A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Gene Dmel\l(1)G0003

General Information
SymbolDmel\l(1)G0003SpeciesD. melanogaster
Namelethal (1) G0003Annotation symbolCG6606
Feature typeprotein_coding_geneFlyBase IDFBgn0027335
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)XRecombination map1-
Cytogenetic map 17C6-17C7 Sequence locationX:18,529,667..18,541,596 [-]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene lethal (1) G0003 is referred to in FlyBase by the symbol l(1)G0003 (CG6606, FBgn0027335). It has the cytological map location 17C6-17C7. Its sequence location is X:18529667..18541596. Its molecular function is unknown. The biological processes in which it is involved are not known. 29 alleles are reported. The phenotype of these alleles is annotated with pupa. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
17C6-17C7  
Limits computationally determined from genome sequence between P{EP}EP443EP443&P{EP}BxEP1383 and P{EP}Pk17EEP438  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
17D-17D
(determined by in situ hybridisation) 17C--D (determined by in situ hybridisation) 17C5--7 (determined by in situ hybridisation) 17C1--2 (determined by in situ hybridisation)  
(Peter et al., 2002)
17C-17D
(determined by in situ hybridisation) 17D (determined by in situ hybridisation)  
(Schaefer et al., 1999.12.2)
17C-17D
(determined by in situ hybridisation)  
(Schaefer et al., 1999.12.14)
17D-17D
(determined by in situ hybridisation)  
(Schaefer et al., 1999.8.12)
17C-17D
(determined by in situ hybridisation) 17C1--2 (determined by in situ hybridisation) 17C (determined by in situ hybridisation)  
(Schaefer et al., 1999.6.15)
Experimentally Determined Recombination Data
Location
1-
(Schaefer et al., 1999.6.15)
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\l(1)G0003 for information on other features
detailed view FBtr0074617 FBtr0074616 FBtr0074601 FBtr0074615 FBpp0074387 FBpp0074372 FBpp0074386 FBti0015670 FBti0013322 FBti0071703 FBti0038217 FBti0012883 FBti0056914 FBti0021709 FBti0034115 FBti0068479 FBti0053939 FBti0013233 FBti0013217 FBti0071210 FBti0018412 FBti0100044 FBti0048784 FBti0075604
Comments on Gene Model
DGC clone appears problematic (GM01994): incomplete CDS.
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
l(1)G0003-RA
FBtr0074616
 NM_133085
  3812
  832
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
l(1)G0003-PA  
FBpp0074387  
91.9  
832  
6.19  
  NP_573313
  AAF48865
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
C2 calcium-dependent membrane targeting (IPR000008)
C2 calcium/lipid-binding region, CaLB (IPR008973)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA264704
 
AA567324
 
AA695048
 
AA801672
 
AE003509
AAF48865
 
AI064092
 
AI109987
 
AI134636
 
AI259569
 
AI259837
 
AI402858
 
AJ426981
 
AJ426984
 
AJ426985
 
AJ426986
 
AJ426987
 
AW941163
 
AY060838
AAL28386
 
BF492281
 
BF493956
 
BG633853
 
BG635983
 
BG637245
 
BH759334
 
BH759335
 
BI164037
 
BI167396
 
BI216690
 
BI227955
 
BI236404
 
BI240285
 
BI241023
 
BI357712
 
BI632926
 
BI633892
 
BP546209
 
BT023794
 
CO153503
 
CO153836
 
CO156494
 
CO271179
 
CO293331
 
CO305875
 
CO310808
 
CO320531
 
CO325551
 
CO328042
 
CO335794
 
CO337623
 
CO341084
 
CO343205
 
CZ471443
 
CZ471840
 
CZ471841
 
CZ476864
 
EC052187
 
EC064727
 
EC065999
 
EC071561
 
EC075420
 
EC084233
 
EC200986
 
EC216082
 
EC254177
 
EC255920
 
EC257342
 
EC262156
 
EC264550
 
EC264589
 
EC267026
 
EC267734
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Microarray Data
        Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)
        Untitled Document detailed view FBtr0074617 FBtr0074616 FBtr0074601 FBtr0074615
        AI064544
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Lethality
        Allele
        lethal | recessive
        lethal | larval stage
        lethal | prepupal stage
        lethal | pupal stage
        lethal | adult stage
        lethal | pharate adult stage
        semi-lethal | recessive
        semi-lethal | male
        semi-lethal | female
        Phenotype manifest in
        Allele
        pupa
        hide Classical Alleles ( 15 )
        For All Classical Alleles Show

        Allele of l(1)G0003ClassMutagenStocksKnown lesion
        l(1)G0003G00031 --
        l(1)G0003G00701 --
        l(1)G0003G00921 --
        l(1)G0003G02051 --
        l(1)G0003G02971 --
        l(1)G0003G04260 --
        l(1)G0003G0434b1 --
        l(1)G0003KG024851 --
        l(1)G0003PG1030 --
        l(1)G0003PL120 --
        l(1)G0003PL55#10 --
        l(1)G0003PL720 --
        l(1)G0003d001901 --
        l(1)G0003d008460 --
        l(1)G0003d096581 --
        hide Alleles Carried on Transgenic Constructs ( 14 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of l(1)G0003ClassMutagenStocksKnown lesion
        l(1)G0003GD119750 Yes
        l(1)G0003dsRNA.1351-15210 --
        l(1)G0003dsRNA.1351-18610 --
        l(1)G0003dsRNA.1522-17720 --
        l(1)G0003dsRNA.1522-18120 --
        l(1)G0003dsRNA.1773-18120 --
        l(1)G0003dsRNA.1773-20280 --
        l(1)G0003dsRNA.1783-20280 --
        l(1)G0003dsRNA.1862-22200 --
        l(1)G0003dsRNA.22-3600 --
        l(1)G0003dsRNA.2483-28470 --
        l(1)G0003dsRNA.3133-37350 --
        l(1)G0003dsRNA.361-9570 --
        l(1)G0003dsRNA.958-13500 --
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        Disrupted in
        (Ryder, 2004.4.26)
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD11975}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        insertion of mobile activating element
        P{XP}l(1)G0003d00190
        NA
        P{XP}l(1)G0003d00846
        NA
        P{XP}l(1)G0003d09658
        NA
        miscellaneous insertions
        P{SUPor-P}l(1)G0003KG02485
        NA
        insertion of enhancer trap binary system
        P{GawB}l(1)G0003PG103
        No
        insertion of enhancer trap
        P{lacW}l(1)G0003G0003
        No
        P{lacW}l(1)G0003G0070
        No
        P{lacW}l(1)G0003G0092
        No
        P{lacW}l(1)G0003G0205
        No
        P{lacW}l(1)G0003G0297
        No
        P{lacW}l(1)G0003G0426
        No
        P{lacW}l(1)G0003G0434b
        No
        P{lacW}l(1)G0003PG103
        No
        P{lacW}l(1)G0003PL12
        No
        P{lacW}l(1)G0003PL55#1
        No
        P{lacW}l(1)G0003PL72
        No
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 0 )
        hide Molecular Function
        CV term
        Evidence
        References
        hide Biological Process
        CV term
        Evidence
        References
        hide Cellular Component
        CV term
        Evidence
        References
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        l(1)G0003 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 9 )
        Harvard
        -
        P{XP}l(1)G0003d00190
        -
        P{XP}l(1)G0003d09658
        Bloomington
        11466
        w67c23 P{lacW}l(1)G0003G0003/FM7c
        11727
        w67c23 P{lacW}l(1)G0003G0070/FM7c
        11810
        w67c23 P{lacW}l(1)G0003G0092/FM7c
        11893
        w67c23 P{lacW}l(1)G0003G0205/FM7c
        12237
        w67c23 P{lacW}l(1)G0003G0297/FM7c
        12026
        w67c23 P{lacW}l(1)G0003G0434b/FM7c
        13742
        y1 P{SUPor-P}l(1)G0003KG02485/FM7c
        hide Genomic Clones ( 1 )
        hide cDNA Clones ( 39 )
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Source for merge of: l(1)G0003 CG6606 l(1)G0297 l(1)G0070 l(1)G0092 l(1)G0205
        (Peter et al., 2002)
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •