Dfz3, EG:34F3.6 , Dfrizzled-3
transmembrane - 7 pass - frizzled family - antagonizes wingless signal
Please see the JBrowse view of Dmel\fz3 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
Gene model reviewed during 5.56
2.1 (longest cDNA)
581 (aa)
The FZ domain is involved in binding with Wnt ligands.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\fz3 using the Feature Mapper tool.
Comment: within ~6 cell diameters both dorsal and ventral of wg signaling
Expression of fz3 transcript can be first detected at embryonic stage 9.
GBrowse - Visual display of RNA-Seq signals
View Dmel\fz3 in GBrowse 21-0
1-0.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: fz3 CG16785
Source for merge of: fz3 EG:34F3.6
Source for merge of fz3 EG:34F3.6 was sequence comparison ( date:000202 ).