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Gene Dmel\Inx2

General Information
Symbol	Dmel\Inx2	Species	D. melanogaster
Name	Innexin 2	Annotation symbol	CG4590
Feature type	protein_coding_gene	FlyBase ID	FBgn0027108
Gene Model Status	Current	Stock availability	20 publicly available
Also Known As	Inx2, inx-2, prp33, kropf, Dm-inx2, Ix2, l(1)G0035, l(1)G0043, l(1)G0118
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	6E4-6E4	Sequence location	X:6,892,705..6,898,184 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Innexin 2 is referred to in FlyBase by the symbol Dmel\Inx2 (CG4590, FBgn0027108). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: gap junction channel activity. There is experimental evidence that it is involved in the biological process: intercellular transport; morphogenesis of embryonic epithelium; olfactory behavior; foregut morphogenesis; germarium-derived female germ-line cyst formation; germarium-derived egg chamber formation; cell communication. 44 alleles are reported. The phenotypes of these alleles are annotated with: multicellular structure; organ system; anatomical structure; non-connected developing system; embryonic foregut; embryonic hindgut; portion of tissue; eo support cell; organism subdivision; proventriculus primordium. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Innexin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval midgut, adult fat body, larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval salivary gland, adult female reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640798_a_at completely aligns to an exonic region of only a subset of 2 of the 3 FlyBase-annotated transcript isoforms of inx2. Gene sequence location is X:6892705..6898184.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 6E4-6E4   Limits computationally determined from genome sequence between P{EP}inx7EP1641 and P{EP}CG9650EP1340&P{EP}CG9650EP1617
Experimentally Determined Cytological Location
Cytogenetic map Notes References 6F1-6F2   (determined by in situ hybridisation) 6F1--4 (determined by in situ hybridisation) 6F5--6 (determined by in situ hybridisation) 6E1--2 (determined by in situ hybridisation) 6F1--8 (determined by in situ hybridisation)   (Peter et al., 2002) 6E4-6E5     (Stebbings, 1999.7.25) 6E4-6E5   (determined by in situ hybridisation)   (Stebbings et al., 2000) 6F1-6F8   (determined by in situ hybridisation)   (Schaefer et al., 1999.12.14) 6E4-6E5     (Curtin, 1999.3.25) 6F1-6F2   (determined by in situ hybridisation)   (Schaefer et al., 1999.8.12) 6E4-6E5   (determined by in situ hybridisation)   (Curtin et al., 1999) 6E1-6E5   (determined by in situ hybridisation) 6F1--4 (determined by in situ hybridisation) 6F (determined by in situ hybridisation) 6E4--5 (determined by in situ hybridisation) 6F1--2 (determined by in situ hybridisation)   (Schaefer et al., 1999.6.15) 6E1-6E2   (determined by in situ hybridisation) 6E4--5 (determined by in situ hybridisation) 6F1--2 (determined by in situ hybridisation)   (Schaefer et al., 1999.3.29)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Inx2 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Inx2-RA FBtr0071005  NM_132147   2316   367 Inx2-RB FBtr0071006  NM_167104   2758   367 Inx2-RC FBtr0301860  NM_001169213   1832   367 Inx2-RD FBtr0332314  NM_001272372   5266   367
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Inx2-PA   FBpp0070965   42.5   367   6.24     NP_572375   AAF46229 Inx2-PB   FBpp0070966   42.5   367   6.24     NP_727150   AAN09193 Inx2-PC   FBpp0291074   42.5   367   6.24     NP_001162684   ACZ95220 Inx2-PD   FBpp0304593   42.5   367   6.24     NP_001259301   AGB95146
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Innexin (IPR000990)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141138   AA141139   AA202265   AA391730   AA392487   AA440979   AA441122   AA441601   AA735394   AA817328   AA949142   AA990689   AE014298 AAF46229   AE014298 AAN09193   AE014298 ACZ95220   AF137269 AAD50378   AF172257 AAF87943   AE014298 AGB95146   AI061897   AI061919   AI258295   AI455282   AI512683   AI515807   AI519440   AI543839   AI543923   AJ426733   AJ426735   AJ426736   AJ426737   AJ426741   AJ426743   AJ426744   AJ426745   AY060368 AAL25407   BF490768   BH146149   BI161899   BI161900   BI162028   BI162029   BI162534   BI162535   BI162536   BI162537   BI162828   BI162966   BI163034   BI163035   BI163112   BI163729   BI163857   BI164243   BI164272   BI165186   BI165734   BI166646   BI166917   BI167137   BI167830   BI167836   BI168327   BI168726   BI168927   BI169363   BI169817   BI169928   BI170113   BI170496   BI172073   BI172412   BI172710   BI172793   BI173185   BI173612   BI212283   BI212311   BI212770   BI212943   BI213119   BI213210   BI213392   BI213705   BI213728   BI213751   BI213904   BI213944   BI213971   BI214464   BI214650   BI214980   BI215724   BI216168   BI216638   BI228046   BI228243   BI228537   BI228541   BI228549   BI228810   BI228977   BI229412   BI229554   BI229617   BI229626   BI230514   BI231180   BI231818   BI232001   BI232169   BI232197   BI232631   BI232816   BI234221   BI234293   BI234355   BI234877   BI235515   BI235792   BI236220   BI236223   BI236321   BI236370   BI236944   BI237314   BI237799   BI238438   BI238699   BI239008   BI239348   BI239365   BI239459   BI240129   BI240464   BI240475   BI240691   BI241220   BI241243   BI241739   BI241810   BI242308   BI243124   BI243709   BI243731   BI355961   BI356000   BI356562   BI356681   BI356779   BI357403   BI357715   BI358280   BI358489   BI363184   BI363204   BI364193   BI364291   BI365047   BI365524   BI365600   BI365778   BI365877   BI366718   BI366847   BI366977   BI367219   BI368057   BI369868   BI370073   BI370580   BI371088   BI371475   BI371645   BI373001   BI373072   BI373738   BI373979   BI373987   BI374654   BI375149   BI375150   BI375158   BI375393   BI375594   BI483776   BI484061   BI484093   BI484111   BI484407   BI484748   BI484863   BI485116   BI485547   BI487070   BI571523   BI572260   BI572277   BI576340   BI577326   BI577656   BI577805   BI578566   BI578577   BI578785   BI579053   BI579162   BI579774   BI580270   BI580893   BI614988   BI623353   BI631568   BP542115   BP548505   BQ103647   CK657900   CK658159   CK659180   CK661473   CO178175   CO179012   CO179176   CO180191   CO180392   CO181263   CO185717   CO185749   CO187623   CO193199   CO194170   CO262522   CO262968   CO265122   CO265422   CO265608   CO265958   CO271039   CO274207   CO274514   CO277807   CO278950   CO279885   CO281009   CO284674   CO285886   CO285912   CO286075   CO287335   CO287882   CO288434   CO290717   CO292422   CO292858   CO295707   CO297956   CO302487   CO304291   CO306094   CO306599   CO306695   CO311744   CO312914   CO318466   CO319563   CO320208   CO321242   CO322406   CO323100   CO325416   CO325665   CO331234   CO332089   CO333682   CO339739   CZ473993   CZ475837   EC058447   EC061311   EC062836   EC063180   EC063452   EC064014   EC066471   EC068345   EC068434   EC068633   EC070457   EC070669   EC070670   EC075802   EC075813   EC076277   EC076728   EC077257   EC078290   EC080523   EC080604   EC082362   EC087242   EC087969   EC088031   EC196515   EC198121   EC198164   EC198989   EC201119   EC203281   EC204361   EC205407   EC206401   EC207867   EC209667   EC210227   EC211273   EC211956   EC212315   EC214403   EC214627   EC215580   EC215800   EC217002   EC218659   EC218924   EC221665   EC227376   EC227557   EC230904   EC231460   EC232932   EC234982   EC238513   EC240491   EC242048   EC243253   EC245779   EC246238   EC246903   EC249172   EC260778   EV580140   EV582579   EV584475   EV585716   EV587929   GH747673   GH747674   GH748572   GH749055   GH749549   GH750357   GH750446   GH750889   GH751240   GH752789   GH756058   GH757700   GH758550   GH759829   GH760286   GH774449   GH775413   GH776100   GH777826   GH778647   GH778966   GH779093   GH780056   GH780319   GH781339   GH782457   GH782625   GH783188   GH784173   GH784642   GH784729   GH786233   GH786624   GH787843   GH788198   GH790378   GH790493   GH790920   GH791824   GH792064   GH792807   GH792900   GH793625   GH793735   GH794476   GH795546   GH798515   GH800998   GH801962   GH803078   GH803804   GH804900   GH805038   GH805074   GH805158   GH805769   GH807284   GH807820   GH808688   GH809074   GH810939   GH810955   GH811248   GH812261   GH812596   GH813402   GH814221   GH815048   GH815546   GH816329   GH816387   GH816392   GH817630   GH817790   GH822120   GH822504   GH822970   GH823272   GH823792   GH824167   GH825316   GH825364   GH825456   GH826751   GH827422   GH827537   GH829101   GH830253   GH830565   GH833361   GH833396   GH833511   GH839733   GH839828   GH839945   GH840550   GH841277   GH841363   GH842342   GH842408   GH843493   GH843911   GH845375   GH845865   GH847650   GH848926   GH849002   GH850731   GH851974   GH854977   GH857064   GH857406   GH858991   GH862967   GH863537   GH864189   GH864795   GH865120   GH865632   GH865975   GH867671   GH867999   GH868293   GH868445   GH869310   GH869515   GH869572   GH870119   GH871150   GH871185   GH871758   GH871804   GH872008   GH874367   GH875527   GH876206   GH880157   GH880180   GH880545   GH880922   GH881769   GH882356   GH884415   GH885350   GH886011   GH886078   GH887269   GH887495   GH887497   GH887597   GH888028   GH888613   GH888970   GH893633   GH894588   GH897038   GH900272   GH903623   GH904073   GH905035   GH906831   GH907042   GH907833   GH907841   GH908603   GH908739   GH908871   GH910040   GH911510   GH911524   GH911804   GH912840   GH914458   GH915887   GH916322   GH917412   GH918204   GH918648   GH918696   GH919461   GH919577   GH919642   GH920255   GH920339   GH920388   GH920936   GH921551   GH921861   GH922489   GH926733   GH928201   GH928422   GH929279   GH929496   GH931016   GH931153   GH932317   GH934954   GH935655   GH936128   GH938466   GH938789   GH940940
UniProtKB/Swiss-Prot	Q9V427
UniProtKB/TrEMBL	E1JJF3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 5   embryonic cortex   (Curtin et al., 1999) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 8   cephalic furrow   (Curtin et al., 1999) germ band   (Curtin et al., 1999) embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal ectoderm   (Fisher et al., 2012) inclusive hindgut primordium   (Fisher et al., 2012) ventral ectoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalon primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalon primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalon primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalon primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalon primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalon primordium dorsal epidermis primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) tracheal primordium   (Fisher et al., 2012) ventral epidermis primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   atrium   (Fisher et al., 2012) embryonic dorsal epidermis   (Fisher et al., 2012) embryonic epipharynx   (Fisher et al., 2012) embryonic esophagus   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic head epidermis   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic hypopharynx   (Fisher et al., 2012) embryonic proventriculus   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval dorsal trunk   (Fisher et al., 2012) embryonic/larval posterior spiracle   (Fisher et al., 2012) embryonic stage 16 -- 17   embryonic/larval epidermis | segmentally repeated   (Curtin et al., 1999) embryonic/larval proventriculus   (Curtin et al., 1999) embryonic/larval foregut   (Curtin et al., 1999) embryonic/larval hindgut   (Curtin et al., 1999) adult stage   lamina   (Curtin et al., 1999)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
apical plasma membrane inferred from direct assay (Bohrmann and Zimmermann, 2008) apicolateral plasma membrane inferred from direct assay (Bohrmann and Zimmermann, 2008) gap junction inferred from direct assay (Bohrmann and Zimmermann, 2008, Stebbings et al., 2000) inferred from direct assay (assigned by UniProtKB) (Curtin et al., 1999)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval midgut, adult fat body, larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval salivary gland, adult female reproductive system, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    855.1 Larval Midgut    563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea    964.975 Larval Carcass    815.375 Adult Head    417.8 Adult Eye    401.7 Adult Brain    662.4 Adult Thoracic-Abdominal Ganglion    1004.6 Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body    506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (855.1) Larval Midgut  (563.2) Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea  (964.975) Larval Carcass  (815.375) Adult Head    417.8 Adult Eye    401.7 Adult Brain  (662.4) Adult Thoracic-Abdominal Ganglion  (1004.6) Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body  506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    855.1 Larval Midgut    563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea    964.975 Larval Carcass    815.375 Adult Head    417.8 Adult Eye    401.7 Adult Brain    662.4 Adult Thoracic-Abdominal Ganglion  1004.6 Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body    506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    855.1 Larval Midgut    563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea    964.975 Larval Carcass    815.375 Adult Head    417.8 Adult Eye    401.7 Adult Brain    662.4 Adult Thoracic-Abdominal Ganglion    1004.6 Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body    506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    855.1 Larval Midgut    563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea    964.975 Larval Carcass    815.375 Adult Head    417.8 Adult Eye    401.7 Adult Brain    662.4 Adult Thoracic-Abdominal Ganglion    1004.6 Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body    506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (855.1) Larval Midgut  563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea  (964.975) Larval Carcass  (815.375) Adult Head    417.8 Adult Eye    401.7 Adult Brain  662.4 Adult Thoracic-Abdominal Ganglion  (1004.6) Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body  506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    855.1 Larval Midgut    563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea    964.975 Larval Carcass    815.375 Adult Head    417.8 Adult Eye    401.7 Adult Brain    662.4 Adult Thoracic-Abdominal Ganglion  1004.6 Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body    506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    855.1 Larval Midgut    563.2 Larval Hindgut    412.2 Larval Malpighian Tubules    464.4 Larval Fat Body    78.2 Larval Salivary Gland    175.5 Larval Trachea    964.975 Larval Carcass    815.375 Adult Head    417.8 Adult Eye    401.7 Adult Brain    662.4 Adult Thoracic-Abdominal Ganglion    1004.6 Adult Crop    280.1 Adult Midgut    318.2 Adult Hindgut    199.7 Adult Malpighian Tubules    132.9 Adult Fat Body    506.3 Adult Salivary Gland    18.8 Adult Heart    160.55 Adult VirginFemale Spermatheca    140.8 Adult InseminatedFemale Spermatheca    121.3 Adult Ovary    448.9 Adult Testis    33.4 Adult Male Accessory Gland    80.1 Adult Carcass    209.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    417.8   NA  Eye    401.7   NA  Brain    662.4   855.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1004.6   NA  Crop    280.1   563.2  Midgut    318.2   412.2  Hindgut    199.7   464.4  Malpighian Tubules    132.9   78.2  Fat Body    506.3   175.5  Salivary Gland    no informative data   NA  Heart    160.55   964.975  Trachea    NA   NA  VirginFemale Spermatheca    140.8   NA  InseminatedFemale Spermatheca    121.3   NA  Ovary    448.9   NA  Testis    33.4   NA  Male Accessory Gland    80.1   815.375  Carcass    209.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    88 central nervous system, larvae L3    61 central nervous system, pupae P8    33 head, virgin 1-day female    40 head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female    28 head, mated 4-day female    27 head, mated 20-day female    11 head, mated 1-day male    36 head, mated 4-day male    38 head, mated 20-day male    27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    207 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering    81 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (88) central nervous system, larvae L3  (61) central nervous system, pupae P8  (33) head, virgin 1-day female  (40) head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female  (28) head, mated 4-day female  (27) head, mated 20-day female    11 head, mated 1-day male  (36) head, mated 4-day male  (38) head, mated 20-day male  (27) salivary gland, larvae L3 wandering    4 salivary gland, white prepupae  (207) digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering  (81) carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    88 central nervous system, larvae L3    61 central nervous system, pupae P8    33 head, virgin 1-day female    40 head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female    28 head, mated 4-day female    27 head, mated 20-day female    11 head, mated 1-day male    36 head, mated 4-day male    38 head, mated 20-day male    27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae  (207) digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering    81 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    88 central nervous system, larvae L3    61 central nervous system, pupae P8    33 head, virgin 1-day female    40 head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female    28 head, mated 4-day female    27 head, mated 20-day female    11 head, mated 1-day male    36 head, mated 4-day male    38 head, mated 20-day male    27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    207 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering    81 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    88 central nervous system, larvae L3    61 central nervous system, pupae P8    33 head, virgin 1-day female    40 head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female    28 head, mated 4-day female    27 head, mated 20-day female    11 head, mated 1-day male    36 head, mated 4-day male    38 head, mated 20-day male    27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    207 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering    81 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (88) central nervous system, larvae L3  (61) central nervous system, pupae P8  (33) head, virgin 1-day female  (40) head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female  28 head, mated 4-day female  27 head, mated 20-day female    11 head, mated 1-day male  (36) head, mated 4-day male  (38) head, mated 20-day male  27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae  (207) digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering  (81) carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    88 central nervous system, larvae L3    61 central nervous system, pupae P8    33 head, virgin 1-day female    40 head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female    28 head, mated 4-day female    27 head, mated 20-day female    11 head, mated 1-day male    36 head, mated 4-day male    38 head, mated 20-day male    27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae  (207) digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering    81 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    88 central nervous system, larvae L3    61 central nervous system, pupae P8    33 head, virgin 1-day female    40 head, virgin 4-day female    22 head, virgin 20-day female    12 head, mated 1-day female    28 head, mated 4-day female    27 head, mated 20-day female    11 head, mated 1-day male    36 head, mated 4-day male    38 head, mated 20-day male    27 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    207 digestive system, larvae L3 wandering    22 digestive system, 1-day adult    18 digestive system, 4-day adult    19 digestive system, 20-day adult    11 fat body, larvae L3 wandering    8 fat body, white prepupae    20 fat body, pupae P8    20 carcass, larvae L3 wandering    81 carcass, 1-day adult    16 carcass, 4-day adult    15 carcass, 20-day adult    9 ovary, virgin 4-day female    15 ovary, mated 4-day female    12 testis, mated 4-day male    3 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    159 embryo 04-06hr    326 embryo 06-08hr    276 embryo 08-10hr    280 embryo 10-12hr    276 embryo 12-14hr    192 embryo 14-16hr    117 embryo 16-18hr    79 embryo 18-20hr    51 embryo 20-22hr    44 embryo 22-24hr    46 larva L1    30 larva L2    35 larva L3 12hr old    24 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    81 white prepupae new    109 white prepupae 12hr    73 white prepupae 24hr    127 pupae 2d postWPP    66 pupae 3d postWPP    59 pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day    36 adult female 05day    34 adult female 30day    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (43) embryo 02-04hr  (159) embryo 04-06hr  (326) embryo 06-08hr  (276) embryo 08-10hr  (280) embryo 10-12hr  (276) embryo 12-14hr  (192) embryo 14-16hr  (117) embryo 16-18hr  (79) embryo 18-20hr  (51) embryo 20-22hr  (44) embryo 22-24hr  (46) larva L1  (30) larva L2  (35) larva L3 12hr old    24 larva L3 puffstage 1-2  (30) larva L3 puffstage 3-6  (55) larva L3 puffstage 7-9  (81) white prepupae new  (109) white prepupae 12hr  (73) white prepupae 24hr  (127) pupae 2d postWPP  (66) pupae 3d postWPP  (59) pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day  (36) adult female 05day  (34) adult female 30day  (31) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr  (159) embryo 04-06hr  (326) embryo 06-08hr  (276) embryo 08-10hr  (280) embryo 10-12hr  (276) embryo 12-14hr  (192) embryo 14-16hr  (117) embryo 16-18hr    79 embryo 18-20hr    51 embryo 20-22hr    44 embryo 22-24hr    46 larva L1    30 larva L2    35 larva L3 12hr old    24 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    81 white prepupae new  (109) white prepupae 12hr    73 white prepupae 24hr  (127) pupae 2d postWPP    66 pupae 3d postWPP    59 pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day    36 adult female 05day    34 adult female 30day    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    159 embryo 04-06hr    326 embryo 06-08hr    276 embryo 08-10hr    280 embryo 10-12hr    276 embryo 12-14hr    192 embryo 14-16hr    117 embryo 16-18hr    79 embryo 18-20hr    51 embryo 20-22hr    44 embryo 22-24hr    46 larva L1    30 larva L2    35 larva L3 12hr old    24 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    81 white prepupae new    109 white prepupae 12hr    73 white prepupae 24hr    127 pupae 2d postWPP    66 pupae 3d postWPP    59 pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day    36 adult female 05day    34 adult female 30day    31 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    159 embryo 04-06hr    326 embryo 06-08hr    276 embryo 08-10hr    280 embryo 10-12hr    276 embryo 12-14hr    192 embryo 14-16hr    117 embryo 16-18hr    79 embryo 18-20hr    51 embryo 20-22hr    44 embryo 22-24hr    46 larva L1    30 larva L2    35 larva L3 12hr old    24 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    81 white prepupae new    109 white prepupae 12hr    73 white prepupae 24hr    127 pupae 2d postWPP    66 pupae 3d postWPP    59 pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day    36 adult female 05day    34 adult female 30day    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (43) embryo 02-04hr  (159) embryo 04-06hr  (326) embryo 06-08hr  (276) embryo 08-10hr  (280) embryo 10-12hr  (276) embryo 12-14hr  (192) embryo 14-16hr  (117) embryo 16-18hr  (79) embryo 18-20hr  (51) embryo 20-22hr  (44) embryo 22-24hr  (46) larva L1  30 larva L2  (35) larva L3 12hr old    24 larva L3 puffstage 1-2  30 larva L3 puffstage 3-6  (55) larva L3 puffstage 7-9  (81) white prepupae new  (109) white prepupae 12hr  (73) white prepupae 24hr  (127) pupae 2d postWPP  (66) pupae 3d postWPP  (59) pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day  (36) adult female 05day  (34) adult female 30day  31 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr  (159) embryo 04-06hr  (326) embryo 06-08hr  (276) embryo 08-10hr  (280) embryo 10-12hr  (276) embryo 12-14hr  (192) embryo 14-16hr  117 embryo 16-18hr    79 embryo 18-20hr    51 embryo 20-22hr    44 embryo 22-24hr    46 larva L1    30 larva L2    35 larva L3 12hr old    24 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    81 white prepupae new  109 white prepupae 12hr    73 white prepupae 24hr  127 pupae 2d postWPP    66 pupae 3d postWPP    59 pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day    36 adult female 05day    34 adult female 30day    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    159 embryo 04-06hr    326 embryo 06-08hr    276 embryo 08-10hr    280 embryo 10-12hr    276 embryo 12-14hr    192 embryo 14-16hr    117 embryo 16-18hr    79 embryo 18-20hr    51 embryo 20-22hr    44 embryo 22-24hr    46 larva L1    30 larva L2    35 larva L3 12hr old    24 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    81 white prepupae new    109 white prepupae 12hr    73 white prepupae 24hr    127 pupae 2d postWPP    66 pupae 3d postWPP    59 pupae 4d postWPP    25 adult male 01day    23 adult male 05day    15 adult male 30day    10 adult female 01day    36 adult female 05day    34 adult female 30day    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3    59 leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21    30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    86 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS    29 ovary OSC    36 ovary OSS    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3  (59) leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21  (30) wing disc ML-DmD32    14 haltere disc ML-DmD17-c3  (86) eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS  (29) ovary OSC  (36) ovary OSS  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3    59 leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21    30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    86 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS    29 ovary OSC    36 ovary OSS    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3    59 leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21    30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    86 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS    29 ovary OSC    36 ovary OSS    53 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3    59 leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21    30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    86 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS    29 ovary OSC    36 ovary OSS    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3  (59) leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21  30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3  (86) eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS  29 ovary OSC  (36) ovary OSS  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3    59 leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21    30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    86 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS    29 ovary OSC    36 ovary OSS    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    14 embryonic 1182-4H    1 embryonic GM2    21 embryonic Kc167    2 embryonic S1    8 embryonic S3    59 leg disc CME L1    9 wing disc CME-W2    16 wing disc ML-DmD8    21 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    3 wing disc ML-DmD21    30 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    86 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    2 ovary fGS/OSS    29 ovary OSC    36 ovary OSS    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3  (42) Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3  26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3  (27) Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3  (42) Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3  26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3  27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    13 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    19 Cadmium 100 mM 48 hrs, 4-day adult    11 Copper 0.5 mM 12 hrs, larvae L3    22 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    8 Ethanol 5% 3 hrs, larvae L3    26 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    20 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    11 Rotenone 2 μg 12 hrs, larvae L3    27 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • LD22570 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027108 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4590-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Inx2 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Dcr-2Scer\UAS.cDa, Scer\GAL4e22c, Scer\GAL4sqh.PW Inx2KK111067 lethal, with Scer\GAL4elav-C155 Inx2Scer\UAS.cCa lethal | embryonic stage Inx2G0016 Inx2G0034 Inx2G0364 lethal | embryonic stage | recessive Inx2G0016 Inx2G0034 Inx2G0036 Inx2G0188 lethal | female Inx2G0317 lethal | larval stage Inx2G0016 Inx2G0034 Inx2G0036 Inx2G0043 Inx2G0059 Inx2G0118 Inx2G0188 lethal | larval stage | recessive Inx2G0016 Inx2G0034 Inx2G0036 Inx2G0188 lethal | partially, with Scer\GAL4arm.PS Inx2Scer\UAS.cSa lethal | partially, with Scer\GAL4how-24B Inx2Scer\UAS.cSa lethal | pupal stage Inx2G0035 lethal | recessive Inx2G0035 Inx2G0059 Inx2G0118 Inx2G0157 Inx2G0317 Inx2G0364 Inx2PG4 Inx2PG46 Inx2PG55 Inx2PG57 Inx2PG71 Inx2PG73 Inx2PG81 Inx2PG92 Inx2PG104 Inx2PG109 Inx2PG144 Inx2PG160 Inx2PL19 partially lethal - majority die | recessive Inx2G0036 Inx2G0043 viable Inx2BG02251 viable, with Scer\GAL4pnr-MD237 Inx2GD3267 Sterility Allele female sterile (with Inx2FA42) Inx2G0118 female sterile (with Inx2G0118) Inx2FA42 female sterile | recessive Inx2FA42 Other Phenotypes Allele cell shape defective Inx2G0016 feeding behavior defective | larval stage Inx2G0016 Inx2G0034 Inx2G0036 Inx2G0188 increased cell death | embryonic stage, with Scer\GAL4mat.αTub67C.T:Hsim\VP16 Inx2Scer\UAS.cBa increased cell death | embryonic stage | rescuable maternal effect Inx2G0016 small body | embryonic stage Inx2G0016 smell perception defective Inx2BG02251 visible, with Scer\GAL4pnr-MD237 Inx2GD3267 Phenotype manifest in Allele egg chamber Inx2FA42 embryonic/first instar larval cuticle | rescuable maternal effect Inx2G0016 embryonic/larval proventriculus Inx2G0016 embryonic epidermis, with Scer\GAL4mat.αTub67C.T:Hsim\VP16 Inx2Scer\UAS.cBa embryonic epidermis | rescuable maternal effect Inx2G0016 embryonic foregut Inx2G0016 embryonic head Inx2G0016 embryonic hindgut Inx2G0016 embryonic Malpighian tubule Inx2G0016 embryonic segment Inx2G0016 female germline cell, with Scer\GAL4C587 Inx2NIG.4590R Inx2KK111067 germarium, with Scer\GAL4C587 Inx2NIG.4590R Inx2KK111067 ovary Inx2FA42 ovary, with Scer\GAL4C587 Inx2NIG.4590R Inx2KK111067 ovary (with Inx2FA42) Inx2G0118 ovary (with Inx2G0118) Inx2FA42 presumptive embryonic/larval tracheal system Inx2G0016 presumptive embryonic salivary gland Inx2G0016 proventriculus primordium Inx2G0016 trichogen cell, with Scer\GAL4pnr-MD237 Inx2GD3267
Classical Alleles ( 34 )
For All Classical Alleles Show
Allele of Inx2 Class Mutagen Stocks Known lesion Inx2G0059 P-element activity 2 -- Inx2G0157 P-element activity 2 -- Inx2G0173a P-element activity 2 -- Inx2G0317 P-element activity 2 -- Inx2G0118 amorphic allele - molecular evidence P-element activity 1 -- Inx2BG02429 P-element activity 1 -- Inx2G0035 P-element activity 1 -- Inx2G0036 P-element activity 1 Yes Inx2G0043 P-element activity 1 -- Inx2G0090a P-element activity 1 -- Inx2NP5024 1 -- Inx2NP6052 1 -- Inx2NP7155 1 -- Inx2BG02251 0 Yes Inx2d04552 P-element activity 0 -- Inx2d07613 P-element activity 0 -- Inx2FA42 hypomorphic allele - molecular evidence ethyl methanesulfonate 0 Yes Inx2G0016 loss of function allele P-element activity 0 Yes Inx2G0034 P-element activity 0 Yes Inx2G0188 P-element activity 0 Yes Inx2G0364 P-element activity 0 -- Inx2PG104 Delta2-3 0 -- Inx2PG109 Delta2-3 0 -- Inx2PG144 Delta2-3 0 -- Inx2PG160 Delta2-3 0 -- Inx2PG46 Delta2-3 0 -- Inx2PG4 Delta2-3 0 -- Inx2PG55 Delta2-3 0 -- Inx2PG57 Delta2-3 0 -- Inx2PG71 Delta2-3 0 -- Inx2PG73 Delta2-3 0 -- Inx2PG81 Delta2-3 0 -- Inx2PG92 Delta2-3 0 -- Inx2PL19 Delta2-3 0 --
Alleles Carried on Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Inx2 Class Mutagen Stocks Known lesion Inx2HMS02481 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Inx2JF02446 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Inx2KK111067 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Inx2GD3267 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Inx2HM05126 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Inx2NIG.4590R in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes Inx2Scer\UAS.cBa in vitro construct - regulatory fusion 0 Yes Inx2Scer\UAS.cCa in vitro construct - regulatory fusion 0 Yes Inx2Scer\UAS.cSa in vitro construct - regulatory fusion 0 Yes Inx2Scer\UAS.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Sxl-bt (Mukai et al., 2011)
Duplicated in	Dp(1;3)DC489 (Popodi et al., 2010-)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.HMS02481} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}Inx7EP1309 NA P{EP}Inx7EP1546 NA P{EP}Inx7EP1641 NA P{XP}Inx2d04552 NA P{XP}Inx2d07613 NA insertion of enhancer trap binary system P{GawB}Inx2NP5024 No P{GawB}Inx2NP6052 No P{GawB}Inx2NP7155 No P{GawB}Inx2PG4 No P{GawB}Inx2PG46 No P{GawB}Inx2PG55 No P{GawB}Inx2PG57 No P{GawB}Inx2PG71 No P{GawB}Inx2PG73 No P{GawB}Inx2PG81 No P{GawB}Inx2PG92 No P{GawB}Inx2PG104 No P{GawB}Inx2PG109 No P{GawB}Inx2PG144 No P{GawB}Inx2PG160 No miscellaneous insertions P{GT1}Inx2BG02251 NA P{GT1}Inx2BG02429 NA insertion of enhancer trap P{lacW}Inx2G0016 No P{lacW}Inx2G0034 No P{lacW}Inx2G0035 No P{lacW}Inx2G0036 No P{lacW}Inx2G0043 No P{lacW}Inx2G0059 No P{lacW}Inx2G0090a No P{lacW}Inx2G0118 No P{lacW}Inx2G0157 No P{lacW}Inx2G0173a No P{lacW}Inx2G0188a No P{lacW}Inx2G0188b No P{lacW}Inx2G0317 No P{lacW}Inx2G0364 No P{lacW}Inx2PL19 No P{lacW}l(1)G0011G0011 No
Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )
Terms Based on Experimental Evidence ( 11 terms )
Molecular Function
CV term Evidence References
gap junction channel activity inferred from direct assay (Stebbings et al., 2000)
Biological Process
CV term Evidence References
cell communication inferred from direct assay (Bohrmann and Zimmermann, 2008) foregut morphogenesis inferred from mutant phenotype (Bauer et al., 2002) germarium-derived egg chamber formation inferred from mutant phenotype (Mukai et al., 2011) germarium-derived female germ-line cyst formation inferred from mutant phenotype (Mukai et al., 2011) intercellular transport inferred from direct assay (Stebbings et al., 2000) morphogenesis of embryonic epithelium inferred from mutant phenotype (Bauer et al., 2004) olfactory behavior inferred from mutant phenotype (Sambandan et al., 2006)
Cellular Component
CV term Evidence References
apical plasma membrane inferred from direct assay (Bohrmann and Zimmermann, 2008) apicolateral plasma membrane inferred from direct assay (Bohrmann and Zimmermann, 2008) gap junction inferred from direct assay (Bohrmann and Zimmermann, 2008, Stebbings et al., 2000) inferred from direct assay (assigned by UniProtKB) (Curtin et al., 1999)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
gap junction channel activity inferred by curator from GO:0005921 (Bohrmann and Zimmermann, 2008)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
gap junction inferred from sequence or structural similarity with EMBL:AF115854 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Inx2 allele Gene References inx2Scer\UAS.cSa Inx3 (Stebbings et al., 2000)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58124 DroID - A comprehensive database of gene and protein interactions. • FBgn0027108 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31646
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6ZCTQH Dipteran inclusive ortholog search EOG6TXC1J Insect inclusive ortholog search EOG64B8XV Arthropod inclusive ortholog search EOG60VT55 Metazoa inclusive ortholog search EOG65XMPR
Orthologs in Drosophila Species (EOG6ZCTQH)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Inx2     Drosophila simulans   Dsim\GD16826 Y   Drosophila sechellia   Dsec\GM17498 Y   Drosophila erecta   Dere\GG19626 Y   Drosophila yakuba   Dyak\GE15694 Y   Drosophila ananassae   Dana\GF20357 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18281 Y   Drosophila persimilis   Dper\GL26820 Y   Drosophila willistoni   Dwil\GK25636 Y   Drosophila virilis   Dvir\GJ15793 Y   Drosophila mojavensis   Dmoj\GI21669 Y   Drosophila grimshawi   Dgri\GH24686 Y
Orthologs in non-Drosophila Dipterans (EOG6TXC1J)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014847   Anopheles gambiae Malaria mosquito  Agam\AGAP001488   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ014809
Orthologs in non-Dipteran Insects (EOG64B8XV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\inx2   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG015812   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16154   Atta cephalotes Leafcutter ant  Acep\ACEP18357   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16607   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12400   Linepithema humile Argentine ant  Lhum\LH12525   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21401   Solenopsis invicta Red fire ant  Sinv\SINV20567   Solenopsis invicta Red fire ant  Sinv\SINV18118   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009441   Bombyx mori Silkmoth  Bmor\BGIBMGA007629   Pediculus humanus Human body louse  Phum\PHUM291320   Tribolium castaneum Red flour beetle  Tcas\TC011417
Orthologs in non-Insect Arthropods (EOG60VT55)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\L5   Daphnia pulex Water flea  Dpux\COI   Ixodes scapularis Deer tick  Isca\ISCW015171   Ixodes scapularis Deer tick  Isca\ISCW013696   Ixodes scapularis Deer tick  Isca\ISCW002903
Orthologs in non-Arthropod Metazoa (EOG65XMPR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\inx-19 Y Caenorhabditis elegans Nematode  Cele\inx-22 Y Caenorhabditis elegans Nematode  Cele\inx-18 Y Caenorhabditis elegans Nematode  Cele\inx-11 Y Caenorhabditis elegans Nematode  Cele\inx-2 Y Caenorhabditis elegans Nematode  Cele\inx-5 Y Caenorhabditis elegans Nematode  Cele\inx-7 Y Caenorhabditis elegans Nematode  Cele\inx-3 Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD16826 Drosophila sechellia Dsec\GM17498 Drosophila erecta Dere\GG19626 Drosophila yakuba Dyak\GE15694 Drosophila ananassae Dana\GF20357 Drosophila pseudoobscura pseudoobscura Dpse\GA18281 Drosophila persimilis Dper\GL26820 Drosophila willistoni Dwil\GK25636 Drosophila virilis Dvir\GJ15793 Drosophila mojavensis Dmoj\GI21669 Drosophila grimshawi Dgri\GH24686
Stocks & Reagents
Stocks Listed in FlyBase ( 20 )
Bloomington	29306 y1 v1; P{TRiP.JF02446}attP2 11517 w67c23 P{lacW}Inx2G0035/FM7c 11519 w67c23 P{lacW}Inx2G0036/FM7c 11550 w67c23 P{lacW}Inx2G0043/FM7c 11826 w67c23 P{lacW}Inx2G0118/FM7c 11856 w67c23 P{lacW}Inx2G0059/FM7c 11857 w67c23 P{lacW}Inx2G0317/FM7c 11941 w67c23 P{lacW}Inx2G0157/FM7c 12834 w1118 P{GT1}Inx2BG02429/FM7c
Kyoto	114106 w* P{GawB}Inx2NP7155 / FM7c 104809 y* w* P{GawB}Inx2NP5024 / FM7c
VDRC	v102194 P{KK111067}VIE-260B
	More stocks available...
Genomic Clones ( 1 )
	BACR17C09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 521 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD22570
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT27345 LD02386 LD11362 LD11658 LD16581 LD27927 LD34958 LD41479 LD45611 LP14787 LP16757 LP21007 RE02435 RE03214 RE07163 RE07457 RE08310 RE11244 RE14208 RE14889 RE16565 RE17342 RE17378 RE19244 RE20280 RE20624 RE22320 RE23106 RE25191 RE26102 RE26107 RE26456 RE26654 RE27185 RE27435 RE27446 RE28730 RE29135 RE30038 RE32251 RE34909 RE35217 RE35387 RE35818 RE35837 RE36778 RE37076 RE37314 RE37326 RE38244 RE38982 RE39607 RE41426 RE41451 RE42740 RE42872 RE42985 RE43876 RE45266 RE47938 RE47963 RE49371 RE50266 RE50868 RE50961 RE51271 RE52468 RE52635 RE52933 RE56195 RE56461 RE57908 RE58573 RE60210 RE60284 RE61130 RE61466 RE61476 RE62901 RE63176 RE66715 RE67146 RE67502 RE67895 RE68029 RE68395 RE68903 RE70575 RE70988 RE71553 RE72447 RE72459 RE72709 RE73026 RE73148 RE73855 RE75140
Other clones	12386 13000 28492 30080 31589 31829 32781 34530 53479 53753 59295 59750 62201 63336 64164 69153 69916 70130 71748 77075 81621 82178 82360 102521 105540 106184 108350 120329 125149 144246 144312 144638 160710 161518 166005 167203 172471 174599 177540 214385.9 282139 CK01.4C.C11 CK01.8D.D4 CK01.9D.H6 CK01.28A.C2 CK01.36B.A2 CK01.41B.F10 CK01.73D.G8 CK01.74D.G10 CK01.78C.E2 CK01.84C.B6 CK01.86D.D11 CK01.96C.A4 CK01.97D.B6 CK01.101C.G2 CK01.103C.C6 CK01.110D.D4 CK01.112C.G1 CK01.117C.D2 CK01.131A.F1 CK01250 Dmel_dig_004210_0599_2174 Dmel_dig_006694_0668_3144 Dmel_dig_011800_0664_2650 Dmel_dig_020951_0583_1532 Dmel_neb_013559_0115_1665 EC01191 EC01491 EC13917 EC35276 EC37554 EK011119 EK011446 EK030925 EK055563 EK058160 EK058659 EK061103 EK061149 EK061637 EK065563 EK067030 EK068514 EK074934 EK085643 EK086943 EK101646 EK113541 EK114321 EK126508 EK132404 EK136311 EK141559 EK142625 EK143212 EK144553 EK155719 EK166531 EK171012 EK184252 EK188052 EK189658 EK196447 EK197047 EK200143 EK201109 EK211363 EK226048 EK230539 EK244258 EK250244 EK251542 EK251921 EK272246 EK279162 EK282735 EK290553 EK298855 EK302504 EK307658 EP22441 FGC009C04 FGH128E04 LD10313 LD16015 LD21239 LD34511 LD34992 LD39042 LD39929 LD44625 LP01447 RE01367 RE01458 RE01823 RE01824 RE02068 RE02249 RE02329 RE02330 RE03375 RE03875 RE03920 RE05020 RE05679 RE06841 RE08318 RE09035 RE09575 RE09837 RE10516 RE11102 RE11470 RE11969 RE14013 RE15367 RE15469 RE15947 RE18015 RE18222 RE18447 RE18565 RE18779 RE19166 RE19212 RE19543 RE19595 RE19636 RE20405 RE21155 RE23843 RE24352 RE25463 RE25718 RE26119 RE27360 RE28187 RE28224 RE28939 RE29883 RE29975 RE30646 RE31369 RE31720 RE32254 RE32361 RE32420 RE33078 RE33526 RE34116 RE35945 RE37031 RE37602 RE38268 RE38885 RE40681 RE44263 RE45005 RE49257 RE51157 RE52314 RE53966 RE57261 RE58373 RE62301 RE62887 RE62888 RE63438 RE67093 RE67127 RE71367 RE74434 RH06663 RH07736 RH07753 RH32880 RH44495 RH55491 RH61162 RP003000214 RP003004786 RP003008161 RP003018649 RP003025005 RP003029638 RP003034808 RP003048312 RP003060246 RP003061145 RP003062371 RP003062909 RP003075657 RP003076905 RP003077232 RP003080491 RP003087349 RP003089673 RP003094859 RP003095861 RP003098754 RP003100335 RP003102452 RP003110397 RP003112759 RP003115521 RP003116434 RP003121903 RP003128636 RP003130233 RP003134143 RP003134241 RP003135856 RP003138857 RP003139997 RP003144419 RP003147729 RP003152659 RP003153685 RP003155566 RP003159679 RP003160239 RP003164909 RP003172652 RP003172935 RP003178140 RP003178403 RP003178425 RP003179594 RP003185373 RP003185511 RP003186257 RP003189078 RP003191518 RP003191843 RP003193143 RP003195889 RP003199958 RP003202226 RP003204974 RP003216607 RP003216611 RP003222067 RP003230342 RP003232173 RP003235385 RP003238634 RP003241500 RP003243347 RP003245023 RP003245434 RP003246229 RP003255897 RP003256211 RP003257326 RP003257706 RP003259160 RP003261160 RP003262107 RP003263316 RP003264119 RP003265808 RP003265826 RP003267412 RP003267698 RP003270482 RP003277025 RP003277098 RP003278011 RP003279663 RP003281380 RP003282004 RP003284329 RP003286920 RP003287532 RP003287755 RP003288184 RP003289297 RP003292514 RP003293632 RP003294899 RP003295874 RP003295896 RP003298852 RP003299158 RP003300775 RP003302767 RP003306563 RP003311379 RP003312615 RP003315202 RP003316454 RP003318838 RP003321628 RP003322320 RP003326491 RP003331877 RP003332426 RP003332700 RP003335452 RP003338802 RP003343514 RP003346009 RP003349212 RP003360382 RP003363271 RP003368986 RP003386317 RP003386627 RP003391368 RP003403316 RP003410984 RP003412060 RP003413658 RP003415119 RP003417122 RP003417190 RP003419535 RP003421641 RP003425940 RP003426143 RP003430787 RP003432530 RP003441827 RP003441915 RP003441970 RP003444664 RP003446029 RP003463640 RP003470733 RP003477523 RP003477779 RP003483040 RP003484775 RP003488023 RP003495828 RP003501178 RP003501295 RP003502286 RP003503526 RP003504269 RP003508710 RP003517061 RP003517499 RP003520956 RP003522855 RP003527778 RP003527936 RP003528710 RP003529176 RP003529187 RP003530047 RP003530861 RP003532374 RP003534522 RP003536751 RP003538806 RP003543638 RP003545686 RP003546045 RP003546578 RP003547349 RP003549998 RP003553661 RP003558247 RP003559524 RP003574856 RP003588124 RP003589783 RP003599284 RP003602138 RP003611182 RP003618482 RP003618868 RP003626849 RP003638871 RP003647343 RP003655014 RP003656847 RP003668434 RP003671064 RP003674319 RP003677913 UUGC1057
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027108 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31646
Antibody Information
	polyclonal (Bohrmann and Zimmermann, 2008)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Inx2 inx2 (FlyBase, 2009-)
Source for database merge of	Source for merge of: inx2 l(1)G0036 (Bauer et al., 2002) Source for merge of: inx2 l(1)G0036 l(1)G0317 l(1)G0035 l(1)G0157 l(1)G0059 l(1)G0118 l(1)G0043 l(1)G0364 (Peter et al., 2002)
Additional comments	"l(1)G0011" may affect "inx2". (Peter et al., 2002)
Other Comments
	inx2 is required for the normal formation of the keyhole, a primordial structure of the proventriculus. (Bauer et al., 2002)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132147 NM_167104 NM_001169213 NM_001272372 RefSeq (Proteins) • NP_572375 NP_727150 NP_001162684 NP_001259301 DDBJ / EMBL / GenBank • AA392487 AA817328 AAD50378 AAF46229 AAF87943 AAL25407 AAN09193 ACZ95220 AF137269 AF172257 AGB95146 AI455282 AJ426733 AJ426735 AJ426736 AJ426737 AJ426741 AJ426743 AJ426744 AJ426745 AY060368 BH146149 CZ473993 CZ475837 Entrez Gene - A searchable database of RefSeq genes. • 31646 UniProtKB/Swiss-Prot • Q9V427 UniProtKB/TrEMBL • E1JJF3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Innexin (IPR000990) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD22570
Linkouts
	BioGRID - A database of protein and genetic interactions • 58124 DroID - A comprehensive database of gene and protein interactions. • FBgn0027108 DRSC - Results from RNAi screens. • FBgn0027108 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027108 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4590-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027108 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31646 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31646 modMine - Data generated by the modENCODE project. • FBgn0027108
Synonyms & Secondary IDs ( 26 )
Reported As
Symbol Synonym	CG4590 (Bourbon et al., 2002, Quinones-Coello, 2007, Keleman et al., 2009.8.5, Perkins et al., 2009, Cammarato et al., 2011, Ni et al., 2010.12.1, Tsubouchi et al., 2012) D-inx-2 (Curtin et al., 2002) Dm-inx (Lehmann et al., 2001) Dm-inx2 (Phelan and Starich, 2001, Stebbings et al., 2000) FBpp0291074 (Abascal and Zardoya, 2013) inx-2 (Chiusano et al., 2005, Tazuke et al., 2002) Inx2 (Brody et al., 2002, Bohrmann and Zimmermann, 2008, Kim et al., 2005, ) INX-2 (Wei et al., 2005) inx2 (Mukai et al., 2011, Tsubouchi et al., 2012, Reiter et al., 2007, Lehmann et al., 2006, Quinones-Coello, 2007, Lechner et al., 2007, Quijano et al., 2008, Popodi et al., 2010-, Wu et al., 2011, Ayukawa et al., 2012) Ix2 (Davies, 1999.9.16, Stebbings et al., 1999) kropf (Bauer et al., 2002, Lechner et al., 2007) l(1)G0035 (Schaefer et al., 1999.6.15, Schaefer et al., 1999.3.29, ) l(1)G0036 (Schaefer et al., 1999.6.15, ) l(1)G0043 (Schaefer et al., 1999.6.15, Schaefer et al., 1999.3.29, ) l(1)G0059 (Schaefer et al., 1999.3.29, ) l(1)G0118 (Schaefer et al., 1999.6.15, Schaefer et al., 1999.3.29, ) l(1)G0157 (Schaefer et al., 1999.8.12, ) l(1)G0317 (Schaefer et al., 1999.6.15, ) l(1)G0364 (Schaefer et al., 1999.12.14, ) prp33 (Curtin, 1999.3.25, Davies and Curtin, 1999.9.30, Curtin et al., 1999, )
Name Synonym	Innexin (Wei et al., 2005) innexin2 (Lehmann et al., 2006, Mukai et al., 2011, Lechner et al., 2007) Innexin-2 (Abascal and Zardoya, 2013) innexin 2 (Cammarato et al., 2011, Tsubouchi et al., 2012, Sambandan et al., 2008, Bauer et al., 2003, Goulding et al., 2004, Ostrowski et al., 2005, Sambandan et al., 2006, Bohrmann and Zimmermann, 2008) Innexin 2   pas related protein 33 (Curtin et al., 1999)
Secondary FlyBase IDs
	FBgn0026672 FBgn0026693 FBgn0026703 FBgn0026707 FBgn0027220 FBgn0027325 FBgn0028356 FBgn0029062
References ( 69 )
Generate a list of	All references relating to this gene ( 69 )
List References by type	Research paper  ( 26 ) Supplementary material  ( 9 ) Review  ( 2 ) Personal communication to FlyBase  ( 13 ) Abstract  ( 10 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 2 ) Website  ( 1 ) Curated genome annotation  ( 2 ) Protein sequence record  ( 1 )
Recent research papers ( 3 )
	Ayukawa et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(38): 15318--15323 Rescue of Notch signaling in cells incapable of GDP-L-fucose synthesis by gap junction transfer of GDP-L-fucose in Drosophila. [FBrf0219480] Mukai et al., 2011, Mech. Dev. 128(7-10): 510--523 Innexin2 gap junctions in somatic support cells are required for cyst formation and for egg chamber formation in Drosophila. [FBrf0216750] Wu et al., 2011, Curr. Biol. 21(10): 848--854 Heterotypic Gap Junctions between Two Neurons in the Drosophila Brain Are Critical for Memory. [FBrf0213804] Show all research papers ...
Recent reviews ( 1 )
	Abascal and Zardoya, 2013, Biochim. Biophys. Acta 1828(1): 4--14 Evolutionary analyses of gap junction protein families. [FBrf0219962] Show all reviews ...