FB2020_06, released Dec 22, 2020

Gene: Dmel\jim

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General Information
Symbol
Dmel\jim
Species
D. melanogaster
Name
jim
Annotation Symbol
CG11352
Feature Type
protein_coding_gene
FlyBase ID
FBgn0027339
Gene Model Status
Current
Stock Availability
20 publicly available
Gene Snapshot
jim (jim) encodes a zinc finger C2H2 transcription factor involved in dendrite morphogenesis and regulation of chromatin silencing. [Date last reviewed: 2019-07-11]
Other Summaries
Also Known As

ovfc.K, ovk

Key Links
Genomic Location
Cytogenetic map
80A2-80A4
Sequence location
3L:22,789,233..22,835,194 [-]
Recombination map

3-47

RefSeq locus
NT_037436 REGION:22789233..22835194
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (6 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables DNA-binding transcription factor activity, RNA polymerase II-specific
inferred from biological aspect of ancestor with PANTHER:PTN002810793
(assigned by GO_Central )
(Gaudet et al., 2011)
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN002810793
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in dendrite morphogenesis
inferred from mutant phenotype
(Iyer et al., 2013)
involved_in regulation of chromatin silencing
inferred from mutant phenotype
(Schneiderman et al., 2010)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in regulation of transcription, DNA-templated
inferred from biological aspect of ancestor with PANTHER:PTN002810793
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
colocalizes_with chromatin
inferred from biological aspect of ancestor with PANTHER:PTN002810793
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
Gene Model and Products
Number of Transcripts
7
Number of Unique Polypeptides
5

Please see the JBrowse view of Dmel\jim for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.44

Stop-codon suppression (UGA) postulated; FBrf0216884.

gene_with_stop_codon_read_through ; SO:0000697

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.46

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Sequence Ontology: Class of Gene
gene_with_edited_transcript
(Rodriguez et al., 2012)
gene_with_stop_codon_read_through
(Jungreis et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
jim-RC
FBtr0078582
NM_143699
13458
820
jim-RD
FBtr0100184
NM_001014601
4749
820
jim-RE
FBtr0304985
NM_001259959
12379
825
jim-RF
FBtr0330076
NM_001275292
6714
938
jim-RG
FBtr0333211
NM_001275293
5542
794
jim-RH
FBtr0333212
NM_168964
5620
820
jim-RI
FBtr0333213
NM_001275294
6193
792
Additional Transcript Data and Comments
Reported size (kB)

6.5, 5.5 (northern blot)

(Doerflinger et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
jim-PC
FBpp0078231
89.1
820
8.87
NP_651956
AAF51862
jim-PD
FBpp0099541
89.1
820
8.87
NP_001014601
AAX52769
jim-PE
FBpp0293522
89.7
825
8.87
NP_001246888
AFH04559
jim-PF
FBpp0303109
100.8
938
8.87
NP_001262221
AGB94914
jim-PG
FBpp0305413
86.1
794
8.76
NP_001262222
AGB94915
jim-PH
FBpp0305414
89.1
820
8.87
NP_730746
AAN12203
jim-PI
FBpp0305415
85.9
792
8.76
NP_001262223
AGB94916
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

820 aa isoforms: jim-PC, jim-PD, jim-PH
Additional Polypeptide Data and Comments
Reported size (kDa)

820 (aa); 115 (kD observed)

(Doerflinger et al., 1999)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\jim using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 15
embryonic/larval hindgut
(Doerflinger et al., 1999)
embryonic/larval anterior midgut
(Doerflinger et al., 1999)
pharyngeal muscle
(Doerflinger et al., 1999)
adult stageoogenesis stage S9 -- S14
stretch follicle cell
(Doerflinger et al., 1999)
adult stageoogenesis stage S10 -- S14
main body follicle cell
(Doerflinger et al., 1999)
Additional Descriptive Data

jim protein is detected from stage 10 of oogenesis in the non-antero-dorsal columnar follicle cells. It is also detected in squamous cells from stage 9 onward and in a single row of 10-15 antero-dorsal columnar cells in stage 12 follicles. In stage 15 embryos, jim protein accumulates in the anterior midgut and hindgut and in glossopharyngeal muscles.

(Doerflinger et al., 1999)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
Reporter: P{lacW}jimOVK
Stage
Tissue/Position (including subcellular localization)
Reference
adult stageoogenesis stage S10 -- S14
main body follicle cell
(Doerflinger et al., 1999)
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\jim in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 38 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of jim
Transgenic constructs containing regulatory region of jim
Deletions and Duplications ( 0 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (71)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ZNF133
2 of 15
Yes
Yes
Hsap\ZNF343
2 of 15
Yes
Yes
Hsap\ZNF460
2 of 15
Yes
Yes
Hsap\ZNF708
2 of 15
Yes
Yes
Hsap\ZNF724
2 of 15
Yes
Yes
Hsap\GZF1
1 of 15
No
Yes
Hsap\MZF1
1 of 15
No
No
Hsap\ZBTB11
1 of 15
No
Yes
Hsap\ZNF7
1 of 15
No
No
Hsap\ZNF66
1 of 15
No
Yes
Hsap\ZNF84
1 of 15
No
No
Hsap\ZNF85
1 of 15
No
No
Hsap\ZNF90
1 of 15
No
Yes
Hsap\ZNF92
1 of 15
No
Yes
Hsap\ZNF98
1 of 15
No
No
Hsap\ZNF99
1 of 15
No
No
Hsap\ZNF100
1 of 15
No
Yes
Hsap\ZNF114
1 of 15
No
Yes
Hsap\ZNF117
1 of 15
No
Yes
Hsap\ZNF138
1 of 15
No
Yes
Hsap\ZNF141
1 of 15
No
Yes
Hsap\ZNF195
1 of 15
No
No
Hsap\ZNF234
1 of 15
No
No
Hsap\ZNF253
1 of 15
No
Yes
Hsap\ZNF257
1 of 15
No
Yes
Hsap\ZNF273
1 of 15
No
Yes
Hsap\ZNF331
1 of 15
No
Yes
Hsap\ZNF429
1 of 15
No
No
Hsap\ZNF430
1 of 15
No
Yes
Hsap\ZNF431
1 of 15
No
Yes
Hsap\ZNF479
1 of 15
No
Yes
Hsap\ZNF486
1 of 15
No
Yes
Hsap\ZNF492
1 of 15
No
No
Hsap\ZNF502
1 of 15
No
Yes
Hsap\ZNF506
1 of 15
No
Yes
Hsap\ZNF519
1 of 15
No
Yes
Hsap\ZNF530
1 of 15
No
No
Hsap\ZNF543
1 of 15
No
No
Hsap\ZNF546
1 of 15
No
No
Hsap\ZNF562
1 of 15
No
Yes
Hsap\ZNF595
1 of 15
No
No
Hsap\ZNF626
1 of 15
No
Yes
Hsap\ZNF628
1 of 15
No
No
Hsap\ZNF629
1 of 15
No
Yes
Hsap\ZNF646
1 of 15
No
Yes
Hsap\ZNF664
1 of 15
No
Yes
Hsap\ZNF675
1 of 15
No
No
Hsap\ZNF676
1 of 15
No
No
Hsap\ZNF678
1 of 15
No
No
Hsap\ZNF679
1 of 15
No
Yes
Hsap\ZNF680
1 of 15
No
No
Hsap\ZNF681
1 of 15
No
No
Hsap\ZNF682
1 of 15
No
Yes
Hsap\ZNF695
1 of 15
No
Yes
Hsap\ZNF713
1 of 15
No
Yes
Hsap\ZNF714
1 of 15
No
Yes
Hsap\ZNF716
1 of 15
No
Yes
Hsap\ZNF718
1 of 15
No
Yes
Hsap\ZNF723
1 of 15
No
Yes
Hsap\ZNF727
1 of 15
No
No
Hsap\ZNF729
1 of 15
No
No
Hsap\ZNF730
1 of 15
No
Yes
Hsap\ZNF732
1 of 15
No
Yes
Hsap\ZNF735
1 of 15
No
Yes
Hsap\ZNF736
1 of 15
No
Yes
Hsap\ZNF737
1 of 15
No
No
Hsap\ZNF826P
1 of 15
No
Yes
Hsap\ZNF875
1 of 15
No
Yes
Hsap\ZNF876P
1 of 15
No
Yes
Hsap\ZXDA
1 of 15
No
Yes
Hsap\ZXDC
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (18)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Gm19965
1 of 15
Yes
Yes
Mmus\Mzf1
1 of 15
Yes
No
Mmus\Sall2
1 of 15
Yes
No
Mmus\Zbtb11
1 of 15
Yes
Yes
Mmus\Zfp11
1 of 15
Yes
No
Mmus\Zfp169
1 of 15
Yes
Yes
Mmus\Zfp467
1 of 15
Yes
Yes
Mmus\Zfp646
1 of 15
Yes
Yes
Mmus\Zfp664
1 of 15
Yes
Yes
Mmus\Zfp712
1 of 15
Yes
No
Mmus\Zfp715
1 of 15
Yes
No
Mmus\Zfp719
1 of 15
Yes
No
Mmus\Zfp729a
1 of 15
Yes
No
Mmus\Zfp748
1 of 15
Yes
No
Mmus\Zfp768
1 of 15
Yes
Yes
Mmus\Zfp773
1 of 15
Yes
Yes
Mmus\Zfp780b
1 of 15
Yes
No
Mmus\Zfp977
1 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (14)
Rnor\Gzf1
1 of 13
Yes
Yes
Rnor\LOC102556092
1 of 13
Yes
Yes
Rnor\LOC102556967
1 of 13
Yes
Yes
Rnor\Mzf1
1 of 13
Yes
Yes
Rnor\Sall2
1 of 13
Yes
No
Rnor\Zbtb11
1 of 13
Yes
Yes
Rnor\Zfp17
1 of 13
Yes
No
Rnor\Zfp52
1 of 13
Yes
No
Rnor\Zfp143
1 of 13
Yes
Yes
Rnor\Zfp418
1 of 13
Yes
No
Rnor\Zfp467
1 of 13
Yes
Yes
Rnor\Zfp646
1 of 13
Yes
Yes
Rnor\Zfp773-ps1
1 of 13
Yes
Yes
Rnor\Zfp958
1 of 13
Yes
No
Xenopus tropicalis (Western clawed frog) (5)
Xtro\LOC101732255
1 of 12
Yes
Yes
Xtro\prdm5
1 of 12
Yes
Yes
Xtro\zbtb16
1 of 12
Yes
Yes
Xtro\zbtb39
1 of 12
Yes
Yes
Xtro\znf646
1 of 12
Yes
Yes
Danio rerio (Zebrafish) (49)
Drer\zgc:174646
2 of 15
Yes
Yes
Drer\im:7143333
1 of 15
No
Yes
Drer\itpr1a
1 of 15
No
No
Drer\LOC100148466
1 of 15
No
Yes
Drer\LOC101883008
1 of 15
No
Yes
Drer\LOC101884305
1 of 15
No
Yes
Drer\LOC103910729
1 of 15
No
Yes
Drer\LOC103910825
1 of 15
No
Yes
Drer\LOC108182290
1 of 15
No
Yes
Drer\LOC108182318
1 of 15
No
Yes
Drer\LOC108182721
1 of 15
No
Yes
Drer\si:cabz01021433.2
1 of 15
No
Yes
Drer\si:cabz01063885.1
1 of 15
No
Yes
Drer\si:ch211-207i20.2
1 of 15
No
Yes
Drer\si:ch211-235i11.4
1 of 15
No
Yes
Drer\si:dkey-1b17.6
1 of 15
No
Yes
Drer\si:dkey-40j3.3
1 of 15
No
Yes
Drer\si:dkey-57k17.1
1 of 15
No
Yes
Drer\si:dkey-89b17.4
1 of 15
No
Yes
Drer\si:dkey-172k15.13
1 of 15
No
Yes
Drer\si:dkey-201g16.1
1 of 15
No
Yes
Drer\si:dkey-253d23.2
1 of 15
No
Yes
Drer\si:dkeyp-2e4.8
1 of 15
No
Yes
Drer\zbtb47a
1 of 15
No
No
Drer\zgc:66448
1 of 15
No
Yes
Drer\zgc:173615
1 of 15
No
Yes
Drer\zgc:173619
1 of 15
No
Yes
Drer\zgc:173693
1 of 15
No
Yes
Drer\zgc:174275
1 of 15
No
Yes
Drer\zgc:174650
1 of 15
No
Yes
Drer\zgc:174698
1 of 15
No
Yes
Drer\zgc:194215
1 of 15
No
Yes
Drer\znf408
1 of 15
No
Yes
Drer\znf628
1 of 15
No
Yes
Drer\znf646
1 of 15
No
Yes
Drer\znf865
1 of 15
No
No
Drer\znf973
1 of 15
No
Yes
Drer\znf977
1 of 15
No
Yes
Drer\znf1023
1 of 15
No
Yes
Drer\znf1085
1 of 15
No
Yes
Drer\znf1086
1 of 15
No
Yes
Drer\znf1102
1 of 15
No
Yes
Drer\znf1113
1 of 15
No
Yes
Drer\znf1117
1 of 15
No
Yes
Drer\znf1119
1 of 15
No
Yes
Drer\znf1136
1 of 15
No
Yes
Drer\znf1137
1 of 15
No
Yes
Drer\znf1140
1 of 15
No
Yes
Drer\znf1141
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (4)
Cele\asd-1
1 of 15
Yes
No
Cele\fox-1
1 of 15
Yes
No
Cele\Y55F3AM.14
1 of 15
Yes
No
Cele\ztf-23
1 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\MET31
1 of 15
Yes
Yes
Scer\MET32
1 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091904FN )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00007655
Drosophila simulans
Dsim\GD12054
Drosophila sechellia
Dsec\GM22079
Drosophila erecta
Dere\GG13168
Drosophila yakuba
Dyak\GE19490
Drosophila ananassae
Dana\GF23446
Drosophila pseudoobscura pseudoobscura
Dpse\GA10941
Drosophila persimilis
Dper\GL25186
Drosophila willistoni
Dwil\GK20499
Drosophila virilis
Dvir\GJ13563
Drosophila mojavensis
Dmoj\GI11869
Drosophila grimshawi
Dgri\GH14766
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503SV )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17024361
Glossina morsitans
Tsetse fly
Gmor\GMOY001310
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_10643
Mayetiola destructor
Hessian fly
Mdes\Mdes014077
Mayetiola destructor
Hessian fly
Mdes\Mdes011657
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL008573
Anopheles darlingi
American malaria mosquito
Adar\ADAC007055
Anopheles gambiae
Malaria mosquito
Agam\AGAP011544
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ015000
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W01YA )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA011610
Danaus plexippus
Monarch butterfly
Dple\DPOGS212967-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL011306
Apis florea
Little honeybee
Aflo\3513809956
Apis mellifera
Western honey bee
Amel\GB54239
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP10674
Bombus terrestris
Buff-tailed bumblebee
Bter\15213467
Linepithema humile
Argentine ant
Lhum\LH25949
Linepithema humile
Argentine ant
Lhum\LH25950
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG009964
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_06743
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_06744
Tribolium castaneum
Red flour beetle
Tcas\TC002621
Tribolium castaneum
Red flour beetle
Tcas\TC002620
Pediculus humanus
Human body louse
Phum\PHUM041520
Rhodnius prolixus
Kissing bug
Rpro\RPRC001284
Cimex lectularius
Bed bug
Clec\CLEC004496
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002850
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_04014
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X01VY )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Ixodes scapularis
Black-legged tick
Isca\ISCW019865
Ixodes scapularis
Black-legged tick
Isca\ISCW019866
Ixodes scapularis
Black-legged tick
Isca\ISCW019860
Ixodes scapularis
Black-legged tick
Isca\ISCW019861
Ixodes scapularis
Black-legged tick
Isca\ISCW019867
Ixodes scapularis
Black-legged tick
Isca\ISCW019864
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65920.1
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_44467
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (14)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG4360
2 of 10
CG4424
1 of 10
CG4854
1 of 10
CG5245
1 of 10
CG9215
1 of 10
CG15269
1 of 10
CG18011
1 of 10
cg
1 of 10
CkIIα-i1
1 of 10
dwg
1 of 10
grau
1 of 10
Meics
1 of 10
trem
1 of 10
Zaf1
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Interactions Browser
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement
    View in Interactions Browser
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    bw
    enhanceable
    jim
    (Schneiderman et al., 2010)
    upd1
    enhanceable
    jim
    (Mukherjee et al., 2006)
    upd1
    suppressible
    jim
    (Mukherjee et al., 2006)
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    3L
    Recombination map

    3-47

    Cytogenetic map
    80A2-80A4
    Sequence location
    3L:22,789,233..22,835,194 [-]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    80A2-80A4
    Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    79F-79F
    (determined by in situ hybridisation)
    (Doerflinger et al., 1998)
    79F-79F
    (Doerflinger, 1996.4.29)
    Experimentally Determined Recombination Data
    Location

    3-47

    (FlyBase, 2016)

    3-44.0

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (20)
    Genomic Clones (33)
    cDNA Clones (54)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    Other clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
     

    polyclonal

    (Doerflinger et al., 1999)
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of
    Source for database merge of

    Source for merge of: jim ovfc.k ovk

    (Doerflinger et al., 1999)

    Source for merge of: jim CG11352

    (Bayraktaroglu, 2000.4.12)

    Source for merge of: jim BcDNA:SD14927

    (FlyBase, 1996-)
    Additional comments

    Source for merge of jim BcDNA:SD14927 was a shared cDNA ( date:030728 ).

    (FlyBase, 1996-)
    Other Comments

    Identification: Enhancer trap screen for genes expressed in follicle cells.

    (Doerflinger et al., 1998)

    Isolated as an enhancer-trap expressed in ovarian follicles at stage 10.

    (Doerflinger et al., 1996)
    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 79 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    InterPro - A database of protein families, domains and functional sites
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
    FlyMine - An integrated database for Drosophila genomics
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Synonyms and Secondary IDs (7)
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
    Project Type
    Title
    References (73)