 Larval Midgut    69.5 Larval Hindgut    86.5 Larval Malpighian Tubules    122.3 Larval Fat Body    168.1 Larval Salivary Gland    229.5 Larval Trachea    139.575 Larval Carcass    137.75 Adult Head    125.9 Adult Eye    150.3 Adult Brain    140 Adult Thoracic-Abdominal Ganglion    152.2 Adult Crop    191.4 Adult Midgut    97.3 Adult Hindgut    85.8 Adult Malpighian Tubules    91.3 Adult Fat Body    119.4 Adult Salivary Gland    126.4 Adult Heart    124.775 Adult VirginFemale Spermatheca    243.6 Adult InseminatedFemale Spermatheca    278.3 Adult Ovary    334.8 Adult Testis    120.6 Adult Male Accessory Gland    226 Adult Carcass    128.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    125.9   NA  Eye    150.3   NA  Brain    140   272.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    152.2   NA  Crop    191.4   69.5  Midgut    97.3   86.5  Hindgut    85.8   122.3  Malpighian Tubules    91.3   168.1  Fat Body    119.4   229.5  Salivary Gland    126.4   NA  Heart    124.775   139.575  Trachea    NA   NA  VirginFemale Spermatheca    243.6   NA  InseminatedFemale Spermatheca    278.3   NA  Ovary    334.8   NA  Testis    120.6   NA  Male Accessory Gland    226   137.75  Carcass    128.3 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female    29 testis, mated 4-day male    27 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female  (29) testis, mated 4-day male  (27) accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female    29 testis, mated 4-day male    27 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female    29 testis, mated 4-day male    27 accessory gland, mated 4-day male    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female    29 testis, mated 4-day male    27 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female  29 testis, mated 4-day male  27 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female    29 testis, mated 4-day male    27 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    25 central nervous system, larvae L3    20 central nervous system, pupae P8    14 head, virgin 1-day female    8 head, virgin 4-day female    8 head, virgin 20-day female    6 head, mated 1-day female    5 head, mated 4-day female    6 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    8 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    7 fat body, pupae P8    17 carcass, larvae L3 wandering    17 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    4 ovary, virgin 4-day female    25 ovary, mated 4-day female    29 testis, mated 4-day male    27 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    44 embryo 02-04hr    31 embryo 04-06hr    47 embryo 06-08hr    55 embryo 08-10hr    47 embryo 10-12hr    46 embryo 12-14hr    26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day    31 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (44) embryo 02-04hr  (31) embryo 04-06hr  (47) embryo 06-08hr  (55) embryo 08-10hr  (47) embryo 10-12hr  (46) embryo 12-14hr  26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr  (29) pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day  (31) adult female 30day  (32) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    44 embryo 02-04hr    31 embryo 04-06hr    47 embryo 06-08hr    55 embryo 08-10hr    47 embryo 10-12hr    46 embryo 12-14hr    26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day    31 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    44 embryo 02-04hr    31 embryo 04-06hr    47 embryo 06-08hr    55 embryo 08-10hr    47 embryo 10-12hr    46 embryo 12-14hr    26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day    31 adult female 30day    32 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    44 embryo 02-04hr    31 embryo 04-06hr    47 embryo 06-08hr    55 embryo 08-10hr    47 embryo 10-12hr    46 embryo 12-14hr    26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day    31 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (44) embryo 02-04hr  31 embryo 04-06hr  (47) embryo 06-08hr  (55) embryo 08-10hr  (47) embryo 10-12hr  (46) embryo 12-14hr  26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr  29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day  31 adult female 30day  32 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    44 embryo 02-04hr    31 embryo 04-06hr    47 embryo 06-08hr    55 embryo 08-10hr    47 embryo 10-12hr    46 embryo 12-14hr    26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day    31 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    44 embryo 02-04hr    31 embryo 04-06hr    47 embryo 06-08hr    55 embryo 08-10hr    47 embryo 10-12hr    46 embryo 12-14hr    26 embryo 14-16hr    19 embryo 16-18hr    15 embryo 18-20hr    14 embryo 20-22hr    12 embryo 22-24hr    10 larva L1    14 larva L2    16 larva L3 12hr old    13 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    22 white prepupae new    20 white prepupae 12hr    21 white prepupae 24hr    29 pupae 2d postWPP    25 pupae 3d postWPP    17 pupae 4d postWPP    11 adult male 01day    14 adult male 05day    17 adult male 30day    15 adult female 01day    20 adult female 05day    31 adult female 30day    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    29 Schneider line 2 Sg4    35 embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1    28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    41 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    28 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (29) Schneider line 2 Sg4  (35) embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1  (28) embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3  (36) wing disc ML-DmD21  (41) wing disc ML-DmD32  (35) haltere disc ML-DmD17-c3  (41) eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5  (28) mixed discs ML-DmD4-c1  (34) CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    29 Schneider line 2 Sg4    35 embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1    28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    41 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    28 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    29 Schneider line 2 Sg4    35 embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1    28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    41 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    28 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    29 Schneider line 2 Sg4    35 embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1    28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    41 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    28 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  29 Schneider line 2 Sg4  (35) embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1  28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3  (36) wing disc ML-DmD21  (41) wing disc ML-DmD32  (35) haltere disc ML-DmD17-c3  (41) eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5  28 mixed discs ML-DmD4-c1  (34) CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    29 Schneider line 2 Sg4    35 embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1    28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    41 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    28 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    29 Schneider line 2 Sg4    35 embryonic 1182-4H    19 embryonic GM2    11 embryonic Kc167    21 embryonic S1    28 embryonic S3    10 leg disc CME L1    22 wing disc CME-W2    15 wing disc ML-DmD8    25 wing disc ML-DmD9    25 wing disc ML-DmD16-c3    36 wing disc ML-DmD21    41 wing disc ML-DmD32    35 haltere disc ML-DmD17-c3    41 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    28 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    24 tumorous blood cells mbn2    15 ovary fGS/OSS    23 ovary OSC    23 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    7 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    25 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    12 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    14 Rotenone 8 μg 12 hrs, larvae L3    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026873 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14802-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 MED18GD12434 MED18GD16153 Other Phenotypes Allele cell growth defective MED18a.cKa MED18cKa visible, with Scer\GAL4pnr-MD237 MED18GD12434 MED18GD16153 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 MED18GD16153 trichogen cell, with Scer\GAL4pnr-MD237 MED18GD12434 MED18GD16153
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of MED18 Class Mutagen Stocks Known lesion MED18e03853 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of MED18 Class Mutagen Stocks Known lesion MED18GD12434 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes MED18GD16153 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes MED18HMS02470 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes MED18KK108157 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes MED18a.cKa in vitro construct - RNAi 0 Yes MED18cKa in vitro construct - RNAi 0 Yes MED18NIG.14802R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12434} NA P{GD16153} NA P{KK108157} NA P{NIG.14802R} NA P{TRiP.HMS02470} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}MED18e03853 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
RNA polymerase II transcription cofactor activity inferred from mutant phenotype (assigned by UniProtKB) (Park et al., 2001)
Biological Process
CV term Evidence References
transcription from RNA polymerase II promoter inferred from mutant phenotype (assigned by UniProtKB) (Park et al., 2001)
Cellular Component
CV term Evidence References
mediator complex inferred from direct assay (Gu et al., 2002) inferred from direct assay (assigned by UniProtKB) (Park et al., 2001) nucleus inferred from direct assay (Gu et al., 2002)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
contributes_to RNA polymerase II transcription cofactor activity inferred by curator from GO:0016592 (Gu et al., 2002)
Biological Process
CV term Evidence References
regulation of transcription from RNA polymerase II promoter inferred by curator from GO:0016592 (Gu et al., 2002) inferred from electronic annotation with InterPro:IPR019095 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
MED18 - Bap55 experimental knowledge based (Guruharsha et al., 2011) MED18 - Bap60 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG11505 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG12493 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - CG15625 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - CG17002 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG2017 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG3008 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG30491 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - CG32479 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG34159 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG3689 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG5623 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - CG7185 experimental knowledge based (Guruharsha et al., 2011) MED18 - CG7542 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) MED18 - Cdk8 experimental knowledge based (Guruharsha et al., 2011) MED18 - Der-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - MED10 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED11 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED14 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED15 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED16 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED17 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED20 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED23 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED27 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED30 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED31 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED4 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED6 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED7 experimental knowledge based (Guruharsha et al., 2011) MED18 - MED8 experimental knowledge based (Guruharsha et al., 2011) MED18 - Pa1 experimental knowledge based (Guruharsha et al., 2011) MED18 - Psi experimental knowledge based (Guruharsha et al., 2011) MED18 - Rrp45 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - Snr1 experimental knowledge based (Guruharsha et al., 2011) MED18 - Ssdp experimental knowledge based (Guruharsha et al., 2011) MED18 - boca experimental knowledge based (Guruharsha et al., 2011) MED18 - brm experimental knowledge based (Guruharsha et al., 2011) MED18 - dsh experimental knowledge based (Guruharsha et al., 2011) MED18 - ebi experimental knowledge based (Guruharsha et al., 2011) MED18 - enc experimental knowledge based (Guruharsha et al., 2011) MED18 - fan anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - fh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) MED18 - ix experimental knowledge based (Guruharsha et al., 2011) MED18 - mor experimental knowledge based (Guruharsha et al., 2011) MED18 - osa experimental knowledge based (Guruharsha et al., 2011) MED18 - ptip experimental knowledge based (Guruharsha et al., 2011) MED18 - sec24 experimental knowledge based (Guruharsha et al., 2011) MED18 - skd experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions MED18 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57686 DroID - A comprehensive database of gene and protein interactions. • FBgn0026873 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31140
Orthologs
OrthoDB Orthologs (35) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6XSM97 Dipteran inclusive ortholog search EOG6DNFDJ Insect inclusive ortholog search EOG6DJHSK Arthropod inclusive ortholog search EOG63XSKJ Metazoa inclusive ortholog search EOG696BMD
Orthologs in Drosophila Species (EOG6XSM97)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\MED18     Drosophila sechellia   Dsec\GM19171 Y   Drosophila erecta   Dere\GG12884 Y   Drosophila yakuba   Dyak\GE16712 Y   Drosophila ananassae   Dana\GF21201 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13258 Y   Drosophila persimilis   Dper\GL20340 Y   Drosophila willistoni   Dwil\GK10069 Y   Drosophila virilis   Dvir\GJ16392 Y   Drosophila mojavensis   Dmoj\GI11081 Y   Drosophila grimshawi   Dgri\GH24653 Y
Orthologs in non-Drosophila Dipterans (EOG6DNFDJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\MED18   Anopheles gambiae Malaria mosquito  Agam\AGAP010936   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006001
Orthologs in non-Dipteran Insects (EOG6DJHSK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\MED18   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG009864   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13628   Atta cephalotes Leafcutter ant  Acep\ACEP16859   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13152   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13882   Linepithema humile Argentine ant  Lhum\LH18877   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11870   Solenopsis invicta Red fire ant  Sinv\SINV25243   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009832   Bombyx mori Silkmoth  Bmor\BGIBMGA007877   Pediculus humanus Human body louse  Phum\PHUM210840   Tribolium castaneum Red flour beetle  Tcas\TC010359
Orthologs in non-Insect Arthropods (EOG63XSKJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_217150   Ixodes scapularis Deer tick  Isca\ISCW017119
Orthologs in non-Arthropod Metazoa (EOG696BMD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\mdt-18   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009277gn   Danio rerio Zebrafish  Drer\med18   Xenopus tropicalis Western clawed frog  Xtro\med18   Mus musculus House mouse  Mmus\Med18   Homo sapiens Human  Hsap\MED18
Human Orthologs (1)
Gene OMIM HGNC Hsap\MED18
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM19171 Drosophila erecta Dere\GG12884 Drosophila yakuba Dyak\GE16712 Drosophila ananassae Dana\GF21201 Drosophila pseudoobscura pseudoobscura Dpse\GA13258 Drosophila persimilis Dper\GL20340 Drosophila willistoni Dwil\GK10069 Drosophila virilis Dvir\GJ16392 Drosophila mojavensis Dmoj\GI11081 Drosophila grimshawi Dgri\GH24653
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	42634 y1 sc* v1; P{TRiP.HMS02470}attP40
Harvard	- PBac{RB}MED18e03853
VDRC	v106760 P{KK108157}VIE-260B v28264 w1118; P{GD12434}v28264 v28265 w1118; P{GD12434}v28265 v48490 w1118; P{GD16153}v48490 v48491 w1118; P{GD16153}v48491
Genomic Clones ( 1 )
	BACR33I18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH29859 SD20918
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH20211 SD26221
Other clones	120975 214279.54 214413.44 CK01.72D.G10 CK01.121B.H10 CK01.122B.G8 EC14837 EK057559 EK092861 EK093360 EK240758 EP14329
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0026873 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31140
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: MED18 CG14802 (Bourbon et al., 2004)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130592 NM_001144673 RefSeq (Proteins) • NP_569948 NP_001138145 DDBJ / EMBL / GenBank • AAF45675 AAM51027 ACL82878 AI389118 AL021106 AY119167 BG633101 BI588512 CAB41707 CZ481604 Entrez Gene - A searchable database of RefSeq genes. • 31140 UniProtKB/Swiss-Prot • Q9XZT1 UniProtKB/TrEMBL • B7Z116
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Mediator complex, subunit Med18, metazoa/fungi (IPR019095)
Linkouts
	BioGRID - A database of protein and genetic interactions • 57686 DroID - A comprehensive database of gene and protein interactions. • FBgn0026873 DRSC - Results from RNAi screens. • FBgn0026873 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0026873 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14802-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0026873 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31140 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31140 modMine - Data generated by the modENCODE project. • FBgn0026873
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	CG14802 (Straub et al., 2005, Benos, 2000.12.13, Keleman et al., 2009.8.5, Ni et al., 2010.12.1) dp28b (Gu et al., 2002, Gim et al., 2001) EG:63B12.13 (Benos et al., 2001, Giot et al., 2003, ) Med18 (Kim et al., 2004, Kim and Lis, 2005) MED18 (Japanese National Institute of Genetics, 2012.5.21) p28 (Park et al., 2001) p28/CG14802 (Bourbon et al., 2004, Guglielmi et al., 2004) Srb5/Med28b (Boube et al., 2002)
Name Synonym	Mediator complex subunit 18 (Bourbon et al., 2004)
Secondary FlyBase IDs
References ( 28 )
Generate a list of	All references relating to this gene ( 28 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 5 ) Review  ( 2 ) Personal communication to FlyBase  ( 9 ) Letter  ( 1 ) Stock list  ( 1 )
Recent research papers ( 1 )
	Baradaran-Heravi et al., 2012, Hum. Mol. Genet. 21(11): 2572--2587 Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression. [FBrf0218299] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...